Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 297

1.

Ring-Strain-Enabled Reaction Discovery: New Heterocycles from Bicyclo[1.1.0]butanes.

Walczak MA, Krainz T, Wipf P.

Acc Chem Res. 2015 Apr 21;48(4):1149-58. doi: 10.1021/ar500437h. Epub 2015 Mar 16.

PMID:
25775119
2.

Heat shock protein defenses in the neocortex and allocortex of the telencephalon.

Posimo JM, Weilnau JN, Gleixner AM, Broeren MT, Weiland NL, Brodsky JL, Wipf P, Leak RK.

Neurobiol Aging. 2015 Feb 18. pii: S0197-4580(15)00111-6. doi: 10.1016/j.neurobiolaging.2015.02.011. [Epub ahead of print]

PMID:
25771395
3.

SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest.

Tandon M, Salamoun JM, Carder EJ, Farber E, Xu S, Deng F, Tang H, Wipf P, Wang QJ.

PLoS One. 2015 Mar 6;10(3):e0119346. doi: 10.1371/journal.pone.0119346. eCollection 2015.

4.

Synthesis and biological evaluation of 3-aminoisoquinolin-1(2H)-one based inhibitors of the dual-specificity phosphatase Cdc25B.

George Rosenker KM, Paquette WD, Johnston PA, Sharlow ER, Vogt A, Bakan A, Lazo JS, Wipf P.

Bioorg Med Chem. 2015 Jan 31. pii: S0968-0896(15)00067-X. doi: 10.1016/j.bmc.2015.01.043. [Epub ahead of print]

PMID:
25703307
5.

Heat shock protein responses to aging and proteotoxicity in the olfactory bulb.

Crum TS, Gleixner AM, Posimo JM, Mason DM, Broeren MT, Heinemann SD, Wipf P, Brodsky JL, Leak RK.

J Neurochem. 2015 Jan 29. doi: 10.1111/jnc.13041. [Epub ahead of print]

PMID:
25640060
6.

The combination of thioxodihydroquinazolinones and platinum drugs reverses platinum resistance in tumor cells by inducing mitochondrial apoptosis independent of Bax and Bak.

Qian W, Salamoun J, Wang J, Roginskaya V, Van Houten B, Wipf P.

Bioorg Med Chem Lett. 2015 Feb 15;25(4):856-63. doi: 10.1016/j.bmcl.2014.12.072. Epub 2014 Dec 30.

PMID:
25582599
7.
8.

Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats.

Escobales N, Nuñez RE, Jang S, Parodi-Rullan R, Ayala-Peña S, Sacher JR, Skoda EM, Wipf P, Frontera W, Javadov S.

J Mol Cell Cardiol. 2014 Dec;77:136-46. doi: 10.1016/j.yjmcc.2014.10.009. Epub 2014 Oct 23.

PMID:
25451170
9.

Synthesis and structure–activity relationships of small molecule inhibitors of the simian virus 40 T antigen oncoprotein, an anti-polyomaviral target.

Ireland AW, Gobillot TA, Gupta T, Seguin SP, Liang M, Resnick L, Goldberg MT, Manos-Turvey A, Pipas JM, Wipf P, Brodsky JL.

Bioorg Med Chem. 2014 Nov 15;22(22):6490-502.

PMID:
25440730
10.

Deciphering of mitochondrial cardiolipin oxidative signaling in cerebral ischemia-reperfusion.

Ji J, Baart S, Vikulina AS, Clark RS, Anthonymuthu TS, Tyurin VA, Du L, St Croix CM, Tyurina YY, Lewis J, Skoda EM, Kline AE, Kochanek PM, Wipf P, Kagan VE, Bayır H.

J Cereb Blood Flow Metab. 2015 Feb;35(2):319-28. doi: 10.1038/jcbfm.2014.204. Epub 2014 Nov 19.

PMID:
25407268
11.

2-Guanidinoquinazolines as new inhibitors of the STAT3 pathway.

LaPorte MG, da Paz Lima DJ, Zhang F, Sen M, Grandis JR, Camarco D, Hua Y, Johnston PA, Lazo JS, Resnick LO, Wipf P, Huryn DM.

Bioorg Med Chem Lett. 2014 Nov 1;24(21):5081-5. doi: 10.1016/j.bmcl.2014.09.001. Epub 2014 Sep 15.

PMID:
25288188
12.

Synthesis of phosphaguanidines by hydrophosphination of carbodiimides with phosphine boranes.

Busacca CA, Milligan JA, Rattanangkool E, Ramavarapu C, Chen A, Saha AK, Li Z, Lee H, Geib SJ, Wang G, Senanayake CH, Wipf P.

J Org Chem. 2014 Oct 17;79(20):9878-87. doi: 10.1021/jo501841s. Epub 2014 Oct 1.

PMID:
25271367
13.

Synaptic Pathophysiology and Treatment of Lambert-Eaton Myasthenic Syndrome.

Tarr TB, Wipf P, Meriney SD.

Mol Neurobiol. 2014 Sep 9. [Epub ahead of print]

PMID:
25195700
14.

Improved hematopoiesis in GS-nitroxide (JP4-039)-treated mouse long-term bone marrow cultures and radioresistance of derived bone marrow stromal cell lines.

Shinde A, Epperly MW, Cao S, Holt D, Goff J, Shields D, Franicola D, Wipf P, Wang H, Greenberger JS.

In Vivo. 2014 Sep-Oct;28(5):699-708.

PMID:
25189880
15.

An uncharged oxetanyl sulfoxide as a covalent modifier for improving aqueous solubility.

Skoda EM, Sacher JR, Kazancioglu MZ, Saha J, Wipf P.

ACS Med Chem Lett. 2014 Jun 27;5(8):900-4. doi: 10.1021/ml5001504. eCollection 2014 Aug 14.

PMID:
25147611
16.

Complete reversal of Lambert-Eaton myasthenic syndrome synaptic impairment by the combined use of a K+ channel blocker and a Ca2+ channel agonist.

Tarr TB, Lacomis D, Reddel SW, Liang M, Valdomir G, Frasso M, Wipf P, Meriney SD.

J Physiol. 2014 Aug 15;592(Pt 16):3687-96. doi: 10.1113/jphysiol.2014.276493. Epub 2014 Jul 11.

PMID:
25015919
17.

Effects of the bifunctional sulfoxide MMS350, a radiation mitigator, on hematopoiesis in long-term bone marrow cultures and on radioresistance of marrow stromal cell lines.

Shinde A, Epperly MW, Cao S, Franicola D, Shields D, Wang H, Wipf P, Sprachman MM, Greenberger JS.

In Vivo. 2014 Jul-Aug;28(4):457-65.

PMID:
24982210
18.

Esophageal radioprotection by swallowed JP4-039/F15 in thoracic-irradiated mice with transgenic lung tumors.

Epperly MW, Goff JP, Franicola D, Wang H, Wipf P, Li S, Greenberger JS.

In Vivo. 2014 Jul-Aug;28(4):435-40.

PMID:
24982207
19.

Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039.

Berhane H, Shinde A, Kalash R, Xu K, Epperly MW, Goff J, Franicola D, Zhang X, Dixon T, Shields D, Wang H, Wipf P, Li S, Gao X, Greenberger JS.

Radiat Res. 2014 Jul;182(1):35-49. doi: 10.1667/RR13633.1. Epub 2014 Jun 16.

PMID:
24932534
20.

The HSP70 modulator MAL3-101 inhibits Merkel cell carcinoma.

Adam C, Baeurle A, Brodsky JL, Wipf P, Schrama D, Becker JC, Houben R.

PLoS One. 2014 Apr 2;9(4):e92041. doi: 10.1371/journal.pone.0092041. eCollection 2014.

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk