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Results: 1 to 20 of 43

1.

The regulator of G protein signaling (RGS) domain of G protein-coupled receptor kinase 5 (GRK5) regulates plasma membrane localization and function.

Xu H, Jiang X, Shen K, Fischer CC, Wedegaertner PB.

Mol Biol Cell. 2014 Jul 1;25(13):2105-15. doi: 10.1091/mbc.E13-09-0547. Epub 2014 May 7.

PMID:
24807909
[PubMed - in process]
2.

Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission.

Martz MK, Grabocka E, Beeharry N, Yen TJ, Wedegaertner PB.

Mol Biol Cell. 2013 Sep;24(18):2785-94. doi: 10.1091/mbc.E12-07-0533. Epub 2013 Jul 24.

PMID:
23885121
[PubMed - in process]
Free PMC Article
3.

G protein trafficking.

Wedegaertner PB.

Subcell Biochem. 2012;63:193-223. doi: 10.1007/978-94-007-4765-4_11. Review.

PMID:
23161140
[PubMed - indexed for MEDLINE]
4.

Non-canonical signaling and localizations of heterotrimeric G proteins.

Hewavitharana T, Wedegaertner PB.

Cell Signal. 2012 Jan;24(1):25-34. doi: 10.1016/j.cellsig.2011.08.014. Epub 2011 Sep 1. Review.

PMID:
21907280
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Regulation of constitutive cargo transport from the trans-Golgi network to plasma membrane by Golgi-localized G protein betagamma subunits.

Irannejad R, Wedegaertner PB.

J Biol Chem. 2010 Oct 15;285(42):32393-404. doi: 10.1074/jbc.M110.154963. Epub 2010 Aug 18.

PMID:
20720014
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

An N-terminal polybasic motif of Gαq is required for signaling and influences membrane nanodomain distribution.

Crouthamel M, Abankwa D, Zhang L, DiLizio C, Manning DR, Hancock JF, Wedegaertner PB.

Mol Pharmacol. 2010 Oct;78(4):767-77. doi: 10.1124/mol.110.066340. Epub 2010 Jul 27.

PMID:
20664004
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The amino acid motif L/IIxxFE defines a novel actin-binding sequence in PDZ-RhoGEF.

Banerjee J, Fischer CC, Wedegaertner PB.

Biochemistry. 2009 Aug 25;48(33):8032-43. doi: 10.1021/bi9010013.

PMID:
19618964
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Differences in Galpha12- and Galpha13-mediated plasma membrane recruitment of p115-RhoGEF.

Bhattacharyya R, Banerjee J, Khalili K, Wedegaertner PB.

Cell Signal. 2009 Jun;21(6):996-1006. doi: 10.1016/j.cellsig.2009.02.010. Epub 2009 Feb 25.

PMID:
19249348
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

N-terminal polybasic motifs are required for plasma membrane localization of Galpha(s) and Galpha(q).

Crouthamel M, Thiyagarajan MM, Evanko DS, Wedegaertner PB.

Cell Signal. 2008 Oct;20(10):1900-10. doi: 10.1016/j.cellsig.2008.06.019. Epub 2008 Jul 2.

PMID:
18647648
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts.

Iwanicki MP, Vomastek T, Tilghman RW, Martin KH, Banerjee J, Wedegaertner PB, Parsons JT.

J Cell Sci. 2008 Mar 15;121(Pt 6):895-905. doi: 10.1242/jcs.020941. Epub 2008 Feb 26.

PMID:
18303050
[PubMed - indexed for MEDLINE]
Free Article
11.

Disruption of oligomerization induces nucleocytoplasmic shuttling of leukemia-associated rho Guanine-nucleotide exchange factor.

Grabocka E, Wedegaertner PB.

Mol Pharmacol. 2007 Oct;72(4):993-1002. Epub 2007 Jul 3.

PMID:
17609419
[PubMed - indexed for MEDLINE]
Free Article
12.

Assembly and trafficking of heterotrimeric G proteins.

Marrari Y, Crouthamel M, Irannejad R, Wedegaertner PB.

Biochemistry. 2007 Jul 3;46(26):7665-77. Epub 2007 Jun 9. Review.

PMID:
17559193
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Plasma membrane and nuclear localization of G protein coupled receptor kinase 6A.

Jiang X, Benovic JL, Wedegaertner PB.

Mol Biol Cell. 2007 Aug;18(8):2960-9. Epub 2007 May 30.

PMID:
17538017
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Lipid-protein interactions in GPCR-associated signaling.

Escribá PV, Wedegaertner PB, Goñi FM, Vögler O.

Biochim Biophys Acta. 2007 Apr;1768(4):836-52. Epub 2006 Sep 16. Review.

PMID:
17067547
[PubMed - indexed for MEDLINE]
Free Article
15.

Cooperative regulation of p70S6 kinase by receptor tyrosine kinases and G protein-coupled receptors augments airway smooth muscle growth.

Billington CK, Kong KC, Bhattacharyya R, Wedegaertner PB, Panettieri RA Jr, Chan TO, Penn RB.

Biochemistry. 2005 Nov 8;44(44):14595-605.

PMID:
16262259
[PubMed - indexed for MEDLINE]
16.

Loss of association between activated Galpha q and Gbetagamma disrupts receptor-dependent and receptor-independent signaling.

Evanko DS, Thiyagarajan MM, Takida S, Wedegaertner PB.

Cell Signal. 2005 Oct;17(10):1218-28. Epub 2005 Jan 22.

PMID:
16038796
[PubMed - indexed for MEDLINE]
17.

Functional consequences of G alpha 13 mutations that disrupt interaction with p115RhoGEF.

Grabocka E, Wedegaertner PB.

Oncogene. 2005 Mar 24;24(13):2155-65.

PMID:
15735747
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Palmitoylation and plasma membrane targeting of RGS7 are promoted by alpha o.

Takida S, Fischer CC, Wedegaertner PB.

Mol Pharmacol. 2005 Jan;67(1):132-9. Epub 2004 Oct 20.

PMID:
15496508
[PubMed - indexed for MEDLINE]
Free Article
19.

Analysis of G-protein-coupled receptor kinase RGS homology domains.

Day PW, Wedegaertner PB, Benovic JL.

Methods Enzymol. 2004;390:295-310.

PMID:
15488185
[PubMed - indexed for MEDLINE]
20.

Characterization of the GRK2 binding site of Galphaq.

Day PW, Tesmer JJ, Sterne-Marr R, Freeman LC, Benovic JL, Wedegaertner PB.

J Biol Chem. 2004 Dec 17;279(51):53643-52. Epub 2004 Oct 7.

PMID:
15471870
[PubMed - indexed for MEDLINE]
Free PMC Article

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