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Results: 1 to 20 of 257

1.

Films loaded with insulin-coated nanoparticles (ICNP) as potential platforms for peptide buccal delivery.

Morales JO, Huang S, Williams RO 3rd, McConville JT.

Colloids Surf B Biointerfaces. 2014 Jun 23;122C:38-45. doi: 10.1016/j.colsurfb.2014.05.025. [Epub ahead of print]

PMID:
25016543
[PubMed - as supplied by publisher]
2.

Selective TNFR1 blockade is anti-inflammatory and reveals an immunoregulatory role for TNFR2.

McCann FE, Perocheau DP, Ruspi G, Blazek K, Davies ML, Feldmann M, Dean JL, Stoop AA, Williams RO.

Arthritis Rheumatol. 2014 Jun 25. doi: 10.1002/art.38755. [Epub ahead of print]

PMID:
24965881
[PubMed - as supplied by publisher]
3.

Regulatory T cell function in rheumatoid arthritis is compromised by CTLA-4 promoter methylation resulting in a failure to activate the IDO pathway.

Cribbs AP, Kennedy A, Penn H, Read JE, Amjadi P, Green P, Syed K, Manka SW, Brennan FM, Gregory B, Williams RO.

Arthritis Rheumatol. 2014 May 28. doi: 10.1002/art.38715. [Epub ahead of print]

PMID:
24891289
[PubMed - as supplied by publisher]
4.

In vitro and in vivo performance of dry powder inhalation formulations: comparison of particles prepared by thin film freezing and micronization.

Wang YB, Watts AB, Peters JI, Liu S, Batra A, Williams RO 3rd.

AAPS PharmSciTech. 2014 Aug;15(4):981-93. doi: 10.1208/s12249-014-0126-7. Epub 2014 May 14.

PMID:
24824172
[PubMed - in process]
5.

Solid lipid nanoparticle formulations of docetaxel prepared with high melting point triglycerides: in vitro and in vivo evaluation.

Naguib YW, Rodriguez BL, Li X, Hursting SD, Williams RO 3rd, Cui Z.

Mol Pharm. 2014 Apr 7;11(4):1239-49. doi: 10.1021/mp4006968. Epub 2014 Mar 12.

PMID:
24621456
[PubMed - in process]
6.

Hot-melt extrusion - basic principles and pharmaceutical applications.

Lang B, McGinity JW, Williams RO 3rd.

Drug Dev Ind Pharm. 2014 Sep;40(9):1133-55. doi: 10.3109/03639045.2013.838577. Epub 2014 Feb 13.

PMID:
24520867
[PubMed - in process]
7.

TNFR2 increases the sensitivity of ligand-induced activation of the p38 MAPK and NF-κB pathways and signals TRAF2 protein degradation in macrophages.

Ruspi G, Schmidt EM, McCann F, Feldmann M, Williams RO, Stoop AA, Dean JL.

Cell Signal. 2014 Apr;26(4):683-90. doi: 10.1016/j.cellsig.2013.12.009. Epub 2013 Dec 27.

PMID:
24378531
[PubMed - in process]
8.

Preparation of amorphous solid dispersions by rotary evaporation and KinetiSol Dispersing: approaches to enhance solubility of a poorly water-soluble gum extract.

Bennett RC, Brough C, Miller DA, O'Donnell KP, Keen JM, Hughey JR, Williams RO 3rd, McGinity JW.

Drug Dev Ind Pharm. 2013 Dec 16. [Epub ahead of print]

PMID:
24329130
[PubMed - as supplied by publisher]
9.

The impact of pulmonary diseases on the fate of inhaled medicines--a review.

Wang YB, Watts AB, Peters JI, Williams RO 3rd.

Int J Pharm. 2014 Jan 30;461(1-2):112-28. doi: 10.1016/j.ijpharm.2013.11.042. Epub 2013 Nov 27.

PMID:
24291124
[PubMed - in process]
10.

Dissolution enhancement of itraconazole by hot-melt extrusion alone and the combination of hot-melt extrusion and rapid freezing--effect of formulation and processing variables.

Lang B, McGinity JW, Williams RO 3rd.

Mol Pharm. 2014 Jan 6;11(1):186-96. doi: 10.1021/mp4003706. Epub 2013 Dec 11.

PMID:
24283890
[PubMed - in process]
11.

Heat shock protein B1-deficient mice display impaired wound healing.

Crowe J, Aubareda A, McNamee K, Przybycien PM, Lu X, Williams RO, Bou-Gharios G, Saklatvala J, Dean JL.

PLoS One. 2013 Oct 15;8(10):e77383. doi: 10.1371/journal.pone.0077383. eCollection 2013.

PMID:
24143227
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Blockade of tumour necrosis factor-α in experimental autoimmune encephalomyelitis reveals differential effects on the antigen-specific immune response and central nervous system histopathology.

Batoulis H, Recks MS, Holland FO, Thomalla F, Williams RO, Kuerten S.

Clin Exp Immunol. 2014 Jan;175(1):41-8. doi: 10.1111/cei.12209.

PMID:
24111507
[PubMed - indexed for MEDLINE]
13.

Recent advancements in mechanical reduction methods: particulate systems.

Leleux J, Williams RO 3rd.

Drug Dev Ind Pharm. 2014 Mar;40(3):289-300. doi: 10.3109/03639045.2013.828217. Epub 2013 Aug 30.

PMID:
23988193
[PubMed - in process]
14.

Exploitation of the IDO Pathway in the Therapy of Rheumatoid Arthritis.

Williams RO.

Int J Tryptophan Res. 2013 Jul 21;6(Suppl 1):67-73. doi: 10.4137/IJTR.S11737. Print 2013.

PMID:
23922504
[PubMed]
Free PMC Article
15.

Amorphous solid dispersions and nano-crystal technologies for poorly water-soluble drug delivery.

Brough C, Williams RO 3rd.

Int J Pharm. 2013 Aug 30;453(1):157-66. doi: 10.1016/j.ijpharm.2013.05.061. Epub 2013 Jun 7. Review.

PMID:
23751341
[PubMed - indexed for MEDLINE]
16.

Enhancing bioavailability through thermal processing.

Keen JM, McGinity JW, Williams RO 3rd.

Int J Pharm. 2013 Jun 25;450(1-2):185-96. doi: 10.1016/j.ijpharm.2013.04.042. Epub 2013 Apr 22. Review.

PMID:
23618970
[PubMed - indexed for MEDLINE]
17.

Nebulization of mycophenolate mofetil inhalation suspension in rats: comparison with oral and pulmonary administration of Cellcept®.

Dugas HL, Peters JI, Williams RO 3rd.

Int J Pharm. 2013 Jan 30;441(1-2):19-29. doi: 10.1016/j.ijpharm.2012.12.016. Epub 2012 Dec 20.

PMID:
23262419
[PubMed - indexed for MEDLINE]
18.

Respirable low-density microparticles formed in situ from aerosolized brittle matrices.

Watts AB, Wang YB, Johnston KP, Williams RO 3rd.

Pharm Res. 2013 Mar;30(3):813-25. doi: 10.1007/s11095-012-0922-2. Epub 2012 Nov 15.

PMID:
23229856
[PubMed - indexed for MEDLINE]
19.

Pulmonary dispersion formulations: the impact of dispersed powder properties on pressurized metered dose inhaler stability.

O'Donnell KP, Williams RO 3rd.

Drug Dev Ind Pharm. 2013 Mar;39(3):413-24. doi: 10.3109/03639045.2012.664145. Epub 2012 Dec 10. Review.

PMID:
23216244
[PubMed - indexed for MEDLINE]
20.

Formulation and delivery of improved amorphous fenofibrate solid dispersions prepared by thin film freezing.

Zhang M, Li H, Lang B, O'Donnell K, Zhang H, Wang Z, Dong Y, Wu C, Williams RO 3rd.

Eur J Pharm Biopharm. 2012 Nov;82(3):534-44. doi: 10.1016/j.ejpb.2012.06.016. Epub 2012 Sep 5.

PMID:
22974985
[PubMed - indexed for MEDLINE]

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