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Results: 1 to 20 of 78

1.

Revised risk estimation and treatment stratification of low- and intermediate-risk neuroblastoma patients by integrating clinical and molecular prognostic markers.

Oberthuer A, Juraeva D, Hero B, Volland R, Carolina S, Schmidt R, Faldum A, Kahlert Y, Engesser A, Asgharzadeh S, Seeger RC, Ohira M, Nakagawara A, Scaruffi P, Tonini GP, Janoueix-Lerosey I, Delattre O, Schleiermacher G, Vandesompele J, Speleman F, Noguera R, Piqueras M, Benard J, Valent A, Avigad S, Yaniv I, Grundy RG, Ortmann M, Shao C, Schwab M, Eils R, Simon T, Theissen J, Berthold F, Westermann F, Brors B, Fischer M.

Clin Cancer Res. 2014 Sep 17. pii: clincanres.0817.2014. [Epub ahead of print]

PMID:
25231397
[PubMed - as supplied by publisher]
2.

A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies.

Althoff K, Beckers A, Bell E, Nortmeyer M, Thor T, Sprüssel A, Lindner S, De Preter K, Florin A, Heukamp LC, Klein-Hitpass L, Astrahantseff K, Kumps C, Speleman F, Eggert A, Westermann F, Schramm A, Schulte JH.

Oncogene. 2014 Sep 1. doi: 10.1038/onc.2014.269. [Epub ahead of print]

PMID:
25174395
[PubMed - as supplied by publisher]
3.

p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas.

Dreidax D, Bannert S, Henrich KO, Schröder C, Bender S, Oakes CC, Lindner S, Schulte JH, Duffy D, Schwarzl T, Saadati M, Ehemann V, Benner A, Pfister S, Fischer M, Westermann F.

Hum Mol Genet. 2014 Aug 7. pii: ddu406. [Epub ahead of print]

PMID:
25104850
[PubMed - as supplied by publisher]
4.

NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma.

Fiaschetti G, Schroeder C, Castelletti D, Arcaro A, Westermann F, Baumgartner M, Shalaby T, Grotzer MA.

Acta Neuropathol Commun. 2014 Apr 7;2:39. doi: 10.1186/2051-5960-2-39.

PMID:
24708907
[PubMed - in process]
Free PMC Article
5.

Disruption of foraging by a dominant invasive species to decrease its competitive ability.

Westermann FL, Suckling DM, Lester PJ.

PLoS One. 2014 Mar 4;9(3):e90173. doi: 10.1371/journal.pone.0090173. eCollection 2014.

PMID:
24594633
[PubMed - in process]
Free PMC Article
6.

Testing of SNS-032 in a Panel of Human Neuroblastoma Cell Lines with Acquired Resistance to a Broad Range of Drugs.

Löschmann N, Michaelis M, Rothweiler F, Zehner R, Cinatl J, Voges Y, Sharifi M, Riecken K, Meyer J, von Deimling A, Fichtner I, Ghafourian T, Westermann F, Cinatl J Jr.

Transl Oncol. 2013 Dec 1;6(6):685-96. eCollection 2013 Dec 1.

PMID:
24466371
[PubMed]
Free PMC Article
7.

GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.

Fabian J, Lodrini M, Oehme I, Schier MC, Thole TM, Hielscher T, Kopp-Schneider A, Opitz L, Capper D, von Deimling A, Wiegand I, Milde T, Mahlknecht U, Westermann F, Popanda O, Roels F, Hero B, Berthold F, Fischer M, Kulozik AE, Witt O, Deubzer HE.

Cancer Res. 2014 May 1;74(9):2604-16. doi: 10.1158/0008-5472.CAN-13-1904. Epub 2014 Jan 13.

PMID:
24419085
[PubMed - indexed for MEDLINE]
8.

Cell survival signalling through PPARδ and arachidonic acid metabolites in neuroblastoma.

Bell E, Ponthan F, Whitworth C, Westermann F, Thomas H, Redfern CP.

PLoS One. 2013 Jul 9;8(7):e68859. doi: 10.1371/journal.pone.0068859. Print 2013.

PMID:
23874790
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.

Lodrini M, Oehme I, Schroeder C, Milde T, Schier MC, Kopp-Schneider A, Schulte JH, Fischer M, De Preter K, Pattyn F, Castoldi M, Muckenthaler MU, Kulozik AE, Westermann F, Witt O, Deubzer HE.

Nucleic Acids Res. 2013 Jul;41(12):6018-33. doi: 10.1093/nar/gkt346. Epub 2013 Apr 26.

PMID:
23625969
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Stronger prognostic power of the CpG island methylator phenotype than methylation of individual genes in neuroblastomas.

Asada K, Watanabe N, Nakamura Y, Ohira M, Westermann F, Schwab M, Nakagawara A, Ushijima T.

Jpn J Clin Oncol. 2013 Jun;43(6):641-5. doi: 10.1093/jjco/hyt058. Epub 2013 Apr 25.

PMID:
23619990
[PubMed - indexed for MEDLINE]
Free Article
11.

Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma.

Kocak H, Ackermann S, Hero B, Kahlert Y, Oberthuer A, Juraeva D, Roels F, Theissen J, Westermann F, Deubzer H, Ehemann V, Brors B, Odenthal M, Berthold F, Fischer M.

Cell Death Dis. 2013 Apr 11;4:e586. doi: 10.1038/cddis.2013.84.

PMID:
23579273
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

CDK4 inhibition restores G(1)-S arrest in MYCN-amplified neuroblastoma cells in the context of doxorubicin-induced DNA damage.

Gogolin S, Ehemann V, Becker G, Brueckner LM, Dreidax D, Bannert S, Nolte I, Savelyeva L, Bell E, Westermann F.

Cell Cycle. 2013 Apr 1;12(7):1091-104. doi: 10.4161/cc.24091. Epub 2013 Mar 5.

PMID:
23462184
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction.

Carotenuto M, Pedone E, Diana D, de Antonellis P, Džeroski S, Marino N, Navas L, Di Dato V, Scoppettuolo MN, Cimmino F, Correale S, Pirone L, Monti SM, Bruder E, Zenko B, Slavkov I, Pastorino F, Ponzoni M, Schulte JH, Schramm A, Eggert A, Westermann F, Arrigoni G, Accordi B, Basso G, Saviano M, Fattorusso R, Zollo M.

Sci Rep. 2013;3:1351. doi: 10.1038/srep01351.

PMID:
23448979
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Low p14ARF expression in neuroblastoma cells is associated with repressed histone mark status, and enforced expression induces growth arrest and apoptosis.

Dreidax D, Gogolin S, Schroeder C, Muth D, Brueckner LM, Hess EM, Zapatka M, Theißen J, Fischer M, Ehemann V, Schwab M, Savelyeva L, Westermann F.

Hum Mol Genet. 2013 May 1;22(9):1735-45. doi: 10.1093/hmg/ddt020. Epub 2013 Jan 23.

PMID:
23343716
[PubMed - indexed for MEDLINE]
Free Article
15.

Focal DNA copy number changes in neuroblastoma target MYCN regulated genes.

Kumps C, Fieuw A, Mestdagh P, Menten B, Lefever S, Pattyn F, De Brouwer S, Sante T, Schulte JH, Schramm A, Van Roy N, Van Maerken T, Noguera R, Combaret V, Devalck C, Westermann F, Laureys G, Eggert A, Vandesompele J, De Preter K, Speleman F.

PLoS One. 2013;8(1):e52321. doi: 10.1371/journal.pone.0052321. Epub 2013 Jan 4.

PMID:
23308108
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Time-lapse imaging of neuroblastoma cells to determine cell fate upon gene knockdown.

Batra R, Harder N, Gogolin S, Diessl N, Soons Z, Jäger-Schmidt C, Lawerenz C, Eils R, Rohr K, Westermann F, König R.

PLoS One. 2012;7(12):e50988. doi: 10.1371/journal.pone.0050988. Epub 2012 Dec 12.

PMID:
23251412
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

MYCN-mediated overexpression of mitotic spindle regulatory genes and loss of p53-p21 function jointly support the survival of tetraploid neuroblastoma cells.

Gogolin S, Batra R, Harder N, Ehemann V, Paffhausen T, Diessl N, Sagulenko V, Benner A, Gade S, Nolte I, Rohr K, König R, Westermann F.

Cancer Lett. 2013 Apr 30;331(1):35-45. doi: 10.1016/j.canlet.2012.11.028. Epub 2012 Nov 24.

PMID:
23186832
[PubMed - indexed for MEDLINE]
18.

1p36 tumor suppression--a matter of dosage?

Henrich KO, Schwab M, Westermann F.

Cancer Res. 2012 Dec 1;72(23):6079-88. doi: 10.1158/0008-5472.CAN-12-2230. Epub 2012 Nov 20. Review.

PMID:
23172308
[PubMed - indexed for MEDLINE]
Free Article
19.

RNA interference screening identifies a novel role for autocrine fibroblast growth factor signaling in neuroblastoma chemoresistance.

Salm F, Cwiek P, Ghosal A, Lucia Buccarello A, Largey F, Wotzkow C, Höland K, Styp-Rekowska B, Djonov V, Zlobec I, Bodmer N, Gross N, Westermann F, Schäfer SC, Arcaro A.

Oncogene. 2013 Aug 22;32(34):3944-53. doi: 10.1038/onc.2012.416. Epub 2012 Oct 1.

PMID:
23027129
[PubMed - indexed for MEDLINE]
20.

Biological and clinical heterogeneity of MYCN-amplified medulloblastoma.

Korshunov A, Remke M, Kool M, Hielscher T, Northcott PA, Williamson D, Pfaff E, Witt H, Jones DT, Ryzhova M, Cho YJ, Wittmann A, Benner A, Weiss WA, von Deimling A, Scheurlen W, Kulozik AE, Clifford SC, Peter Collins V, Westermann F, Taylor MD, Lichter P, Pfister SM.

Acta Neuropathol. 2012 Apr;123(4):515-27. doi: 10.1007/s00401-011-0918-8. Epub 2011 Dec 9.

PMID:
22160402
[PubMed - indexed for MEDLINE]

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