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Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.

Onengut-Gumuscu S, Chen WM, Burren O, Cooper NJ, Quinlan AR, Mychaleckyj JC, Farber E, Bonnie JK, Szpak M, Schofield E, Achuthan P, Guo H, Fortune MD, Stevens H, Walker NM, Ward LD, Kundaje A, Kellis M, Daly MJ, Barrett JC, Cooper JD, Deloukas P; Type 1 Diabetes Genetics Consortium, Todd JA, Wallace C, Concannon P, Rich SS.

Nat Genet. 2015 Apr;47(4):381-6. doi: 10.1038/ng.3245. Epub 2015 Mar 9.


Effect of long-term starvation on the survival, recovery, and carbon utilization profiles of a bovine Escherichia coli O157:H7 isolate from New Zealand.

Xavier RN, Morgan HW, McDonald IR, Withers H.

Appl Environ Microbiol. 2014 Jul;80(14):4383-90. doi: 10.1128/AEM.00045-14. Epub 2014 May 9.


Relationship between insulin-like growth factor I levels, early insulin treatment, and clinical outcomes of very low birth weight infants.

Beardsall K, Vanhaesebrouck S, Frystyk J, Ogilvy-Stuart AL, Vanhole C, van Weissenbruch M, Midgley P, Thio M, Cornette L, Gill B, Ossuetta I, Iglesias I, Theyskens C, de Jong M, Ahluwalia JS, de Zegher F, Dunger DB; NIRTURE Study Group.

J Pediatr. 2014 May;164(5):1038-1044.e1. doi: 10.1016/j.jpeds.2013.12.046. Epub 2014 Feb 8.


Use of the LQ model with large fraction sizes results in underestimation of isoeffect doses.

Sheu T, Molkentine J, Transtrum MK, Buchholz TA, Withers HR, Thames HD, Mason KA.

Radiother Oncol. 2013 Oct;109(1):21-5. doi: 10.1016/j.radonc.2013.08.027. Epub 2013 Sep 20.


We forget at our peril the lessons built into the α/β model.

Brenner DJ, Sachs RK, Peters LJ, Withers HR, Hall EJ.

Int J Radiat Oncol Biol Phys. 2012 Mar 15;82(4):1312-4. doi: 10.1016/j.ijrobp.2011.12.045. No abstract available.


Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry.

Hunt KA, Smyth DJ, Balschun T, Ban M, Mistry V, Ahmad T, Anand V, Barrett JC, Bhaw-Rosun L, Bockett NA, Brand OJ, Brouwer E, Concannon P, Cooper JD, Dias KR, van Diemen CC, Dubois PC, Edkins S, Fölster-Holst R, Fransen K, Glass DN, Heap GA, Hofmann S, Huizinga TW, Hunt S, Langford C, Lee J, Mansfield J, Marrosu MG, Mathew CG, Mein CA, Müller-Quernheim J, Nutland S, Onengut-Gumuscu S, Ouwehand W, Pearce K, Prescott NJ, Posthumus MD, Potter S, Rosati G, Sambrook J, Satsangi J, Schreiber S, Shtir C, Simmonds MJ, Sudman M, Thompson SD, Toes R, Trynka G, Vyse TJ, Walker NM, Weidinger S, Zhernakova A, Zoledziewska M; Type 1 Diabetes Genetics Consortium; UK Inflammatory Bowel Disease (IBD) Genetics Consortium; Wellcome Trust Case Control Consortium, Weersma RK, Gough SC, Sawcer S, Wijmenga C, Parkes M, Cucca F, Franke A, Deloukas P, Rich SS, Todd JA, van Heel DA.

Nat Genet. 2011 Dec 27;44(1):3-5. doi: 10.1038/ng.1037. No abstract available.


Designing and implementing sample and data collection for an international genetics study: the Type 1 Diabetes Genetics Consortium (T1DGC).

Hilner JE, Perdue LH, Sides EG, Pierce JJ, Wägner AM, Aldrich A, Loth A, Albret L, Wagenknecht LE, Nierras C, Akolkar B; T1DGC.

Clin Trials. 2010;7(1 Suppl):S5-S32. doi: 10.1177/1740774510373497. Epub 2010 Jul 5.


Uropathogenic Escherichia coli forms biofilm aggregates under iron restriction that disperse upon the supply of iron.

Rowe MC, Withers HL, Swift S.

FEMS Microbiol Lett. 2010 Jun;307(1):102-9. doi: 10.1111/j.1574-6968.2010.01968.x. Epub 2010 Mar 25.


Hypoxia and the metabolic phenotype of prostate cancer cells.

Higgins LH, Withers HG, Garbens A, Love HD, Magnoni L, Hayward SW, Moyes CD.

Biochim Biophys Acta. 2009 Dec;1787(12):1433-43. doi: 10.1016/j.bbabio.2009.06.003. Epub 2009 Jun 12.


Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.

Barrett JC, Clayton DG, Concannon P, Akolkar B, Cooper JD, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Plagnol V, Pociot F, Schuilenburg H, Smyth DJ, Stevens H, Todd JA, Walker NM, Rich SS; Type 1 Diabetes Genetics Consortium.

Nat Genet. 2009 Jun;41(6):703-7. doi: 10.1038/ng.381. Epub 2009 May 10.


Comment on editorial "Magical protons" by Dr. Michael Goitein (Int J Radiat Oncol Biol Phys 2008;70:654-656) and in reply to Dr. Fowler.

Withers HR, Peters LJ.

Int J Radiat Oncol Biol Phys. 2008 Nov 15;72(4):1271. doi: 10.1016/j.ijrobp.2008.07.013. No abstract available.


Stereotactic radiotherapy for stage I non-small-cell lung cancer--the triumph of technology over biology?

Ball D, Withers HR.

Nat Clin Pract Oncol. 2007 Nov;4(11):614-5. Epub 2007 Sep 11. No abstract available.


Quality of life after surgery, external beam irradiation, or brachytherapy for early-stage prostate cancer.

Litwin MS, Gore JL, Kwan L, Brandeis JM, Lee SP, Withers HR, Reiter RE.

Cancer. 2007 Jun 1;109(11):2239-47.


The biological effectiveness of antiproton irradiation.

Holzscheiter MH, Bassler N, Agazaryan N, Beyer G, Blackmore E, DeMarco JJ, Doser M, Durand RE, Hartley O, Iwamoto KS, Knudsen HV, Landua R, Maggiore C, McBride WH, Møller SP, Petersen J, Skarsgard LD, Smathers JB, Solberg TD, Uggerhøj UI, Vranjes S, Withers HR, Wong M, Wouters BG.

Radiother Oncol. 2006 Dec;81(3):233-42. Epub 2006 Oct 27.


Inhibition of cellular respiration by doxorubicin.

Tao Z, Withers HG, Penefsky HS, Goodisman J, Souid AK.

Chem Res Toxicol. 2006 Aug;19(8):1051-8.


Regulatory roles of spnT, a novel gene located within transposon TnTIR.

Wei JR, Soo PC, Horng YT, Hsieh SC, Tsai YH, Swift S, Withers H, Williams P, Lai HC.

Biochem Biophys Res Commun. 2006 Sep 29;348(3):1038-46. Epub 2006 Aug 1.


In regard to Ciernik et al.: Automated functional image-guided radiation treatment planning for rectal cancer (Int J Radiat Oncol Biol Phys 2005;62:893-900).

Roels S, Haustermans K, Grégoire V, Withers HR.

Int J Radiat Oncol Biol Phys. 2006 Apr 1;64(5):1611-2; author reply 1612-3. No abstract available.


Modeling growth kinetics and statistical distribution of oligometastases.

Withers HR, Lee SP.

Semin Radiat Oncol. 2006 Apr;16(2):111-9. Review.


HosA, a member of the SlyA family, regulates motility in enteropathogenic Escherichia coli.

Ferrándiz MJ, Bishop K, Williams P, Withers H.

Infect Immun. 2005 Mar;73(3):1684-94.

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