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Results: 1 to 20 of 114

1.

P197Neuropilin (NRP) 1 hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis.

Zachary I, Fantin A, Herzog B, Mahmoud M, Yamaji M, Plein A, Denti L, Ruhrberg C.

Cardiovasc Res. 2014 Jul 15;103 Suppl 1:S35. doi: 10.1093/cvr/cvu082.132. Epub 2014 Jun 27.

PMID:
25020614
[PubMed - in process]
2.

Local Over-Expression of VEGF-DΔNΔC in the Uterine Arteries of Pregnant Sheep Results in Long-Term Changes in Uterine Artery Contractility and Angiogenesis.

Mehta V, Abi-Nader KN, Shangaris P, Shaw SW, Filippi E, Benjamin E, Boyd M, Peebles DM, Martin J, Zachary I, David AL.

PLoS One. 2014 Jun 30;9(6):e100021. doi: 10.1371/journal.pone.0100021. eCollection 2014.

PMID:
24977408
[PubMed - in process]
Free PMC Article
3.

VEGF-A isoforms differentially regulate ATF-2-dependent VCAM-1 gene expression and endothelial-leukocyte interactions.

Fearnley GW, Odell AF, Latham AM, Mughal NA, Bruns AF, Burgoyne NJ, Homer-Vanniasinkam S, Zachary IC, Hollstein MC, Wheatcroft SB, Ponnambalam S.

Mol Biol Cell. 2014 Jun 25. pii: mbc.E14-05-0962. [Epub ahead of print]

PMID:
24966171
[PubMed - as supplied by publisher]
4.

Endosome-to-Plasma Membrane Recycling of VEGFR2 Receptor Tyrosine Kinase Regulates Endothelial Function and Blood Vessel Formation.

Jopling HM, Odell AF, Pellet-Many C, Latham AM, Frankel P, Sivaprasadarao A, Walker JH, Zachary IC, Ponnambalam S.

Cells. 2014 Apr 29;3(2):363-85. doi: 10.3390/cells3020363.

PMID:
24785348
[PubMed]
Free PMC Article
5.

N-terminal modification of VEGF-A C terminus-derived peptides delineates structural features involved in neuropilin-1 binding and functional activity.

Jia H, Aqil R, Cheng L, Chapman C, Shaikh S, Jarvis A, Chan AW, Hartzoulakis B, Evans IM, Frolov A, Martin J, Frankel P, Djordevic S, Zachary IC, Selwood DL.

Chembiochem. 2014 May 26;15(8):1161-70. doi: 10.1002/cbic.201300658. Epub 2014 Apr 25.

PMID:
24771685
[PubMed - in process]
6.

A crucial role for DOK1 in PDGF-BB-stimulated glioma cell invasion through p130Cas and Rap1 signalling.

Barrett A, Evans IM, Frolov A, Britton G, Pellet-Many C, Yamaji M, Mehta V, Bandopadhyay R, Li N, Brandner S, Zachary IC, Frankel P.

J Cell Sci. 2014 Jun 15;127(Pt 12):2647-58. doi: 10.1242/jcs.135988. Epub 2014 Apr 24.

PMID:
24762811
[PubMed - in process]
7.

Uteroplacental adenovirus vascular endothelial growth factor gene therapy increases fetal growth velocity in growth-restricted sheep pregnancies.

Carr DJ, Wallace JM, Aitken RP, Milne JS, Mehta V, Martin JF, Zachary IC, Peebles DM, David AL.

Hum Gene Ther. 2014 Apr;25(4):375-84. doi: 10.1089/hum.2013.214. Epub 2014 Apr 7.

PMID:
24593228
[PubMed - in process]
Free PMC Article
8.

Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis.

Fantin A, Herzog B, Mahmoud M, Yamaji M, Plein A, Denti L, Ruhrberg C, Zachary I.

Development. 2014 Feb;141(3):556-62. doi: 10.1242/dev.103028. Epub 2014 Jan 8.

PMID:
24401374
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Neuropilins: role in signalling, angiogenesis and disease.

Zachary I.

Chem Immunol Allergy. 2014;99:37-70. doi: 10.1159/000354169. Epub 2013 Oct 17. Review.

PMID:
24217602
[PubMed - indexed for MEDLINE]
10.

Production of soluble human vascular endothelial growth factor VEGF-A165-heparin binding domain in Escherichia coli.

Seyedarabi A, Cheng L, Zachary I, Djordjevic S.

PLoS One. 2013;8(2):e55690. doi: 10.1371/journal.pone.0055690. Epub 2013 Feb 8.

PMID:
23409021
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

p130Cas: a key signalling node in health and disease.

Barrett A, Pellet-Many C, Zachary IC, Evans IM, Frankel P.

Cell Signal. 2013 Apr;25(4):766-77. doi: 10.1016/j.cellsig.2012.12.019. Epub 2012 Dec 29. Review.

PMID:
23277200
[PubMed - indexed for MEDLINE]
12.

A heat-shock protein axis regulates VEGFR2 proteolysis, blood vessel development and repair.

Bruns AF, Yuldasheva N, Latham AM, Bao L, Pellet-Many C, Frankel P, Stephen SL, Howell GJ, Wheatcroft SB, Kearney MT, Zachary IC, Ponnambalam S.

PLoS One. 2012;7(11):e48539. doi: 10.1371/journal.pone.0048539. Epub 2012 Nov 6.

PMID:
23139789
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

How neuropilin-1 regulates receptor tyrosine kinase signalling: the knowns and known unknowns.

Zachary IC.

Biochem Soc Trans. 2011 Dec;39(6):1583-91. doi: 10.1042/BST20110697. Review.

PMID:
22103491
[PubMed - indexed for MEDLINE]
14.

Long-term increase in uterine blood flow is achieved by local overexpression of VEGF-A(165) in the uterine arteries of pregnant sheep.

Mehta V, Abi-Nader KN, Peebles DM, Benjamin E, Wigley V, Torondel B, Filippi E, Shaw SW, Boyd M, Martin J, Zachary I, David AL.

Gene Ther. 2012 Sep;19(9):925-35. doi: 10.1038/gt.2011.158. Epub 2011 Oct 20.

PMID:
22011641
[PubMed - indexed for MEDLINE]
15.

VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation.

Herzog B, Pellet-Many C, Britton G, Hartzoulakis B, Zachary IC.

Mol Biol Cell. 2011 Aug 1;22(15):2766-76. doi: 10.1091/mbc.E09-12-1061. Epub 2011 Jun 8.

PMID:
21653826
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Protein kinase D in vascular biology and angiogenesis.

Evans IM, Zachary IC.

IUBMB Life. 2011 Apr;63(4):258-63. doi: 10.1002/iub.456. Review.

PMID:
21488147
[PubMed - indexed for MEDLINE]
17.

Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas.

Pellet-Many C, Frankel P, Evans IM, Herzog B, Jünemann-Ramírez M, Zachary IC.

Biochem J. 2011 May 1;435(3):609-18. doi: 10.1042/BJ20100580.

PMID:
21306301
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells.

Evans IM, Yamaji M, Britton G, Pellet-Many C, Lockie C, Zachary IC, Frankel P.

Mol Cell Biol. 2011 Mar;31(6):1174-85. doi: 10.1128/MCB.00903-10. Epub 2011 Jan 18.

PMID:
21245381
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Therapeutic angiogenesis for cardiovascular disease: biological context, challenges, prospects.

Zachary I, Morgan RD.

Heart. 2011 Feb;97(3):181-9. doi: 10.1136/hrt.2009.180414. Epub 2010 Sep 30. Review.

PMID:
20884790
[PubMed - indexed for MEDLINE]
20.

Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells.

Evans IM, Bagherzadeh A, Charles M, Raynham T, Ireson C, Boakes A, Kelland L, Zachary IC.

Biochem J. 2010 Aug 1;429(3):565-72. doi: 10.1042/BJ20100578.

PMID:
20497126
[PubMed - indexed for MEDLINE]
Free PMC Article

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