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Items: 1 to 20 of 124

1.

LRP2, an auxiliary receptor that controls sonic hedgehog signaling in development and disease.

Christ A, Herzog K, Willnow TE.

Dev Dyn. 2016 May;245(5):569-79. doi: 10.1002/dvdy.24394. Epub 2016 Mar 4. Review.

PMID:
26872844
2.

Protein sorting gone wrong - VPS10P domain receptors in cardiovascular and metabolic diseases.

Schmidt V, Willnow TE.

Atherosclerosis. 2016 Feb;245:194-9. doi: 10.1016/j.atherosclerosis.2015.11.027. Epub 2015 Dec 8. Review.

PMID:
26724530
3.

Role of Sortilin in Models of Autoimmune Neuroinflammation.

Reuter E, Weber J, Paterka M, Ploen R, Breiderhoff T, van Horssen J, Willnow TE, Siffrin V, Zipp F.

J Immunol. 2015 Dec 15;195(12):5762-9. doi: 10.4049/jimmunol.1403156. Epub 2015 Nov 13.

PMID:
26566674
4.

LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli.

Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE.

Dev Cell. 2015 Oct 12;35(1):36-48. doi: 10.1016/j.devcel.2015.09.001. Epub 2015 Oct 1.

PMID:
26439398
5.

Distinct Functions for Anterograde and Retrograde Sorting of SORLA in Amyloidogenic Processes in the Brain.

Dumanis SB, Burgert T, Caglayan S, Füchtbauer A, Füchtbauer EM, Schmidt V, Willnow TE.

J Neurosci. 2015 Sep 16;35(37):12703-13. doi: 10.1523/JNEUROSCI.0427-15.2015.

6.

Calcineurin and Sorting-Related Receptor with A-Type Repeats Interact to Regulate the Renal Na⁺-K⁺-2Cl⁻ Cotransporter.

Borschewski A, Himmerkus N, Boldt C, Blankenstein KI, McCormick JA, Lazelle R, Willnow TE, Jankowski V, Plain A, Bleich M, Ellison DH, Bachmann S, Mutig K.

J Am Soc Nephrol. 2016 Jan;27(1):107-19. doi: 10.1681/ASN.2014070728. Epub 2015 May 12.

PMID:
25967121
7.

SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia.

Glerup S, Olsen D, Vaegter CB, Gustafsen C, Sjoegaard SS, Hermey G, Kjolby M, Molgaard S, Ulrichsen M, Boggild S, Skeldal S, Fjorback AN, Nyengaard JR, Jacobsen J, Bender D, Bjarkam CR, Sørensen ES, Füchtbauer EM, Eichele G, Madsen P, Willnow TE, Petersen CM, Nykjaer A.

Neuron. 2014 Jun 4;82(5):1074-87. doi: 10.1016/j.neuron.2014.04.022.

8.

Sorting receptor sortilin-a culprit in cardiovascular and neurological diseases.

Carlo AS, Nykjaer A, Willnow TE.

J Mol Med (Berl). 2014 Sep;92(9):905-11. doi: 10.1007/s00109-014-1152-3. Epub 2014 May 18. Review.

PMID:
24838608
9.

LRP2 mediates folate uptake in the developing neural tube.

Kur E, Mecklenburg N, Cabrera RM, Willnow TE, Hammes A.

J Cell Sci. 2014 May 15;127(Pt 10):2261-8. doi: 10.1242/jcs.140145. Epub 2014 Mar 17.

10.

Apolipoprotein E receptor pathways in Alzheimer disease.

Schmidt V, Carlo AS, Willnow TE.

Wiley Interdiscip Rev Syst Biol Med. 2014 May-Jun;6(3):255-70. doi: 10.1002/wsbm.1262. Epub 2014 Mar 6. Review.

PMID:
24604742
11.

Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation.

Caglayan S, Takagi-Niidome S, Liao F, Carlo AS, Schmidt V, Burgert T, Kitago Y, Füchtbauer EM, Füchtbauer A, Holtzman DM, Takagi J, Willnow TE.

Sci Transl Med. 2014 Feb 12;6(223):223ra20. doi: 10.1126/scitranslmed.3007747.

12.

Disturbed function of the blood-cerebrospinal fluid barrier aggravates neuro-inflammation.

Kooij G, Kopplin K, Blasig R, Stuiver M, Koning N, Goverse G, van der Pol SM, van Het Hof B, Gollasch M, Drexhage JA, Reijerkerk A, Meij IC, Mebius R, Willnow TE, Müller D, Blasig IE, de Vries HE.

Acta Neuropathol. 2014 Aug;128(2):267-77. doi: 10.1007/s00401-013-1227-1. Epub 2013 Dec 20.

PMID:
24356983
13.

Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction.

Breiderhoff T, Christiansen GB, Pallesen LT, Vaegter C, Nykjaer A, Holm MM, Glerup S, Willnow TE.

PLoS One. 2013 Sep 19;8(9):e75006. doi: 10.1371/journal.pone.0075006. eCollection 2013.

14.

SORLA-dependent and -independent functions for PACS1 in control of amyloidogenic processes.

Burgert T, Schmidt V, Caglayan S, Lin F, Füchtbauer A, Füchtbauer EM, Nykjaer A, Carlo AS, Willnow TE.

Mol Cell Biol. 2013 Nov;33(21):4308-20. doi: 10.1128/MCB.00628-13. Epub 2013 Sep 3.

15.

SORLA-mediated trafficking of TrkB enhances the response of neurons to BDNF.

Rohe M, Hartl D, Fjorback AN, Klose J, Willnow TE.

PLoS One. 2013 Aug 19;8(8):e72164. doi: 10.1371/journal.pone.0072164. eCollection 2013.

16.

Sorting receptor SORLA--a trafficking path to avoid Alzheimer disease.

Willnow TE, Andersen OM.

J Cell Sci. 2013 Jul 1;126(Pt 13):2751-60. doi: 10.1242/jcs.125393. Epub 2013 Jun 26. Review.

17.

Soluble alpha-APP (sAPPalpha) regulates CDK5 expression and activity in neurons.

Hartl D, Klatt S, Roch M, Konthur Z, Klose J, Willnow TE, Rohe M.

PLoS One. 2013 Jun 11;8(6):e65920. doi: 10.1371/journal.pone.0065920. Print 2013.

18.

The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain.

Carlo AS, Gustafsen C, Mastrobuoni G, Nielsen MS, Burgert T, Hartl D, Rohe M, Nykjaer A, Herz J, Heeren J, Kempa S, Petersen CM, Willnow TE.

J Neurosci. 2013 Jan 2;33(1):358-70. doi: 10.1523/JNEUROSCI.2425-12.2013.

19.

Endocytic receptor-mediated control of morphogen signaling.

Willnow TE, Christ A, Hammes A.

Development. 2012 Dec 1;139(23):4311-9. doi: 10.1242/dev.084467. Review.

20.

The sorting receptor Sortilin exhibits a dual function in exocytic trafficking of interferon-γ and granzyme A in T cells.

Herda S, Raczkowski F, Mittrücker HW, Willimsky G, Gerlach K, Kühl AA, Breiderhoff T, Willnow TE, Dörken B, Höpken UE, Rehm A.

Immunity. 2012 Nov 16;37(5):854-66. doi: 10.1016/j.immuni.2012.07.012. Epub 2012 Oct 16.

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