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Items: 1 to 20 of 95


Progressive irreversible hearing loss is caused by stria vascularis degeneration in an Slc26a4-insufficient mouse model of large vestibular aqueduct syndrome.

Ito T, Nishio A, Wangemann P, Griffith AJ.

Neuroscience. 2015 Dec 3;310:188-97. doi: 10.1016/j.neuroscience.2015.09.016. Epub 2015 Sep 9.


Chemical synthesis of tetracyclic terpenes and evaluation of antagonistic activity on endothelin-A receptors and voltage-gated calcium channels.

Lu J, Aguilar A, Zou B, Bao W, Koldas S, Shi A, Desper J, Wangemann P, Xie XS, Hua DH.

Bioorg Med Chem. 2015 Sep 1;23(17):5985-98. doi: 10.1016/j.bmc.2015.06.055. Epub 2015 Jun 27.


ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells.

Morozko EL, Nishio A, Ingham NJ, Chandra R, Fitzgerald T, Martelletti E, Borck G, Wilson E, Riordan GP, Wangemann P, Forge A, Steel KP, Liddle RA, Friedman TB, Belyantseva IA.

Hum Mol Genet. 2015 Feb 1;24(3):609-24. doi: 10.1093/hmg/ddu474. Epub 2014 Sep 12.


Slc26a7 chloride channel activity and localization in mouse Reissner's membrane epithelium.

Kim KX, Sanneman JD, Kim HM, Harbidge DG, Xu J, Soleimani M, Wangemann P, Marcus DC.

PLoS One. 2014 May 8;9(5):e97191. doi: 10.1371/journal.pone.0097191. eCollection 2014.


Slc26a4-insufficiency causes fluctuating hearing loss and stria vascularis dysfunction.

Ito T, Li X, Kurima K, Choi BY, Wangemann P, Griffith AJ.

Neurobiol Dis. 2014 Jun;66:53-65. doi: 10.1016/j.nbd.2014.02.002. Epub 2014 Feb 19.


Mouse models for pendrin-associated loss of cochlear and vestibular function.

Wangemann P.

Cell Physiol Biochem. 2013;32(7):157-65. doi: 10.1159/000356635. Epub 2013 Dec 18. Review.


SLC26A4 targeted to the endolymphatic sac rescues hearing and balance in Slc26a4 mutant mice.

Li X, Sanneman JD, Harbidge DG, Zhou F, Ito T, Nelson R, Picard N, Chambrey R, Eladari D, Miesner T, Griffith AJ, Marcus DC, Wangemann P.

PLoS Genet. 2013;9(7):e1003641. doi: 10.1371/journal.pgen.1003641. Epub 2013 Jul 11.


Endolymphatic Na⁺ and K⁺ concentrations during cochlear growth and enlargement in mice lacking Slc26a4/pendrin.

Li X, Zhou F, Marcus DC, Wangemann P.

PLoS One. 2013 May 31;8(5):e65977. doi: 10.1371/journal.pone.0065977. Print 2013.


SLC26A4 mutation testing for hearing loss associated with enlargement of the vestibular aqueduct.

Ito T, Muskett J, Chattaraj P, Choi BY, Lee KY, Zalewski CK, King KA, Li X, Wangemann P, Shawker T, Brewer CC, Alper SL, Griffith AJ.

World J Otorhinolaryngol. 2013 May 28;3(2):26-34.


NOS inhibition enhances myogenic tone by increasing rho-kinase mediated Ca2+ sensitivity in the male but not the female gerbil spiral modiolar artery.

Reimann K, Krishnamoorthy G, Wangemann P.

PLoS One. 2013;8(1):e53655. doi: 10.1371/journal.pone.0053655. Epub 2013 Jan 3.


Developmental expression of solute carrier family 26A member 4 (SLC26A4/pendrin) during amelogenesis in developing rodent teeth.

Bronckers AL, Guo J, Zandieh-Doulabi B, Bervoets TJ, Lyaruu DM, Li X, Wangemann P, DenBesten P.

Eur J Oral Sci. 2011 Dec;119 Suppl 1:185-92. doi: 10.1111/j.1600-0722.2011.00901.x. Erratum in: Eur J Oral Sci. 2012 Apr;120(2):178.


SLC26A4 genotypes and phenotypes associated with enlargement of the vestibular aqueduct.

Ito T, Choi BY, King KA, Zalewski CK, Muskett J, Chattaraj P, Shawker T, Reynolds JC, Butman JA, Brewer CC, Wangemann P, Alper SL, Griffith AJ.

Cell Physiol Biochem. 2011;28(3):545-52. doi: 10.1159/000335119. Epub 2011 Nov 18. Review.


The role of pendrin in the development of the murine inner ear.

Wangemann P.

Cell Physiol Biochem. 2011;28(3):527-34. doi: 10.1159/000335113. Epub 2011 Nov 18. Review.


Molecular and pharmacological characteristics of the gerbil α(1a)-adrenergic receptor.

Witt KM, Bockman CS, Dang HK, Gruber DD, Wangemann P, Scofield MA.

Hear Res. 2012 Jan;283(1-2):144-50. doi: 10.1016/j.heares.2011.11.002. Epub 2011 Nov 10.


Gender differences in myogenic regulation along the vascular tree of the gerbil cochlea.

Reimann K, Krishnamoorthy G, Wier WG, Wangemann P.

PLoS One. 2011;6(9):e25659. doi: 10.1371/journal.pone.0025659. Epub 2011 Sep 29.


Mouse model of enlarged vestibular aqueducts defines temporal requirement of Slc26a4 expression for hearing acquisition.

Choi BY, Kim HM, Ito T, Lee KY, Li X, Monahan K, Wen Y, Wilson E, Kurima K, Saunders TL, Petralia RS, Wangemann P, Friedman TB, Griffith AJ.

J Clin Invest. 2011 Nov;121(11):4516-25. doi: 10.1172/JCI59353. Epub 2011 Oct 3.


Calcium sparks in the intact gerbil spiral modiolar artery.

Krishnamoorthy G, Regehr K, Berge S, Scherer EQ, Wangemann P.

BMC Physiol. 2011 Aug 26;11:15. doi: 10.1186/1472-6793-11-15.


Hearing loss associated with enlargement of the vestibular aqueduct: mechanistic insights from clinical phenotypes, genotypes, and mouse models.

Griffith AJ, Wangemann P.

Hear Res. 2011 Nov;281(1-2):11-7. doi: 10.1016/j.heares.2011.05.009. Epub 2011 Jun 6. Review.

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