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Items: 1 to 20 of 212

1.

Protein Regulation in Signal Transduction.

Lee MJ, Yaffe MB.

Cold Spring Harb Perspect Biol. 2016 Jun 1;8(6). pii: a005918. doi: 10.1101/cshperspect.a005918. Review.

PMID:
27252361
2.

Kicking Genomic Profiling to the Curb: How Re-wiring the Phosphoproteome Can Explain Treatment Resistance in Glioma.

Lam FC, Yaffe MB.

Cancer Cell. 2016 Apr 11;29(4):435-6. doi: 10.1016/j.ccell.2016.03.022.

PMID:
27070697
3.

Leveraging signaling research to understand and treat disease.

Yaffe MB, Gough NR.

Sci Signal. 2016 Mar 29;9(421):eg4. doi: 10.1126/scisignal.aaf6275.

PMID:
27025875
4.

A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy.

Cannell IG, Merrick KA, Morandell S, Zhu CQ, Braun CJ, Grant RA, Cameron ER, Tsao MS, Hemann MT, Yaffe MB.

Cancer Cell. 2015 Nov 9;28(5):623-37. Erratum in: Cancer Cell. 2015 Dec 14;28(6):831.

PMID:
26602816
5.

Neighbor-directed histidine N (τ)-alkylation: A route to imidazolium-containing phosphopeptide macrocycles.

Qian WJ, Park JE, Grant R, Lai CC, Kelley JA, Yaffe MB, Lee KS, Burke TR Jr.

Biopolymers. 2015 Nov;104(6):663-73. doi: 10.1002/bip.22698.

PMID:
26152807
6.

Tumor-Targeted Synergistic Blockade of MAPK and PI3K from a Layer-by-Layer Nanoparticle.

Dreaden EC, Kong YW, Morton SW, Correa S, Choi KY, Shopsowitz KE, Renggli K, Drapkin R, Yaffe MB, Hammond PT.

Clin Cancer Res. 2015 Oct 1;21(19):4410-9. doi: 10.1158/1078-0432.CCR-15-0013. Epub 2015 Jun 1.

PMID:
26034127
7.

Kinetics and Role of Plasma Matrix Metalloproteinase-9 Expression in Acute Lung Injury and the Acute Respiratory Distress Syndrome.

Hsu AT, Barrett CD, DeBusk GM, Ellson CD, Gautam S, Talmor DS, Gallagher DC, Yaffe MB.

Shock. 2015 Aug;44(2):128-36. doi: 10.1097/SHK.0000000000000386.

PMID:
26009816
8.

A Multivariate Computational Method to Analyze High-Content RNAi Screening Data.

Rameseder J, Krismer K, Dayma Y, Ehrenberger T, Hwang MK, Airoldi EM, Floyd SR, Yaffe MB.

J Biomol Screen. 2015 Sep;20(8):985-97. doi: 10.1177/1087057115583037. Epub 2015 Apr 27.

PMID:
25918037
9.

Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2.

Zhu EF, Gai SA, Opel CF, Kwan BH, Surana R, Mihm MC, Kauke MJ, Moynihan KD, Angelini A, Williams RT, Stephan MT, Kim JS, Yaffe MB, Irvine DJ, Weiner LM, Dranoff G, Wittrup KD.

Cancer Cell. 2015 Apr 13;27(4):489-501. doi: 10.1016/j.ccell.2015.03.004.

10.

Computational prediction of protein-protein interactions.

Ehrenberger T, Cantley LC, Yaffe MB.

Methods Mol Biol. 2015;1278:57-75. doi: 10.1007/978-1-4939-2425-7_4.

11.

Criteria for biological reproducibility: what does "n" mean?

Naegle K, Gough NR, Yaffe MB.

Sci Signal. 2015 Apr 7;8(371):fs7. doi: 10.1126/scisignal.aab1125. Review.

PMID:
25852186
12.

Reproducibility in science.

Yaffe MB.

Sci Signal. 2015 Apr 7;8(371):eg5. doi: 10.1126/scisignal.aaa5764.

PMID:
25852185
13.

Engineered bromodomains to explore the acetylproteome.

Bryson BD, Del Rosario AM, Gootenberg JS, Yaffe MB, White FM.

Proteomics. 2015 May;15(9):1470-5. doi: 10.1002/pmic.201400401. Epub 2015 Mar 5.

14.

Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation.

Lunt SY, Muralidhar V, Hosios AM, Israelsen WJ, Gui DY, Newhouse L, Ogrodzinski M, Hecht V, Xu K, Acevedo PN, Hollern DP, Bellinger G, Dayton TL, Christen S, Elia I, Dinh AT, Stephanopoulos G, Manalis SR, Yaffe MB, Andrechek ER, Fendt SM, Vander Heiden MG.

Mol Cell. 2015 Jan 8;57(1):95-107. doi: 10.1016/j.molcel.2014.10.027. Epub 2014 Dec 4.

15.

The initial response to the Boston marathon bombing: lessons learned to prepare for the next disaster.

Gates JD, Arabian S, Biddinger P, Blansfield J, Burke P, Chung S, Fischer J, Friedman F, Gervasini A, Goralnick E, Gupta A, Larentzakis A, McMahon M, Mella J, Michaud Y, Mooney D, Rabinovici R, Sweet D, Ulrich A, Velmahos G, Weber C, Yaffe MB.

Ann Surg. 2014 Dec;260(6):960-6. doi: 10.1097/SLA.0000000000000914.

PMID:
25386862
16.

Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high Plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in HeLa cells.

Qian WJ, Park JE, Lim D, Lai CC, Kelley JA, Park SY, Lee KW, Yaffe MB, Lee KS, Burke TR Jr.

Biopolymers. 2014 Nov;102(6):444-55. doi: 10.1002/bip.22569.

17.

Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition.

Shaul YD, Freinkman E, Comb WC, Cantor JR, Tam WL, Thiru P, Kim D, Kanarek N, Pacold ME, Chen WW, Bierie B, Possemato R, Reinhardt F, Weinberg RA, Yaffe MB, Sabatini DM.

Cell. 2014 Aug 28;158(5):1094-109. doi: 10.1016/j.cell.2014.07.032.

18.

Selective mitogen activated protein kinase activity sensors through the application of directionally programmable D domain motifs.

Peterson LB, Yaffe MB, Imperiali B.

Biochemistry. 2014 Sep 16;53(36):5771-8. doi: 10.1021/bi500862c. Epub 2014 Sep 3.

19.

Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor.

Lu G, Zhang Q, Huang Y, Song J, Tomaino R, Ehrenberger T, Lim E, Liu W, Bronson RT, Bowden M, Brock J, Krop IE, Dillon DA, Gygi SP, Mills GB, Richardson AL, Signoretti S, Yaffe MB, Kaelin WG Jr.

Cancer Cell. 2014 Aug 11;26(2):222-34. doi: 10.1016/j.ccr.2014.06.026.

20.

A nanoparticle-based combination chemotherapy delivery system for enhanced tumor killing by dynamic rewiring of signaling pathways.

Morton SW, Lee MJ, Deng ZJ, Dreaden EC, Siouve E, Shopsowitz KE, Shah NJ, Yaffe MB, Hammond PT.

Sci Signal. 2014 May 13;7(325):ra44. doi: 10.1126/scisignal.2005261.

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