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Items: 1 to 20 of 46


A High Affinity hRpn2-Derived Peptide That Displaces Human Rpn13 from Proteasome in 293T Cells.

Lu X, Liu F, Durham SE, Tarasov SG, Walters KJ.

PLoS One. 2015 Oct 14;10(10):e0140518. doi: 10.1371/journal.pone.0140518. eCollection 2015.


Artificial targeting of misfolded cytosolic proteins to endoplasmic reticulum as a mechanism for clearance.

Liu F, Koepp DM, Walters KJ.

Sci Rep. 2015 Jul 14;5:12088. doi: 10.1038/srep12088.


Structural plasticity allows UCH37 to be primed by RPN13 or locked down by INO80G.

Chen X, Walters KJ.

Mol Cell. 2015 Mar 5;57(5):767-8. doi: 10.1016/j.molcel.2015.02.025.


A bis-benzylidine piperidone targeting proteasome ubiquitin receptor RPN13/ADRM1 as a therapy for cancer.

Anchoori RK, Karanam B, Peng S, Wang JW, Jiang R, Tanno T, Orlowski RZ, Matsui W, Zhao M, Rudek MA, Hung CF, Chen X, Walters KJ, Roden RB.

Cancer Cell. 2013 Dec 9;24(6):791-805. doi: 10.1016/j.ccr.2013.11.001.


Structural insights into proteasome activation by the 19S regulatory particle.

Ehlinger A, Walters KJ.

Biochemistry. 2013 May 28;52(21):3618-28. doi: 10.1021/bi400417a. Epub 2013 May 14.


Conformational dynamics of the Rpt6 ATPase in proteasome assembly and Rpn14 binding.

Ehlinger A, Park S, Fahmy A, Lary JW, Cole JL, Finley D, Walters KJ.

Structure. 2013 May 7;21(5):753-65. doi: 10.1016/j.str.2013.02.021. Epub 2013 Apr 4.


MTMDAT-HADDOCK: high-throughput, protein complex structure modeling based on limited proteolysis and mass spectrometry.

Hennig J, de Vries SJ, Hennig KD, Randles L, Walters KJ, Sunnerhagen M, Bonvin AM.

BMC Struct Biol. 2012 Nov 15;12:29. doi: 10.1186/1472-6807-12-29.


In support of the BMRB.

Markley JL, Akutsu H, Asakura T, Baldus M, Boelens R, Bonvin A, Kaptein R, Bax A, Bezsonova I, Gryk MR, Hoch JC, Korzhnev DM, Maciejewski MW, Case D, Chazin WJ, Cross TA, Dames S, Kessler H, Lange O, Madl T, Reif B, Sattler M, Eliezer D, Fersht A, Forman-Kay J, Kay LE, Fraser J, Gross J, Kortemme T, Sali A, Fujiwara T, Gardner K, Luo X, Rizo-Rey J, Rosen M, Gil RR, Ho C, Rule G, Gronenborn AM, Ishima R, Klein-Seetharaman J, Tang P, van der Wel P, Xu Y, Grzesiek S, Hiller S, Seelig J, Laue ED, Mott H, Nietlispach D, Barsukov I, Lian LY, Middleton D, Blumenschein T, Moore G, Campbell I, Schnell J, Vakonakis IJ, Watts A, Conte MR, Mason J, Pfuhl M, Sanderson MR, Craven J, Williamson M, Dominguez C, Roberts G, Günther U, Overduin M, Werner J, Williamson P, Blindauer C, Crump M, Driscoll P, Frenkiel T, Golovanov A, Matthews S, Parkinson J, Uhrin D, Williams M, Neuhaus D, Oschkinat H, Ramos A, Shaw DE, Steinbeck C, Vendruscolo M, Vuister GW, Walters KJ, Weinstein H, Wüthrich K, Yokoyama S.

Nat Struct Mol Biol. 2012 Sep;19(9):854-60. doi: 10.1038/nsmb.2371. No abstract available.


Ubiquitin and its binding domains.

Randles L, Walters KJ.

Front Biosci (Landmark Ed). 2012 Jun 1;17:2140-57. Review.


Identifying and studying ubiquitin receptors by NMR.

Chen X, Walters KJ.

Methods Mol Biol. 2012;832:279-303. doi: 10.1007/978-1-61779-474-2_20.


Policing Parkin with a UblD.

Liu F, Walters KJ.

EMBO J. 2011 Jul 20;30(14):2757-8. doi: 10.1038/emboj.2011.223. No abstract available.


Structure of proteasome ubiquitin receptor hRpn13 and its activation by the scaffolding protein hRpn2.

Chen X, Lee BH, Finley D, Walters KJ.

Mol Cell. 2010 May 14;38(3):404-15. doi: 10.1016/j.molcel.2010.04.019.


Multitasking with ubiquitin through multivalent interactions.

Liu F, Walters KJ.

Trends Biochem Sci. 2010 Jun;35(6):352-60. doi: 10.1016/j.tibs.2010.01.002. Epub 2010 Feb 22. Review.


Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190.

Zhou X, Zhang N, Liu L, Walters KJ, Hanna PE, Wagner CR.

FEBS J. 2009 Dec;276(23):6928-41. doi: 10.1111/j.1742-4658.2009.07389.x. Epub 2009 Oct 23.


Ubiquitin-binding domains - from structures to functions.

Dikic I, Wakatsuki S, Walters KJ.

Nat Rev Mol Cell Biol. 2009 Oct;10(10):659-71. doi: 10.1038/nrm2767. Review.


Measuring ubiquitin chain linkage: Rap80 uses a molecular ruler mechanism for ubiquitin linkage specificity.

Walters KJ, Chen X.

EMBO J. 2009 Aug 19;28(16):2307-8. doi: 10.1038/emboj.2009.221. No abstract available.


Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13.

Zhang N, Wang Q, Ehlinger A, Randles L, Lary JW, Kang Y, Haririnia A, Storaska AJ, Cole JL, Fushman D, Walters KJ.

Mol Cell. 2009 Aug 14;35(3):280-90. doi: 10.1016/j.molcel.2009.06.010.


Prokaryotic ubiquitin-like protein pup is intrinsically disordered.

Chen X, Solomon WC, Kang Y, Cerda-Maira F, Darwin KH, Walters KJ.

J Mol Biol. 2009 Sep 11;392(1):208-17. doi: 10.1016/j.jmb.2009.07.018. Epub 2009 Jul 14.


Insights into how protein dynamics affects arylamine N-acetyltransferase catalysis.

Zhang N, Walters KJ.

Biochem Biophys Res Commun. 2009 Jul 31;385(3):395-401. doi: 10.1016/j.bbrc.2009.05.065. Epub 2009 May 20.


Rpn10 protects the proteasome from Dsk2.

Walters KJ, Zhang N.

Mol Cell. 2008 Nov 21;32(4):459-60. doi: 10.1016/j.molcel.2008.10.020.

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