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Results: 1 to 20 of 283

1.

An uncharged oxetanyl sulfoxide as a covalent modifier for improving aqueous solubility.

Skoda EM, Sacher JR, Kazancioglu MZ, Saha J, Wipf P.

ACS Med Chem Lett. 2014 Jun 27;5(8):900-4. doi: 10.1021/ml5001504. eCollection 2014 Aug 14.

PMID:
25147611
[PubMed]
2.

Complete reversal of Lambert-Eaton myasthenic syndrome synaptic impairment by the combined use of a K+ channel blocker and a Ca2+ channel agonist.

Tarr TB, Lacomis D, Reddel SW, Liang M, Valdomir G, Frasso M, Wipf P, Meriney SD.

J Physiol. 2014 Aug 15;592(Pt 16):3687-96. doi: 10.1113/jphysiol.2014.276493. Epub 2014 Jul 11.

PMID:
25015919
[PubMed - in process]
3.

Effects of the bifunctional sulfoxide MMS350, a radiation mitigator, on hematopoiesis in long-term bone marrow cultures and on radioresistance of marrow stromal cell lines.

Shinde A, Epperly MW, Cao S, Franicola D, Shields D, Wang H, Wipf P, Sprachman MM, Greenberger JS.

In Vivo. 2014 Jul-Aug;28(4):457-65.

PMID:
24982210
[PubMed - in process]
4.

Esophageal radioprotection by swallowed JP4-039/F15 in thoracic-irradiated mice with transgenic lung tumors.

Epperly MW, Goff JP, Franicola D, Wang H, Wipf P, Li S, Greenberger JS.

In Vivo. 2014 Jul-Aug;28(4):435-40.

PMID:
24982207
[PubMed - in process]
5.

Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039.

Berhane H, Shinde A, Kalash R, Xu K, Epperly MW, Goff J, Franicola D, Zhang X, Dixon T, Shields D, Wang H, Wipf P, Li S, Gao X, Greenberger JS.

Radiat Res. 2014 Jul;182(1):35-49. doi: 10.1667/RR13633.1. Epub 2014 Jun 16.

PMID:
24932534
[PubMed - in process]
6.

The HSP70 modulator MAL3-101 inhibits Merkel cell carcinoma.

Adam C, Baeurle A, Brodsky JL, Wipf P, Schrama D, Becker JC, Houben R.

PLoS One. 2014 Apr 2;9(4):e92041. doi: 10.1371/journal.pone.0092041. eCollection 2014.

PMID:
24694787
[PubMed - in process]
Free PMC Article
7.

Synthesis of heterocyclic triads by Pd-catalyzed cross-couplings and evaluation of their cell-specific toxicity profile.

Salamoun J, Anderson S, Burnett JC, Gussio R, Wipf P.

Org Lett. 2014 Apr 4;16(7):2034-7. doi: 10.1021/ol500620m. Epub 2014 Mar 18.

PMID:
24641272
[PubMed - indexed for MEDLINE]
8.

Protein kinase d as a potential chemotherapeutic target for colorectal cancer.

Wei N, Chu E, Wipf P, Schmitz JC.

Mol Cancer Ther. 2014 May;13(5):1130-41. doi: 10.1158/1535-7163.MCT-13-0880. Epub 2014 Mar 14.

PMID:
24634417
[PubMed - in process]
9.

Investigational inhibitors of PTP4A3 phosphatase as antineoplastic agents.

Sharlow ER, Wipf P, McQueeney KE, Bakan A, Lazo JS.

Expert Opin Investig Drugs. 2014 May;23(5):661-73. doi: 10.1517/13543784.2014.892579. Epub 2014 Mar 13.

PMID:
24625356
[PubMed - in process]
10.

Can Radiosensitivity Associated with Defects in DNA Repair be Overcome by Mitochondrial-Targeted Antioxidant Radioprotectors.

Greenberger JS, Berhane H, Shinde A, Rhieu BH, Bernard M, Wipf P, Skoda EM, Epperly MW.

Front Oncol. 2014 Feb 17;4:24. doi: 10.3389/fonc.2014.00024. eCollection 2014.

PMID:
24596683
[PubMed]
Free PMC Article
11.

Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitors.

Cifuentes-Pagano E, Saha J, Csányi G, Ghouleh IA, Sahoo S, Rodríguez A, Wipf P, Pagano PJ, Skoda EM.

Medchemcomm. 2013 Jul;4(7):1085-1092.

PMID:
24466406
[PubMed]
Free PMC Article
12.

The impact of ionizing radiation on placental trophoblasts.

Kanter DJ, O'Brien MB, Shi XH, Chu T, Mishima T, Beriwal S, Epperly MW, Wipf P, Greenberger JS, Sadovsky Y.

Placenta. 2014 Feb;35(2):85-91. doi: 10.1016/j.placenta.2013.12.011. Epub 2014 Jan 2.

PMID:
24418702
[PubMed - in process]
13.

Radiologic differences between bone marrow stromal and hematopoietic progenitor cell lines from Fanconi Anemia (Fancd2(-/-)) mice.

Berhane H, Epperly MW, Goff J, Kalash R, Cao S, Franicola D, Zhang X, Shields D, Houghton F, Wang H, Wipf P, Parmar K, Greenberger JS.

Radiat Res. 2014 Jan;181(1):76-89. doi: 10.1667/RR13405.1. Epub 2014 Jan 7.

PMID:
24397476
[PubMed - indexed for MEDLINE]
14.

Imidazolium compounds are active against all stages of Trypanosoma cruzi.

Faral-Tello P, Liang M, Mahler G, Wipf P, Robello C.

Int J Antimicrob Agents. 2014 Mar;43(3):262-8. doi: 10.1016/j.ijantimicag.2013.10.019. Epub 2013 Nov 20.

PMID:
24359836
[PubMed - in process]
15.

Growth arrest by the antitumor steroidal lactone withaferin A in human breast cancer cells is associated with down-regulation and covalent binding at cysteine 303 of β-tubulin.

Antony ML, Lee J, Hahm ER, Kim SH, Marcus AI, Kumari V, Ji X, Yang Z, Vowell CL, Wipf P, Uechi GT, Yates NA, Romero G, Sarkar SN, Singh SV.

J Biol Chem. 2014 Jan 17;289(3):1852-65. doi: 10.1074/jbc.M113.496844. Epub 2013 Dec 2.

PMID:
24297176
[PubMed - indexed for MEDLINE]
16.

Amelioration of radiation-induced pulmonary fibrosis by a water-soluble bifunctional sulfoxide radiation mitigator (MMS350).

Kalash R, Epperly MW, Goff J, Dixon T, Sprachman MM, Zhang X, Shields D, Cao S, Franicola D, Wipf P, Berhane H, Wang H, Au J, Greenberger JS.

Radiat Res. 2013 Nov;180(5):474-90. doi: 10.1667/RR3233.1. Epub 2013 Oct 14.

PMID:
24125487
[PubMed - indexed for MEDLINE]
17.

New pyrazolopyrimidine inhibitors of protein kinase d as potent anticancer agents for prostate cancer cells.

Tandon M, Johnson J, Li Z, Xu S, Wipf P, Wang QJ.

PLoS One. 2013 Sep 23;8(9):e75601. doi: 10.1371/journal.pone.0075601. eCollection 2013.

PMID:
24086585
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Pharmacologic profiling of phosphoinositide 3-kinase inhibitors as mitigators of ionizing radiation-induced cell death.

Lazo JS, Sharlow ER, Epperly MW, Lira A, Leimgruber S, Skoda EM, Wipf P, Greenberger JS.

J Pharmacol Exp Ther. 2013 Dec;347(3):669-80. doi: 10.1124/jpet.113.208421. Epub 2013 Sep 25.

PMID:
24068833
[PubMed - indexed for MEDLINE]
19.

Condensation reactions of guanidines with bis-electrophiles: Formation of highly nitrogenous heterocycles.

Arnold DM, Laporte MG, Anderson SM, Wipf P.

Tetrahedron. 2013 Sep 9;69(36):7719-7731.

PMID:
23976798
[PubMed]
20.

Evaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cells.

Goff JP, Shields DS, Wang H, Skoda EM, Sprachman MM, Wipf P, Garapati VK, Atkinson J, London B, Lazo JS, Kagan V, Epperly MW, Greenberger JS.

Exp Hematol. 2013 Nov;41(11):957-66. doi: 10.1016/j.exphem.2013.08.001. Epub 2013 Aug 7.

PMID:
23933481
[PubMed - indexed for MEDLINE]
Free PMC Article

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