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Results: 1 to 20 of 27

1.

Histone Demethylase Jumonji AT-rich Interactive Domain 1B (JARID1B) Controls Mammary Gland Development by Regulating Key Developmental and Lineage Specification Genes.

Zou MR, Cao J, Liu Z, Huh SJ, Polyak K, Yan Q.

J Biol Chem. 2014 Jun 20;289(25):17620-33. doi: 10.1074/jbc.M114.570853. Epub 2014 May 6.

PMID:
24802759
[PubMed - in process]
2.

Jmjd3-mediated epigenetic regulation of inflammatory cytokine gene expression in serum amyloid A-stimulated macrophages.

Yan Q, Sun L, Zhu Z, Wang L, Li S, Ye RD.

Cell Signal. 2014 Sep;26(9):1783-91. doi: 10.1016/j.cellsig.2014.03.025. Epub 2014 Apr 1.

PMID:
24703936
[PubMed - in process]
3.

Histone demethylase RBP2 is critical for breast cancer progression and metastasis.

Cao J, Liu Z, Cheung WK, Zhao M, Chen SY, Chan SW, Booth CJ, Nguyen DX, Yan Q.

Cell Rep. 2014 Mar 13;6(5):868-77. doi: 10.1016/j.celrep.2014.02.004. Epub 2014 Feb 27.

PMID:
24582965
[PubMed - in process]
Free Article
4.

Histone demethylase RBP2 promotes lung tumorigenesis and cancer metastasis.

Teng YC, Lee CF, Li YS, Chen YR, Hsiao PW, Chan MY, Lin FM, Huang HD, Chen YT, Jeng YM, Hsu CH, Yan Q, Tsai MD, Juan LJ.

Cancer Res. 2013 Aug 1;73(15):4711-21. doi: 10.1158/0008-5472.CAN-12-3165. Epub 2013 May 30.

PMID:
23722541
[PubMed - indexed for MEDLINE]
5.

Histone demethylases set the stage for cancer metastasis.

Cao J, Yan Q.

Sci Signal. 2013 Apr 30;6(273):pe15, 1-2. doi: 10.1126/scisignal.2004188. Review.

PMID:
23633674
[PubMed - indexed for MEDLINE]
6.

Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.

Sayegh J, Cao J, Zou MR, Morales A, Blair LP, Norcia M, Hoyer D, Tackett AJ, Merkel JS, Yan Q.

J Biol Chem. 2013 Mar 29;288(13):9408-17. doi: 10.1074/jbc.M112.419861. Epub 2013 Feb 13.

PMID:
23408432
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation.

Beshiri ML, Holmes KB, Richter WF, Hess S, Islam AB, Yan Q, Plante L, Litovchick L, GĂ©vry N, Lopez-Bigas N, Kaelin WG Jr, Benevolenskaya EV.

Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18499-504. doi: 10.1073/pnas.1216724109. Epub 2012 Oct 23.

PMID:
23093672
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Histone ubiquitination and deubiquitination in transcription, DNA damage response, and cancer.

Cao J, Yan Q.

Front Oncol. 2012 Mar 12;2:26. doi: 10.3389/fonc.2012.00026. eCollection 2012.

PMID:
22649782
[PubMed]
Free PMC Article
9.

Epigenetic mechanisms in commonly occurring cancers.

Blair LP, Yan Q.

DNA Cell Biol. 2012 Oct;31 Suppl 1:S49-61. doi: 10.1089/dna.2012.1654. Epub 2012 Apr 20. Review.

PMID:
22519822
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1.

Lin W, Cao J, Liu J, Beshiri ML, Fujiwara Y, Francis J, Cherniack AD, Geisen C, Blair LP, Zou MR, Shen X, Kawamori D, Liu Z, Grisanzio C, Watanabe H, Minamishima YA, Zhang Q, Kulkarni RN, Signoretti S, Rodig SJ, Bronson RT, Orkin SH, Tuck DP, Benevolenskaya EV, Meyerson M, Kaelin WG Jr, Yan Q.

Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13379-86. doi: 10.1073/pnas.1110104108. Epub 2011 Jul 25.

PMID:
21788502
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C.

Niu X, Zhang T, Liao L, Zhou L, Lindner DJ, Zhou M, Rini B, Yan Q, Yang H.

Oncogene. 2012 Feb 9;31(6):776-86. doi: 10.1038/onc.2011.266. Epub 2011 Jul 4.

PMID:
21725364
[PubMed - indexed for MEDLINE]
12.

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.

Blair LP, Cao J, Zou MR, Sayegh J, Yan Q.

Cancers (Basel). 2011 Mar 1;3(1):1383-404. doi: 10.3390/cancers3011383.

PMID:
21544224
[PubMed]
Free PMC Article
13.

Exploiting cellular senescence to treat cancer and circumvent drug resistance.

Yan Q, Wajapeyee N.

Cancer Biol Ther. 2010 Feb;9(3):166-75. Epub 2010 Feb 11. Review.

PMID:
20118655
[PubMed - indexed for MEDLINE]
Free Article
14.

A role for mammalian Sin3 in permanent gene silencing.

van Oevelen C, Wang J, Asp P, Yan Q, Kaelin WG Jr, Kluger Y, Dynlacht BD.

Mol Cell. 2008 Nov 7;32(3):359-70. doi: 10.1016/j.molcel.2008.10.015.

PMID:
18995834
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-kappaB agonist Card9 by CK2.

Yang H, Minamishima YA, Yan Q, Schlisio S, Ebert BL, Zhang X, Zhang L, Kim WY, Olumi AF, Kaelin WG Jr.

Mol Cell. 2007 Oct 12;28(1):15-27.

PMID:
17936701
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations.

Li L, Zhang L, Zhang X, Yan Q, Minamishima YA, Olumi AF, Mao M, Bartz S, Kaelin WG Jr.

Mol Cell Biol. 2007 Aug;27(15):5381-92. Epub 2007 May 25.

PMID:
17526729
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The retinoblastoma binding protein RBP2 is an H3K4 demethylase.

Klose RJ, Yan Q, Tothova Z, Yamane K, Erdjument-Bromage H, Tempst P, Gilliland DG, Zhang Y, Kaelin WG Jr.

Cell. 2007 Mar 9;128(5):889-900. Epub 2007 Feb 22.

PMID:
17320163
[PubMed - indexed for MEDLINE]
Free Article
18.

The hypoxia-inducible factor 2alpha N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo.

Yan Q, Bartz S, Mao M, Li L, Kaelin WG Jr.

Mol Cell Biol. 2007 Mar;27(6):2092-102. Epub 2007 Jan 12.

PMID:
17220275
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53.

Blanchette P, Cheng CY, Yan Q, Ketner G, Ornelles DA, Dobner T, Conaway RC, Conaway JW, Branton PE.

Mol Cell Biol. 2004 Nov;24(21):9619-29.

PMID:
15485928
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Identification of Elongin C and Skp1 sequences that determine Cullin selection.

Yan Q, Kamura T, Cai Y, Jin J, Ivan M, Mushegian A, Conaway RC, Conaway JW.

J Biol Chem. 2004 Oct 8;279(41):43019-26. Epub 2004 Jul 27.

PMID:
15280393
[PubMed - indexed for MEDLINE]
Free Article

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