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Results: 1 to 20 of 79

1.

Altered expression of metabolic proteins and adipokines in patients with amyotrophic lateral sclerosis.

Ngo ST, Steyn FJ, Huang L, Mantovani S, Pfluger CM, Woodruff TM, O'Sullivan JD, Henderson RD, McCombe PA.

J Neurol Sci. 2015 Jul 6. pii: S0022-510X(15)00394-9. doi: 10.1016/j.jns.2015.06.053. [Epub ahead of print]

2.
3.

C5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosus.

Mahajan SD, Parikh NU, Woodruff TM, Jarvis JN, Lopez M, Hennon T, Cunningham P, Quigg RJ, Schwartz SA, Alexander JJ.

Immunology. 2015 Jun 8. doi: 10.1111/imm.12489. [Epub ahead of print]

PMID:
26059553
4.
5.

Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1 G93A mouse model of amyotrophic lateral sclerosis.

Lee JY, Lee JD, Phipps S, Noakes PG, Woodruff TM.

J Neuroinflammation. 2015 May 13;12:90. doi: 10.1186/s12974-015-0310-z.

6.

The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis following Spinal Cord Injury.

Brennan FH, Gordon R, Lao HW, Biggins PJ, Taylor SM, Franklin RJ, Woodruff TM, Ruitenberg MJ.

J Neurosci. 2015 Apr 22;35(16):6517-31. doi: 10.1523/JNEUROSCI.5218-14.2015.

PMID:
25904802
7.

Is the complement activation product C3a a proinflammatory molecule? Re-evaluating the evidence and the myth.

Coulthard LG, Woodruff TM.

J Immunol. 2015 Apr 15;194(8):3542-8. doi: 10.4049/jimmunol.1403068. Review.

PMID:
25848071
8.

The Role of C5a Receptor Signaling in Endotoxin-Induced Miscarriage and Preterm Birth.

Denny KJ, Coulthard LG, Mantovani S, Simmons D, Taylor SM, Woodruff TM.

Am J Reprod Immunol. 2015 Aug;74(2):148-55. doi: 10.1111/aji.12386. Epub 2015 Apr 6.

PMID:
25846074
9.

Properdin provides protection from Citrobacter rodentium-induced intestinal inflammation in a C5a/IL-6-dependent manner.

Jain U, Cao Q, Thomas NA, Woodruff TM, Schwaeble WJ, Stover CM, Stadnyk AW.

J Immunol. 2015 Apr 1;194(7):3414-21. doi: 10.4049/jimmunol.1401814. Epub 2015 Feb 27.

PMID:
25725105
10.

A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy models.

Benson MJ, Thomas NK, Talwar S, Hodson MP, Lynch JW, Woodruff TM, Borges K.

Neurobiol Dis. 2015 Apr;76:87-97. doi: 10.1016/j.nbd.2015.02.004. Epub 2015 Feb 11.

PMID:
25681535
11.

Derivation of ligands for the complement C3a receptor from the C-terminus of C5a.

Halai R, Bellows-Peterson ML, Branchett W, Smadbeck J, Kieslich CA, Croker DE, Cooper MA, Morikis D, Woodruff TM, Floudas CA, Monk PN.

Eur J Pharmacol. 2014 Dec 15;745:176-81. doi: 10.1016/j.ejphar.2014.10.041. Epub 2014 Oct 30.

12.

Elevation of the terminal complement activation products C5a and C5b-9 in ALS patient blood.

Mantovani S, Gordon R, Macmaw JK, Pfluger CM, Henderson RD, Noakes PG, McCombe PA, Woodruff TM.

J Neuroimmunol. 2014 Nov 15;276(1-2):213-8.

PMID:
25262158
13.

Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methods.

Khan N, Woodruff TM, Smith MT.

Pharmacol Biochem Behav. 2014 Nov;126:13-27. doi: 10.1016/j.pbb.2014.09.003. Epub 2014 Sep 16.

PMID:
25223977
14.

Insights into the mechanism of C5aR inhibition by PMX53 via implicit solvent molecular dynamics simulations and docking.

Tamamis P, Kieslich CA, Nikiforovich GV, Woodruff TM, Morikis D, Archontis G.

BMC Biophys. 2014 Aug 12;7:5. doi: 10.1186/2046-1682-7-5. eCollection 2014.

15.

Brief report: complement C5a promotes human embryonic stem cell pluripotency in the absence of FGF2.

Hawksworth OA, Coulthard LG, Taylor SM, Wolvetang EJ, Woodruff TM.

Stem Cells. 2014 Dec;32(12):3278-84. doi: 10.1002/stem.1801.

PMID:
25132103
16.

Placental lipases in pregnancies complicated by gestational diabetes mellitus (GDM).

Barrett HL, Kubala MH, Scholz Romero K, Denny KJ, Woodruff TM, McIntyre HD, Callaway LK, Nitert MD.

PLoS One. 2014 Aug 12;9(8):e104826. doi: 10.1371/journal.pone.0104826. eCollection 2014.

17.

Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injury.

De Hoog VC, Timmers L, Van Duijvenvoorde A, De Jager SC, Van Middelaar BJ, Smeets MB, Woodruff TM, Doevendans PA, Pasterkamp G, Hack CE, De Kleijn DP.

Cardiovasc Res. 2014 Sep 1;103(4):521-9. doi: 10.1093/cvr/cvu153. Epub 2014 Jun 15.

PMID:
24935433
18.

Flexible binding of PNP pincer ligands to monomeric iron complexes.

Fillman KL, Bielinski EA, Schmeier TJ, Nesvet JC, Woodruff TM, Pan CJ, Takase MK, Hazari N, Neidig ML.

Inorg Chem. 2014 Jun 16;53(12):6066-72. doi: 10.1021/ic5004275. Epub 2014 May 30.

PMID:
24878059
19.

'Unconventional' coordination chemistry by metal chelating fragments in a metalloprotein active site.

Martin DP, Blachly PG, Marts AR, Woodruff TM, de Oliveira CA, McCammon JA, Tierney DL, Cohen SM.

J Am Chem Soc. 2014 Apr 9;136(14):5400-6. doi: 10.1021/ja500616m. Epub 2014 Mar 27.

20.

Increased placental expression of fibroblast growth factor 21 in gestational diabetes mellitus.

Dekker Nitert M, Barrett HL, Kubala MH, Scholz Romero K, Denny KJ, Woodruff TM, McIntyre HD, Callaway LK.

J Clin Endocrinol Metab. 2014 Apr;99(4):E591-8. doi: 10.1210/jc.2013-2581. Epub 2014 Jan 16.

PMID:
24432989
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