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Results: 1 to 20 of 591

1.

Integrase Strand Transfer Inhibitors in HIV Therapy.

Mesplède T, Wainberg MA.

Infect Dis Ther. 2013 Dec;2(2):83-93. doi: 10.1007/s40121-013-0020-8. Epub 2013 Nov 19.

PMID:
25134473
[PubMed]
2.

The 20th International AIDS Conference: where do we go from here?

Wainberg MA, Kippax S, Bras M, Salif Sow P.

J Int AIDS Soc. 2014 Jul 18;17(1):19331. doi: 10.7448/IAS.17.1.19331. eCollection 2014. No abstract available.

PMID:
25043381
[PubMed - in process]
Free PMC Article
3.

Do HIV-1 non-B subtypes differentially impact resistance mutations and clinical disease progression in treated populations? Evidence from a systematic review.

Bhargava M, Cajas JM, Wainberg MA, Klein MB, Pant Pai N.

J Int AIDS Soc. 2014 Jul 4;17:18944. doi: 10.7448/IAS.17.1.18944. eCollection 2014.

PMID:
24998532
[PubMed - in process]
Free PMC Article
4.

Effect of HIV-1 Integrase Resistance Mutations When Introduced into SIVmac239 on Susceptibility to Integrase Strand Transfer Inhibitors.

Hassounah SA, Mesplède T, Quashie PK, Oliveira M, Sandstrom PA, Wainberg MA.

J Virol. 2014 Sep 1;88(17):9683-92. doi: 10.1128/JVI.00947-14. Epub 2014 Jun 11.

PMID:
24920794
[PubMed - in process]
5.

Addition of E138K to R263K in HIV integrase increases resistance to dolutegravir, but fails to restore activity of the HIV integrase enzyme and viral replication capacity.

Mesplède T, Osman N, Wares M, Quashie PK, Hassounah S, Anstett K, Han Y, Singhroy DN, Wainberg MA.

J Antimicrob Chemother. 2014 Jun 10. pii: dku199. [Epub ahead of print]

PMID:
24917583
[PubMed - as supplied by publisher]
6.

Exposure to Entry Inhibitors Alters HIV Infectiousness and Sensitivity to Broadly Neutralizing Monoclonal Antibodies.

Kramer VG, Varsaneux O, Oliviera M, Colby-Germinario SP, Mesplède T, Wainberg MA.

J Acquir Immune Defic Syndr. 2014 Sep 1;67(1):7-14. doi: 10.1097/QAI.0000000000000223.

PMID:
24872133
[PubMed - in process]
7.

Effects of the W153L Substitution in HIV Reverse Transcriptase on Viral Replication and Drug Resistance to Multiple Categories of Reverse Transcriptase Inhibitors.

Xu HT, Colby-Germinario SP, Oliveira M, Rajotte D, Bethell R, Wainberg MA.

Antimicrob Agents Chemother. 2014 Aug;58(8):4515-26. doi: 10.1128/AAC.02729-14. Epub 2014 May 27.

PMID:
24867966
[PubMed - in process]
8.

Biochemical Analysis of the Role of G118R-Linked Dolutegravir Drug Resistance Substitutions in HIV-1 Integrase.

Quashie PK, Mesplède T, Han YS, Veres T, Osman N, Hassounah S, Sloan RD, Xu HT, Wainberg MA.

Antimicrob Agents Chemother. 2014 Jun;58(6):3580. doi: 10.1128/AAC.02916-14. No abstract available.

PMID:
24829392
[PubMed - in process]
Free PMC Article
9.

Logeracemin A, an anti-HIV Daphniphyllum alkaloid dimer with a new carbon skeleton from Daphniphyllum longeracemosum.

Xu JB, Zhang H, Gan LS, Han YS, Wainberg MA, Yue JM.

J Am Chem Soc. 2014 May 28;136(21):7631-3. doi: 10.1021/ja503995b. Epub 2014 May 16.

PMID:
24828017
[PubMed - in process]
10.

Has the time come to abandon efavirenz for first-line antiretroviral therapy?

Raffi F, Pozniak AL, Wainberg MA.

J Antimicrob Chemother. 2014 Jul;69(7):1742-7. doi: 10.1093/jac/dku058. Epub 2014 Mar 5.

PMID:
24603962
[PubMed - in process]
11.

Integrase strand transfer inhibitors in the management of HIV-positive individuals.

Mesplède T, Quashie PK, Zanichelli V, Wainberg MA.

Ann Med. 2014 May;46(3):123-9. doi: 10.3109/07853890.2014.883169. Epub 2014 Mar 3.

PMID:
24579911
[PubMed - in process]
12.

Resistance mutations against dolutegravir in HIV integrase impair the emergence of resistance against reverse transcriptase inhibitors.

Oliveira M, Mesplède T, Quashie PK, Moïsi D, Wainberg MA.

AIDS. 2014 Mar 27;28(6):813-9. doi: 10.1097/QAD.0000000000000199.

PMID:
24463394
[PubMed - in process]
13.

The M50I polymorphic substitution in association with the R263K mutation in HIV-1 subtype B integrase increases drug resistance but does not restore viral replicative fitness.

Wares M, Mesplède T, Quashie PK, Osman N, Han Y, Wainberg MA.

Retrovirology. 2014 Jan 17;11:7. doi: 10.1186/1742-4690-11-7.

PMID:
24433497
[PubMed - in process]
Free PMC Article
14.

Targeting host nucleotide biosynthesis with resveratrol inhibits emtricitabine-resistant HIV-1.

Heredia A, Davis C, Amin MN, Le NM, Wainberg MA, Oliveira M, Deeks SG, Wang LX, Redfield RR.

AIDS. 2014 Jan 28;28(3):317-23. doi: 10.1097/QAD.0000000000000168.

PMID:
24326355
[PubMed - in process]
15.

What if HIV were unable to develop resistance against a new therapeutic agent?

Wainberg MA, Mesplède T, Raffi F.

BMC Med. 2013 Nov 22;11:249. doi: 10.1186/1741-7015-11-249.

PMID:
24267867
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

World AIDS Day: together we will stop HIV transmission and conquer AIDS.

Wainberg MA, Lever A.

Retrovirology. 2013 Nov 15;10:129. doi: 10.1186/1742-4690-10-129. No abstract available.

PMID:
24229411
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The connection domain mutation N348I in HIV-1 reverse transcriptase enhances resistance to etravirine and rilpivirine but restricts the emergence of the E138K resistance mutation by diminishing viral replication capacity.

Xu HT, Colby-Germinario SP, Oliveira M, Han Y, Quan Y, Zanichelli V, Wainberg MA.

J Virol. 2014 Feb;88(3):1536-47. doi: 10.1128/JVI.02904-13. Epub 2013 Nov 13.

PMID:
24227862
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Biochemical analysis of the role of G118R-linked dolutegravir drug resistance substitutions in HIV-1 integrase.

Quashie PK, Mesplède T, Han YS, Veres T, Osman N, Hassounah S, Sloan RD, Xu HT, Wainberg MA.

Antimicrob Agents Chemother. 2013 Dec;57(12):6223-35. doi: 10.1128/AAC.01835-13. Epub 2013 Sep 30. Erratum in: Antimicrob Agents Chemother. 2014 Jan;58(1):633.

PMID:
24080645
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Role of the K101E substitution in HIV-1 reverse transcriptase in resistance to rilpivirine and other nonnucleoside reverse transcriptase inhibitors.

Xu HT, Colby-Germinario SP, Huang W, Oliveira M, Han Y, Quan Y, Petropoulos CJ, Wainberg MA.

Antimicrob Agents Chemother. 2013 Nov;57(11):5649-57. doi: 10.1128/AAC.01536-13. Epub 2013 Sep 3.

PMID:
24002090
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Defective HIV-1 quasispecies in the form of multiply drug-resistant proviral DNA within cells can be rescued by superinfection with different subtype variants of HIV-1 and by HIV-2 and SIV.

Quan Y, Xu H, Wainberg MA.

J Antimicrob Chemother. 2014 Jan;69(1):21-7. doi: 10.1093/jac/dkt326. Epub 2013 Aug 20.

PMID:
23963235
[PubMed - indexed for MEDLINE]

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