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Results: 1 to 20 of 74

1.

Increase of microRNA-210, Decrease of Raptor Gene Expression and Alteration of Mammalian Target of Rapamycin Regulated Proteins following Mithramycin Treatment of Human Erythroid Cells.

Bianchi N, Finotti A, Ferracin M, Lampronti I, Zuccato C, Breveglieri G, Brognara E, Fabbri E, Borgatti M, Negrini M, Gambari R.

PLoS One. 2015 Apr 7;10(4):e0121567. doi: 10.1371/journal.pone.0121567. eCollection 2015.

2.

Recent trends in the gene therapy of β-thalassemia.

Finotti A, Breda L, Lederer CW, Bianchi N, Zuccato C, Kleanthous M, Rivella S, Gambari R.

J Blood Med. 2015 Feb 19;6:69-85. doi: 10.2147/JBM.S46256. eCollection 2015. Review.

3.

Erythroid differentiation ability of butyric acid analogues: identification of basal chemical structures of new inducers of foetal haemoglobin.

Bianchi N, Chiarabelli C, Zuccato C, Lampronti I, Borgatti M, Amari G, Delcanale M, Chiavilli F, Prus E, Fibach E, Gambari R.

Eur J Pharmacol. 2015 Apr 5;752:84-91. doi: 10.1016/j.ejphar.2015.02.018. Epub 2015 Feb 19.

PMID:
25701725
4.

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses.

Sipione S, Rigamonti D, Valenza M, Zuccato C, Conti L, Pritchard J, Kooperberg C, Olson JM, Cattaneo E.

Hum Mol Genet. 2014 Nov 21. pii: ddu539. [Epub ahead of print] No abstract available.

PMID:
25416283
5.

Disruption of astrocyte-neuron cholesterol cross talk affects neuronal function in Huntington's disease.

Valenza M, Marullo M, Di Paolo E, Cesana E, Zuccato C, Biella G, Cattaneo E.

Cell Death Differ. 2015 Apr;22(4):690-702. doi: 10.1038/cdd.2014.162. Epub 2014 Oct 10.

PMID:
25301063
6.

Forkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loop.

Kannike K, Sepp M, Zuccato C, Cattaneo E, Timmusk T.

J Biol Chem. 2014 Nov 21;289(47):32845-57. doi: 10.1074/jbc.M114.612424. Epub 2014 Sep 30.

7.

Huntington's disease.

Zuccato C, Cattaneo E.

Handb Exp Pharmacol. 2014;220:357-409. doi: 10.1007/978-3-642-45106-5_14. Review.

PMID:
24668480
8.

Repressor element-1 silencing transcription factor (REST) is present in human control and Huntington's disease neurones.

Schiffer D, Caldera V, Mellai M, Conforti P, Cattaneo E, Zuccato C.

Neuropathol Appl Neurobiol. 2014 Dec;40(7):899-910. doi: 10.1111/nan.12137.

PMID:
24634989
9.

Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors.

Crotti A, Benner C, Kerman BE, Gosselin D, Lagier-Tourenne C, Zuccato C, Cattaneo E, Gage FH, Cleveland DW, Glass CK.

Nat Neurosci. 2014 Apr;17(4):513-21. doi: 10.1038/nn.3668. Epub 2014 Mar 2.

10.

Binding of the repressor complex REST-mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models.

Conforti P, Zuccato C, Gaudenzi G, Ieraci A, Camnasio S, Buckley NJ, Mutti C, Cotelli F, Contini A, Cattaneo E.

J Neurochem. 2013 Oct;127(1):22-35. doi: 10.1111/jnc.12348. Epub 2013 Jul 19.

PMID:
23800350
11.

Combining gene therapy and fetal hemoglobin induction for treatment of β-thalassemia.

Breda L, Rivella S, Zuccato C, Gambari R.

Expert Rev Hematol. 2013 Jun;6(3):255-64. doi: 10.1586/ehm.13.24.

PMID:
23782080
12.

Tobramycin is a suppressor of premature termination codons.

Altamura N, Castaldo R, Finotti A, Breveglieri G, Salvatori F, Zuccato C, Gambari R, Panin GC, Borgatti M.

J Cyst Fibros. 2013 Dec;12(6):806-11. doi: 10.1016/j.jcf.2013.02.007. Epub 2013 Mar 27.

PMID:
23540394
13.

Induction of erythroid differentiation and increased globin mRNA production with furocoumarins and their photoproducts.

Salvador A, Brognara E, Vedaldi D, Castagliuolo I, Brun P, Zuccato C, Lampronti I, Gambari R.

J Photochem Photobiol B. 2013 Apr 5;121:57-66. doi: 10.1016/j.jphotobiol.2013.02.011. Epub 2013 Feb 27.

14.

In vivo delivery of DN:REST improves transcriptional changes of REST-regulated genes in HD mice.

Conforti P, Mas Monteys A, Zuccato C, Buckley NJ, Davidson B, Cattaneo E.

Gene Ther. 2013 Jun;20(6):678-85. doi: 10.1038/gt.2012.84. Epub 2012 Nov 15.

PMID:
23151521
15.

Pitfalls in the detection of cholesterol in Huntington's disease models.

Marullo M, Valenza M, Leoni V, Caccia C, Scarlatti C, De Mario A, Zuccato C, Di Donato S, Carafoli E, Cattaneo E.

PLoS Curr. 2012 Oct 11;4:e505886e9a1968. doi: 10.1371/505886e9a1968.

16.

Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death.

Conforti P, Camnasio S, Mutti C, Valenza M, Thompson M, Fossale E, Zeitlin S, MacDonald ME, Zuccato C, Cattaneo E.

Neurobiol Dis. 2013 Feb;50:160-70. doi: 10.1016/j.nbd.2012.10.015. Epub 2012 Oct 23.

PMID:
23089356
17.

NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease.

Pouladi MA, Brillaud E, Xie Y, Conforti P, Graham RK, Ehrnhoefer DE, Franciosi S, Zhang W, Poucheret P, Compte E, Maurel JC, Zuccato C, Cattaneo E, Néri C, Hayden MR.

Neurobiol Dis. 2012 Dec;48(3):282-9. doi: 10.1016/j.nbd.2012.06.026. Epub 2012 Jul 10.

PMID:
22796360
18.

An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin.

Lo Sardo V, Zuccato C, Gaudenzi G, Vitali B, Ramos C, Tartari M, Myre MA, Walker JA, Pistocchi A, Conti L, Valenza M, Drung B, Schmidt B, Gusella J, Zeitlin S, Cotelli F, Cattaneo E.

Nat Neurosci. 2012 May;15(5):713-21. doi: 10.1038/nn.3080.

PMID:
22466506
19.

A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction.

Zuccato C, Breda L, Salvatori F, Breveglieri G, Gardenghi S, Bianchi N, Brognara E, Lampronti I, Borgatti M, Rivella S, Gambari R.

Ann Hematol. 2012 Aug;91(8):1201-13. doi: 10.1007/s00277-012-1430-5. Epub 2012 Mar 31.

20.

The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity.

Camnasio S, Delli Carri A, Lombardo A, Grad I, Mariotti C, Castucci A, Rozell B, Lo Riso P, Castiglioni V, Zuccato C, Rochon C, Takashima Y, Diaferia G, Biunno I, Gellera C, Jaconi M, Smith A, Hovatta O, Naldini L, Di Donato S, Feki A, Cattaneo E.

Neurobiol Dis. 2012 Apr;46(1):41-51. doi: 10.1016/j.nbd.2011.12.042.

PMID:
22405424
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