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Results: 1 to 20 of 64

1.

Matrix metalloproteinase 9-mediated shedding of syndecan 4 in response to tumor necrosis factor α: a contributor to endothelial cell glycocalyx dysfunction.

Ramnath R, Foster RR, Qiu Y, Cope G, Butler MJ, Salmon AH, Mathieson PW, Coward RJ, Welsh GI, Satchell SC.

FASEB J. 2014 Aug 13. pii: fj.14-252221. [Epub ahead of print]

PMID:
25122554
[PubMed - as supplied by publisher]
2.

High fat feeding promotes obesity and renal inflammation and protects against post cardiopulmonary bypass acute kidney injury in swine.

Sleeman P, Patel NN, Lin H, Walkden GJ, Ray P, Welsh GI, Satchell SC, Murphy GJ.

Crit Care. 2013 Oct 31;17(5):R262. [Epub ahead of print]

PMID:
24172587
[PubMed - as supplied by publisher]
Free PMC Article
3.

Glycosaminoglycan regulation by VEGFA and VEGFC of the glomerular microvascular endothelial cell glycocalyx in vitro.

Foster RR, Armstrong L, Baker S, Wong DW, Wylie EC, Ramnath R, Jenkins R, Singh A, Steadman R, Welsh GI, Mathieson PW, Satchell SC.

Am J Pathol. 2013 Aug;183(2):604-16. doi: 10.1016/j.ajpath.2013.04.019. Epub 2013 Jun 12.

PMID:
23770346
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Insulin directly stimulates VEGF-A production in the glomerular podocyte.

Hale LJ, Hurcombe J, Lay A, Santamaría B, Valverde AM, Saleem MA, Mathieson PW, Welsh GI, Coward RJ.

Am J Physiol Renal Physiol. 2013 Jul 15;305(2):F182-8. doi: 10.1152/ajprenal.00548.2012. Epub 2013 May 22.

PMID:
23698113
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Reactive oxygen species modulate the barrier function of the human glomerular endothelial glycocalyx.

Singh A, Ramnath RD, Foster RR, Wylie EC, Fridén V, Dasgupta I, Haraldsson B, Welsh GI, Mathieson PW, Satchell SC.

PLoS One. 2013;8(2):e55852. doi: 10.1371/journal.pone.0055852. Epub 2013 Feb 14.

PMID:
23457483
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Active proteases in nephrotic plasma lead to a podocin-dependent phosphorylation of VASP in podocytes via protease activated receptor-1.

Harris JJ, McCarthy HJ, Ni L, Wherlock M, Kang H, Wetzels JF, Welsh GI, Saleem MA.

J Pathol. 2013 Apr;229(5):660-71. doi: 10.1002/path.4149. Epub 2013 Feb 22.

PMID:
23436459
[PubMed - indexed for MEDLINE]
7.

Simultaneous sequencing of 24 genes associated with steroid-resistant nephrotic syndrome.

McCarthy HJ, Bierzynska A, Wherlock M, Ognjanovic M, Kerecuk L, Hegde S, Feather S, Gilbert RD, Krischock L, Jones C, Sinha MD, Webb NJ, Christian M, Williams MM, Marks S, Koziell A, Welsh GI, Saleem MA; RADAR the UK SRNS Study Group.

Clin J Am Soc Nephrol. 2013 Apr;8(4):637-48. doi: 10.2215/CJN.07200712. Epub 2013 Jan 24.

PMID:
23349334
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Insulin-like growth factor-II is produced by, signals to and is an important survival factor for the mature podocyte in man and mouse.

Hale LJ, Welsh GI, Perks CM, Hurcombe JA, Moore S, Hers I, Saleem MA, Mathieson PW, Murphy AJ, Jeansson M, Holly JM, Hardouin SN, Coward RJ.

J Pathol. 2013 May;230(1):95-106. doi: 10.1002/path.4165. Epub 2013 Mar 21.

PMID:
23299523
[PubMed - indexed for MEDLINE]
9.

Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes.

Slater SC, Ramnath RD, Uttridge K, Saleem MA, Cahill PA, Mathieson PW, Welsh GI, Satchell SC.

Int J Biochem Cell Biol. 2012 Sep;44(9):1482-90. doi: 10.1016/j.biocel.2012.05.020. Epub 2012 Jun 6.

PMID:
22683691
[PubMed - indexed for MEDLINE]
10.

IQGAP1 interacts with components of the slit diaphragm complex in podocytes and is involved in podocyte migration and permeability in vitro.

Rigothier C, Auguste P, Welsh GI, Lepreux S, Deminière C, Mathieson PW, Saleem MA, Ripoche J, Combe C.

PLoS One. 2012;7(5):e37695. doi: 10.1371/journal.pone.0037695. Epub 2012 May 25.

PMID:
22662192
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

VEGF and sVEGFR-1 in malignant pleural effusions: association with survival and pleurodesis outcomes.

Hooper CE, Elvers KT, Welsh GI, Millar AB, Maskell NA.

Lung Cancer. 2012 Aug;77(2):443-9. doi: 10.1016/j.lungcan.2012.03.006. Epub 2012 Apr 7.

PMID:
22487430
[PubMed - indexed for MEDLINE]
12.

WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing.

Amin EM, Oltean S, Hua J, Gammons MV, Hamdollah-Zadeh M, Welsh GI, Cheung MK, Ni L, Kase S, Rennel ES, Symonds KE, Nowak DG, Royer-Pokora B, Saleem MA, Hagiwara M, Schumacher VA, Harper SJ, Hinton DR, Bates DO, Ladomery MR.

Cancer Cell. 2011 Dec 13;20(6):768-80. doi: 10.1016/j.ccr.2011.10.016.

PMID:
22172722
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The podocyte cytoskeleton--key to a functioning glomerulus in health and disease.

Welsh GI, Saleem MA.

Nat Rev Nephrol. 2011 Oct 25;8(1):14-21. doi: 10.1038/nrneph.2011.151. Review.

PMID:
22025085
[PubMed - indexed for MEDLINE]
14.

Phosphodiesterase-5 inhibition prevents postcardiopulmonary bypass acute kidney injury in swine.

Patel NN, Lin H, Toth T, Jones C, Ray P, Welsh GI, Satchell SC, Sleeman P, Angelini GD, Murphy GJ.

Ann Thorac Surg. 2011 Dec;92(6):2168-76. doi: 10.1016/j.athoracsur.2011.07.002. Epub 2011 Oct 8.

PMID:
21983073
[PubMed - indexed for MEDLINE]
15.

Acute laminar shear stress reversibly increases human glomerular endothelial cell permeability via activation of endothelial nitric oxide synthase.

Bevan HS, Slater SC, Clarke H, Cahill PA, Mathieson PW, Welsh GI, Satchell SC.

Am J Physiol Renal Physiol. 2011 Oct;301(4):F733-42. doi: 10.1152/ajprenal.00458.2010. Epub 2011 Jul 20.

PMID:
21775480
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

An in vitro model of the glomerular capillary wall using electrospun collagen nanofibres in a bioartificial composite basement membrane.

Slater SC, Beachley V, Hayes T, Zhang D, Welsh GI, Saleem MA, Mathieson PW, Wen X, Su B, Satchell SC.

PLoS One. 2011;6(6):e20802. doi: 10.1371/journal.pone.0020802. Epub 2011 Jun 24.

PMID:
21731625
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Establishment of conditionally immortalized human glomerular mesangial cells in culture, with unique migratory properties.

Sarrab RM, Lennon R, Ni L, Wherlock MD, Welsh GI, Saleem MA.

Am J Physiol Renal Physiol. 2011 Nov;301(5):F1131-8. doi: 10.1152/ajprenal.00589.2010. Epub 2011 Jun 8.

PMID:
21653636
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Reversal of anemia with allogenic RBC transfusion prevents post-cardiopulmonary bypass acute kidney injury in swine.

Patel NN, Lin H, Toth T, Welsh GI, Jones C, Ray P, Satchell SC, Sleeman P, Angelini GD, Murphy GJ.

Am J Physiol Renal Physiol. 2011 Sep;301(3):F605-14. doi: 10.1152/ajprenal.00145.2011. Epub 2011 Jun 8.

PMID:
21653630
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

High glucose causes dysfunction of the human glomerular endothelial glycocalyx.

Singh A, Fridén V, Dasgupta I, Foster RR, Welsh GI, Tooke JE, Haraldsson B, Mathieson PW, Satchell SC.

Am J Physiol Renal Physiol. 2011 Jan;300(1):F40-8. doi: 10.1152/ajprenal.00103.2010. Epub 2010 Oct 27.

PMID:
20980411
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Insulin signaling to the glomerular podocyte is critical for normal kidney function.

Welsh GI, Hale LJ, Eremina V, Jeansson M, Maezawa Y, Lennon R, Pons DA, Owen RJ, Satchell SC, Miles MJ, Caunt CJ, McArdle CA, Pavenstädt H, Tavaré JM, Herzenberg AM, Kahn CR, Mathieson PW, Quaggin SE, Saleem MA, Coward RJ.

Cell Metab. 2010 Oct 6;12(4):329-40. doi: 10.1016/j.cmet.2010.08.015.

PMID:
20889126
[PubMed - indexed for MEDLINE]
Free Article

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