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Results: 1 to 20 of 21

1.

Admixture facilitates genetic adaptations to high altitude in Tibet.

Jeong C, Alkorta-Aranburu G, Basnyat B, Neupane M, Witonsky DB, Pritchard JK, Beall CM, Di Rienzo A.

Nat Commun. 2014;5:3281. doi: 10.1038/ncomms4281.

PMID:
24513612
[PubMed - in process]
2.

Genetic mapping with multiple levels of phenotypic information reveals determinants of lymphocyte glucocorticoid sensitivity.

Maranville JC, Baxter SS, Witonsky DB, Chase MA, Di Rienzo A.

Am J Hum Genet. 2013 Oct 3;93(4):735-43. doi: 10.1016/j.ajhg.2013.08.005. Epub 2013 Sep 19.

PMID:
24055111
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Genetic, functional and molecular features of glucocorticoid receptor binding.

Luca F, Maranville JC, Richards AL, Witonsky DB, Stephens M, Di Rienzo A.

PLoS One. 2013 Apr 30;8(4):e61654. doi: 10.1371/journal.pone.0061654. Print 2013.

PMID:
23637875
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The genetic architecture of adaptations to high altitude in Ethiopia.

Alkorta-Aranburu G, Beall CM, Witonsky DB, Gebremedhin A, Pritchard JK, Di Rienzo A.

PLoS Genet. 2012;8(12):e1003110. doi: 10.1371/journal.pgen.1003110. Epub 2012 Dec 6.

PMID:
23236293
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Reconstructing Native American population history.

Reich D, Patterson N, Campbell D, Tandon A, Mazieres S, Ray N, Parra MV, Rojas W, Duque C, Mesa N, García LF, Triana O, Blair S, Maestre A, Dib JC, Bravi CM, Bailliet G, Corach D, Hünemeier T, Bortolini MC, Salzano FM, Petzl-Erler ML, Acuña-Alonzo V, Aguilar-Salinas C, Canizales-Quinteros S, Tusié-Luna T, Riba L, Rodríguez-Cruz M, Lopez-Alarcón M, Coral-Vazquez R, Canto-Cetina T, Silva-Zolezzi I, Fernandez-Lopez JC, Contreras AV, Jimenez-Sanchez G, Gómez-Vázquez MJ, Molina J, Carracedo A, Salas A, Gallo C, Poletti G, Witonsky DB, Alkorta-Aranburu G, Sukernik RI, Osipova L, Fedorova SA, Vasquez R, Villena M, Moreau C, Barrantes R, Pauls D, Excoffier L, Bedoya G, Rothhammer F, Dugoujon JM, Larrouy G, Klitz W, Labuda D, Kidd J, Kidd K, Di Rienzo A, Freimer NB, Price AL, Ruiz-Linares A.

Nature. 2012 Aug 16;488(7411):370-4. doi: 10.1038/nature11258. Erratum in: Nature. 2012 Nov 8;491(7423):288.

PMID:
22801491
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellular response phenotypes.

Maranville JC, Luca F, Richards AL, Wen X, Witonsky DB, Baxter S, Stephens M, Di Rienzo A.

PLoS Genet. 2011 Jul;7(7):e1002162. doi: 10.1371/journal.pgen.1002162. Epub 2011 Jul 7.

PMID:
21750684
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A signature of balancing selection in the region upstream to the human UGT2B4 gene and implications for breast cancer risk.

Sun C, Huo D, Southard C, Nemesure B, Hennis A, Cristina Leske M, Wu SY, Witonsky DB, Olopade OI, Di Rienzo A.

Hum Genet. 2011 Dec;130(6):767-75. doi: 10.1007/s00439-011-1025-6. Epub 2011 Jun 10.

PMID:
21660508
[PubMed - indexed for MEDLINE]
8.

A reduced representation approach to population genetic analyses and applications to human evolution.

Luca F, Hudson RR, Witonsky DB, Di Rienzo A.

Genome Res. 2011 Jul;21(7):1087-98. doi: 10.1101/gr.119792.110. Epub 2011 May 31.

PMID:
21628451
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Adaptations to climate-mediated selective pressures in humans.

Hancock AM, Witonsky DB, Alkorta-Aranburu G, Beall CM, Gebremedhin A, Sukernik R, Utermann G, Pritchard JK, Coop G, Di Rienzo A.

PLoS Genet. 2011 Apr;7(4):e1001375. doi: 10.1371/journal.pgen.1001375. Epub 2011 Apr 21.

PMID:
21533023
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

SNP discovery, expression and cis-regulatory variation in the UGT2B genes.

Sun C, Southard C, Huo D, Hernandez RD, Witonsky DB, Olopade OI, Di Rienzo A.

Pharmacogenomics J. 2012 Aug;12(4):287-96. doi: 10.1038/tpj.2011.2. Epub 2011 Mar 1.

PMID:
21358749
[PubMed - indexed for MEDLINE]
11.

Natural selection and functional genetic variation in the p53 pathway.

Sucheston L, Witonsky DB, Hastings D, Yildiz O, Clark VJ, Di Rienzo A, Onel K.

Hum Mol Genet. 2011 Apr 15;20(8):1502-8. doi: 10.1093/hmg/ddr028. Epub 2011 Jan 25.

PMID:
21266458
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Allele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations.

Sun C, Southard C, Witonsky DB, Kittler R, Di Rienzo A.

PLoS Genet. 2010 Oct 28;6(10):e1001178. doi: 10.1371/journal.pgen.1001178.

PMID:
21060808
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Adaptations to new environments in humans: the role of subtle allele frequency shifts.

Hancock AM, Alkorta-Aranburu G, Witonsky DB, Di Rienzo A.

Philos Trans R Soc Lond B Biol Sci. 2010 Aug 27;365(1552):2459-68. doi: 10.1098/rstb.2010.0032.

PMID:
20643735
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Using environmental correlations to identify loci underlying local adaptation.

Coop G, Witonsky D, Di Rienzo A, Pritchard JK.

Genetics. 2010 Aug;185(4):1411-23. doi: 10.1534/genetics.110.114819. Epub 2010 Jun 1.

PMID:
20516501
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Colloquium paper: human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency.

Hancock AM, Witonsky DB, Ehler E, Alkorta-Aranburu G, Beall C, Gebremedhin A, Sukernik R, Utermann G, Pritchard J, Coop G, Di Rienzo A.

Proc Natl Acad Sci U S A. 2010 May 11;107 Suppl 2:8924-30. doi: 10.1073/pnas.0914625107. Epub 2010 May 5.

PMID:
20445095
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Allelic imbalance (AI) identifies novel tissue-specific cis-regulatory variation for human UGT2B15.

Sun C, Southard C, Witonsky DB, Olopade OI, Di Rienzo A.

Hum Mutat. 2010 Jan;31(1):99-107. doi: 10.1002/humu.21145.

PMID:
19847790
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Adaptive variation regulates the expression of the human SGK1 gene in response to stress.

Luca F, Kashyap S, Southard C, Zou M, Witonsky D, Di Rienzo A, Conzen SD.

PLoS Genet. 2009 May;5(5):e1000489. doi: 10.1371/journal.pgen.1000489. Epub 2009 May 22.

PMID:
19461886
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Adaptations to climate in candidate genes for common metabolic disorders.

Hancock AM, Witonsky DB, Gordon AS, Eshel G, Pritchard JK, Coop G, Di Rienzo A.

PLoS Genet. 2008 Feb;4(2):e32. doi: 10.1371/journal.pgen.0040032.

PMID:
18282109
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Prevalence of common disease-associated variants in Asian Indians.

Pemberton TJ, Mehta NU, Witonsky D, Di Rienzo A, Allayee H, Conti DV, Patel PI.

BMC Genet. 2008 Feb 4;9:13. doi: 10.1186/1471-2156-9-13.

PMID:
18248681
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Comparative genomics analysis of human sequence variation in the UGT1A gene cluster.

Maitland ML, Grimsley C, Kuttab-Boulos H, Witonsky D, Kasza KE, Yang L, Roe BA, Di Rienzo A.

Pharmacogenomics J. 2006 Jan-Feb;6(1):52-62.

PMID:
16314881
[PubMed - indexed for MEDLINE]

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