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Results: 1 to 20 of 52

1.

Evidence-Based Policy and Practice Leads to Changes in the Criteria for MSM to Donate Blood.

Slowther A, Watkins NA, Kelly D.

Transfus Med Hemother. 2013 Jun;40(3):155-8. doi: 10.1159/000351770. Epub 2013 May 17.

PMID:
23922540
[PubMed]
Free PMC Article
2.

SMIM1 underlies the Vel blood group and influences red blood cell traits.

Cvejic A, Haer-Wigman L, Stephens JC, Kostadima M, Smethurst PA, Frontini M, van den Akker E, Bertone P, Bielczyk-Maczyńska E, Farrow S, Fehrmann RS, Gray A, de Haas M, Haver VG, Jordan G, Karjalainen J, Kerstens HH, Kiddle G, Lloyd-Jones H, Needs M, Poole J, Soussan AA, Rendon A, Rieneck K, Sambrook JG, Schepers H, Silljé HH, Sipos B, Swinkels D, Tamuri AU, Verweij N, Watkins NA, Westra HJ, Stemple D, Franke L, Soranzo N, Stunnenberg HG, Goldman N, van der Harst P, van der Schoot CE, Ouwehand WH, Albers CA.

Nat Genet. 2013 May;45(5):542-5. doi: 10.1038/ng.2603. Epub 2013 Apr 7.

PMID:
23563608
[PubMed - indexed for MEDLINE]
3.

Canonical Wnt signaling in megakaryocytes regulates proplatelet formation.

Macaulay IC, Thon JN, Tijssen MR, Steele BM, MacDonald BT, Meade G, Burns P, Rendon A, Salunkhe V, Murphy RP, Bennett C, Watkins NA, He X, Fitzgerald DJ, Italiano JE Jr, Maguire PB.

Blood. 2013 Jan 3;121(1):188-96. doi: 10.1182/blood-2012-03-416875. Epub 2012 Nov 16.

PMID:
23160460
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Monocyte gene expression signature of patients with early onset coronary artery disease.

Sivapalaratnam S, Basart H, Watkins NA, Maiwald S, Rendon A, Krishnan U, Sondermeijer BM, Creemers EE, Pinto-Sietsma SJ, Hovingh K, Ouwehand WH, Kastelein JJ, Goodall AH, Trip MD.

PLoS One. 2012;7(2):e32166. doi: 10.1371/journal.pone.0032166. Epub 2012 Feb 21.

PMID:
22363809
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Inhibition of MT1-MMP activity using functional antibody fragments selected against its hemopexin domain.

Basu B, Correa de Sampaio P, Mohammed H, Fogarasi M, Corrie P, Watkins NA, Smethurst PA, English WR, Ouwehand WH, Murphy G.

Int J Biochem Cell Biol. 2012 Feb;44(2):393-403. doi: 10.1016/j.biocel.2011.11.015. Epub 2011 Nov 26.

PMID:
22138224
[PubMed - indexed for MEDLINE]
6.

The management of blood safety in the presence of uncertain risk: a United kingdom perspective.

Watkins NA, Dobra S, Bennett P, Cairns J, Turner ML.

Transfus Med Rev. 2012 Jul;26(3):238-51. doi: 10.1016/j.tmrv.2011.09.003. Epub 2011 Nov 29. Review.

PMID:
22126710
[PubMed - indexed for MEDLINE]
7.

SaBTO review of blood donor selection criteria related to sexual behaviour.

Watkins NA, Brailsford S, Kelly D.

Transfus Med. 2011 Dec;21(6):363-4. doi: 10.1111/j.1365-3148.2011.01115.x. No abstract available.

PMID:
22082177
[PubMed - indexed for MEDLINE]
8.

Identification of candidate genes linking systemic inflammation to atherosclerosis; results of a human in vivo LPS infusion study.

Sivapalaratnam S, Farrugia R, Nieuwdorp M, Langford CF, van Beem RT, Maiwald S, Zwaginga JJ, Gusnanto A, Watkins NA, Trip MD, Ouwehand WH.

BMC Med Genomics. 2011 Aug 10;4:64. doi: 10.1186/1755-8794-4-64.

PMID:
21827714
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function.

Goodall AH, Burns P, Salles I, Macaulay IC, Jones CI, Ardissino D, de Bono B, Bray SL, Deckmyn H, Dudbridge F, Fitzgerald DJ, Garner SF, Gusnanto A, Koch K, Langford C, O'Connor MN, Rice CM, Stemple D, Stephens J, Trip MD, Zwaginga JJ, Samani NJ, Watkins NA, Maguire PB, Ouwehand WH; Bloodomics Consortium.

Blood. 2010 Nov 25;116(22):4646-56. doi: 10.1182/blood-2010-04-280925. Epub 2010 Sep 10.

PMID:
20833976
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Complex exon-intron marking by histone modifications is not determined solely by nucleosome distribution.

Dhami P, Saffrey P, Bruce AW, Dillon SC, Chiang K, Bonhoure N, Koch CM, Bye J, James K, Foad NS, Ellis P, Watkins NA, Ouwehand WH, Langford C, Andrews RM, Dunham I, Vetrie D.

PLoS One. 2010 Aug 23;5(8):e12339. doi: 10.1371/journal.pone.0012339.

PMID:
20808788
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.

Wellcome Trust Case Control Consortium, Craddock N, Hurles ME, Cardin N, Pearson RD, Plagnol V, Robson S, Vukcevic D, Barnes C, Conrad DF, Giannoulatou E, Holmes C, Marchini JL, Stirrups K, Tobin MD, Wain LV, Yau C, Aerts J, Ahmad T, Andrews TD, Arbury H, Attwood A, Auton A, Ball SG, Balmforth AJ, Barrett JC, Barroso I, Barton A, Bennett AJ, Bhaskar S, Blaszczyk K, Bowes J, Brand OJ, Braund PS, Bredin F, Breen G, Brown MJ, Bruce IN, Bull J, Burren OS, Burton J, Byrnes J, Caesar S, Clee CM, Coffey AJ, Connell JM, Cooper JD, Dominiczak AF, Downes K, Drummond HE, Dudakia D, Dunham A, Ebbs B, Eccles D, Edkins S, Edwards C, Elliot A, Emery P, Evans DM, Evans G, Eyre S, Farmer A, Ferrier IN, Feuk L, Fitzgerald T, Flynn E, Forbes A, Forty L, Franklyn JA, Freathy RM, Gibbs P, Gilbert P, Gokumen O, Gordon-Smith K, Gray E, Green E, Groves CJ, Grozeva D, Gwilliam R, Hall A, Hammond N, Hardy M, Harrison P, Hassanali N, Hebaishi H, Hines S, Hinks A, Hitman GA, Hocking L, Howard E, Howard P, Howson JM, Hughes D, Hunt S, Isaacs JD, Jain M, Jewell DP, Johnson T, Jolley JD, Jones IR, Jones LA, Kirov G, Langford CF, Lango-Allen H, Lathrop GM, Lee J, Lee KL, Lees C, Lewis K, Lindgren CM, Maisuria-Armer M, Maller J, Mansfield J, Martin P, Massey DC, McArdle WL, McGuffin P, McLay KE, Mentzer A, Mimmack ML, Morgan AE, Morris AP, Mowat C, Myers S, Newman W, Nimmo ER, O'Donovan MC, Onipinla A, Onyiah I, Ovington NR, Owen MJ, Palin K, Parnell K, Pernet D, Perry JR, Phillips A, Pinto D, Prescott NJ, Prokopenko I, Quail MA, Rafelt S, Rayner NW, Redon R, Reid DM, Renwick, Ring SM, Robertson N, Russell E, St Clair D, Sambrook JG, Sanderson JD, Schuilenburg H, Scott CE, Scott R, Seal S, Shaw-Hawkins S, Shields BM, Simmonds MJ, Smyth DJ, Somaskantharajah E, Spanova K, Steer S, Stephens J, Stevens HE, Stone MA, Su Z, Symmons DP, Thompson JR, Thomson W, Travers ME, Turnbull C, Valsesia A, Walker M, Walker NM, Wallace C, Warren-Perry M, Watkins NA, Webster J, Weedon MN, Wilson AG, Woodburn M, Wordsworth BP, Young AH, Zeggini E, Carter NP, Frayling TM, Lee C, McVean G, Munroe PB, Palotie A, Sawcer SJ, Scherer SW, Strachan DP, Tyler-Smith C, Brown MA, Burton PR, Caulfield MJ, Compston A, Farrall M, Gough SC, Hall AS, Hattersley AT, Hill AV, Mathew CG, Pembrey M, Satsangi J, Stratton MR, Worthington J, Deloukas P, Duncanson A, Kwiatkowski DP, McCarthy MI, Ouwehand W, Parkes M, Rahman N, Todd JA, Samani NJ, Donnelly P.

Nature. 2010 Apr 1;464(7289):713-20. doi: 10.1038/nature08979.

PMID:
20360734
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation.

Holbrook LM, Watkins NA, Simmonds AD, Jones CI, Ouwehand WH, Gibbins JM.

Br J Haematol. 2010 Feb;148(4):627-37. doi: 10.1111/j.1365-2141.2009.07994.x. Epub 2009 Dec 8.

PMID:
19995400
[PubMed - indexed for MEDLINE]
13.

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.

Soranzo N, Spector TD, Mangino M, Kühnel B, Rendon A, Teumer A, Willenborg C, Wright B, Chen L, Li M, Salo P, Voight BF, Burns P, Laskowski RA, Xue Y, Menzel S, Altshuler D, Bradley JR, Bumpstead S, Burnett MS, Devaney J, Döring A, Elosua R, Epstein SE, Erber W, Falchi M, Garner SF, Ghori MJ, Goodall AH, Gwilliam R, Hakonarson HH, Hall AS, Hammond N, Hengstenberg C, Illig T, König IR, Knouff CW, McPherson R, Melander O, Mooser V, Nauck M, Nieminen MS, O'Donnell CJ, Peltonen L, Potter SC, Prokisch H, Rader DJ, Rice CM, Roberts R, Salomaa V, Sambrook J, Schreiber S, Schunkert H, Schwartz SM, Serbanovic-Canic J, Sinisalo J, Siscovick DS, Stark K, Surakka I, Stephens J, Thompson JR, Völker U, Völzke H, Watkins NA, Wells GA, Wichmann HE, Van Heel DA, Tyler-Smith C, Thein SL, Kathiresan S, Perola M, Reilly MP, Stewart AF, Erdmann J, Samani NJ, Meisinger C, Greinacher A, Deloukas P, Ouwehand WH, Gieger C.

Nat Genet. 2009 Nov;41(11):1182-90. doi: 10.1038/ng.467. Epub 2009 Oct 11.

PMID:
19820697
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Alloantibodies against low-frequency human platelet antigens do not account for a significant proportion of cases of fetomaternal alloimmune thrombocytopenia: evidence from 1054 cases.

Ghevaert C, Rankin A, Huiskes E, Porcelijn L, Javela K, Kekomaki R, Bakchoul T, Santoso S, Nutland S, Smyth DJ, Smith GA, McBride S, Watkins NA, Ouwehand WH.

Transfusion. 2009 Oct;49(10):2084-9. doi: 10.1111/j.1537-2995.2009.02246.x. Epub 2009 Jun 4.

PMID:
19500319
[PubMed - indexed for MEDLINE]
15.

A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways.

Jones CI, Bray S, Garner SF, Stephens J, de Bono B, Angenent WG, Bentley D, Burns P, Coffey A, Deloukas P, Earthrowl M, Farndale RW, Hoylaerts MF, Koch K, Rankin A, Rice CM, Rogers J, Samani NJ, Steward M, Walker A, Watkins NA, Akkerman JW, Dudbridge F, Goodall AH, Ouwehand WH; Bloodomics Consortium.

Blood. 2009 Aug 13;114(7):1405-16. doi: 10.1182/blood-2009-02-202614. Epub 2009 May 8.

PMID:
19429868
[PubMed - indexed for MEDLINE]
Free Article
16.

A HaemAtlas: characterizing gene expression in differentiated human blood cells.

Watkins NA, Gusnanto A, de Bono B, De S, Miranda-Saavedra D, Hardie DL, Angenent WG, Attwood AP, Ellis PD, Erber W, Foad NS, Garner SF, Isacke CM, Jolley J, Koch K, Macaulay IC, Morley SL, Rendon A, Rice KM, Taylor N, Thijssen-Timmer DC, Tijssen MR, van der Schoot CE, Wernisch L, Winzer T, Dudbridge F, Buckley CD, Langford CF, Teichmann S, Göttgens B, Ouwehand WH; Bloodomics Consortium.

Blood. 2009 May 7;113(19):e1-9. doi: 10.1182/blood-2008-06-162958. Epub 2009 Feb 19.

PMID:
19228925
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function.

Soranzo N, Rendon A, Gieger C, Jones CI, Watkins NA, Menzel S, Döring A, Stephens J, Prokisch H, Erber W, Potter SC, Bray SL, Burns P, Jolley J, Falchi M, Kühnel B, Erdmann J, Schunkert H, Samani NJ, Illig T, Garner SF, Rankin A, Meisinger C, Bradley JR, Thein SL, Goodall AH, Spector TD, Deloukas P, Ouwehand WH.

Blood. 2009 Apr 16;113(16):3831-7. doi: 10.1182/blood-2008-10-184234. Epub 2009 Feb 12.

PMID:
19221038
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A genome-wide association study identifies three loci associated with mean platelet volume.

Meisinger C, Prokisch H, Gieger C, Soranzo N, Mehta D, Rosskopf D, Lichtner P, Klopp N, Stephens J, Watkins NA, Deloukas P, Greinacher A, Koenig W, Nauck M, Rimmbach C, Völzke H, Peters A, Illig T, Ouwehand WH, Meitinger T, Wichmann HE, Döring A.

Am J Hum Genet. 2009 Jan;84(1):66-71. doi: 10.1016/j.ajhg.2008.11.015. Epub 2008 Dec 24.

PMID:
19110211
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins.

O'Connor MN, Salles II, Cvejic A, Watkins NA, Walker A, Garner SF, Jones CI, Macaulay IC, Steward M, Zwaginga JJ, Bray SL, Dudbridge F, de Bono B, Goodall AH, Deckmyn H, Stemple DL, Ouwehand WH; Bloodomics Consortium.

Blood. 2009 May 7;113(19):4754-62. doi: 10.1182/blood-2008-06-162693. Epub 2008 Dec 24.

PMID:
19109564
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains.

Protty MB, Watkins NA, Colombo D, Thomas SG, Heath VL, Herbert JM, Bicknell R, Senis YA, Ashman LK, Berditchevski F, Ouwehand WH, Watson SP, Tomlinson MG.

Biochem J. 2009 Jan 1;417(1):391-400. doi: 10.1042/BJ20081126.

PMID:
18795891
[PubMed - indexed for MEDLINE]
Free PMC Article

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