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Quantitative two-photon imaging of fluorescent biosensors.

Yellen G, Mongeon R.

Curr Opin Chem Biol. 2015 Jun 12;27:24-30. doi: 10.1016/j.cbpa.2015.05.024. [Epub ahead of print] Review.


The inward rectifier potassium channel Kir2.1 is expressed in mouse neutrophils from bone marrow and liver.

Masia R, Krause DS, Yellen G.

Am J Physiol Cell Physiol. 2015 Feb 1;308(3):C264-76. doi: 10.1152/ajpcell.00176.2014. Epub 2014 Dec 3.


Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels.

Lutas A, Birnbaumer L, Yellen G.

J Neurosci. 2014 Dec 3;34(49):16336-47. doi: 10.1523/JNEUROSCI.1357-14.2014.


Imaging changes in the cytosolic ATP-to-ADP ratio.

Tantama M, Yellen G.

Methods Enzymol. 2014;547:355-71. doi: 10.1016/B978-0-12-801415-8.00017-5.


Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step.

Shestov AA, Liu X, Ser Z, Cluntun AA, Hung YP, Huang L, Kim D, Le A, Yellen G, Albeck JG, Locasale JW.

Elife. 2014 Jul 9;3. doi: 10.7554/eLife.03342.


A PKA activity sensor for quantitative analysis of endogenous GPCR signaling via 2-photon FRET-FLIM imaging.

Chen Y, Saulnier JL, Yellen G, Sabatini BL.

Front Pharmacol. 2014 Apr 2;5:56. doi: 10.3389/fphar.2014.00056. eCollection 2014.


Imaging energy status in live cells with a fluorescent biosensor of the intracellular ATP-to-ADP ratio.

Tantama M, Martínez-François JR, Mongeon R, Yellen G.

Nat Commun. 2013;4:2550. doi: 10.1038/ncomms3550.


Live-cell imaging of cytosolic NADH-NAD+ redox state using a genetically encoded fluorescent biosensor.

Hung YP, Yellen G.

Methods Mol Biol. 2014;1071:83-95. doi: 10.1007/978-1-62703-622-1_7.


The ketogenic diet: metabolic influences on brain excitability and epilepsy.

Lutas A, Yellen G.

Trends Neurosci. 2013 Jan;36(1):32-40. doi: 10.1016/j.tins.2012.11.005. Epub 2012 Dec 8. Review.


Charge movement in gating-locked HCN channels reveals weak coupling of voltage sensors and gate.

Ryu S, Yellen G.

J Gen Physiol. 2012 Nov;140(5):469-79. doi: 10.1085/jgp.201210850. Epub 2012 Oct 15.


Structural changes during HCN channel gating defined by high affinity metal bridges.

Kwan DC, Prole DL, Yellen G.

J Gen Physiol. 2012 Sep;140(3):279-91. doi: 10.1085/jgp.201210838.


BAD-dependent regulation of fuel metabolism and K(ATP) channel activity confers resistance to epileptic seizures.

Giménez-Cassina A, Martínez-François JR, Fisher JK, Szlyk B, Polak K, Wiwczar J, Tanner GR, Lutas A, Yellen G, Danial NN.

Neuron. 2012 May 24;74(4):719-30. doi: 10.1016/j.neuron.2012.03.032.


Optogenetic reporters: Fluorescent protein-based genetically encoded indicators of signaling and metabolism in the brain.

Tantama M, Hung YP, Yellen G.

Prog Brain Res. 2012;196:235-63. doi: 10.1016/B978-0-444-59426-6.00012-4. Review.


Imaging cytosolic NADH-NAD(+) redox state with a genetically encoded fluorescent biosensor.

Hung YP, Albeck JG, Tantama M, Yellen G.

Cell Metab. 2011 Oct 5;14(4):545-54. doi: 10.1016/j.cmet.2011.08.012.


Single K ATP channel opening in response to action potential firing in mouse dentate granule neurons.

Tanner GR, Lutas A, Martínez-François JR, Yellen G.

J Neurosci. 2011 Jun 8;31(23):8689-96. doi: 10.1523/JNEUROSCI.5951-10.2011.


Imaging intracellular pH in live cells with a genetically encoded red fluorescent protein sensor.

Tantama M, Hung YP, Yellen G.

J Am Chem Soc. 2011 Jul 6;133(26):10034-7. doi: 10.1021/ja202902d. Epub 2011 Jun 9.


A genetically encoded fluorescent reporter of ATP:ADP ratio.

Berg J, Hung YP, Yellen G.

Nat Methods. 2009 Feb;6(2):161-6. doi: 10.1038/nmeth.1288. Epub 2009 Jan 4.


Ketone bodies, glycolysis, and KATP channels in the mechanism of the ketogenic diet.

Yellen G.

Epilepsia. 2008 Nov;49 Suppl 8:80-2. doi: 10.1111/j.1528-1167.2008.01843.x. Review.


Ketogenic diet metabolites reduce firing in central neurons by opening K(ATP) channels.

Ma W, Berg J, Yellen G.

J Neurosci. 2007 Apr 4;27(14):3618-25.


Cooperative gating between single HCN pacemaker channels.

Dekker JP, Yellen G.

J Gen Physiol. 2006 Nov;128(5):561-7. Epub 2006 Oct 16.

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