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Results: 1 to 20 of 600

1.

The addition of R262K to the H51Y mutation in HIV-1 subtype B integrase confers low-level resistance against dolutegravir.

Cutillas V, Mesplede T, Anstett K, Hassounah S, Wainberg MA.

Antimicrob Agents Chemother. 2014 Oct 27. pii: AAC.04274-14. [Epub ahead of print]

PMID:
25348535
[PubMed - as supplied by publisher]
2.

Trichiconins A-C, Limonoids with New Carbon Skeletons from Trichilia connaroides.

Liu CP, Xu JB, Han YS, Wainberg MA, Yue JM.

Org Lett. 2014 Oct 17;16(20):5478-81. doi: 10.1021/ol5027552. Epub 2014 Oct 8.

PMID:
25296007
[PubMed - in process]
3.

A Significant Reduction in the Frequency of HIV-1 Drug Resistance in Québec from 2001 to 2011 Is Associated with a Decrease in the Monitored Viral Load.

Charest H, Doualla-Bell F, Cantin R, Murphy DG, Lemieux L, Brenner B, Hardy I, Moisi D, Lo E, Baril JG, Wainberg MA, Roger M, Tremblay C.

PLoS One. 2014 Oct 8;9(10):e109420. doi: 10.1371/journal.pone.0109420. eCollection 2014.

PMID:
25295725
[PubMed - in process]
Free PMC Article
4.

Identification of an env-defective HIV-1 mutant capable of spontaneous reversion to a wild-type phenotype in certain T-cell lines.

Quan Y, Xu H, Kramer VG, Han Y, Sloan RD, Wainberg MA.

Virol J. 2014 Oct 6;11:177. doi: 10.1186/1743-422X-11-177.

PMID:
25287969
[PubMed - in process]
Free Article
5.

Evolution of a novel pathway leading to dolutegravir resistance in a patient harbouring N155H and multiclass drug resistance.

Hardy I, Brenner B, Quashie P, Thomas R, Petropoulos C, Huang W, Moisi D, Wainberg MA, Roger M.

J Antimicrob Chemother. 2014 Oct 3. pii: dku387. [Epub ahead of print]

PMID:
25281399
[PubMed - as supplied by publisher]
6.

Eurifoloids A-R, Structurally Diverse Diterpenoids from Euphorbia neriifolia.

Zhao JX, Liu CP, Qi WY, Han ML, Han YS, Wainberg MA, Yue JM.

J Nat Prod. 2014 Oct 24;77(10):2224-33. doi: 10.1021/np5004752. Epub 2014 Sep 25.

PMID:
25252924
[PubMed - in process]
7.

Fitness impaired drug resistant HIV-1 is not compromised in cell-to-cell transmission or establishment of and reactivation from latency.

Bastarache SM, Mesplède T, Donahue DA, Sloan RD, Wainberg MA.

Viruses. 2014 Sep 19;6(9):3487-99. doi: 10.3390/v6093487.

PMID:
25243372
[PubMed - in process]
Free PMC Article
8.

HIV-1 Group O Integrase Displays Lower Enzymatic Efficiency and Higher Susceptibility to Raltegravir than HIV-1 Group M Subtype B Integrase.

Depatureaux A, Quashie PK, Mesplède T, Han Y, Koubi H, Plantier JC, Oliveira M, Moisi D, Brenner B, Wainberg MA.

Antimicrob Agents Chemother. 2014 Dec;58(12):7141-50. doi: 10.1128/AAC.03819-14. Epub 2014 Sep 15.

PMID:
25224008
[PubMed - in process]
9.

Early immune adaptation in HIV-1 revealed by population-level approaches.

Martin E, Carlson JM, Le AQ, Chopera DR, McGovern R, Rahman MA, Ng C, Jessen H, Kelleher AD, Markowitz M, Allen TM, Milloy MJ, Carrington M, Wainberg MA, Brumme ZL.

Retrovirology. 2014 Aug 29;11(1):64. [Epub ahead of print]

PMID:
25212686
[PubMed - as supplied by publisher]
Free PMC Article
10.

Is resistance to dolutegravir possible when this drug is used in first-line therapy?

Mesplède T, Wainberg MA.

Viruses. 2014 Aug 27;6(9):3377-85. doi: 10.3390/v6093377.

PMID:
25166745
[PubMed - in process]
Free PMC Article
11.

Integrase Strand Transfer Inhibitors in HIV Therapy.

Mesplède T, Wainberg MA.

Infect Dis Ther. 2013 Dec;2(2):83-93. doi: 10.1007/s40121-013-0020-8. Epub 2013 Nov 19.

PMID:
25134473
[PubMed]
Free PMC Article
12.

The 20th International AIDS Conference: where do we go from here?

Wainberg MA, Kippax S, Bras M, Salif Sow P.

J Int AIDS Soc. 2014 Jul 18;17:19331. doi: 10.7448/IAS.17.1.19331. eCollection 2014. No abstract available.

PMID:
25043381
[PubMed - in process]
Free PMC Article
13.

Do HIV-1 non-B subtypes differentially impact resistance mutations and clinical disease progression in treated populations? Evidence from a systematic review.

Bhargava M, Cajas JM, Wainberg MA, Klein MB, Pant Pai N.

J Int AIDS Soc. 2014 Jul 4;17:18944. doi: 10.7448/IAS.17.1.18944. eCollection 2014. Review.

PMID:
24998532
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Effect of HIV-1 integrase resistance mutations when introduced into SIVmac239 on susceptibility to integrase strand transfer inhibitors.

Hassounah SA, Mesplède T, Quashie PK, Oliveira M, Sandstrom PA, Wainberg MA.

J Virol. 2014 Sep 1;88(17):9683-92. doi: 10.1128/JVI.00947-14. Epub 2014 Jun 11.

PMID:
24920794
[PubMed - in process]
15.

Addition of E138K to R263K in HIV integrase increases resistance to dolutegravir, but fails to restore activity of the HIV integrase enzyme and viral replication capacity.

Mesplède T, Osman N, Wares M, Quashie PK, Hassounah S, Anstett K, Han Y, Singhroy DN, Wainberg MA.

J Antimicrob Chemother. 2014 Oct;69(10):2733-40. doi: 10.1093/jac/dku199. Epub 2014 Jun 10.

PMID:
24917583
[PubMed - in process]
16.

Exposure to entry inhibitors alters HIV infectiousness and sensitivity to broadly neutralizing monoclonal antibodies.

Kramer VG, Varsaneux O, Oliviera M, Colby-Germinario SP, Mesplède T, Wainberg MA.

J Acquir Immune Defic Syndr. 2014 Sep 1;67(1):7-14. doi: 10.1097/QAI.0000000000000223.

PMID:
24872133
[PubMed - in process]
17.

Effects of the W153L substitution in HIV reverse transcriptase on viral replication and drug resistance to multiple categories of reverse transcriptase inhibitors.

Xu HT, Colby-Germinario SP, Oliveira M, Rajotte D, Bethell R, Wainberg MA.

Antimicrob Agents Chemother. 2014 Aug;58(8):4515-26. doi: 10.1128/AAC.02729-14. Epub 2014 May 27.

PMID:
24867966
[PubMed - in process]
18.

Logeracemin A, an anti-HIV Daphniphyllum alkaloid dimer with a new carbon skeleton from Daphniphyllum longeracemosum.

Xu JB, Zhang H, Gan LS, Han YS, Wainberg MA, Yue JM.

J Am Chem Soc. 2014 May 28;136(21):7631-3. doi: 10.1021/ja503995b. Epub 2014 May 16.

PMID:
24828017
[PubMed - in process]
19.

Has the time come to abandon efavirenz for first-line antiretroviral therapy?

Raffi F, Pozniak AL, Wainberg MA.

J Antimicrob Chemother. 2014 Jul;69(7):1742-7. doi: 10.1093/jac/dku058. Epub 2014 Mar 5.

PMID:
24603962
[PubMed - in process]
20.

Integrase strand transfer inhibitors in the management of HIV-positive individuals.

Mesplède T, Quashie PK, Zanichelli V, Wainberg MA.

Ann Med. 2014 May;46(3):123-9. doi: 10.3109/07853890.2014.883169. Epub 2014 Mar 3.

PMID:
24579911
[PubMed - in process]
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