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Items: 1 to 20 of 124


Imatinib and Nilotinib increase glioblastoma cell invasion via Abl-independent stimulation of p130Cas and FAK signalling.

Frolov A, Evans IM, Li N, Sidlauskas K, Paliashvili K, Lockwood N, Barrett A, Brandner S, Zachary IC, Frankel P.

Sci Rep. 2016 Jun 13;6:27378. doi: 10.1038/srep27378.


Peri- and Postnatal Effects of Prenatal Adenoviral VEGF Gene Therapy in Growth-Restricted Sheep.

Carr DJ, Wallace JM, Aitken RP, Milne JS, Martin JF, Zachary IC, Peebles DM, David AL.

Biol Reprod. 2016 Apr 20. pii: biolreprod.115.133744. [Epub ahead of print]


VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis.

Fearnley GW, Smith GA, Abdul-Zani I, Yuldasheva N, Mughal NA, Homer-Vanniasinkam S, Kearney MT, Zachary IC, Tomlinson DC, Harrison MA, Wheatcroft SB, Ponnambalam S.

Biol Open. 2016 May 15;5(5):571-83. doi: 10.1242/bio.017434.


Structural studies of neuropilin-2 reveal a zinc ion binding site remote from the vascular endothelial growth factor binding pocket.

Tsai YC, Fotinou C, Rana R, Yelland T, Frankel P, Zachary I, Djordjevic S.

FEBS J. 2016 May;283(10):1921-34. doi: 10.1111/febs.13711. Epub 2016 Apr 1.


Perspectives of HIV agencies on improving HIV prevention, treatment, and care services in the USA.

Khosla N, Zachary I.

AIDS Care. 2016 Feb 10:1-6. [Epub ahead of print]


Gene Targeting to the Uteroplacental Circulation of Pregnant Guinea Pigs.

Mehta V, Ofir K, Swanson A, Kloczko E, Boyd M, Barker H, Avdic-Belltheus A, Martin J, Zachary I, Peebles D, David AL.

Reprod Sci. 2016 Feb 10. pii: 1933719116630411. [Epub ahead of print]


Ablation of Neuropilin 1 from glioma-associated microglia and macrophages slows tumor progression.

Miyauchi JT, Chen D, Choi M, Nissen JC, Shroyer KR, Djordevic S, Zachary IC, Selwood D, Tsirka SE.

Oncotarget. 2016 Mar 1;7(9):9801-14. doi: 10.18632/oncotarget.6877.


Neuropilins 1 and 2 mediate neointimal hyperplasia and re-endothelialization following arterial injury.

Pellet-Many C, Mehta V, Fields L, Mahmoud M, Lowe V, Evans I, Ruivo J, Zachary I.

Cardiovasc Res. 2015 Nov 1;108(2):288-98. doi: 10.1093/cvr/cvv229. Epub 2015 Sep 25.


Information Management in Cancer Registries: Evaluating the Needs for Cancer Data Collection and Cancer Research.

Zachary I, Boren SA, Simoes E, Jackson-Thompson J, Davis JW, Hicks L.

Online J Public Health Inform. 2015 Jul 1;7(2):e213. doi: 10.5210/ojphi.v7i2.5664. eCollection 2015.


NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells.

Fantin A, Lampropoulou A, Gestri G, Raimondi C, Senatore V, Zachary I, Ruhrberg C.

Cell Rep. 2015 Jun 16;11(10):1577-90. doi: 10.1016/j.celrep.2015.05.018. Epub 2015 Jun 4. Erratum in: Cell Rep. 2015 Dec 1;13(9):2037.


Neuropilin 1 is essential for gastrointestinal smooth muscle contractility and motility in aged mice.

Yamaji M, Mahmoud M, Evans IM, Zachary IC.

PLoS One. 2015 Feb 6;10(2):e0115563. doi: 10.1371/journal.pone.0115563. eCollection 2015.


Local over-expression of VEGF-DΔNΔC in the uterine arteries of pregnant sheep results in long-term changes in uterine artery contractility and angiogenesis.

Mehta V, Abi-Nader KN, Shangaris P, Shaw SW, Filippi E, Benjamin E, Boyd M, Peebles DM, Martin J, Zachary I, David AL.

PLoS One. 2014 Jun 30;9(6):e100021. doi: 10.1371/journal.pone.0100021. eCollection 2014.


VEGF-A isoforms differentially regulate ATF-2-dependent VCAM-1 gene expression and endothelial-leukocyte interactions.

Fearnley GW, Odell AF, Latham AM, Mughal NA, Bruns AF, Burgoyne NJ, Homer-Vanniasinkam S, Zachary IC, Hollstein MC, Wheatcroft SB, Ponnambalam S.

Mol Biol Cell. 2014 Aug 15;25(16):2509-21. doi: 10.1091/mbc.E14-05-0962. Epub 2014 Jun 25.


Endosome-to-Plasma Membrane Recycling of VEGFR2 Receptor Tyrosine Kinase Regulates Endothelial Function and Blood Vessel Formation.

Jopling HM, Odell AF, Pellet-Many C, Latham AM, Frankel P, Sivaprasadarao A, Walker JH, Zachary IC, Ponnambalam S.

Cells. 2014 Apr 29;3(2):363-85. doi: 10.3390/cells3020363.


N-terminal modification of VEGF-A C terminus-derived peptides delineates structural features involved in neuropilin-1 binding and functional activity.

Jia H, Aqil R, Cheng L, Chapman C, Shaikh S, Jarvis A, Chan AW, Hartzoulakis B, Evans IM, Frolov A, Martin J, Frankel P, Djordevic S, Zachary IC, Selwood DL.

Chembiochem. 2014 May 26;15(8):1161-70. doi: 10.1002/cbic.201300658. Epub 2014 Apr 25.


A crucial role for DOK1 in PDGF-BB-stimulated glioma cell invasion through p130Cas and Rap1 signalling.

Barrett A, Evans IM, Frolov A, Britton G, Pellet-Many C, Yamaji M, Mehta V, Bandopadhyay R, Li N, Brandner S, Zachary IC, Frankel P.

J Cell Sci. 2014 Jun 15;127(Pt 12):2647-58. doi: 10.1242/jcs.135988. Epub 2014 Apr 24. Erratum in: J Cell Sci. 2014 Aug 1;127(Pt 15):3397.


Uteroplacental adenovirus vascular endothelial growth factor gene therapy increases fetal growth velocity in growth-restricted sheep pregnancies.

Carr DJ, Wallace JM, Aitken RP, Milne JS, Mehta V, Martin JF, Zachary IC, Peebles DM, David AL.

Hum Gene Ther. 2014 Apr;25(4):375-84. doi: 10.1089/hum.2013.214. Epub 2014 Apr 7.


Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis.

Fantin A, Herzog B, Mahmoud M, Yamaji M, Plein A, Denti L, Ruhrberg C, Zachary I.

Development. 2014 Feb;141(3):556-62. doi: 10.1242/dev.103028. Epub 2014 Jan 8.


Neuropilins: role in signalling, angiogenesis and disease.

Zachary I.

Chem Immunol Allergy. 2014;99:37-70. doi: 10.1159/000354169. Epub 2013 Oct 17. Review.


Production of soluble human vascular endothelial growth factor VEGF-A165-heparin binding domain in Escherichia coli.

Seyedarabi A, Cheng L, Zachary I, Djordjevic S.

PLoS One. 2013;8(2):e55690. doi: 10.1371/journal.pone.0055690. Epub 2013 Feb 8.

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