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Items: 1 to 20 of 46

1.

NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions.

Vlantis K, Wullaert A, Polykratis A, Kondylis V, Dannappel M, Schwarzer R, Welz P, Corona T, Walczak H, Weih F, Klein U, Kelliher M, Pasparakis M.

Immunity. 2016 Mar 15;44(3):553-67. doi: 10.1016/j.immuni.2016.02.020.

2.

LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes.

Draber P, Kupka S, Reichert M, Draberova H, Lafont E, de Miguel D, Spilgies L, Surinova S, Taraborrelli L, Hartwig T, Rieser E, Martino L, Rittinger K, Walczak H.

Cell Rep. 2015 Dec 15;13(10):2258-72. doi: 10.1016/j.celrep.2015.11.009. Epub 2015 Dec 6.

3.

Linear ubiquitination in immunity.

Shimizu Y, Taraborrelli L, Walczak H.

Immunol Rev. 2015 Jul;266(1):190-207. doi: 10.1111/imr.12309.

4.

Oncogenic KRAS sensitizes premalignant, but not malignant cells, to Noxa-dependent apoptosis through the activation of the MEK/ERK pathway.

Conti A, Majorini MT, Elliott R, Ashworth A, Lord CJ, Cancelliere C, Bardelli A, Seneci P, Walczak H, Delia D, Lecis D.

Oncotarget. 2015 May 10;6(13):10994-1008.

5.

UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases.

Lewis MJ, Vyse S, Shields AM, Boeltz S, Gordon PA, Spector TD, Lehner PJ, Walczak H, Vyse TJ.

Am J Hum Genet. 2015 Feb 5;96(2):221-34. doi: 10.1016/j.ajhg.2014.12.024. Epub 2015 Jan 29.

6.

TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice.

Rickard JA, Anderton H, Etemadi N, Nachbur U, Darding M, Peltzer N, Lalaoui N, Lawlor KE, Vanyai H, Hall C, Bankovacki A, Gangoda L, Wong WW, Corbin J, Huang C, Mocarski ES, Murphy JM, Alexander WS, Voss AK, Vaux DL, Kaiser WJ, Walczak H, Silke J.

Elife. 2014 Dec 2;3. doi: 10.7554/eLife.03464.

7.

Bortezomib sensitises TRAIL-resistant HPV-positive head and neck cancer cells to TRAIL through a caspase-dependent, E6-independent mechanism.

Bullenkamp J, Raulf N, Ayaz B, Walczak H, Kulms D, Odell E, Thavaraj S, Tavassoli M.

Cell Death Dis. 2014 Oct 23;5:e1489. doi: 10.1038/cddis.2014.455.

8.

Differential response of head and neck cancer cell lines to TRAIL or Smac mimetics is associated with the cellular levels and activity of caspase-8 and caspase-10.

Raulf N, El-Attar R, Kulms D, Lecis D, Delia D, Walczak H, Papenfuss K, Odell E, Tavassoli M.

Br J Cancer. 2014 Nov 11;111(10):1955-64. doi: 10.1038/bjc.2014.521. Epub 2014 Oct 14.

9.

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Campanella M, Candi E, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, Di Daniele N, Dixit VM, Dynlacht BD, El-Deiry WS, Fimia GM, Flavell RA, Fulda S, Garrido C, Gougeon ML, Green DR, Gronemeyer H, Hajnoczky G, Hardwick JM, Hengartner MO, Ichijo H, Joseph B, Jost PJ, Kaufmann T, Kepp O, Klionsky DJ, Knight RA, Kumar S, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lugli E, Madeo F, Malorni W, Marine JC, Martin SJ, Martinou JC, Medema JP, Meier P, Melino S, Mizushima N, Moll U, Muñoz-Pinedo C, Nuñez G, Oberst A, Panaretakis T, Penninger JM, Peter ME, Piacentini M, Pinton P, Prehn JH, Puthalakath H, Rabinovich GA, Ravichandran KS, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Shi Y, Simon HU, Stockwell BR, Szabadkai G, Tait SW, Tang HL, Tavernarakis N, Tsujimoto Y, Vanden Berghe T, Vandenabeele P, Villunger A, Wagner EF, Walczak H, White E, Wood WG, Yuan J, Zakeri Z, Zhivotovsky B, Melino G, Kroemer G.

Cell Death Differ. 2015 Jan;22(1):58-73. doi: 10.1038/cdd.2014.137. Epub 2014 Sep 19. Review.

10.

Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout.

Ehlken H, Krishna-Subramanian S, Ochoa-Callejero L, Kondylis V, Nadi NE, Straub BK, Schirmacher P, Walczak H, Kollias G, Pasparakis M.

Cell Death Differ. 2014 Nov;21(11):1721-32. doi: 10.1038/cdd.2014.83. Epub 2014 Jun 27.

11.

Getting TRAIL back on track for cancer therapy.

Lemke J, von Karstedt S, Zinngrebe J, Walczak H.

Cell Death Differ. 2014 Sep;21(9):1350-64. doi: 10.1038/cdd.2014.81. Epub 2014 Jun 20. Review.

12.

TRAIL-R2-specific antibodies and recombinant TRAIL can synergise to kill cancer cells.

Tuthill MH, Montinaro A, Zinngrebe J, Prieske K, Draber P, Prieske S, Newsom-Davis T, von Karstedt S, Graves J, Walczak H.

Oncogene. 2015 Apr 16;34(16):2138-44. doi: 10.1038/onc.2014.156. Epub 2014 Jun 9.

13.

The seven wonders of ubiquitin: a multi-interview: Personal insights into the ubiquitin field. Interview by Nonia Pariente.

Dikic I, Harper W, Hay R, Langer T, Rape M, Sixma T, Walczak H.

EMBO Rep. 2014 Jan;15(1):7-11. doi: 10.1002/embr.201338230. No abstract available.

14.

Ubiquitin in the immune system.

Zinngrebe J, Montinaro A, Peltzer N, Walczak H.

EMBO Rep. 2014 Jan;15(1):28-45. doi: 10.1002/embr.201338025. Epub 2013 Dec 27. Review. Erratum in: EMBO Rep. 2014 Mar;15(3):322.

15.

Selective CDK9 inhibition overcomes TRAIL resistance by concomitant suppression of cFlip and Mcl-1.

Lemke J, von Karstedt S, Abd El Hay M, Conti A, Arce F, Montinaro A, Papenfuss K, El-Bahrawy MA, Walczak H.

Cell Death Differ. 2014 Mar;21(3):491-502. doi: 10.1038/cdd.2013.179. Epub 2013 Dec 20.

16.

Smac mimetics induce inflammation and necrotic tumour cell death by modulating macrophage activity.

Lecis D, De Cesare M, Perego P, Conti A, Corna E, Drago C, Seneci P, Walczak H, Colombo MP, Delia D, Sangaletti S.

Cell Death Dis. 2013 Nov 14;4:e920. doi: 10.1038/cddis.2013.449.

17.

Cytosolic and nuclear caspase-8 have opposite impact on survival after liver resection for hepatocellular carcinoma.

Koschny R, Brost S, Hinz U, Sykora J, Batke EM, Singer S, Breuhahn K, Stremmel W, Walczak H, Schemmer P, Schirmacher P, Ganten TM.

BMC Cancer. 2013 Nov 9;13:532. doi: 10.1186/1471-2407-13-532.

18.

Development of a human three-dimensional organotypic skin-melanoma spheroid model for in vitro drug testing.

Vörsmann H, Groeber F, Walles H, Busch S, Beissert S, Walczak H, Kulms D.

Cell Death Dis. 2013 Jul 11;4:e719. doi: 10.1038/cddis.2013.249.

19.

Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury.

Linkermann A, Bräsen JH, Darding M, Jin MK, Sanz AB, Heller JO, De Zen F, Weinlich R, Ortiz A, Walczak H, Weinberg JM, Green DR, Kunzendorf U, Krautwald S.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12024-9. doi: 10.1073/pnas.1305538110. Epub 2013 Jul 1.

20.

Death receptor-ligand systems in cancer, cell death, and inflammation.

Walczak H.

Cold Spring Harb Perspect Biol. 2013 May 1;5(5):a008698. doi: 10.1101/cshperspect.a008698. Review.

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