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Results: 1 to 20 of 264

1.

Anti-TNF treatment increases circulating Th17 cells similarly in different types of inflammatory arthritis.

Hull DN, Williams RO, Pathan E, Abraham S, Taylor PC.

Clin Exp Immunol. 2015 Mar 11. doi: 10.1111/cei.12626. [Epub ahead of print]

PMID:
25766640
2.

A method of lyophilizing vaccines containing aluminum salts into a dry powder without causing particle aggregation or decreasing the immunogenicity following reconstitution.

Li X, Thakkar SG, Ruwona TB, Williams RO 3rd, Cui Z.

J Control Release. 2015 Apr 28;204:38-50. doi: 10.1016/j.jconrel.2015.02.035. Epub 2015 Feb 28.

PMID:
25735896
3.

Reply to letter to the Editor.

Cribbs AP, Williams RO.

Arthritis Rheumatol. 2015 Jan 26. doi: 10.1002/art.39042. [Epub ahead of print] No abstract available.

PMID:
25622567
4.

Methotrexate restores regulatory T cell function through demethylation of the foxp3 upstream enhancer in patients with rheumatoid arthritis.

Cribbs AP, Kennedy A, Penn H, Amjadi P, Green P, Read JE, Brennan F, Gregory B, Williams RO.

Arthritis Rheumatol. 2015 Jan 20. doi: 10.1002/art.39031. [Epub ahead of print]

PMID:
25604080
5.

How do you use AAPS PharmSciTech?

Williams RO 3rd.

AAPS PharmSciTech. 2015 Feb;16(1):1-2. doi: 10.1208/s12249-014-0261-1. Epub 2015 Jan 6. No abstract available.

PMID:
25559372
6.

Nimesulide improves the symptomatic and disease modifying effects of leflunomide in collagen induced arthritis.

Al-Abd AM, Al-Abbasi FA, Nofal SM, Khalifa AE, Williams RO, El-Eraky WI, Nagy AA, Abdel-Naim AB.

PLoS One. 2014 Nov 6;9(11):e111843. doi: 10.1371/journal.pone.0111843. eCollection 2014.

7.

Combination cytokine blockade: the way forward in therapy for rheumatoid arthritis?

Taylor PC, Williams RO.

Arthritis Rheumatol. 2015 Jan;67(1):14-6. doi: 10.1002/art.38893. No abstract available.

PMID:
25302944
8.

Films loaded with insulin-coated nanoparticles (ICNP) as potential platforms for peptide buccal delivery.

Morales JO, Huang S, Williams RO 3rd, McConville JT.

Colloids Surf B Biointerfaces. 2014 Oct 1;122:38-45. doi: 10.1016/j.colsurfb.2014.05.025. Epub 2014 Jun 23.

PMID:
25016543
9.

Selective tumor necrosis factor receptor I blockade is antiinflammatory and reveals immunoregulatory role of tumor necrosis factor receptor II in collagen-induced arthritis.

McCann FE, Perocheau DP, Ruspi G, Blazek K, Davies ML, Feldmann M, Dean JL, Stoop AA, Williams RO.

Arthritis Rheumatol. 2014 Oct;66(10):2728-38. doi: 10.1002/art.38755.

PMID:
24965881
10.

Treg cell function in rheumatoid arthritis is compromised by ctla-4 promoter methylation resulting in a failure to activate the indoleamine 2,3-dioxygenase pathway.

Cribbs AP, Kennedy A, Penn H, Read JE, Amjadi P, Green P, Syed K, Manka SW, Brennan FM, Gregory B, Williams RO.

Arthritis Rheumatol. 2014 Sep;66(9):2344-54. doi: 10.1002/art.38715.

PMID:
24891289
11.

Characterization and pharmacokinetic analysis of crystalline versus amorphous rapamycin dry powder via pulmonary administration in rats.

Carvalho SR, Watts AB, Peters JI, Liu S, Hengsawas S, Escotet-Espinoza MS, Williams RO 3rd.

Eur J Pharm Biopharm. 2014 Sep;88(1):136-47. doi: 10.1016/j.ejpb.2014.05.008. Epub 2014 May 22.

PMID:
24859653
12.

In vitro and in vivo performance of dry powder inhalation formulations: comparison of particles prepared by thin film freezing and micronization.

Wang YB, Watts AB, Peters JI, Liu S, Batra A, Williams RO 3rd.

AAPS PharmSciTech. 2014 Aug;15(4):981-93. doi: 10.1208/s12249-014-0126-7. Epub 2014 May 14.

PMID:
24824172
13.

Solid lipid nanoparticle formulations of docetaxel prepared with high melting point triglycerides: in vitro and in vivo evaluation.

Naguib YW, Rodriguez BL, Li X, Hursting SD, Williams RO 3rd, Cui Z.

Mol Pharm. 2014 Apr 7;11(4):1239-49. doi: 10.1021/mp4006968. Epub 2014 Mar 12.

14.

Hot-melt extrusion--basic principles and pharmaceutical applications.

Lang B, McGinity JW, Williams RO 3rd.

Drug Dev Ind Pharm. 2014 Sep;40(9):1133-55. doi: 10.3109/03639045.2013.838577. Epub 2014 Feb 13. Review.

PMID:
24520867
15.

TNFR2 increases the sensitivity of ligand-induced activation of the p38 MAPK and NF-κB pathways and signals TRAF2 protein degradation in macrophages.

Ruspi G, Schmidt EM, McCann F, Feldmann M, Williams RO, Stoop AA, Dean JL.

Cell Signal. 2014 Apr;26(4):683-90. doi: 10.1016/j.cellsig.2013.12.009. Epub 2013 Dec 27.

PMID:
24378531
16.

Preparation of amorphous solid dispersions by rotary evaporation and KinetiSol Dispersing: approaches to enhance solubility of a poorly water-soluble gum extract.

Bennett RC, Brough C, Miller DA, O'Donnell KP, Keen JM, Hughey JR, Williams RO 3rd, McGinity JW.

Drug Dev Ind Pharm. 2015 Mar;41(3):382-97. doi: 10.3109/03639045.2013.866142. Epub 2013 Dec 16.

PMID:
24329130
17.

The impact of pulmonary diseases on the fate of inhaled medicines--a review.

Wang YB, Watts AB, Peters JI, Williams RO 3rd.

Int J Pharm. 2014 Jan 30;461(1-2):112-28. doi: 10.1016/j.ijpharm.2013.11.042. Epub 2013 Nov 27. Review.

PMID:
24291124
18.

Dissolution enhancement of itraconazole by hot-melt extrusion alone and the combination of hot-melt extrusion and rapid freezing--effect of formulation and processing variables.

Lang B, McGinity JW, Williams RO 3rd.

Mol Pharm. 2014 Jan 6;11(1):186-96. doi: 10.1021/mp4003706. Epub 2013 Dec 11.

PMID:
24283890
19.

Heat shock protein B1-deficient mice display impaired wound healing.

Crowe J, Aubareda A, McNamee K, Przybycien PM, Lu X, Williams RO, Bou-Gharios G, Saklatvala J, Dean JL.

PLoS One. 2013 Oct 15;8(10):e77383. doi: 10.1371/journal.pone.0077383. eCollection 2013.

20.
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