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Results: 1 to 20 of 71


Clinical and Genetic Analysis of Patients with Cystinuria in the United Kingdom.

Rhodes HL, Yarram-Smith L, Rice SJ, Tabaksert A, Edwards N, Hartley A, Woodward MN, Smithson SL, Tomson C, Welsh GI, Williams M, Thwaites DT, Sayer JA, Coward RJ.

Clin J Am Soc Nephrol. 2015 May 11. pii: CJN.10981114. [Epub ahead of print]


Coinheritance of COL4A5 and MYO1E mutations accentuate the severity of kidney disease.

Lennon R, Stuart HM, Bierzynska A, Randles MJ, Kerr B, Hillman KA, Batra G, Campbell J, Storey H, Flinter FA, Koziell A, Welsh GI, Saleem MA, Webb NJ, Woolf AS.

Pediatr Nephrol. 2015 Mar 5. [Epub ahead of print]


Generating conditionally immortalised podocyte cell lines from wild-type mice.

Keir LS, Firth R, May C, Ni L, Welsh GI, Saleem MA.

Nephron. 2015;129(2):128-36.


Levamisole in steroid-sensitive nephrotic syndrome: usefulness in adult patients and laboratory insights into mechanisms of action via direct action on the kidney podocyte.

Jiang L, Dasgupta I, Hurcombe JA, Colyer HF, Mathieson PW, Welsh GI.

Clin Sci (Lond). 2015 Jun;128(12):883-93. doi: 10.1042/CS20140749.


A systems model of phosphorylation for inflammatory signaling events.

Sadreev II, Chen MZ, Welsh GI, Umezawa Y, Kotov NV, Valeyev NV.

PLoS One. 2014 Oct 21;9(10):e110913. doi: 10.1371/journal.pone.0110913. eCollection 2014.


Podocyte dedifferentiation: a specialized process for a specialized cell.

May CJ, Saleem M, Welsh GI.

Front Endocrinol (Lausanne). 2014 Oct 1;5:148. doi: 10.3389/fendo.2014.00148. eCollection 2014. Review.


Molecular and cellular events mediating glomerular podocyte dysfunction and depletion in diabetes mellitus.

Anil Kumar P, Welsh GI, Saleem MA, Menon RK.

Front Endocrinol (Lausanne). 2014 Sep 25;5:151. doi: 10.3389/fendo.2014.00151. eCollection 2014. Review.


Matrix metalloproteinase 9-mediated shedding of syndecan 4 in response to tumor necrosis factor α: a contributor to endothelial cell glycocalyx dysfunction.

Ramnath R, Foster RR, Qiu Y, Cope G, Butler MJ, Salmon AH, Mathieson PW, Coward RJ, Welsh GI, Satchell SC.

FASEB J. 2014 Nov;28(11):4686-99. doi: 10.1096/fj.14-252221. Epub 2014 Aug 13.


High fat feeding promotes obesity and renal inflammation and protects against post cardiopulmonary bypass acute kidney injury in swine.

Sleeman P, Patel NN, Lin H, Walkden GJ, Ray P, Welsh GI, Satchell SC, Murphy GJ.

Crit Care. 2013 Oct 31;17(5):R262. doi: 10.1186/cc13092.


Glycosaminoglycan regulation by VEGFA and VEGFC of the glomerular microvascular endothelial cell glycocalyx in vitro.

Foster RR, Armstrong L, Baker S, Wong DW, Wylie EC, Ramnath R, Jenkins R, Singh A, Steadman R, Welsh GI, Mathieson PW, Satchell SC.

Am J Pathol. 2013 Aug;183(2):604-16. doi: 10.1016/j.ajpath.2013.04.019. Epub 2013 Jun 12.


Insulin directly stimulates VEGF-A production in the glomerular podocyte.

Hale LJ, Hurcombe J, Lay A, Santamaría B, Valverde AM, Saleem MA, Mathieson PW, Welsh GI, Coward RJ.

Am J Physiol Renal Physiol. 2013 Jul 15;305(2):F182-8. doi: 10.1152/ajprenal.00548.2012. Epub 2013 May 22.


Reactive oxygen species modulate the barrier function of the human glomerular endothelial glycocalyx.

Singh A, Ramnath RD, Foster RR, Wylie EC, Fridén V, Dasgupta I, Haraldsson B, Welsh GI, Mathieson PW, Satchell SC.

PLoS One. 2013;8(2):e55852. doi: 10.1371/journal.pone.0055852. Epub 2013 Feb 14.


Active proteases in nephrotic plasma lead to a podocin-dependent phosphorylation of VASP in podocytes via protease activated receptor-1.

Harris JJ, McCarthy HJ, Ni L, Wherlock M, Kang H, Wetzels JF, Welsh GI, Saleem MA.

J Pathol. 2013 Apr;229(5):660-71. doi: 10.1002/path.4149. Epub 2013 Feb 22.


Simultaneous sequencing of 24 genes associated with steroid-resistant nephrotic syndrome.

McCarthy HJ, Bierzynska A, Wherlock M, Ognjanovic M, Kerecuk L, Hegde S, Feather S, Gilbert RD, Krischock L, Jones C, Sinha MD, Webb NJ, Christian M, Williams MM, Marks S, Koziell A, Welsh GI, Saleem MA; RADAR the UK SRNS Study Group.

Clin J Am Soc Nephrol. 2013 Apr;8(4):637-48. doi: 10.2215/CJN.07200712. Epub 2013 Jan 24.


Insulin-like growth factor-II is produced by, signals to and is an important survival factor for the mature podocyte in man and mouse.

Hale LJ, Welsh GI, Perks CM, Hurcombe JA, Moore S, Hers I, Saleem MA, Mathieson PW, Murphy AJ, Jeansson M, Holly JM, Hardouin SN, Coward RJ.

J Pathol. 2013 May;230(1):95-106. doi: 10.1002/path.4165. Epub 2013 Mar 21.


Chronic exposure to laminar shear stress induces Kruppel-like factor 2 in glomerular endothelial cells and modulates interactions with co-cultured podocytes.

Slater SC, Ramnath RD, Uttridge K, Saleem MA, Cahill PA, Mathieson PW, Welsh GI, Satchell SC.

Int J Biochem Cell Biol. 2012 Sep;44(9):1482-90. doi: 10.1016/j.biocel.2012.05.020. Epub 2012 Jun 6.


IQGAP1 interacts with components of the slit diaphragm complex in podocytes and is involved in podocyte migration and permeability in vitro.

Rigothier C, Auguste P, Welsh GI, Lepreux S, Deminière C, Mathieson PW, Saleem MA, Ripoche J, Combe C.

PLoS One. 2012;7(5):e37695. doi: 10.1371/journal.pone.0037695. Epub 2012 May 25.


VEGF and sVEGFR-1 in malignant pleural effusions: association with survival and pleurodesis outcomes.

Hooper CE, Elvers KT, Welsh GI, Millar AB, Maskell NA.

Lung Cancer. 2012 Aug;77(2):443-9. doi: 10.1016/j.lungcan.2012.03.006. Epub 2012 Apr 7.


WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing.

Amin EM, Oltean S, Hua J, Gammons MV, Hamdollah-Zadeh M, Welsh GI, Cheung MK, Ni L, Kase S, Rennel ES, Symonds KE, Nowak DG, Royer-Pokora B, Saleem MA, Hagiwara M, Schumacher VA, Harper SJ, Hinton DR, Bates DO, Ladomery MR.

Cancer Cell. 2011 Dec 13;20(6):768-80. doi: 10.1016/j.ccr.2011.10.016.


The podocyte cytoskeleton--key to a functioning glomerulus in health and disease.

Welsh GI, Saleem MA.

Nat Rev Nephrol. 2011 Oct 25;8(1):14-21. doi: 10.1038/nrneph.2011.151. Review.

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