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Items: 1 to 20 of 628


The Radical Chemistry and Cytotoxicity of Bioreductive 3-Substituted Quinoxaline di-N-Oxides.

Anderson RF, Yadav P, Shinde SS, Hong CR, Pullen SM, Reynisson J, Wilson WR, Hay MP.

Chem Res Toxicol. 2016 Jul 6. [Epub ahead of print]


Growth hormone receptor antagonism suppresses tumour regrowth after radiotherapy in an endometrial cancer xenograft model.

Evans A, Jamieson SM, Liu DX, Wilson WR, Perry JK.

Cancer Lett. 2016 Aug 28;379(1):117-23. doi: 10.1016/j.canlet.2016.05.031. Epub 2016 May 27.


Prosthetic pulmonary valve and pulmonary conduit endocarditis: clinical, microbiological and echocardiographic features in adults.

Miranda WR, Connolly HM, Bonnichsen CR, DeSimone DC, Dearani JA, Maleszewski JJ, Greason KL, Wilson WR, Baddour LM.

Eur Heart J Cardiovasc Imaging. 2016 Aug;17(8):936-43. doi: 10.1093/ehjci/jew086. Epub 2016 May 8.


Hypoxia-activated prodrugs: paths forward in the era of personalised medicine.

Hunter FW, Wouters BG, Wilson WR.

Br J Cancer. 2016 May 10;114(10):1071-7. doi: 10.1038/bjc.2016.79. Epub 2016 Apr 12.


Cardiovascular Implantable Electronic Device Infections due to Propionibacterium Species.

El Rafei A, Desimone DC, Sohail MR, Desimone CV, Steckelberg JM, Wilson WR, Baddour LM.

Pacing Clin Electrophysiol. 2016 Jun;39(6):522-30. doi: 10.1111/pace.12845. Epub 2016 Apr 22.


Beta-haemolytic streptococcal endocarditis: clinical presentation, management and outcomes.

El Rafei A, DeSimone DC, DeSimone CV, Lahr BD, Steckelberg JM, Sohail MR, Wilson WR, Baddour LM.

Infect Dis (Lond). 2016;48(5):373-8. doi: 10.3109/23744235.2015.1129672. Epub 2016 Jan 14.


Mechanisms and biomaterials in pH-responsive tumour targeted drug delivery: A review.

Kanamala M, Wilson WR, Yang M, Palmer BD, Wu Z.

Biomaterials. 2016 Apr;85:152-67. doi: 10.1016/j.biomaterials.2016.01.061. Epub 2016 Jan 29. Review.


Infective Endocarditis Involving the Pulmonary Valve.

Miranda WR, Connolly HM, DeSimone DC, Phillips SD, Wilson WR, Sohail MR, Steckelberg JM, Baddour LM.

Am J Cardiol. 2015 Dec 15;116(12):1928-31. doi: 10.1016/j.amjcard.2015.09.038. Epub 2015 Oct 9.


Clinical Presentation, Risk Factors, and Outcomes of Hematogenous Prosthetic Joint Infection in Patients with Staphylococcus aureus Bacteremia.

Tande AJ, Palraj BR, Osmon DR, Berbari EF, Baddour LM, Lohse CM, Steckelberg JM, Wilson WR, Sohail MR.

Am J Med. 2016 Feb;129(2):221.e11-20. doi: 10.1016/j.amjmed.2015.09.006. Epub 2015 Oct 8.


Temporal trends in infective endocarditis epidemiology from 2007 to 2013 in Olmsted County, MN.

DeSimone DC, Tleyjeh IM, Correa de Sa DD, Anavekar NS, Lahr BD, Sohail MR, Steckelberg JM, Wilson WR, Baddour LM.

Am Heart J. 2015 Oct;170(4):830-6. doi: 10.1016/j.ahj.2015.07.007. Epub 2015 Jul 17.


Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association.

Baddour LM, Wilson WR, Bayer AS, Fowler VG Jr, Tleyjeh IM, Rybak MJ, Barsic B, Lockhart PB, Gewitz MH, Levison ME, Bolger AF, Steckelberg JM, Baltimore RS, Fink AM, O'Gara P, Taubert KA; American Heart Association Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young, Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and Stroke Council.

Circulation. 2015 Oct 13;132(15):1435-86. doi: 10.1161/CIR.0000000000000296. Epub 2015 Sep 15. Review. Erratum in: Circulation. 2015 Oct 27;132(17):e215.


Trends in Infective Endocarditis Incidence, Microbiology, and Valve Replacement in the United States From 2000 to 2011: The Devil Is in the Details.

DeSimone DC, Wilson WR, Baddour LM.

J Am Coll Cardiol. 2015 Sep 8;66(10):1201-2. doi: 10.1016/j.jacc.2015.05.079. No abstract available.


Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs.

Hunter FW, Young RJ, Shalev Z, Vellanki RN, Wang J, Gu Y, Joshi N, Sreebhavan S, Weinreb I, Goldstein DP, Moffat J, Ketela T, Brown KR, Koritzinsky M, Solomon B, Rischin D, Wilson WR, Wouters BG.

Cancer Res. 2015 Oct 1;75(19):4211-23. doi: 10.1158/0008-5472.CAN-15-1107. Epub 2015 Aug 21.


Genitourinary Procedures as Risk Factors for Prosthetic Hip or Knee Infection: A Hospital-Based Prospective Case-Control Study.

Gupta A, Osmon DR, Hanssen AD, Lightner DJ, Wilson WR, Steckelberg JM, Baddour LM, Harmsen WS, Mandrekar JN, Berbari EF.

Open Forum Infect Dis. 2015 Jun 30;2(3):ofv097. doi: 10.1093/ofid/ofv097. eCollection 2015 Sep.


Incidence of Infective Endocarditis Due to Viridans Group Streptococci Before and After the 2007 American Heart Association's Prevention Guidelines: An Extended Evaluation of the Olmsted County, Minnesota, Population and Nationwide Inpatient Sample.

DeSimone DC, Tleyjeh IM, Correa de Sa DD, Anavekar NS, Lahr BD, Sohail MR, Steckelberg JM, Wilson WR, Baddour LM; Mayo Cardiovascular Infections Study Group.

Mayo Clin Proc. 2015 Jul;90(7):874-81. doi: 10.1016/j.mayocp.2015.04.019.


AKR1C3 is a biomarker of sensitivity to PR-104 in preclinical models of T-cell acute lymphoblastic leukemia.

Moradi Manesh D, El-Hoss J, Evans K, Richmond J, Toscan CE, Bracken LS, Hedrick A, Sutton R, Marshall GM, Wilson WR, Kurmasheva RT, Billups C, Houghton PJ, Smith MA, Carol H, Lock RB.

Blood. 2015 Sep 3;126(10):1193-202. doi: 10.1182/blood-2014-12-618900. Epub 2015 Jun 26.


Association of Mitral Valve Prolapse With Infective Endocarditis Due to Viridans Group Streptococci.

DeSimone DC, DeSimone CV, Tleyjeh IM, Correa de Sa DD, Anavekar NS, Lahr BD, Sohail MR, Steckelberg JM, Wilson WR, Baddour LM.

Clin Infect Dis. 2015 Aug 15;61(4):623-5. doi: 10.1093/cid/civ375. Epub 2015 May 11.


Pre-clinical activity of PR-104 as monotherapy and in combination with sorafenib in hepatocellular carcinoma.

Abbattista MR, Jamieson SM, Gu Y, Nickel JE, Pullen SM, Patterson AV, Wilson WR, Guise CP.

Cancer Biol Ther. 2015;16(4):610-22. doi: 10.1080/15384047.2015.1017171. Epub 2015 Apr 14.


Predicting Risk of Endocarditis Using a Clinical Tool (PREDICT): Scoring System to Guide Use of Echocardiography in the Management of Staphylococcus aureus Bacteremia.

Palraj BR, Baddour LM, Hess EP, Steckelberg JM, Wilson WR, Lahr BD, Sohail MR.

Clin Infect Dis. 2015 Jul 1;61(1):18-28. doi: 10.1093/cid/civ235. Epub 2015 Mar 25.


Phase I/II study of the hypoxia-activated prodrug PR104 in refractory/relapsed acute myeloid leukemia and acute lymphoblastic leukemia.

Konopleva M, Thall PF, Yi CA, Borthakur G, Coveler A, Bueso-Ramos C, Benito J, Konoplev S, Gu Y, Ravandi F, Jabbour E, Faderl S, Thomas D, Cortes J, Kadia T, Kornblau S, Daver N, Pemmaraju N, Nguyen HQ, Feliu J, Lu H, Wei C, Wilson WR, Melink TJ, Gutheil JC, Andreeff M, Estey EH, Kantarjian H.

Haematologica. 2015 Jul;100(7):927-34. doi: 10.3324/haematol.2014.118455. Epub 2015 Feb 14.

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