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Results: 1 to 20 of 154

1.

A HARE Link Domain N-glycan is required for ERK and NF-κB signaling in response to the uptake of hyaluronan but not heparin, dermatan sulfate or acetylated lDL.

Pandy MS, Weigel PH.

J Biol Chem. 2014 Jun 18. pii: jbc.M114.565846. [Epub ahead of print]

PMID:
24942734
[PubMed - as supplied by publisher]
Free Article
3.

Methods for measuring Class I membrane-bound hyaluronan synthase activity.

Weigel PH, Padgett-McCue AJ, Baggenstoss BA.

Methods Mol Biol. 2013;1022:229-47. doi: 10.1007/978-1-62703-465-4_18.

PMID:
23765666
[PubMed - indexed for MEDLINE]
4.

The hyaluronan receptor for endocytosis (HARE) activates NF-κB-mediated gene expression in response to 40-400-kDa, but not smaller or larger, hyaluronans.

Pandey MS, Baggenstoss BA, Washburn J, Harris EN, Weigel PH.

J Biol Chem. 2013 May 17;288(20):14068-79. doi: 10.1074/jbc.M112.442889. Epub 2013 Mar 24.

PMID:
23530033
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Digestion products of the PH20 hyaluronidase inhibit remyelination.

Preston M, Gong X, Su W, Matsumoto SG, Banine F, Winkler C, Foster S, Xing R, Struve J, Dean J, Baggenstoss B, Weigel PH, Montine TJ, Back SA, Sherman LS.

Ann Neurol. 2013 Feb;73(2):266-80. doi: 10.1002/ana.23788. Epub 2013 Mar 5.

PMID:
23463525
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Tumor necrosis factor-stimulated gene-6 (TSG-6) amplifies hyaluronan synthesis by airway smooth muscle cells.

Lauer ME, Cheng G, Swaidani S, Aronica MA, Weigel PH, Hascall VC.

J Biol Chem. 2013 Jan 4;288(1):423-31. doi: 10.1074/jbc.M112.389882. Epub 2012 Nov 5.

PMID:
23129777
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Hyaluronan turnover and hypoxic brown adipocytic differentiation are co-localized with ossification in calcified human aortic valves.

Stephens EH, Saltarrelli JG Jr, Balaoing LR, Baggett LS, Nandi I, Anderson KM, Morrisett JD, Reardon MJ, Simpson MA, Weigel PH, Olmsted-Davis EA, Davis AR, Grande-Allen KJ.

Pathol Res Pract. 2012 Nov 15;208(11):642-50. doi: 10.1016/j.prp.2012.08.001. Epub 2012 Sep 25.

PMID:
23017666
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Hyaluronan synthase polymerizing activity and control of product size are discrete enzyme functions that can be uncoupled by mutagenesis of conserved cysteines.

Weigel PH, Baggenstoss BA.

Glycobiology. 2012 Oct;22(10):1302-10. doi: 10.1093/glycob/cws102. Epub 2012 Jun 27.

PMID:
22745284
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Hyaluronan synthase mediates dye translocation across liposomal membranes.

Medina AP, Lin J, Weigel PH.

BMC Biochem. 2012 Jan 25;13:2. doi: 10.1186/1471-2091-13-2.

PMID:
22276637
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Systemic blockade of the hyaluronan receptor for endocytosis prevents lymph node metastasis of prostate cancer.

Simpson MA, Weigel JA, Weigel PH.

Int J Cancer. 2012 Sep 1;131(5):E836-40. doi: 10.1002/ijc.27427. Epub 2012 Feb 28.

PMID:
22234863
[PubMed - indexed for MEDLINE]
11.

Increased hyaluronan synthase-2 mRNA expression and hyaluronan accumulation with choroidal thickening: response during recovery from induced myopia.

Rada JA, Wiechmann AF, Hollaway LR, Baggenstoss BA, Weigel PH.

Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6172-9. doi: 10.1167/iovs.10-5522. Epub 2010 Jun 23.

PMID:
20574026
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

N-Glycans on the link domain of human HARE/Stabilin-2 are needed for hyaluronan binding to purified ecto-domain, but not for cellular endocytosis of hyaluronan.

Harris EN, Parry S, Sutton-Smith M, Pandey MS, Panico M, Morris HR, Haslam SM, Dell A, Weigel PH.

Glycobiology. 2010 Aug;20(8):991-1001. doi: 10.1093/glycob/cwq057. Epub 2010 Apr 14.

PMID:
20466649
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Rat and human HARE/stabilin-2 are clearance receptors for high- and low-molecular-weight heparins.

Harris EN, Baggenstoss BA, Weigel PH.

Am J Physiol Gastrointest Liver Physiol. 2009 Jun;296(6):G1191-9. doi: 10.1152/ajpgi.90717.2008. Epub 2009 Apr 9.

PMID:
19359419
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Abundance and location of proteoglycans and hyaluronan within normal and myxomatous mitral valves.

Gupta V, Barzilla JE, Mendez JS, Stephens EH, Lee EL, Collard CD, Laucirica R, Weigel PH, Grande-Allen KJ.

Cardiovasc Pathol. 2009 Jul-Aug;18(4):191-7. doi: 10.1016/j.carpath.2008.05.001. Epub 2008 Jul 14.

PMID:
18621549
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The cytoplasmic domain of the hyaluronan receptor for endocytosis (HARE) contains multiple endocytic motifs targeting coated pit-mediated internalization.

Pandey MS, Harris EN, Weigel JA, Weigel PH.

J Biol Chem. 2008 Aug 1;283(31):21453-61. doi: 10.1074/jbc.M800886200. Epub 2008 Jun 6.

PMID:
18539600
[PubMed - indexed for MEDLINE]
Free PMC Article
16.
17.

The human hyaluronan receptor for endocytosis (HARE/Stabilin-2) is a systemic clearance receptor for heparin.

Harris EN, Weigel JA, Weigel PH.

J Biol Chem. 2008 Jun 20;283(25):17341-50. doi: 10.1074/jbc.M710360200. Epub 2008 Apr 22.

PMID:
18434317
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The hyaluronan receptor for endocytosis mediates hyaluronan-dependent signal transduction via extracellular signal-regulated kinases.

Kyosseva SV, Harris EN, Weigel PH.

J Biol Chem. 2008 May 30;283(22):15047-55. doi: 10.1074/jbc.M709921200. Epub 2008 Apr 2.

PMID:
18387958
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Hyaluronan synthases: a decade-plus of novel glycosyltransferases.

Weigel PH, DeAngelis PL.

J Biol Chem. 2007 Dec 21;282(51):36777-81. Epub 2007 Nov 1. Review.

PMID:
17981795
[PubMed - indexed for MEDLINE]
Free Article
20.

An enzyme capture assay for analysis of active hyaluronan synthases.

Kyossev Z, Weigel PH.

Anal Biochem. 2007 Dec 1;371(1):62-70. Epub 2007 Aug 28.

PMID:
17904513
[PubMed - indexed for MEDLINE]

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