Wiggin GR[Author] - Search Results

Year	Number of Results
2002	1
2003	1
2005	2
2007	1
2014	1
2015	1
2019	1
2021	2
2023	1
2024	0

1

The adhesion GPCR Adgrg6 (Gpr126): Insights from the zebrafish model.

Baxendale S, Asad A, Shahidan NO, Wiggin GR, Whitfield TT. Baxendale S, et al. Among authors: wiggin gr. Genesis. 2021 Apr;59(4):e23417. doi: 10.1002/dvg.23417. Epub 2021 Mar 18. Genesis. 2021. PMID: 33735533 Free article. Review.

2

A screen of pharmacologically active compounds to identify modulators of the Adgrg6/Gpr126 signalling pathway in zebrafish embryos.

Asad A, Shahidan NO, de la Vega de León A, Wiggin GR, Whitfield TT, Baxendale S. Asad A, et al. Among authors: wiggin gr. Basic Clin Pharmacol Toxicol. 2023 Oct;133(4):364-377. doi: 10.1111/bcpt.13923. Epub 2023 Jul 16. Basic Clin Pharmacol Toxicol. 2023. PMID: 37394692 Free PMC article.

3

Polarity proteins in axon specification and synaptogenesis.

Wiggin GR, Fawcett JP, Pawson T. Wiggin GR, et al. Dev Cell. 2005 Jun;8(6):803-16. doi: 10.1016/j.devcel.2005.05.007. Dev Cell. 2005. PMID: 15935771 Free article. Review.

4

Identification of compounds that rescue otic and myelination defects in the zebrafish adgrg6 (gpr126) mutant.

Diamantopoulou E, Baxendale S, de la Vega de León A, Asad A, Holdsworth CJ, Abbas L, Gillet VJ, Wiggin GR, Whitfield TT. Diamantopoulou E, et al. Among authors: wiggin gr. Elife. 2019 Jun 10;8:e44889. doi: 10.7554/eLife.44889. Elife. 2019. PMID: 31180326 Free PMC article.

5

Functional impact of intramolecular cleavage and dissociation of adhesion G protein-coupled receptor GPR133 (ADGRD1) on canonical signaling.

Frenster JD, Stephan G, Ravn-Boess N, Bready D, Wilcox J, Kieslich B, Wilde C, Sträter N, Wiggin GR, Liebscher I, Schöneberg T, Placantonakis DG. Frenster JD, et al. Among authors: wiggin gr. J Biol Chem. 2021 Jan-Jun;296:100798. doi: 10.1016/j.jbc.2021.100798. Epub 2021 May 20. J Biol Chem. 2021. PMID: 34022221 Free PMC article.

6

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.

Doré AS, Okrasa K, Patel JC, Serrano-Vega M, Bennett K, Cooke RM, Errey JC, Jazayeri A, Khan S, Tehan B, Weir M, Wiggin GR, Marshall FH. Doré AS, et al. Among authors: wiggin gr. Nature. 2014 Jul 31;511(7511):557-62. doi: 10.1038/nature13396. Epub 2014 Jul 6. Nature. 2014. PMID: 25042998

7

MSK regulate TCR-induced CREB phosphorylation but not immediate early gene transcription.

Kaiser M, Wiggin GR, Lightfoot K, Arthur JS, Macdonald A. Kaiser M, et al. Among authors: wiggin gr. Eur J Immunol. 2007 Sep;37(9):2583-95. doi: 10.1002/eji.200636606. Eur J Immunol. 2007. PMID: 17668895 Free article.

8

MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14.

Soloaga A, Thomson S, Wiggin GR, Rampersaud N, Dyson MH, Hazzalin CA, Mahadevan LC, Arthur JS. Soloaga A, et al. Among authors: wiggin gr. EMBO J. 2003 Jun 2;22(11):2788-97. doi: 10.1093/emboj/cdg273. EMBO J. 2003. PMID: 12773393 Free PMC article.

9

MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts.

Wiggin GR, Soloaga A, Foster JM, Murray-Tait V, Cohen P, Arthur JS. Wiggin GR, et al. Mol Cell Biol. 2002 Apr;22(8):2871-81. doi: 10.1128/MCB.22.8.2871-2881.2002. Mol Cell Biol. 2002. PMID: 11909979 Free PMC article.

10

Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu5 Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile).

Christopher JA, Aves SJ, Bennett KA, Doré AS, Errey JC, Jazayeri A, Marshall FH, Okrasa K, Serrano-Vega MJ, Tehan BG, Wiggin GR, Congreve M. Christopher JA, et al. Among authors: wiggin gr. J Med Chem. 2015 Aug 27;58(16):6653-64. doi: 10.1021/acs.jmedchem.5b00892. Epub 2015 Aug 12. J Med Chem. 2015. PMID: 26225459

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