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High frequency of antidrug antibodies and association of random drug levels with efficacy in certolizumab pegol-treated patients with rheumatoid arthritis: results from the BRAGGSS cohort.

Jani M, Isaacs JD, Morgan AW, Wilson AG, Plant D, Hyrich KL, Chinoy H, Barton A; BRAGGSS.

Ann Rheum Dis. 2016 May 31. pii: annrheumdis-2015-208849. doi: 10.1136/annrheumdis-2015-208849. [Epub ahead of print]


Previously reported PDE3A-SLCO1C1 genetic variant does not correlate with anti-TNF response in a large UK rheumatoid arthritis cohort.

Smith SL, Plant D, Lee XH, Massey J, Hyrich K, Morgan AW, Wilson AG, Isaacs J, Barton A.

Pharmacogenomics. 2016 May;17(7):715-20. doi: 10.2217/pgs.16.16. Epub 2016 May 16.


Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase.

Tarver JE Jr, Pabba PK, Barbosa J, Han Q, Gardyan MW, Brommage R, Thompson AY, Schmidt JM, Wilson AG, He W, Lombardo VK, Carson KG.

Bioorg Med Chem Lett. 2016 Mar 15;26(6):1525-8. doi: 10.1016/j.bmcl.2016.02.021. Epub 2016 Feb 10.


4H-Thieno[3,2-c]chromene based inhibitors of Notum Pectinacetylesterase.

Han Q, Pabba PK, Barbosa J, Mabon R, Healy JP, Gardyan MW, Terranova KM, Brommage R, Thompson AY, Schmidt JM, Wilson AG, Xu X, Tarver JE Jr, Carson KG.

Bioorg Med Chem Lett. 2016 Feb 15;26(4):1184-7. doi: 10.1016/j.bmcl.2016.01.038. Epub 2016 Jan 18.


Differential Methylation as a Biomarker of Response to Etanercept in Patients With Rheumatoid Arthritis.

Plant D, Webster A, Nair N, Oliver J, Smith SL, Eyre S, Hyrich KL, Wilson AG, Morgan AW, Isaacs JD, Worthington J, Barton A.

Arthritis Rheumatol. 2016 Jun;68(6):1353-60. doi: 10.1002/art.39590. Epub 2016 Apr 21.


The relative value of two options for pigeons depends on their context.

Pinto C, Fortes I, Wilson AG, Zentall TR.

J Exp Anal Behav. 2016 Jan;105(1):176-83. doi: 10.1002/jeab.187.


Investigating CD11c expression as a potential genomic biomarker of response to TNF inhibitor biologics in whole blood rheumatoid arthritis samples.

Smith SL, Eyre S, Yarwood A, Hyrich K, Morgan AW, Wilson AG, Isaacs J; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate 6, Plant D, Barton A.

Arthritis Res Ther. 2015 Dec 14;17:359. doi: 10.1186/s13075-015-0868-y.


Genome-wide association meta-analyses to identify common genetic variants associated with hallux valgus in Caucasian and African Americans.

Hsu YH, Liu Y, Hannan MT, Maixner W, Smith SB, Diatchenko L, Golightly YM, Menz HB, Kraus VB, Doherty M, Wilson AG, Jordan JM.

J Med Genet. 2015 Nov;52(11):762-9. doi: 10.1136/jmedgenet-2015-103142. Epub 2015 Sep 2.


C5orf30 is a negative regulator of tissue damage in rheumatoid arthritis.

Muthana M, Hawtree S, Wilshaw A, Linehan E, Roberts H, Khetan S, Adeleke G, Wright F, Akil M, Fearon U, Veale D, Ciani B, Wilson AG.

Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11618-23. doi: 10.1073/pnas.1501947112. Epub 2015 Aug 27.


Clinical utility of random anti-tumour necrosis factor drug testing and measurement of anti-drug antibodies on long-term treatment response in rheumatoid arthritis.

Jani M, Chinoy H, Warren RB, Griffiths CE, Plant D, Morgan AW, Wilson AG, Hyrich KL, Isaacs J, Barton A.

Lancet. 2015 Feb 26;385 Suppl 1:S48. doi: 10.1016/S0140-6736(15)60363-4.


Genetic Divergence of an Avian Endemic on the Californian Channel Islands.

Wilson AG, Chan Y, Taylor SS, Arcese P.

PLoS One. 2015 Aug 26;10(8):e0134471. doi: 10.1371/journal.pone.0134471. eCollection 2015.


Behavioral Economics of Cigarette Purchase Tasks: Within-Subject Comparison of Real, Potentially Real, and Hypothetical Cigarettes.

Wilson AG, Franck CT, Koffarnus MN, Bickel WK.

Nicotine Tob Res. 2016 May;18(5):524-30. doi: 10.1093/ntr/ntv154. Epub 2015 Jul 17.


Histone deacetylase 1 regulates tissue destruction in rheumatoid arthritis.

Hawtree S, Muthana M, Wilkinson JM, Akil M, Wilson AG.

Hum Mol Genet. 2015 Oct 1;24(19):5367-77. doi: 10.1093/hmg/ddv258. Epub 2015 Jul 7.


Clinical utility of random anti-tumor necrosis factor drug-level testing and measurement of antidrug antibodies on the long-term treatment response in rheumatoid arthritis.

Jani M, Chinoy H, Warren RB, Griffiths CE, Plant D, Fu B, Morgan AW, Wilson AG, Isaacs JD, Hyrich K, Barton A; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate Collaborators.

Arthritis Rheumatol. 2015 May;67(8):2011-9. doi: 10.1002/art.39169. Erratum in: Arthritis Rheumatol. 2015 Nov;67(11):3096.


Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response.

Viatte S, Plant D, Han B, Fu B, Yarwood A, Thomson W, Symmons DP, Worthington J, Young A, Hyrich KL, Morgan AW, Wilson AG, Isaacs JD, Raychaudhuri S, Barton A.

JAMA. 2015 Apr 28;313(16):1645-56. doi: 10.1001/jama.2015.3435.


Rheumatoid arthritis response to treatment across IgG1 allotype - anti-TNF incompatibility: a case-only study.

Montes A, Perez-Pampin E, Navarro-Sarabia F, Moreira V, de la Serna AR, Magallares B, Vasilopoulos Y, Sarafidou T, Fernández-Nebro A, Ordóñez Mdel C, Narváez J, Cañete JD, Marquez A, Pascual-Salcedo D, Joven B, Carreira P, Moreno-Ramos MJ, Caliz R, Ferrer MA, Garcia-Portales R, Blanco FJ, Magro C, Raya E, Valor L, Alegre-Sancho JJ, Balsa A, Martin J, Plant D, Isaacs J, Morgan AW, Barton A, Wilson AG; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS), Gómez-Reino JJ, Gonzalez A.

Arthritis Res Ther. 2015 Mar 18;17:63. doi: 10.1186/s13075-015-0571-z.


The influence of multiple temporal memories in the peak-interval procedure.

Wilson AG, Matell MS, Crystal JD.

Learn Behav. 2015 Jun;43(2):153-62. doi: 10.3758/s13420-015-0169-y.


Discovery and Development of LX7101, a Dual LIM-Kinase and ROCK Inhibitor for the Treatment of Glaucoma.

Harrison BA, Almstead ZY, Burgoon H, Gardyan M, Goodwin NC, Healy J, Liu Y, Mabon R, Marinelli B, Samala L, Zhang Y, Stouch TR, Whitlock NA, Gopinathan S, McKnight B, Wang S, Patel N, Wilson AG, Hamman BD, Rice DS, Rawlins DB.

ACS Med Chem Lett. 2014 Nov 24;6(1):84-8. doi: 10.1021/ml500367g. eCollection 2015 Jan 8.

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