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Uremic Toxicity of Advanced Glycation End Products in CKD.

Stinghen AE, Massy ZA, Vlassara H, Striker GE, Boullier A.

J Am Soc Nephrol. 2016 Feb;27(2):354-70. doi: 10.1681/ASN.2014101047. Epub 2015 Aug 26. Review.


Diabetes Mellitus 2014.

Migdalis I, Leslie D, Mavrogiannaki A, Papanas N, Valensi P, Vlassara H.

Int J Endocrinol. 2015;2015:845759. doi: 10.1155/2015/845759. Epub 2015 May 25. No abstract available.


Effects of sevelamer carbonate on advanced glycation end products and antioxidant/pro-oxidant status in patients with diabetic kidney disease.

Yubero-Serrano EM, Woodward M, Poretsky L, Vlassara H, Striker GE; AGE-less Study Group.

Clin J Am Soc Nephrol. 2015 May 7;10(5):759-66. doi: 10.2215/CJN.07750814. Epub 2015 Feb 20.


Elevated serum advanced glycation endproducts in obese indicate risk for the metabolic syndrome: a link between healthy and unhealthy obesity?

Uribarri J, Cai W, Woodward M, Tripp E, Goldberg L, Pyzik R, Yee K, Tansman L, Chen X, Mani V, Fayad ZA, Vlassara H.

J Clin Endocrinol Metab. 2015 May;100(5):1957-66. doi: 10.1210/jc.2014-3925. Epub 2015 Feb 19.


Chronic ingestion of advanced glycation end products induces degenerative spinal changes and hypertrophy in aging pre-diabetic mice.

Illien-Jünger S, Lu Y, Qureshi SA, Hecht AC, Cai W, Vlassara H, Striker GE, Iatridis JC.

PLoS One. 2015 Feb 10;10(2):e0116625. doi: 10.1371/journal.pone.0116625. eCollection 2015.


Dietary consumption of advanced glycation end products and pancreatic cancer in the prospective NIH-AARP Diet and Health Study.

Jiao L, Stolzenberg-Solomon R, Zimmerman TP, Duan Z, Chen L, Kahle L, Risch A, Subar AF, Cross AJ, Hollenbeck A, Vlassara H, Striker G, Sinha R.

Am J Clin Nutr. 2015 Jan;101(1):126-34. doi: 10.3945/ajcn.114.098061. Epub 2014 Nov 19.


Dietary advanced glycation end products are associated with decline in memory in young elderly.

West RK, Moshier E, Lubitz I, Schmeidler J, Godbold J, Cai W, Uribarri J, Vlassara H, Silverman JM, Beeri MS.

Mech Ageing Dev. 2014 Sep;140:10-2. doi: 10.1016/j.mad.2014.07.001. Epub 2014 Jul 15.


Diabetes mellitus.

Migdalis I, Leslie D, Papanas N, Valensi P, Vlassara H.

Int J Endocrinol. 2014;2014:108419. doi: 10.1155/2014/108419. Epub 2014 Jan 23. No abstract available.


Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans.

Cai W, Uribarri J, Zhu L, Chen X, Swamy S, Zhao Z, Grosjean F, Simonaro C, Kuchel GA, Schnaider-Beeri M, Woodward M, Striker GE, Vlassara H.

Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4940-5. doi: 10.1073/pnas.1316013111. Epub 2014 Feb 24.


Advanced glycation end products (AGE) and diabetes: cause, effect, or both?

Vlassara H, Uribarri J.

Curr Diab Rep. 2014 Jan;14(1):453. doi: 10.1007/s11892-013-0453-1. Review.


Advanced glycation endproducts in diabetes and diabetic complications.

Vlassara H, Striker GE.

Endocrinol Metab Clin North Am. 2013 Dec;42(4):697-719. doi: 10.1016/j.ecl.2013.07.005. Review.


Combined anti-inflammatory and anti-AGE drug treatments have a protective effect on intervertebral discs in mice with diabetes.

Illien-Junger S, Grosjean F, Laudier DM, Vlassara H, Striker GE, Iatridis JC.

PLoS One. 2013 May 17;8(5):e64302. doi: 10.1371/journal.pone.0064302. Print 2013. Erratum in: PLoS One. 2015;10(3):e0119112.


Suppression of native defense mechanisms, SIRT1 and PPARγ, by dietary glycoxidants precedes disease in adult humans; relevance to lifestyle-engendered chronic diseases.

Uribarri J, Cai W, Pyzik R, Goodman S, Chen X, Zhu L, Ramdas M, Striker GE, Vlassara H.

Amino Acids. 2014 Feb;46(2):301-9. doi: 10.1007/s00726-013-1502-4. Epub 2013 May 1.


Increased circulating advanced glycation endproducts (AGEs) in acute trauma patients.

Schulman CI, Uribarri J, Cai W, Manning R, Landy DC, Gallardo M, Castillo A, Namias N, Striker GE, Livingstone A, Vlassara H.

Clin Chem Lab Med. 2014 Jan 1;52(1):103-8. doi: 10.1515/cclm-2012-0834.


Pentosan polysulfate: a novel therapy for the mucopolysaccharidoses.

Schuchman EH, Ge Y, Lai A, Borisov Y, Faillace M, Eliyahu E, He X, Iatridis J, Vlassara H, Striker G, Simonaro CM.

PLoS One. 2013;8(1):e54459. doi: 10.1371/journal.pone.0054459. Epub 2013 Jan 24.


Managing chronic inflammation in the aging diabetic patient with CKD by diet or sevelamer carbonate: a modern paradigm shift.

Vlassara H, Cai W, Chen X, Serrano EJ, Shobha MS, Uribarri J, Woodward M, Striker GE.

J Gerontol A Biol Sci Med Sci. 2012 Dec;67(12):1410-6. doi: 10.1093/gerona/gls195. Epub 2012 Oct 29. Review.


Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1.

Cai W, Ramdas M, Zhu L, Chen X, Striker GE, Vlassara H.

Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15888-93. Epub 2012 Aug 20.


Effect of dietary advanced glycation end products on mouse liver.

Patel R, Baker SS, Liu W, Desai S, Alkhouri R, Kozielski R, Mastrandrea L, Sarfraz A, Cai W, Vlassara H, Patel MS, Baker RD, Zhu L.

PLoS One. 2012;7(4):e35143. doi: 10.1371/journal.pone.0035143. Epub 2012 Apr 4.


Effects of sevelamer on HbA1c, inflammation, and advanced glycation end products in diabetic kidney disease.

Vlassara H, Uribarri J, Cai W, Goodman S, Pyzik R, Post J, Grosjean F, Woodward M, Striker GE.

Clin J Am Soc Nephrol. 2012 Jun;7(6):934-42. doi: 10.2215/CJN.12891211. Epub 2012 Mar 29.


Serum concentration of an inflammatory glycotoxin, methylglyoxal, is associated with increased cognitive decline in elderly individuals.

Beeri MS, Moshier E, Schmeidler J, Godbold J, Uribarri J, Reddy S, Sano M, Grossman HT, Cai W, Vlassara H, Silverman JM.

Mech Ageing Dev. 2011 Nov-Dec;132(11-12):583-7. doi: 10.1016/j.mad.2011.10.007. Epub 2011 Nov 3.

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