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Results: 1 to 20 of 44


The tyrosine phosphatase SHP-1 regulates hypoxia inducible factor-1α (HIF-1α) protein levels in endothelial cells under hypoxia.

Alig SK, Stampnik Y, Pircher J, Rotter R, Gaitzsch E, Ribeiro A, Wörnle M, Krötz F, Mannell H.

PLoS One. 2015 Mar 23;10(3):e0121113. doi: 10.1371/journal.pone.0121113. eCollection 2015.


Hepatitis C virus induced endothelial inflammatory response depends on the functional expression of TNFα receptor subtype 2.

Pircher J, Czermak T, Merkle M, Mannell H, Krötz F, Ribeiro A, Vielhauer V, Nadjiri J, Gaitzsch E, Niemeyer M, Porubsky S, Gröne HJ, Wörnle M.

PLoS One. 2014 Nov 24;9(11):e113351. doi: 10.1371/journal.pone.0113351. eCollection 2014.


Viral nucleic acid recognition in human nonimmune cells: in vitro systems.

Ribeiro A, Wörnle M.

Methods Mol Biol. 2014;1169:67-75. doi: 10.1007/978-1-4939-0882-0_7.


Renal lipidosis in patients enrolled in a methadone substitution program.

Porubsky S, Kuppe C, Maier T, Birk HW, Wörnle M, Moeller MJ, Floege J, Gröne HJ.

Arch Pathol Lab Med. 2014 May;138(5):689-93. doi: 10.5858/arpa.2013-0075-CR.


The endothelial tyrosine phosphatase SHP-1 plays an important role for vascular haemostasis in TNFα -induced inflammation in vivo.

Koch E, Pircher J, Czermak T, Gaitzsch E, Alig S, Mannell H, Niemeyer M, Krötz F, Wörnle M.

Mediators Inflamm. 2013;2013:279781. doi: 10.1155/2013/279781. Epub 2013 May 9.


PAR-1 mediates the thrombin-induced mesothelial cell overproduction of VEGF and PAI-1.

Belling F, Ribeiro A, Wörnle M, Ladurner R, Mussack T, Sitter T, Sauter M.

Int J Artif Organs. 2013 Feb;36(2):97-104. doi: 10.5301/ijao.5000174.


Prothrombotic effects of tumor necrosis factor alpha in vivo are amplified by the absence of TNF-alpha receptor subtype 1 and require TNF-alpha receptor subtype 2.

Pircher J, Merkle M, Wörnle M, Ribeiro A, Czermak T, Stampnik Y, Mannell H, Niemeyer M, Vielhauer V, Krötz F.

Arthritis Res Ther. 2012 Oct 18;14(5):R225. doi: 10.1186/ar4064.


Hydrogen sulfide-releasing aspirin derivative ACS14 exerts strong antithrombotic effects in vitro and in vivo.

Pircher J, Fochler F, Czermak T, Mannell H, Kraemer BF, Wörnle M, Sparatore A, Del Soldato P, Pohl U, Krötz F.

Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):2884-91. doi: 10.1161/ATVBAHA.112.300627. Epub 2012 Sep 27.


TNFα enhances TLR3-dependent effects on MMP-9 expression in human mesangial cells.

Merkle M, Ribeiro A, Köppel S, Wörnle M.

Cell Biol Int. 2012;36(12):1155-60. doi: 10.1042/CBI20120282.


Response of VEGF to activation of viral receptors and TNFα in human mesangial cells.

Merkle M, Ribeiro A, Belling F, Mannell H, Krötz F, Pircher J, Wörnle M.

Mol Cell Biochem. 2012 Nov;370(1-2):151-61. doi: 10.1007/s11010-012-1406-8. Epub 2012 Aug 5.


Peritoneal infection and inflammation.

Aufricht C, Neuhofer W, Topley N, Wörnle M.

Mediators Inflamm. 2012;2012:456985. doi: 10.1155/2012/456985. Epub 2012 Jun 7. No abstract available.


Sclerosing peritonitis: a rare but fatal complication of peritoneal inflammation.

Merkle M, Wörnle M.

Mediators Inflamm. 2012;2012:709673. doi: 10.1155/2012/709673. Epub 2012 Mar 26.


Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells.

Djafarzadeh R, Sauter M, Notohamiprodjo S, Noessner E, Goyal P, Siess W, Wörnle M, Ribeiro A, Himmelein S, Sitter T, Nelson PJ.

PLoS One. 2012;7(4):e33963. doi: 10.1371/journal.pone.0033963. Epub 2012 Apr 27.


Activation of peroxisome proliferator-activated receptor-gamma by glitazones reduces the expression and release of monocyte chemoattractant protein-1 in human mesothelial cells.

Sauter M, Kastenmüller K, Belling F, Wörnle M, Ladurner R, Mussack T, Sitter T.

Mediators Inflamm. 2012;2012:217696. doi: 10.1155/2012/217696. Epub 2012 Feb 7.


Site directed vascular gene delivery in vivo by ultrasonic destruction of magnetic nanoparticle coated microbubbles.

Mannell H, Pircher J, Fochler F, Stampnik Y, Räthel T, Gleich B, Plank C, Mykhaylyk O, Dahmani C, Wörnle M, Ribeiro A, Pohl U, Krötz F.

Nanomedicine. 2012 Nov;8(8):1309-18. doi: 10.1016/j.nano.2012.03.007. Epub 2012 Apr 2.


TLR3-dependent immune regulatory functions of human mesangial cells.

Merkle M, Ribeiro A, Köppel S, Pircher J, Mannell H, Roeder M, Wörnle M.

Cell Mol Immunol. 2012 Jul;9(4):334-40. doi: 10.1038/cmi.2012.3. Epub 2012 Apr 2.


Activation of innate immune defense mechanisms contributes to polyomavirus BK-associated nephropathy.

Ribeiro A, Wörnle M, Motamedi N, Anders HJ, Gröne EF, Nitschko H, Kurktschiev P, Debiec H, Kretzler M, Cohen CD, Gröne HJ, Schlöndorff D, Schmid H.

Kidney Int. 2012 Jan;81(1):100-11. doi: 10.1038/ki.2011.311. Epub 2011 Sep 14.


Inhibition of TLR3-mediated proinflammatory effects by Alkylphosphocholines in human retinal pigment epithelial cells.

Wörnle M, Merkle M, Wolf A, Ribeiro A, Himmelein S, Kernt M, Kampik A, Eibl-Lindner KH.

Invest Ophthalmol Vis Sci. 2011 Aug 17;52(9):6536-44. doi: 10.1167/iovs.10-6993.


TLR3-dependent regulation of cytokines in human mesangial cells: a novel role for IP-10 and TNF-alpha in hepatitis C-associated glomerulonephritis.

Merkle M, Ribeiro A, Wörnle M.

Am J Physiol Renal Physiol. 2011 Jul;301(1):F57-69. doi: 10.1152/ajprenal.00083.2011. Epub 2011 Mar 30.


Synthetic double-stranded RNA stimulates the expression of interferon-inducible protein 10 in human mesothelial cells.

Merkle M, Sauter M, Ribeiro A, Mussack T, Ladurner R, Sitter T, Wörnle M.

Clin Vaccine Immunol. 2011 Jan;18(1):176-9. doi: 10.1128/CVI.00007-10. Epub 2010 Nov 24.

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