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Items: 1 to 20 of 97

1.

Synthesis of [11C]MK-1064 as a new PET radioligand for imaging of orexin-2 receptor.

Gao M, Wang M, Zheng QH.

Bioorg Med Chem Lett. 2016 May 28. pii: S0960-894X(16)30595-9. doi: 10.1016/j.bmcl.2016.05.083. [Epub ahead of print]

PMID:
27268698
2.

Synthesis of carbon-11-labeled imidazopyridine- and purine-thioacetamide derivatives as new potential PET tracers for imaging of nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1).

Gao M, Wang M, Zheng QH.

Bioorg Med Chem Lett. 2016 Mar 1;26(5):1371-5. doi: 10.1016/j.bmcl.2016.01.081. Epub 2016 Feb 1.

PMID:
26856922
3.

Synthesis of a PET tau tracer [(11)C]PBB3 for imaging of Alzheimer's disease.

Wang M, Gao M, Xu Z, Zheng QH.

Bioorg Med Chem Lett. 2015 Oct 15;25(20):4587-92. doi: 10.1016/j.bmcl.2015.08.053. Epub 2015 Aug 20.

PMID:
26323870
4.

Synthesis of [11C]CX-6258 as a new PET tracer for imaging of Pim kinases in cancer.

Wang M, Tzintzun R, Gao M, Xu Z, Zheng QH.

Bioorg Med Chem Lett. 2015 Sep 15;25(18):3831-5. doi: 10.1016/j.bmcl.2015.07.061. Epub 2015 Jul 26.

PMID:
26227775
5.

Fully automated synthesis of [(18)F]T807, a PET tau tracer for Alzheimer's disease.

Gao M, Wang M, Zheng QH.

Bioorg Med Chem Lett. 2015 Aug 1;25(15):2953-7. doi: 10.1016/j.bmcl.2015.05.035. Epub 2015 May 21.

PMID:
26048805
6.

Synthesis of [(11)C]GSK1482160 as a new PET agent for targeting P2X(7) receptor.

Gao M, Wang M, Green MA, Hutchins GD, Zheng QH.

Bioorg Med Chem Lett. 2015 May 1;25(9):1965-70. doi: 10.1016/j.bmcl.2015.03.021. Epub 2015 Mar 14.

PMID:
25819093
7.

Synthesis of carbon-11-labeled aminoalkylindole derivatives as new candidates of cannabinoid receptor radioligands for PET imaging of alcohol abuse.

Gao M, Gao AC, Wang M, Zheng QH.

Bioorg Med Chem Lett. 2014 Dec 15;24(24):5581-6. doi: 10.1016/j.bmcl.2014.10.097. Epub 2014 Nov 6.

PMID:
25466179
8.

The first radiosynthesis of [(11)C]AZD8931 as a new potential PET agent for imaging of EGFR, HER2 and HER3 signaling.

Wang M, Gao M, Zheng QH.

Bioorg Med Chem Lett. 2014 Sep 15;24(18):4455-9. doi: 10.1016/j.bmcl.2014.07.092. Epub 2014 Aug 8.

PMID:
25149507
9.

Synthesis of carbon-11-labeled 4-(phenylamino)-pyrrolo[2,1-f][1,2,4]triazine derivatives as new potential PET tracers for imaging of p38α mitogen-activated protein kinase.

Wang M, Gao M, Zheng QH.

Bioorg Med Chem Lett. 2014 Aug 15;24(16):3700-5. doi: 10.1016/j.bmcl.2014.07.017. Epub 2014 Jul 12.

PMID:
25065491
10.

Simple synthesis of new carbon-11-labeled 1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives for PET imaging of A₃ adenosine receptor.

Gao M, Gao AC, Wang M, Zheng QH.

Appl Radiat Isot. 2014 Sep;91:71-8. doi: 10.1016/j.apradiso.2014.05.005. Epub 2014 May 21.

PMID:
24908190
11.

Facile and high-yield synthesis of N-(4-diethylamino)benzyl-4-[¹¹C]methoxy-N-(p-tolyl)benzenesulfonamide as a new potential PET selective CB2 radioligand.

Gao M, Xu J, Wang M, Zheng QH.

Appl Radiat Isot. 2014 Aug;90:181-6. doi: 10.1016/j.apradiso.2014.03.029. Epub 2014 Apr 5.

PMID:
24768996
12.

Synthesis of a new fluorine-18-labeled bexarotene analogue for PET imaging of retinoid X receptor.

Wang M, Davis T, Gao M, Zheng QH.

Bioorg Med Chem Lett. 2014 Apr 1;24(7):1742-7. doi: 10.1016/j.bmcl.2014.02.037. Epub 2014 Feb 24.

PMID:
24602901
13.

Concise and high-yield synthesis of T808 and T808P for radiosynthesis of [(18)F]-T808, a PET tau tracer for Alzheimer's disease.

Gao M, Wang M, Zheng QH.

Bioorg Med Chem Lett. 2014 Jan 1;24(1):254-7. doi: 10.1016/j.bmcl.2013.11.025. Epub 2013 Nov 20.

PMID:
24309505
14.

A high-yield route to synthesize the P-glycoprotein radioligand [11C]N-desmethyl-loperamide and its parent radioligand [11C]loperamide.

Wang M, Gao M, Zheng QH.

Bioorg Med Chem Lett. 2013 Oct 1;23(19):5259-63. doi: 10.1016/j.bmcl.2013.08.024. Epub 2013 Aug 13.

PMID:
23981899
15.

Synthesis of (Z)-2-((1H-indazol-3-yl)methylene)-6-[¹¹C]methoxy-7-(piperazin-1-ylmethyl)benzofuran-3(2H)-one as a new potential PET probe for imaging of the enzyme PIM1.

Gao M, Wang M, Miller KD, Zheng QH.

Bioorg Med Chem Lett. 2013 Aug 1;23(15):4342-6. doi: 10.1016/j.bmcl.2013.05.091. Epub 2013 Jun 6.

PMID:
23791570
16.

[11C]olanzapine, radiosynthesis and lipophilicity of a new potential PET 5-HT2 and D2 receptor radioligand.

Gao M, Shi Z, Wang M, Zheng QH.

Bioorg Med Chem Lett. 2013 Apr 1;23(7):1953-6. doi: 10.1016/j.bmcl.2013.02.045. Epub 2013 Feb 14.

PMID:
23466228
17.

Synthesis of radiolabeled protein disulfide isomerase (PDI) inhibitors as new potential PET agents for imaging of the enzyme PDI in neurological disorders and cancer.

Gao M, Yang Q, Wang M, Miller KD, Sledge GW, Zheng QH.

Appl Radiat Isot. 2013 Apr;74:61-9. doi: 10.1016/j.apradiso.2013.01.003. Epub 2013 Jan 8.

PMID:
23376309
18.

Synthesis of 2,6-difluoro-N-(3-[11C]methoxy-1H-pyrazolo[3,4-b]pyridine-5-yl)-3-(propylsulfonamidio)benzamide as a new potential PET agent for imaging of B-Raf(V600E) in cancers.

Wang M, Gao M, Miller KD, Zheng QH.

Bioorg Med Chem Lett. 2013 Feb 15;23(4):1017-21. doi: 10.1016/j.bmcl.2012.12.027. Epub 2012 Dec 20.

PMID:
23294704
19.

The first synthesis of [11C]J147, a new potential PET agent for imaging of Alzheimer's disease.

Wang M, Gao M, Zheng QH.

Bioorg Med Chem Lett. 2013 Jan 15;23(2):524-7. doi: 10.1016/j.bmcl.2012.11.031. Epub 2012 Nov 22.

PMID:
23237833
20.

Striatal D(2)/D(3) receptor availability is inversely correlated with cannabis consumption in chronic marijuana users.

Albrecht DS, Skosnik PD, Vollmer JM, Brumbaugh MS, Perry KM, Mock BH, Zheng QH, Federici LA, Patton EA, Herring CM, Yoder KK.

Drug Alcohol Depend. 2013 Feb 1;128(1-2):52-7. doi: 10.1016/j.drugalcdep.2012.07.016. Epub 2012 Aug 19.

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