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Results: 1 to 20 of 92

1.

Synthesis of [(11)C]GSK1482160 as a new PET agent for targeting P2X7 receptor.

Gao M, Wang M, Green MA, Hutchins GD, Zheng QH.

Bioorg Med Chem Lett. 2015 May 1;25(9):1965-70. doi: 10.1016/j.bmcl.2015.03.021. Epub 2015 Mar 14.

PMID:
25819093
2.

Synthesis of carbon-11-labeled aminoalkylindole derivatives as new candidates of cannabinoid receptor radioligands for PET imaging of alcohol abuse.

Gao M, Gao AC, Wang M, Zheng QH.

Bioorg Med Chem Lett. 2014 Dec 15;24(24):5581-6. doi: 10.1016/j.bmcl.2014.10.097. Epub 2014 Nov 6.

PMID:
25466179
3.

The first radiosynthesis of [(11)C]AZD8931 as a new potential PET agent for imaging of EGFR, HER2 and HER3 signaling.

Wang M, Gao M, Zheng QH.

Bioorg Med Chem Lett. 2014 Sep 15;24(18):4455-9. doi: 10.1016/j.bmcl.2014.07.092. Epub 2014 Aug 8.

PMID:
25149507
4.

Synthesis of carbon-11-labeled 4-(phenylamino)-pyrrolo[2,1-f][1,2,4]triazine derivatives as new potential PET tracers for imaging of p38α mitogen-activated protein kinase.

Wang M, Gao M, Zheng QH.

Bioorg Med Chem Lett. 2014 Aug 15;24(16):3700-5. doi: 10.1016/j.bmcl.2014.07.017. Epub 2014 Jul 12.

PMID:
25065491
5.

Simple synthesis of new carbon-11-labeled 1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives for PET imaging of A₃ adenosine receptor.

Gao M, Gao AC, Wang M, Zheng QH.

Appl Radiat Isot. 2014 Sep;91:71-8. doi: 10.1016/j.apradiso.2014.05.005. Epub 2014 May 21.

PMID:
24908190
6.

Facile and high-yield synthesis of N-(4-diethylamino)benzyl-4-[¹¹C]methoxy-N-(p-tolyl)benzenesulfonamide as a new potential PET selective CB2 radioligand.

Gao M, Xu J, Wang M, Zheng QH.

Appl Radiat Isot. 2014 Aug;90:181-6. doi: 10.1016/j.apradiso.2014.03.029. Epub 2014 Apr 5.

PMID:
24768996
7.

Synthesis of a new fluorine-18-labeled bexarotene analogue for PET imaging of retinoid X receptor.

Wang M, Davis T, Gao M, Zheng QH.

Bioorg Med Chem Lett. 2014 Apr 1;24(7):1742-7. doi: 10.1016/j.bmcl.2014.02.037. Epub 2014 Feb 24.

PMID:
24602901
8.

Concise and high-yield synthesis of T808 and T808P for radiosynthesis of [(18)F]-T808, a PET tau tracer for Alzheimer's disease.

Gao M, Wang M, Zheng QH.

Bioorg Med Chem Lett. 2014 Jan 1;24(1):254-7. doi: 10.1016/j.bmcl.2013.11.025. Epub 2013 Nov 20.

PMID:
24309505
9.

A high-yield route to synthesize the P-glycoprotein radioligand [11C]N-desmethyl-loperamide and its parent radioligand [11C]loperamide.

Wang M, Gao M, Zheng QH.

Bioorg Med Chem Lett. 2013 Oct 1;23(19):5259-63. doi: 10.1016/j.bmcl.2013.08.024. Epub 2013 Aug 13.

PMID:
23981899
10.

Synthesis of (Z)-2-((1H-indazol-3-yl)methylene)-6-[¹¹C]methoxy-7-(piperazin-1-ylmethyl)benzofuran-3(2H)-one as a new potential PET probe for imaging of the enzyme PIM1.

Gao M, Wang M, Miller KD, Zheng QH.

Bioorg Med Chem Lett. 2013 Aug 1;23(15):4342-6. doi: 10.1016/j.bmcl.2013.05.091. Epub 2013 Jun 6.

PMID:
23791570
11.

[11C]olanzapine, radiosynthesis and lipophilicity of a new potential PET 5-HT2 and D2 receptor radioligand.

Gao M, Shi Z, Wang M, Zheng QH.

Bioorg Med Chem Lett. 2013 Apr 1;23(7):1953-6. doi: 10.1016/j.bmcl.2013.02.045. Epub 2013 Feb 14.

PMID:
23466228
12.

Synthesis of radiolabeled protein disulfide isomerase (PDI) inhibitors as new potential PET agents for imaging of the enzyme PDI in neurological disorders and cancer.

Gao M, Yang Q, Wang M, Miller KD, Sledge GW, Zheng QH.

Appl Radiat Isot. 2013 Apr;74:61-9. doi: 10.1016/j.apradiso.2013.01.003. Epub 2013 Jan 8.

PMID:
23376309
13.

Synthesis of 2,6-difluoro-N-(3-[11C]methoxy-1H-pyrazolo[3,4-b]pyridine-5-yl)-3-(propylsulfonamidio)benzamide as a new potential PET agent for imaging of B-Raf(V600E) in cancers.

Wang M, Gao M, Miller KD, Zheng QH.

Bioorg Med Chem Lett. 2013 Feb 15;23(4):1017-21. doi: 10.1016/j.bmcl.2012.12.027. Epub 2012 Dec 20.

PMID:
23294704
14.

The first synthesis of [11C]J147, a new potential PET agent for imaging of Alzheimer's disease.

Wang M, Gao M, Zheng QH.

Bioorg Med Chem Lett. 2013 Jan 15;23(2):524-7. doi: 10.1016/j.bmcl.2012.11.031. Epub 2012 Nov 22.

PMID:
23237833
15.

Striatal D(2)/D(3) receptor availability is inversely correlated with cannabis consumption in chronic marijuana users.

Albrecht DS, Skosnik PD, Vollmer JM, Brumbaugh MS, Perry KM, Mock BH, Zheng QH, Federici LA, Patton EA, Herring CM, Yoder KK.

Drug Alcohol Depend. 2013 Feb 1;128(1-2):52-7. doi: 10.1016/j.drugalcdep.2012.07.016. Epub 2012 Aug 19.

16.

Simple synthesis of carbon-11-labeled chromen-4-one derivatives as new potential PET agents for imaging of DNA-dependent protein kinase (DNA-PK) in cancer.

Gao M, Wang M, Miller KD, Zheng QH.

Appl Radiat Isot. 2012 Aug;70(8):1558-63. doi: 10.1016/j.apradiso.2012.04.023. Epub 2012 Apr 27.

PMID:
22732390
17.

A new facile synthetic route to [11C]GSK189254, a selective PET radioligand for imaging of CNS histamine H3 receptor.

Wang M, Gao M, Steele BL, Glick-Wilson BE, Brown-Proctor C, Shekhar A, Hutchins GD, Zheng QH.

Bioorg Med Chem Lett. 2012 Jul 15;22(14):4713-8. doi: 10.1016/j.bmcl.2012.05.076. Epub 2012 May 26.

PMID:
22687746
18.

Synthesis of 2-[11C]methoxy-3,17β-O,O-bis(sulfamoyl)estradiol as a new potential PET agent for imaging of steroid sulfatase (STS) in cancers.

Wang M, Xu L, Gao M, Miller KD, Sledge GW, Zheng QH.

Steroids. 2012 Jul;77(8-9):864-70. doi: 10.1016/j.steroids.2012.04.007. Epub 2012 Apr 19.

PMID:
22542502
19.

A new high-yield synthetic route to PET CB1 radioligands [11C]OMAR and its analogs.

Gao M, Wang M, Zheng QH.

Bioorg Med Chem Lett. 2012 Jun 1;22(11):3704-9. doi: 10.1016/j.bmcl.2012.04.030. Epub 2012 Apr 11.

PMID:
22542014
20.

Fully automated synthesis of PET TSPO radioligands [11C]DAA1106 and [18F]FEDAA1106.

Wang M, Gao M, Zheng QH.

Appl Radiat Isot. 2012 Jun;70(6):965-73. doi: 10.1016/j.apradiso.2012.03.011. Epub 2012 Mar 14.

PMID:
22469868
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