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Items: 1 to 20 of 94

1.

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.

Arbore G, West EE, Spolski R, Robertson AA, Klos A, Rheinheimer C, Dutow P, Woodruff TM, Yu ZX, O'Neill LA, Coll RC, Sher A, Leonard WJ, Köhl J, Monk P, Cooper MA, Arno M, Afzali B, Lachmann HJ, Cope AP, Mayer-Barber KD, Kemper C.

Science. 2016 Jun 17;352(6292):aad1210. doi: 10.1126/science.aad1210.

PMID:
27313051
2.

Release of bioactive peptides from polyurethane films in vitro and in vivo: Effect of polymer composition.

Zhang J, Woodruff TM, Clark RJ, Martin DJ, Minchin RF.

Acta Biomater. 2016 May 28. pii: S1742-7061(16)30252-5. doi: 10.1016/j.actbio.2016.05.034. [Epub ahead of print]

PMID:
27245428
3.

C5a induces caspase dependent apoptosis in brain vascular endothelial cells in experimental lupus.

Mahajan SD, Tutino VM, Redae Y, Meng H, Siddiqui A, Woodruff TM, Jarvis JN, Hennon T, Schwartz S, Quigg RJ, Alexander JJ.

Immunology. 2016 May 23. doi: 10.1111/imm.12619. [Epub ahead of print]

PMID:
27213693
4.

Comparison of Measured to Predicted Estimations of Nonpoint Source Contaminants Using Conservation Practices in an Agriculturally-Dominated Watershed in Northeast Arkansas, USA.

Frasher SK, Woodruff TM, Bouldin JL.

Bull Environ Contam Toxicol. 2016 Jun;96(6):762-6. doi: 10.1007/s00128-016-1823-6. Epub 2016 May 19.

PMID:
27194420
5.

The Complement C3a Receptor Contributes to Melanoma Tumorigenesis by Inhibiting Neutrophil and CD4+ T Cell Responses.

Nabizadeh JA, Manthey HD, Steyn FJ, Chen W, Widiapradja A, Md Akhir FN, Boyle GM, Taylor SM, Woodruff TM, Rolfe BE.

J Immunol. 2016 Jun 1;196(11):4783-92. doi: 10.4049/jimmunol.1600210. Epub 2016 Apr 20.

PMID:
27183625
6.

The Complement System Component C5a Produces Thermal Hyperalgesia via Macrophage-to-Nociceptor Signaling That Requires NGF and TRPV1.

Shutov LP, Warwick CA, Shi X, Gnanasekaran A, Shepherd AJ, Mohapatra DP, Woodruff TM, Clark JD, Usachev YM.

J Neurosci. 2016 May 4;36(18):5055-70. doi: 10.1523/JNEUROSCI.3249-15.2016.

PMID:
27147658
7.

Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signalling.

Croker DE, Monk PN, Halai R, Kaeslin G, Schofield Z, Wu MC, Clark RJ, Blaskovich MA, Morikis D, Floudas CA, Cooper MA, Woodruff TM.

Immunol Cell Biol. 2016 May 17. doi: 10.1038/icb.2016.43. [Epub ahead of print]

PMID:
27108698
8.

Therapeutic targeting of complement to modify disease course and improve outcomes in neurological conditions.

Brennan FH, Lee JD, Ruitenberg MJ, Woodruff TM.

Semin Immunol. 2016 Apr 2. pii: S1044-5323(16)00022-1. doi: 10.1016/j.smim.2016.03.015. [Epub ahead of print] Review.

PMID:
27049459
9.

Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosis.

Gu H, Fisher AJ, Mickler EA, Duerson F 3rd, Cummings OW, Peters-Golden M, Twigg HL 3rd, Woodruff TM, Wilkes DS, Vittal R.

FASEB J. 2016 Jun;30(6):2336-50. doi: 10.1096/fj.201500044. Epub 2016 Mar 8.

PMID:
26956419
10.

Motor deficits associated with Huntington's disease occur in the absence of striatal degeneration in BACHD transgenic mice.

Mantovani S, Gordon R, Li R, Christie DC, Kumar V, Woodruff TM.

Hum Mol Genet. 2016 Feb 21. pii: ddw050. [Epub ahead of print]

PMID:
26908618
11.

Autoantibodies against homocysteinylated protein in a mouse model of folate deficiency-induced neural tube defects.

Denny KJ, Kelly CF, Kumar V, Witham KL, Cabrera RM, Finnell RH, Taylor SM, Jeanes A, Woodruff TM.

Birth Defects Res A Clin Mol Teratol. 2016 Mar;106(3):201-7. doi: 10.1002/bdra.23483. Epub 2016 Feb 22.

PMID:
26900104
12.

EPHA4-FC TREATMENT REDUCES ISCHEMIA/REPERFUSION-INDUCED INTESTINAL INJURY BY INHIBITING VASCULAR PERMEABILITY.

Woodruff TM, Wu MC, Morgan M, Bain NT, Jeanes A, Lipman J, Ting MJ, Boyd AW, Taylor SM, Coulthard MG.

Shock. 2016 Feb;45(2):184-91. doi: 10.1097/SHK.0000000000000494.

PMID:
26771935
13.

The Receptor for Advanced Glycation Endproducts Does Not Contribute to Pathology in a Mouse Mesenteric Ischemia/Reperfusion-Induced Injury Model.

Wu MC, Gilmour TD, Mantovani S, Woodruff TM.

Front Immunol. 2015 Dec 7;6:614. doi: 10.3389/fimmu.2015.00614. eCollection 2015.

14.

Co-ordinated expression of innate immune molecules during mouse neurulation.

Jeanes A, Coulthard LG, Mantovani S, Markham K, Woodruff TM.

Mol Immunol. 2015 Dec;68(2 Pt A):253-60. doi: 10.1016/j.molimm.2015.09.004. Epub 2015 Sep 14.

PMID:
26383831
15.

Placental lipase expression in pregnancies complicated by preeclampsia: a case-control study.

Barrett HL, Kubala MH, Scholz Romero K, Denny KJ, Woodruff TM, McIntyre HD, Callaway LK, Dekker Nitert M.

Reprod Biol Endocrinol. 2015 Sep 4;13:100. doi: 10.1186/s12958-015-0098-9.

16.

Altered expression of metabolic proteins and adipokines in patients with amyotrophic lateral sclerosis.

Ngo ST, Steyn FJ, Huang L, Mantovani S, Pfluger CM, Woodruff TM, O'Sullivan JD, Henderson RD, McCombe PA.

J Neurol Sci. 2015 Oct 15;357(1-2):22-7. doi: 10.1016/j.jns.2015.06.053. Epub 2015 Jul 6.

17.
18.

C5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosus.

Mahajan SD, Parikh NU, Woodruff TM, Jarvis JN, Lopez M, Hennon T, Cunningham P, Quigg RJ, Schwartz SA, Alexander JJ.

Immunology. 2015 Sep;146(1):130-43. doi: 10.1111/imm.12489. Epub 2015 Jul 15.

PMID:
26059553
19.
20.

Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1 G93A mouse model of amyotrophic lateral sclerosis.

Lee JY, Lee JD, Phipps S, Noakes PG, Woodruff TM.

J Neuroinflammation. 2015 May 13;12:90. doi: 10.1186/s12974-015-0310-z.

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