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Results: 1 to 20 of 22

1.

Treatment of Niemann--pick type C disease by histone deacetylase inhibitors.

Helquist P, Maxfield FR, Wiech NL, Wiest O.

Neurotherapeutics. 2013 Oct;10(4):688-97. doi: 10.1007/s13311-013-0217-2. Review.

PMID:
24048860
[PubMed - indexed for MEDLINE]
2.

Secondary preventive medication persistence and adherence 1 year after stroke.

Bushnell CD, Olson DM, Zhao X, Pan W, Zimmer LO, Goldstein LB, Alberts MJ, Fagan SC, Fonarow GC, Johnston SC, Kidwell C, Labresh KA, Ovbiagele B, Schwamm L, Peterson ED; AVAIL Investigators.

Neurology. 2011 Sep 20;77(12):1182-90. doi: 10.1212/WNL.0b013e31822f0423. Epub 2011 Sep 7.

PMID:
21900638
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Inhibition of histone deacetylases: a pharmacological approach to the treatment of non-cancer disorders.

Wiech NL, Fisher JF, Helquist P, Wiest O.

Curr Top Med Chem. 2009;9(3):257-71. Review.

PMID:
19355990
[PubMed - indexed for MEDLINE]
4.

Toward selective histone deacetylase inhibitor design: homology modeling, docking studies, and molecular dynamics simulations of human class I histone deacetylases.

Wang DF, Helquist P, Wiech NL, Wiest O.

J Med Chem. 2005 Nov 3;48(22):6936-47.

PMID:
16250652
[PubMed - indexed for MEDLINE]
5.

On the function of the 14 A long internal cavity of histone deacetylase-like protein: implications for the design of histone deacetylase inhibitors.

Wang DF, Wiest O, Helquist P, Lan-Hargest HY, Wiech NL.

J Med Chem. 2004 Jun 17;47(13):3409-17.

PMID:
15189037
[PubMed - indexed for MEDLINE]
6.

QSAR studies of PC-3 cell line inhibition activity of TSA and SAHA-like hydroxamic acids.

Wang DF, Wiest O, Helquist P, Lan-Hargest HY, Wiech NL.

Bioorg Med Chem Lett. 2004 Feb 9;14(3):707-11.

PMID:
14741273
[PubMed - indexed for MEDLINE]
7.

6,7-Dihydro-5-[[(cis-2-hydroxy-trans-3-phenoxycyclopentyl)amino] methyl]-2-methylbenzo[b]thiophen-4(5H)-one: a novel alpha 1-adrenergic receptor antagonist and renal vasodilator.

McCarthy JR, Zimmerman MB, Trepanier DL, LeTourneau ME, Wiedeman PE, Whitten JP, Broersma RJ, Shea PJ, Wiech NL, Huffman JC.

J Med Chem. 1985 Sep;28(9):1142-5. No abstract available.

PMID:
2863377
[PubMed - indexed for MEDLINE]
8.

Potent enhancement of [3H]nitrendipine binding in rat cerebral cortical and cardiac homogenates: a putative mechanism for the action of MDL 12,330A.

Lee HR, Jaros JA, Roeske WR, Wiech NL, Ursillo R, Yamamura HI.

J Pharmacol Exp Ther. 1985 Jun;233(3):611-6.

PMID:
3159884
[PubMed - indexed for MEDLINE]
9.

Absence of an effect of terfenadine on guinea pig brain histamine H1-receptors in vivo determined by receptor binding techniques.

Wiech NL, Martin JS.

Arzneimittelforschung. 1982;32(9a):1167-70.

PMID:
6817763
[PubMed - indexed for MEDLINE]
10.

Rapid desensitization of central beta-receptors and up-regulation of alpha 2-receptors following antidepressant treatment.

Reisine T, Johnson R, Wiech N, Ursillo R, Yamamura HI.

Adv Biochem Psychopharmacol. 1982;31:63-7. No abstract available.

PMID:
6282066
[PubMed - indexed for MEDLINE]
11.

Effects of desipramine and yohimbine on alpha 2- and beta-adrenoreceptor sensitivity.

Johnson RW, Reisine T, Spotnitz S, Wiech N, Ursillo R, Yamamura HI.

Eur J Pharmacol. 1980 Oct 3;67(1):123-7.

PMID:
6252022
[PubMed - indexed for MEDLINE]
12.

Effects of combined administration of amphetamine and iprindole on brain adrenergic receptors.

Reisine TD, U'Prichard DC, Wiech NL, Ursillo RC, Yamamura HI.

Brain Res. 1980 Apr 28;188(2):587-92. No abstract available.

PMID:
6245760
[PubMed - indexed for MEDLINE]
13.

Acceleration of desipramine-induced decrease of rat corticocerebral beta-adrenergic receptors by yohimbine.

Wiech NL, Ursillo RC.

Commun Psychopharmacol. 1980;4(2):95-100. No abstract available.

PMID:
6253232
[PubMed - indexed for MEDLINE]
14.

Hypoglycemic alpha-cycloalkylphenylmehtyl, furanalkyl, and thiophenealkyl lactamimides.

Grisar JM, Claxton GP, Wiech NL.

J Med Chem. 1976 Mar;19(3):365-9.

PMID:
1255659
[PubMed - indexed for MEDLINE]
15.

Glycogenolytic effect of adipose tissue extract.

Siegel BW, Blohm TR, Wiech NL.

Experientia. 1975 Jan 15;31(1):98-9. No abstract available.

PMID:
1112336
[PubMed - indexed for MEDLINE]
16.

Cyclization of lactamimide ketones to imidazo(1,2-a)-azacycloalkanes with hypoglycemic activity.

Claxton GP, Grisar JM, Wiech NL.

J Med Chem. 1974 Mar;17(3):364-7. No abstract available.

PMID:
4811238
[PubMed - indexed for MEDLINE]
17.

Benzhydryl and fluorenyl lactamimides with hypoglycemic, diuretic, blood platelet aggregation inhibitory, and antiinflammatory activities.

Grisar JM, Claxton GP, Wiech NL, Lucas RW, MacKenzie RD, Goldstein S.

J Med Chem. 1973 Aug;16(8):885-93. No abstract available.

PMID:
4147685
[PubMed - indexed for MEDLINE]
18.

Hypoglycemic cycloalkyl lactamimides.

Grisar JM, Claxton GP, Carr AA, Wiech NL.

J Med Chem. 1973 Jun;16(6):679-83. No abstract available.

PMID:
4715001
[PubMed - indexed for MEDLINE]
19.

Hypocholesterolemic indole-2-carboxylic acids.

Kariya T, Grisar JM, Wiech NL, Blohm TR.

J Med Chem. 1972 Jun;15(6):659-62. No abstract available.

PMID:
5030934
[PubMed - indexed for MEDLINE]
20.

Absorption and metabolism of dietary triglycerides in germfree and conventional rats.

Wiech NL, Hamilton JG, Miller ON.

J Nutr. 1967 Nov;93(3):324-30. No abstract available.

PMID:
6079870
[PubMed - indexed for MEDLINE]
Free Article

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