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Items: 1 to 20 of 23


Reconciling Longitudinal Naive T-Cell and TREC Dynamics during HIV-1 Infection.

Drylewicz J, Vrisekoop N, Mugwagwa T, de Boer AB, Otto SA, Hazenberg MD, Tesselaar K, de Boer RJ, Borghans JA.

PLoS One. 2016 Mar 24;11(3):e0152513. doi: 10.1371/journal.pone.0152513. eCollection 2016.


Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity.

Beerling E, Seinstra D, de Wit E, Kester L, van der Velden D, Maynard C, Schäfer R, van Diest P, Voest E, van Oudenaarden A, Vrisekoop N, van Rheenen J.

Cell Rep. 2016 Mar 15;14(10):2281-8. doi: 10.1016/j.celrep.2016.02.034. Epub 2016 Mar 3.


Quantification of naive and memory T-cell turnover during HIV-1 infection.

Vrisekoop N, Drylewicz J, Van Gent R, Mugwagwa T, Van Lelyveld SF, Veel E, Otto SA, Ackermans MT, Vermeulen JN, Huidekoper HH, Prins JM, Miedema F, de Boer RJ, Tesselaar K, Borghans JA.

AIDS. 2015 Oct 23;29(16):2071-80. doi: 10.1097/QAD.0000000000000822.


Revisiting thymic positive selection and the mature T cell repertoire for antigen.

Vrisekoop N, Monteiro JP, Mandl JN, Germain RN.

Immunity. 2014 Aug 21;41(2):181-90. doi: 10.1016/j.immuni.2014.07.007.


Pathogen-related differences in the abundance of presented antigen are reflected in CD4+ T cell dynamic behavior and effector function in the lung.

Torabi-Parizi P, Vrisekoop N, Kastenmuller W, Gerner MY, Egen JG, Germain RN.

J Immunol. 2014 Feb 15;192(4):1651-60. doi: 10.4049/jimmunol.1301743. Epub 2014 Jan 15.


The mechanisms and physiological relevance of glycocalyx degradation in hepatic ischemia/reperfusion injury.

van Golen RF, Reiniers MJ, Vrisekoop N, Zuurbier CJ, Olthof PB, van Rheenen J, van Gulik TM, Parsons BJ, Heger M.

Antioxid Redox Signal. 2014 Sep 1;21(7):1098-118. doi: 10.1089/ars.2013.5751. Epub 2014 Feb 19. Review.


In vivo imaging and histochemistry are combined in the cryosection labelling and intravital microscopy technique.

Ritsma L, Vrisekoop N, van Rheenen J.

Nat Commun. 2013;4:2366. doi: 10.1038/ncomms3366.


T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens.

Mandl JN, Monteiro JP, Vrisekoop N, Germain RN.

Immunity. 2013 Feb 21;38(2):263-74. doi: 10.1016/j.immuni.2012.09.011. Epub 2013 Jan 3.


Intravital imaging of cancer stem cell plasticity in mammary tumors.

Zomer A, Ellenbroek SI, Ritsma L, Beerling E, Vrisekoop N, Van Rheenen J.

Stem Cells. 2013 Mar;31(3):602-6. doi: 10.1002/stem.1296.


Intravital microscopy through an abdominal imaging window reveals a pre-micrometastasis stage during liver metastasis.

Ritsma L, Steller EJ, Beerling E, Loomans CJ, Zomer A, Gerlach C, Vrisekoop N, Seinstra D, van Gurp L, Schäfer R, Raats DA, de Graaff A, Schumacher TN, de Koning EJ, Rinkes IH, Kranenburg O, van Rheenen J.

Sci Transl Med. 2012 Oct 31;4(158):158ra145. doi: 10.1126/scitranslmed.3004394.


Quantification of lymph node transit times reveals differences in antigen surveillance strategies of naive CD4+ and CD8+ T cells.

Mandl JN, Liou R, Klauschen F, Vrisekoop N, Monteiro JP, Yates AJ, Huang AY, Germain RN.

Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):18036-41. doi: 10.1073/pnas.1211717109. Epub 2012 Oct 15.


Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans.

den Braber I, Mugwagwa T, Vrisekoop N, Westera L, Mögling R, de Boer AB, Willems N, Schrijver EH, Spierenburg G, Gaiser K, Mul E, Otto SA, Ruiter AF, Ackermans MT, Miedema F, Borghans JA, de Boer RJ, Tesselaar K.

Immunity. 2012 Feb 24;36(2):288-97. doi: 10.1016/j.immuni.2012.02.006.


Intravital microscopy: new insights into metastasis of tumors.

Beerling E, Ritsma L, Vrisekoop N, Derksen PW, van Rheenen J.

J Cell Sci. 2011 Feb 1;124(Pt 3):299-310. doi: 10.1242/jcs.072728. Review.


In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days.

Pillay J, den Braber I, Vrisekoop N, Kwast LM, de Boer RJ, Borghans JA, Tesselaar K, Koenderman L.

Blood. 2010 Jul 29;116(4):625-7. doi: 10.1182/blood-2010-01-259028. Epub 2010 Apr 21.


Life and death as a T lymphocyte: from immune protection to HIV pathogenesis.

Vrisekoop N, Mandl JN, Germain RN.

J Biol. 2009;8(10):91. doi: 10.1186/jbiol198. Epub . Review.


HIV-1 can persist in aged memory CD4+ T lymphocytes with minimal signs of evolution after 8.3 years of effective highly active antiretroviral therapy.

Nottet HS, van Dijk SJ, Fanoy EB, Goedegebuure IW, de Jong D, Vrisekoop N, van Baarle D, Boltz V, Palmer S, Borleffs JC, Boucher CA.

J Acquir Immune Defic Syndr. 2009 Apr 1;50(4):345-53. doi: 10.1097/QAI.0b013e318197eb04.


In vivo dynamics of stable chronic lymphocytic leukemia inversely correlate with somatic hypermutation levels and suggest no major leukemic turnover in bone marrow.

van Gent R, Kater AP, Otto SA, Jaspers A, Borghans JA, Vrisekoop N, Ackermans MA, Ruiter AF, Wittebol S, Eldering E, van Oers MH, Tesselaar K, Kersten MJ, Miedema F.

Cancer Res. 2008 Dec 15;68(24):10137-44. doi: 10.1158/0008-5472.CAN-08-2325.


Restoration of the CD4 T cell compartment after long-term highly active antiretroviral therapy without phenotypical signs of accelerated immunological aging.

Vrisekoop N, van Gent R, de Boer AB, Otto SA, Borleffs JC, Steingrover R, Prins JM, Kuijpers TW, Wolfs TF, Geelen SP, Vulto I, Lansdorp P, Tesselaar K, Borghans JA, Miedema F.

J Immunol. 2008 Jul 15;181(2):1573-81.


Sparse production but preferential incorporation of recently produced naive T cells in the human peripheral pool.

Vrisekoop N, den Braber I, de Boer AB, Ruiter AF, Ackermans MT, van der Crabben SN, Schrijver EH, Spierenburg G, Sauerwein HP, Hazenberg MD, de Boer RJ, Miedema F, Borghans JA, Tesselaar K.

Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6115-20. doi: 10.1073/pnas.0709713105. Epub 2008 Apr 17.


Mitochondrial DNA decline in T cells of HIV-1 seroconverters may be dependent on immune activation.

Casula M, Vrisekoop N, Wit FW, de Baar MP, de Ronde A, Miedema F, Reiss P.

J Infect Dis. 2007 Aug 1;196(3):371-6. Epub 2007 Jun 15.

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