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Results: 1 to 20 of 163

1.

Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature.

Haberman Y, Tickle TL, Dexheimer PJ, Kim MO, Tang D, Karns R, Baldassano RN, Noe JD, Rosh J, Markowitz J, Heyman MB, Griffiths AM, Crandall WV, Mack DR, Baker SS, Huttenhower C, Keljo DJ, Hyams JS, Kugathasan S, Walters TD, Aronow B, Xavier RJ, Gevers D, Denson LA.

J Clin Invest. 2014 Jul 8. pii: 75436. doi: 10.1172/JCI75436. [Epub ahead of print]

PMID:
25003194
[PubMed - as supplied by publisher]
2.

Helminth infection reactivates latent γ-herpesvirus via cytokine competition at a viral promoter.

Reese TA, Wakeman BS, Choi HS, Hufford MM, Huang SC, Zhang X, Buck MD, Jezewski A, Kambal A, Liu CY, Goel G, Murray PJ, Xavier RJ, Kaplan MH, Renne R, Speck SH, Artyomov MN, Pearce EJ, Virgin HW.

Science. 2014 Jun 26. pii: 1254517. [Epub ahead of print]

PMID:
24968940
[PubMed - as supplied by publisher]
3.

Inflammatory Bowel Disease as a Model for Translating the Microbiome.

Huttenhower C, Kostic AD, Xavier RJ.

Immunity. 2014 Jun 19;40(6):843-854. doi: 10.1016/j.immuni.2014.05.013. Review.

PMID:
24950204
[PubMed - as supplied by publisher]
4.

SLCO3A1, a Novel Crohn's Disease-Associated Gene, Regulates NF-κB Activity and Associates with Intestinal Perforation.

Wei SC, Tan YY, Weng MT, Lai LC, Hsiao JH, Chuang EY, Shun CT, Wu DC, Kao AW, Chuang CS, Ni YH, Shieh MJ, Tung CC, Chen Y, Wang CY, Xavier RJ, Podolsky DK, Wong JM.

PLoS One. 2014 Jun 19;9(6):e100515. doi: 10.1371/journal.pone.0100515. eCollection 2014.

PMID:
24945726
[PubMed - in process]
Free PMC Article
5.

Dectin-1-Dependent LC3 Recruitment to Phagosomes Enhances Fungicidal Activity in Macrophages.

Tam JM, Mansour MK, Khan NS, Seward M, Puranam S, Tanne A, Sokolovska A, Becker CE, Acharya M, Baird MA, Choi AM, Davidson MW, Segal BH, Lacy-Hulbert A, Stuart LM, Xavier RJ, Vyas JM.

J Infect Dis. 2014 May 19. pii: jiu290. [Epub ahead of print]

PMID:
24842831
[PubMed - as supplied by publisher]
6.

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense.

Lassen KG, Kuballa P, Conway KL, Patel KK, Becker CE, Peloquin JM, Villablanca EJ, Norman JM, Liu TC, Heath RJ, Becker ML, Fagbami L, Horn H, Mercer J, Yilmaz OH, Jaffe JD, Shamji AF, Bhan AK, Carr SA, Daly MJ, Virgin HW, Schreiber SL, Stappenbeck TS, Xavier RJ.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7741-6. doi: 10.1073/pnas.1407001111. Epub 2014 May 12.

PMID:
24821797
[PubMed - in process]
Free PMC Article
7.

Novel mechanism of tumor suppression by polarity gene discs large 1 (DLG1) revealed in a murine model of pediatric B-ALL.

Sandoval GJ, Graham DB, Gmyrek GB, Akilesh HM, Fujikawa K, Sammut B, Bhattacharya D, Srivatsan S, Kim A, Shaw AS, Yang-Iott K, Bassing CH, Duncavage E, Xavier RJ, Swat W.

Cancer Immunol Res. 2013 Dec;1(6):426-37. doi: 10.1158/2326-6066.CIR-13-0065. Epub 2013 Oct 7.

PMID:
24778134
[PubMed - in process]
8.

Quantum chemical computations, vibrational spectroscopic studies, NLO and NBO/NLMO analysis of o-chlorobenzohydrazide.

Gobinath E, Xavier RJ.

Spectrochim Acta A Mol Biomol Spectrosc. 2014 Aug 14;129:14-21. doi: 10.1016/j.saa.2014.03.026. Epub 2014 Mar 27.

PMID:
24727163
[PubMed - in process]
9.

Vibrational spectra, monomer, dimer, NBO, HOMO, LUMO and NMR analyses of trans-4-hydroxy-L-proline.

Xavier RJ, Dinesh P.

Spectrochim Acta A Mol Biomol Spectrosc. 2014 Jul 15;128:54-68. doi: 10.1016/j.saa.2014.02.047. Epub 2014 Mar 6.

PMID:
24657468
[PubMed - in process]
10.

Genetic polymorphisms in metabolizing enzymes modifying the association between smoking and inflammatory bowel diseases.

Ananthakrishnan AN, Nguyen DD, Sauk J, Yajnik V, Xavier RJ.

Inflamm Bowel Dis. 2014 May;20(5):783-9. doi: 10.1097/MIB.0000000000000014.

PMID:
24651583
[PubMed - in process]
11.

The treatment-naive microbiome in new-onset Crohn's disease.

Gevers D, Kugathasan S, Denson LA, Vázquez-Baeza Y, Van Treuren W, Ren B, Schwager E, Knights D, Song SJ, Yassour M, Morgan XC, Kostic AD, Luo C, González A, McDonald D, Haberman Y, Walters T, Baker S, Rosh J, Stephens M, Heyman M, Markowitz J, Baldassano R, Griffiths A, Sylvester F, Mack D, Kim S, Crandall W, Hyams J, Huttenhower C, Knight R, Xavier RJ.

Cell Host Microbe. 2014 Mar 12;15(3):382-92. doi: 10.1016/j.chom.2014.02.005.

PMID:
24629344
[PubMed - in process]
12.

Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response.

Pulloor NK, Nair S, Kostic AD, Bist P, Weaver JD, Riley AM, Tyagi R, Uchil PD, York JD, Snyder SH, García-Sastre A, Potter BV, Lin R, Shears SB, Xavier RJ, Krishnan MN.

PLoS Pathog. 2014 Feb 27;10(2):e1003981. doi: 10.1371/journal.ppat.1003981. eCollection 2014 Feb. Erratum in: PLoS Pathog. 2014 Mar;10(3):e1004095.

PMID:
24586175
[PubMed - in process]
Free PMC Article
13.

The microbiome in inflammatory bowel disease: current status and the future ahead.

Kostic AD, Xavier RJ, Gevers D.

Gastroenterology. 2014 May;146(6):1489-99. doi: 10.1053/j.gastro.2014.02.009. Epub 2014 Feb 19. Review.

PMID:
24560869
[PubMed - indexed for MEDLINE]
14.

IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans.

de Luca A, Smeekens SP, Casagrande A, Iannitti R, Conway KL, Gresnigt MS, Begun J, Plantinga TS, Joosten LA, van der Meer JW, Chamilos G, Netea MG, Xavier RJ, Dinarello CA, Romani L, van de Veerdonk FL.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3526-31. doi: 10.1073/pnas.1322831111. Epub 2014 Feb 18.

PMID:
24550444
[PubMed - indexed for MEDLINE]
15.

SMAD3 gene variant is a risk factor for recurrent surgery in patients with Crohn's disease.

Fowler SA, Ananthakrishnan AN, Gardet A, Stevens CR, Korzenik JR, Sands BE, Daly MJ, Xavier RJ, Yajnik V.

J Crohns Colitis. 2014 Aug 1;8(8):845-51. doi: 10.1016/j.crohns.2014.01.003. Epub 2014 Jan 24.

PMID:
24461721
[PubMed - in process]
16.

Autophagy is essential for cardiac morphogenesis during vertebrate development.

Lee E, Koo Y, Ng A, Wei Y, Luby-Phelps K, Juraszek A, Xavier RJ, Cleaver O, Levine B, Amatruda JF.

Autophagy. 2014 Apr;10(4):572-87. doi: 10.4161/auto.27649. Epub 2014 Jan 14.

PMID:
24441423
[PubMed - in process]
17.

Differential effect of genetic burden on disease phenotypes in Crohn's disease and ulcerative colitis: analysis of a North American cohort.

Ananthakrishnan AN, Huang H, Nguyen DD, Sauk J, Yajnik V, Xavier RJ.

Am J Gastroenterol. 2014 Mar;109(3):395-400. doi: 10.1038/ajg.2013.464. Epub 2014 Jan 14.

PMID:
24419484
[PubMed - indexed for MEDLINE]
18.

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia.

Liu Y, Shoji-Kawata S, Sumpter RM Jr, Wei Y, Ginet V, Zhang L, Posner B, Tran KA, Green DR, Xavier RJ, Shaw SY, Clarke PG, Puyal J, Levine B.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20364-71. doi: 10.1073/pnas.1319661110. Epub 2013 Nov 25.

PMID:
24277826
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Autophagy is redundant for the host defense against systemic Candida albicans infections.

Smeekens SP, Malireddi RK, Plantinga TS, Buffen K, Oosting M, Joosten LA, Kullberg BJ, Perfect JR, Scott WK, van de Veerdonk FL, Xavier RJ, van de Vosse E, Kanneganti TD, Johnson MD, Netea MG.

Eur J Clin Microbiol Infect Dis. 2014 May;33(5):711-22. doi: 10.1007/s10096-013-2002-x. Epub 2013 Nov 8.

PMID:
24202731
[PubMed - in process]
20.

Long-lasting effects of BCG vaccination on both heterologous Th1/Th17 responses and innate trained immunity.

Kleinnijenhuis J, Quintin J, Preijers F, Benn CS, Joosten LA, Jacobs C, van Loenhout J, Xavier RJ, Aaby P, van der Meer JW, van Crevel R, Netea MG.

J Innate Immun. 2014;6(2):152-8. doi: 10.1159/000355628. Epub 2013 Oct 30.

PMID:
24192057
[PubMed - in process]

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