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Items: 1 to 20 of 76

1.

Kinetic regulation of multi-ligand binding proteins.

Salakhieva DV, Sadreev II, Chen MZ, Umezawa Y, Evstifeev AI, Welsh GI, Kotov NV.

BMC Syst Biol. 2016 Apr 18;10:32. doi: 10.1186/s12918-016-0277-0.

2.

Disease causing mutations in inverted formin 2 regulate its binding to G-actin, F-actin capping protein (CapZ α-1) and profilin 2.

Rollason R, Wherlock M, Heath JA, Heesom KJ, Saleem MA, Welsh GI.

Biosci Rep. 2016 Jan 13;36(1):e00302. doi: 10.1042/BSR20150252.

3.

Carboxymethyl lysine induces EMT in podocytes through transcription factor ZEB2: Implications for podocyte depletion and proteinuria in diabetes mellitus.

Kumar PA, Welsh GI, Raghu G, Menon RK, Saleem MA, Reddy GB.

Arch Biochem Biophys. 2016 Jan 15;590:10-9. doi: 10.1016/j.abb.2015.11.003. Epub 2015 Nov 10.

PMID:
26550927
4.

Editorial: Podocyte Pathology and Nephropathy.

Lewko B, Welsh GI, Jankowski M.

Front Endocrinol (Lausanne). 2015 Sep 17;6:145. doi: 10.3389/fendo.2015.00145. eCollection 2015. No abstract available.

5.

IRS2 and PTEN are key molecules in controlling insulin sensitivity in podocytes.

Santamaria B, Marquez E, Lay A, Carew RM, González-Rodríguez Á, Welsh GI, Ni L, Hale LJ, Ortiz A, Saleem MA, Brazil DP, Coward RJ, Valverde ÁM.

Biochim Biophys Acta. 2015 Dec;1853(12):3224-34. doi: 10.1016/j.bbamcr.2015.09.020. Epub 2015 Sep 16. Erratum in: Biochim Biophys Acta. 2016 Apr;1863(4):786.

PMID:
26384875
6.

Clinical and genetic analysis of patients with cystinuria in the United Kingdom.

Rhodes HL, Yarram-Smith L, Rice SJ, Tabaksert A, Edwards N, Hartley A, Woodward MN, Smithson SL, Tomson C, Welsh GI, Williams M, Thwaites DT, Sayer JA, Coward RJ.

Clin J Am Soc Nephrol. 2015 Jul 7;10(7):1235-45. doi: 10.2215/CJN.10981114. Epub 2015 May 11.

PMID:
25964309
7.

Coinheritance of COL4A5 and MYO1E mutations accentuate the severity of kidney disease.

Lennon R, Stuart HM, Bierzynska A, Randles MJ, Kerr B, Hillman KA, Batra G, Campbell J, Storey H, Flinter FA, Koziell A, Welsh GI, Saleem MA, Webb NJ, Woolf AS.

Pediatr Nephrol. 2015 Sep;30(9):1459-65. doi: 10.1007/s00467-015-3067-9. Epub 2015 Mar 5.

8.

Generating conditionally immortalised podocyte cell lines from wild-type mice.

Keir LS, Firth R, May C, Ni L, Welsh GI, Saleem MA.

Nephron. 2015;129(2):128-36.

PMID:
25720381
9.

Levamisole in steroid-sensitive nephrotic syndrome: usefulness in adult patients and laboratory insights into mechanisms of action via direct action on the kidney podocyte.

Jiang L, Dasgupta I, Hurcombe JA, Colyer HF, Mathieson PW, Welsh GI.

Clin Sci (Lond). 2015 Jun;128(12):883-93. doi: 10.1042/CS20140749.

PMID:
25626449
10.

A systems model of phosphorylation for inflammatory signaling events.

Sadreev II, Chen MZ, Welsh GI, Umezawa Y, Kotov NV, Valeyev NV.

PLoS One. 2014 Oct 21;9(10):e110913. doi: 10.1371/journal.pone.0110913. eCollection 2014.

11.

Podocyte dedifferentiation: a specialized process for a specialized cell.

May CJ, Saleem M, Welsh GI.

Front Endocrinol (Lausanne). 2014 Oct 1;5:148. doi: 10.3389/fendo.2014.00148. eCollection 2014. Review.

12.

Molecular and cellular events mediating glomerular podocyte dysfunction and depletion in diabetes mellitus.

Anil Kumar P, Welsh GI, Saleem MA, Menon RK.

Front Endocrinol (Lausanne). 2014 Sep 25;5:151. doi: 10.3389/fendo.2014.00151. eCollection 2014. Review.

13.

Matrix metalloproteinase 9-mediated shedding of syndecan 4 in response to tumor necrosis factor α: a contributor to endothelial cell glycocalyx dysfunction.

Ramnath R, Foster RR, Qiu Y, Cope G, Butler MJ, Salmon AH, Mathieson PW, Coward RJ, Welsh GI, Satchell SC.

FASEB J. 2014 Nov;28(11):4686-99. doi: 10.1096/fj.14-252221. Epub 2014 Aug 13.

14.

High fat feeding promotes obesity and renal inflammation and protects against post cardiopulmonary bypass acute kidney injury in swine.

Sleeman P, Patel NN, Lin H, Walkden GJ, Ray P, Welsh GI, Satchell SC, Murphy GJ.

Crit Care. 2013 Oct 31;17(5):R262. doi: 10.1186/cc13092.

15.

Glycosaminoglycan regulation by VEGFA and VEGFC of the glomerular microvascular endothelial cell glycocalyx in vitro.

Foster RR, Armstrong L, Baker S, Wong DW, Wylie EC, Ramnath R, Jenkins R, Singh A, Steadman R, Welsh GI, Mathieson PW, Satchell SC.

Am J Pathol. 2013 Aug;183(2):604-16. doi: 10.1016/j.ajpath.2013.04.019. Epub 2013 Jun 12.

16.

Insulin directly stimulates VEGF-A production in the glomerular podocyte.

Hale LJ, Hurcombe J, Lay A, Santamaría B, Valverde AM, Saleem MA, Mathieson PW, Welsh GI, Coward RJ.

Am J Physiol Renal Physiol. 2013 Jul 15;305(2):F182-8. doi: 10.1152/ajprenal.00548.2012. Epub 2013 May 22.

17.

Reactive oxygen species modulate the barrier function of the human glomerular endothelial glycocalyx.

Singh A, Ramnath RD, Foster RR, Wylie EC, Fridén V, Dasgupta I, Haraldsson B, Welsh GI, Mathieson PW, Satchell SC.

PLoS One. 2013;8(2):e55852. doi: 10.1371/journal.pone.0055852. Epub 2013 Feb 14.

18.

Active proteases in nephrotic plasma lead to a podocin-dependent phosphorylation of VASP in podocytes via protease activated receptor-1.

Harris JJ, McCarthy HJ, Ni L, Wherlock M, Kang H, Wetzels JF, Welsh GI, Saleem MA.

J Pathol. 2013 Apr;229(5):660-71. doi: 10.1002/path.4149. Epub 2013 Feb 22.

PMID:
23436459
19.

Simultaneous sequencing of 24 genes associated with steroid-resistant nephrotic syndrome.

McCarthy HJ, Bierzynska A, Wherlock M, Ognjanovic M, Kerecuk L, Hegde S, Feather S, Gilbert RD, Krischock L, Jones C, Sinha MD, Webb NJ, Christian M, Williams MM, Marks S, Koziell A, Welsh GI, Saleem MA; RADAR the UK SRNS Study Group.

Clin J Am Soc Nephrol. 2013 Apr;8(4):637-48. doi: 10.2215/CJN.07200712. Epub 2013 Jan 24.

20.

Insulin-like growth factor-II is produced by, signals to and is an important survival factor for the mature podocyte in man and mouse.

Hale LJ, Welsh GI, Perks CM, Hurcombe JA, Moore S, Hers I, Saleem MA, Mathieson PW, Murphy AJ, Jeansson M, Holly JM, Hardouin SN, Coward RJ.

J Pathol. 2013 May;230(1):95-106. doi: 10.1002/path.4165. Epub 2013 Mar 21.

PMID:
23299523
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