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Results: 1 to 20 of 33


Potential role of glutathione in evolution of thiol-based redox signaling sites in proteins.

Mohanasundaram KA, Haworth NL, Grover MP, Crowley TM, Goscinski A, Wouters MA.

Front Pharmacol. 2015 Mar 10;6:1. doi: 10.3389/fphar.2015.00001. eCollection 2015.


Identification of novel therapeutics for complex diseases from genome-wide association data.

Grover MP, Ballouz S, Mohanasundaram KA, George RA, Sherman CD, Crowley TM, Wouters MA.

BMC Med Genomics. 2014;7 Suppl 1:S8. doi: 10.1186/1755-8794-7-S1-S8. Epub 2014 May 8.


Candidate disease gene prediction using Gentrepid: application to a genome-wide association study on coronary artery disease.

Ballouz S, Liu JY, Oti M, Gaeta B, Fatkin D, Bahlo M, Wouters MA.

Mol Genet Genomic Med. 2014 Jan;2(1):44-57. doi: 10.1002/mgg3.40. Epub 2013 Nov 13.


Gentrepid V2.0: a web server for candidate disease gene prediction.

Ballouz S, Liu JY, George RA, Bains N, Liu A, Oti M, Gaeta B, Fatkin D, Wouters MA.

BMC Bioinformatics. 2013 Aug 16;14:249. doi: 10.1186/1471-2105-14-249.


Epistatic effects of potassium channel variation on cardiac repolarization and atrial fibrillation risk.

Mann SA, Otway R, Guo G, Soka M, Karlsdotter L, Trivedi G, Ohanian M, Zodgekar P, Smith RA, Wouters MA, Subbiah R, Walker B, Kuchar D, Sanders P, Griffiths L, Vandenberg JI, Fatkin D.

J Am Coll Cardiol. 2012 Mar 13;59(11):1017-25. doi: 10.1016/j.jacc.2011.11.039.


Analysis of genome-wide association study data using the protein knowledge base.

Ballouz S, Liu JY, Oti M, Gaeta B, Fatkin D, Bahlo M, Wouters MA.

BMC Genet. 2011 Nov 13;12:98. doi: 10.1186/1471-2156-12-98.


Web tools for the prioritization of candidate disease genes.

Oti M, Ballouz S, Wouters MA.

Methods Mol Biol. 2011;760:189-206. doi: 10.1007/978-1-61779-176-5_12.


Thiol-based redox signalling: rust never sleeps.

Wouters MA, Iismaa S, Fan SW, Haworth NL.

Int J Biochem Cell Biol. 2011 Aug;43(8):1079-85. doi: 10.1016/j.biocel.2011.04.002. Epub 2011 Apr 13. Review.


Cell cycle sensing of oxidative stress in Saccharomyces cerevisiae by oxidation of a specific cysteine residue in the transcription factor Swi6p.

Chiu J, Tactacan CM, Tan SX, Lin RC, Wouters MA, Dawes IW.

J Biol Chem. 2011 Feb 18;286(7):5204-14. doi: 10.1074/jbc.M110.172973. Epub 2010 Dec 8.


Two novel missense mutations in HAIRY-AND-ENHANCER-OF-SPLIT-7 in a family with spondylocostal dysostosis.

Sparrow DB, Sillence D, Wouters MA, Turnpenny PD, Dunwoodie SL.

Eur J Hum Genet. 2010 Jun;18(6):674-9. doi: 10.1038/ejhg.2009.241. Epub 2010 Jan 20.


Disulfides as redox switches: from molecular mechanisms to functional significance.

Wouters MA, Fan SW, Haworth NL.

Antioxid Redox Signal. 2010 Jan;12(1):53-91. doi: 10.1089/ARS.2009.2510. Review. Erratum in: Antioxid Redox Signal. 2010 Feb;12(2):321. Cortese-Krott,Miriam [removed]; Hanas,Jay [removed]; Kroencke Klaus [removed], Larabee, Jason [removed]; Lu,Hui [removed]; Outten, F. Wayne [removed]; Palumaa, Peep [removed].


Conformational changes in redox pairs of protein structures.

Fan SW, George RA, Haworth NL, Feng LL, Liu JY, Wouters MA.

Protein Sci. 2009 Aug;18(8):1745-65. doi: 10.1002/pro.175.


Structural and functional characterization of the oxidoreductase alpha-DsbA1 from Wolbachia pipientis.

Kurz M, Iturbe-Ormaetxe I, Jarrott R, Shouldice SR, Wouters MA, Frei P, Glockshuber R, O'Neill SL, Heras B, Martin JL.

Antioxid Redox Signal. 2009 Jul;11(7):1485-500. doi: 10.1089/ARS.2008.2420.


Comparison of automated candidate gene prediction systems using genes implicated in type 2 diabetes by genome-wide association studies.

Teber ET, Liu JY, Ballouz S, Fatkin D, Wouters MA.

BMC Bioinformatics. 2009 Jan 30;10 Suppl 1:S69. doi: 10.1186/1471-2105-10-S1-S69.


Response to Stenson et al on the review of general mutation databases.

George RA, Smith TD, Callaghan S, Hardman L, Pierides C, Horaitis O, Wouters MA, Cotton RG.

J Med Genet. 2008 May;45(5):319-20. No abstract available.


Identifying foldable regions in protein sequence from the hydrophobic signal.

Pang CN, Lin K, Wouters MA, Heringa J, George RA.

Nucleic Acids Res. 2008 Feb;36(2):578-88. Epub 2007 Dec 1.


"Forbidden" disulfides: their role as redox switches.

Wouters MA, George RA, Haworth NL.

Curr Protein Pept Sci. 2007 Oct;8(5):484-95. Review.


General mutation databases: analysis and review.

George RA, Smith TD, Callaghan S, Hardman L, Pierides C, Horaitis O, Wouters MA, Cotton RG.

J Med Genet. 2008 Feb;45(2):65-70. Epub 2007 Sep 24. Review.


Evaluating the stability of disulfide bridges in proteins: a torsional potential energy surface for diethyl disulfide.

Haworth NL, Gready JE, George RA, Wouters MA.

Mol Simul. 2007 May;33(6-8):475-485. Epub 2007 Aug 15.


Mechanism of allosteric regulation of transglutaminase 2 by GTP.

Begg GE, Carrington L, Stokes PH, Matthews JM, Wouters MA, Husain A, Lorand L, Iismaa SE, Graham RM.

Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19683-8. Epub 2006 Dec 18.

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