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Results: 1 to 20 of 194

1.

Hypothesis testing at the extremes: fast and robust association for high-throughput data.

Zhou YH, Wright FA.

Biostatistics. 2015 Mar 18. pii: kxv007. [Epub ahead of print]

PMID:
25792622
2.

An analysis of the therapeutic benefits of genotyping in pediatric hematopoietic stem cell transplantation.

Wright FA, Bebawy M, O'Brien TA.

Future Oncol. 2015 Mar;11(5):833-51. doi: 10.2217/fon.14.307.

PMID:
25757685
3.

Gene expression in transformed lymphocytes reveals variation in endomembrane and HLA pathways modifying cystic fibrosis pulmonary phenotypes.

O'Neal WK, Gallins P, Pace RG, Dang H, Wolf WE, Jones LC, Guo X, Zhou YH, Madar V, Huang J, Liang L, Moffatt MF, Cutting GR, Drumm ML, Rommens JM, Strug LJ, Sun W, Stonebraker JR, Wright FA, Knowles MR.

Am J Hum Genet. 2015 Feb 5;96(2):318-28. doi: 10.1016/j.ajhg.2014.12.022. Epub 2015 Jan 29.

PMID:
25640674
4.

Population-Based in Vitro Hazard and Concentration-Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study.

Abdo N, Xia M, Brown CC, Kosyk O, Huang R, Sakamuru S, Zhou YH, Jack J, Gallins P, Xia K, Li Y, Chiu WA, Motsinger-Reif A, Austin CP, Tice RR, Rusyn I, Wright FA.

Environ Health Perspect. 2015 Jan 13. [Epub ahead of print]

5.

Metabolomic evaluation of neutrophilic airway inflammation in cystic fibrosis.

Esther CR Jr, Coakley RD, Henderson AG, Zhou YH, Wright FA, Boucher RC.

Chest. 2015 Jan 22. doi: 10.1378/chest.14-1800. [Epub ahead of print]

PMID:
25611918
6.
7.

Heritability and genomics of gene expression in peripheral blood.

Wright FA, Sullivan PF, Brooks AI, Zou F, Sun W, Xia K, Madar V, Jansen R, Chung W, Zhou YH, Abdellaoui A, Batista S, Butler C, Chen G, Chen TH, D'Ambrosio D, Gallins P, Ha MJ, Hottenga JJ, Huang S, Kattenberg M, Kochar J, Middeldorp CM, Qu A, Shabalin A, Tischfield J, Todd L, Tzeng JY, van Grootheest G, Vink JM, Wang Q, Wang W, Wang W, Willemsen G, Smit JH, de Geus EJ, Yin Z, Penninx BW, Boomsma DI.

Nat Genet. 2014 May;46(5):430-7. doi: 10.1038/ng.2951. Epub 2014 Apr 13.

8.

Standardizing benchmark dose calculations to improve science-based decisions in human health assessments.

Wignall JA, Shapiro AJ, Wright FA, Woodruff TJ, Chiu WA, Guyton KZ, Rusyn I.

Environ Health Perspect. 2014 May;122(5):499-505. doi: 10.1289/ehp.1307539. Epub 2014 Feb 25.

9.

Physiologically based pharmacokinetic (PBPK) modeling of interstrain variability in trichloroethylene metabolism in the mouse.

Chiu WA, Campbell JL Jr, Clewell HJ 3rd, Zhou YH, Wright FA, Guyton KZ, Rusyn I.

Environ Health Perspect. 2014 May;122(5):456-63. doi: 10.1289/ehp.1307623. Epub 2014 Feb 11.

10.

Sex differences in the human peripheral blood transcriptome.

Jansen R, Batista S, Brooks AI, Tischfield JA, Willemsen G, van Grootheest G, Hottenga JJ, Milaneschi Y, Mbarek H, Madar V, Peyrot W, Vink JM, Verweij CL, de Geus EJ, Smit JH, Wright FA, Sullivan PF, Boomsma DI, Penninx BW.

BMC Genomics. 2014 Jan 17;15:33. doi: 10.1186/1471-2164-15-33.

11.

Unified Analysis of Secondary Traits in Case-Control Association Studies.

Ghosh A, Wright FA, Zou F.

J Am Stat Assoc. 2013;108(502). doi: 10.1080/01621459.2013.793121.

12.

Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs.

Sanders AP, Smeester L, Rojas D, DeBussycher T, Wu MC, Wright FA, Zhou YH, Laine JE, Rager JE, Swamy GK, Ashley-Koch A, Lynn Miranda M, Fry RC.

Epigenetics. 2014 Feb;9(2):212-21. doi: 10.4161/epi.26798. Epub 2013 Oct 28.

13.

Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicity.

Sirenko O, Cromwell EF, Crittenden C, Wignall JA, Wright FA, Rusyn I.

Toxicol Appl Pharmacol. 2013 Dec 15;273(3):500-7. doi: 10.1016/j.taap.2013.09.017. Epub 2013 Oct 1.

14.

Pharmacokinetic analysis of enoxaparin in a term neonate and review of literature.

Mateos MK, Wright FA, Cohn RJ.

Thromb Res. 2013 Oct;132(4):487-9. doi: 10.1016/j.thromres.2013.06.024. Epub 2013 Aug 29. No abstract available.

PMID:
23992876
15.

The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage.

Schulman JJ, Wright FA, Kaufmann T, Wojcikiewicz RJ.

J Biol Chem. 2013 Aug 30;288(35):25340-9. doi: 10.1074/jbc.M113.496570. Epub 2013 Jul 24.

16.

The value of statistical or bioinformatics annotation for rare variant association with quantitative trait.

Byrnes AE, Wu MC, Wright FA, Li M, Li Y.

Genet Epidemiol. 2013 Nov;37(7):666-74. doi: 10.1002/gepi.21747. Epub 2013 Jul 8.

17.

Genetic modifiers of cystic fibrosis-related diabetes.

Blackman SM, Commander CW, Watson C, Arcara KM, Strug LJ, Stonebraker JR, Wright FA, Rommens JM, Sun L, Pace RG, Norris SA, Durie PR, Drumm ML, Knowles MR, Cutting GR.

Diabetes. 2013 Oct;62(10):3627-35. doi: 10.2337/db13-0510. Epub 2013 May 13.

18.

Molecular subtypes in head and neck cancer exhibit distinct patterns of chromosomal gain and loss of canonical cancer genes.

Walter V, Yin X, Wilkerson MD, Cabanski CR, Zhao N, Du Y, Ang MK, Hayward MC, Salazar AH, Hoadley KA, Fritchie K, Sailey CJ, Weissler MC, Shockley WW, Zanation AM, Hackman T, Thorne LB, Funkhouser WD, Muldrew KL, Olshan AF, Randell SH, Wright FA, Shores CG, Hayes DN.

PLoS One. 2013;8(2):e56823. doi: 10.1371/journal.pone.0056823. Epub 2013 Feb 22. Erratum in: PLoS One. 2013;8(7). doi:10.1371/annotation/b42f61c5-cb7e-49ca-8cd6-6e1f7903ad08. Sailey, Charles G [corrected to Sailey, Charles J]. PLoS One. 2014;9(1). doi:10.1371/annotation/e9ad5950-a048-4a44-8e26-d8b07a9d4bb8.

19.

Empirical pathway analysis, without permutation.

Zhou YH, Barry WT, Wright FA.

Biostatistics. 2013 Jul;14(3):573-85. doi: 10.1093/biostatistics/kxt004. Epub 2013 Feb 20.

20.

Biomarkers of exposure and effect in human lymphoblastoid TK6 cells following [13C2]-acetaldehyde exposure.

Moeller BC, Recio L, Green A, Sun W, Wright FA, Bodnar WM, Swenberg JA.

Toxicol Sci. 2013 May;133(1):1-12. doi: 10.1093/toxsci/kft029. Epub 2013 Feb 19.

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