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Results: 1 to 20 of 41


Production and characterization of thirteen human type-I interferon-α subtypes.

Kuruganti S, Accavitti-Loper MA, Walter MR.

Protein Expr Purif. 2014 Nov;103:75-83. doi: 10.1016/j.pep.2014.08.010. Epub 2014 Aug 20.


The old but new IgM Fc receptor (FcμR).

Kubagawa H, Kubagawa Y, Jones D, Nasti TH, Walter MR, Honjo K.

Curr Top Microbiol Immunol. 2014;382:3-28. doi: 10.1007/978-3-319-07911-0_1. Review.


The molecular basis of IL-10 function: from receptor structure to the onset of signaling.

Walter MR.

Curr Top Microbiol Immunol. 2014;380:191-212. doi: 10.1007/978-3-662-43492-5_9. Review.


Very early onset inflammatory bowel disease associated with aberrant trafficking of IL-10R1 and cure by T cell replete haploidentical bone marrow transplantation.

Murugan D, Albert MH, Langemeier J, Bohne J, Puchalka J, Järvinen PM, Hauck F, Klenk AK, Prell C, Schatz S, Diestelhorst J, Sciskala B, Kohistani N, Belohradsky BH, Müller S, Kirchner T, Walter MR, Bufler P, Muise AM, Snapper SB, Koletzko S, Klein C, Kotlarz D.

J Clin Immunol. 2014 Apr;34(3):331-9. doi: 10.1007/s10875-014-9992-8. Epub 2014 Feb 12.


Vaccination against a virus-encoded cytokine significantly restricts viral challenge.

Eberhardt MK, Deshpande A, Chang WL, Barthold SW, Walter MR, Barry PA.

J Virol. 2013 Nov;87(21):11323-31. doi: 10.1128/JVI.01925-13. Epub 2013 Aug 14.


Kinetic analysis of cytokine-mediated receptor assembly using engineered FC heterodimers.

Deshpande A, Putcha BD, Kuruganti S, Walter MR.

Protein Sci. 2013 Aug;22(8):1100-8. doi: 10.1002/pro.2285. Epub 2013 Jun 6.


Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines.

Logsdon NJ, Deshpande A, Harris BD, Rajashankar KR, Walter MR.

Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12704-9. doi: 10.1073/pnas.1117551109. Epub 2012 Jul 16.


Epstein-Barr virus IL-10 engages IL-10R1 by a two-step mechanism leading to altered signaling properties.

Yoon SI, Jones BC, Logsdon NJ, Harris BD, Kuruganti S, Walter MR.

J Biol Chem. 2012 Aug 3;287(32):26586-95. doi: 10.1074/jbc.M112.376707. Epub 2012 Jun 12.


Host immune responses to a viral immune modulating protein: immunogenicity of viral interleukin-10 in rhesus cytomegalovirus-infected rhesus macaques.

Eberhardt MK, Chang WL, Logsdon NJ, Yue Y, Walter MR, Barry PA.

PLoS One. 2012;7(5):e37931. doi: 10.1371/journal.pone.0037931. Epub 2012 May 24.


Purification, crystallization and preliminary X-ray diffraction analysis of the IL-20-IL-20R1-IL-20R2 complex.

Logsdon NJ, Allen CE, Rajashankar KR, Walter MR.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jan 1;68(Pt 1):89-92. doi: 10.1107/S1744309111049529. Epub 2011 Dec 24.


Design and analysis of rhesus cytomegalovirus IL-10 mutants as a model for novel vaccines against human cytomegalovirus.

Logsdon NJ, Eberhardt MK, Allen CE, Barry PA, Walter MR.

PLoS One. 2011;6(11):e28127. doi: 10.1371/journal.pone.0028127. Epub 2011 Nov 21.


Interleukin-26: an IL-10-related cytokine produced by Th17 cells.

Donnelly RP, Sheikh F, Dickensheets H, Savan R, Young HA, Walter MR.

Cytokine Growth Factor Rev. 2010 Oct;21(5):393-401. doi: 10.1016/j.cytogfr.2010.09.001. Epub 2010 Oct 14. Review.


Substitution of adenovirus serotype 3 hexon onto a serotype 5 oncolytic adenovirus reduces factor X binding, decreases liver tropism, and improves antitumor efficacy.

Short JJ, Rivera AA, Wu H, Walter MR, Yamamoto M, Mathis JM, Curiel DT.

Mol Cancer Ther. 2010 Sep;9(9):2536-44. doi: 10.1158/1535-7163.MCT-10-0332. Epub 2010 Aug 24.


Cytokine-receptor interactions as drug targets.

Schreiber G, Walter MR.

Curr Opin Chem Biol. 2010 Aug;14(4):511-9. doi: 10.1016/j.cbpa.2010.06.165. Epub 2010 Jul 7. Review.


Structure and mechanism of receptor sharing by the IL-10R2 common chain.

Yoon SI, Jones BC, Logsdon NJ, Harris BD, Deshpande A, Radaeva S, Halloran BA, Gao B, Walter MR.

Structure. 2010 May 12;18(5):638-48. doi: 10.1016/j.str.2010.02.009.


A docking model based on mass spectrometric and biochemical data describes phage packaging motor incorporation.

Fu CY, Uetrecht C, Kang S, Morais MC, Heck AJ, Walter MR, Prevelige PE Jr.

Mol Cell Proteomics. 2010 Aug;9(8):1764-73. doi: 10.1074/mcp.M900625-MCP200. Epub 2010 Feb 2.


Structure of IL-22 bound to its high-affinity IL-22R1 chain.

Jones BC, Logsdon NJ, Walter MR.

Structure. 2008 Sep 10;16(9):1333-44. doi: 10.1016/j.str.2008.06.005. Epub 2008 Jul 3.


Crystallization and preliminary X-ray diffraction analysis of human IL-22 bound to the extracellular IL-22R1 chain.

Jones BC, Logsdon NJ, Walter MR.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Apr 1;64(Pt 4):266-9. doi: 10.1107/S1744309108004752. Epub 2008 Mar 21.


Structure and mechanism of IFN-gamma antagonism by an orthopoxvirus IFN-gamma-binding protein.

Nuara AA, Walter LJ, Logsdon NJ, Yoon SI, Jones BC, Schriewer JM, Buller RM, Walter MR.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1861-6. doi: 10.1073/pnas.0705753105. Epub 2008 Feb 5.


Protein crystallization.

Deivanayagam C, Cook WJ, Walter MR.

Methods Mol Biol. 2007;383:337-49. doi: 10.1007/978-1-59745-335-6_22.

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