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Results: 1 to 20 of 21

1.

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.

Vizeacoumar FJ, Arnold R, Vizeacoumar FS, Chandrashekhar M, Buzina A, Young JT, Kwan JH, Sayad A, Mero P, Lawo S, Tanaka H, Brown KR, Baryshnikova A, Mak AB, Fedyshyn Y, Wang Y, Brito GC, Kasimer D, Makhnevych T, Ketela T, Datti A, Babu M, Emili A, Pelletier L, Wrana J, Wainberg Z, Kim PM, Rottapel R, O'Brien CA, Andrews B, Boone C, Moffat J.

Mol Syst Biol. 2013 Oct 8;9:696. doi: 10.1038/msb.2013.54.

PMID:
24104479
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pH(c) in Saccharomyces cerevisiae.

Orij R, Urbanus ML, Vizeacoumar FJ, Giaever G, Boone C, Nislow C, Brul S, Smits GJ.

Genome Biol. 2012 Sep 10;13(9):R80. doi: 10.1186/gb-2012-13-9-r80.

PMID:
23021432
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Interaction landscape of membrane-protein complexes in Saccharomyces cerevisiae.

Babu M, Vlasblom J, Pu S, Guo X, Graham C, Bean BD, Burston HE, Vizeacoumar FJ, Snider J, Phanse S, Fong V, Tam YY, Davey M, Hnatshak O, Bajaj N, Chandran S, Punna T, Christopolous C, Wong V, Yu A, Zhong G, Li J, Stagljar I, Conibear E, Wodak SJ, Emili A, Greenblatt JF.

Nature. 2012 Sep 27;489(7417):585-9. doi: 10.1038/nature11354. Epub 2012 Sep 2.

PMID:
22940862
[PubMed - indexed for MEDLINE]
4.

Hsp110 is required for spindle length control.

Makhnevych T, Wong P, Pogoutse O, Vizeacoumar FJ, Greenblatt JF, Emili A, Houry WA.

J Cell Biol. 2012 Aug 20;198(4):623-36. doi: 10.1083/jcb.201111105.

PMID:
22908312
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Essential gene profiles in breast, pancreatic, and ovarian cancer cells.

Marcotte R, Brown KR, Suarez F, Sayad A, Karamboulas K, Krzyzanowski PM, Sircoulomb F, Medrano M, Fedyshyn Y, Koh JL, van Dyk D, Fedyshyn B, Luhova M, Brito GC, Vizeacoumar FJ, Vizeacoumar FS, Datti A, Kasimer D, Buzina A, Mero P, Misquitta C, Normand J, Haider M, Ketela T, Wrana JL, Rottapel R, Neel BG, Moffat J.

Cancer Discov. 2012 Feb;2(2):172-89. doi: 10.1158/2159-8290.CD-11-0224. Epub 2011 Dec 29.

PMID:
22585861
[PubMed - indexed for MEDLINE]
6.

PhenoM: a database of morphological phenotypes caused by mutation of essential genes in Saccharomyces cerevisiae.

Jin K, Li J, Vizeacoumar FS, Li Z, Min R, Zamparo L, Vizeacoumar FJ, Datti A, Andrews B, Boone C, Zhang Z.

Nucleic Acids Res. 2012 Jan;40(Database issue):D687-94. doi: 10.1093/nar/gkr827. Epub 2011 Oct 18.

PMID:
22009677
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Systematic exploration of essential yeast gene function with temperature-sensitive mutants.

Li Z, Vizeacoumar FJ, Bahr S, Li J, Warringer J, Vizeacoumar FS, Min R, Vandersluis B, Bellay J, Devit M, Fleming JA, Stephens A, Haase J, Lin ZY, Baryshnikova A, Lu H, Yan Z, Jin K, Barker S, Datti A, Giaever G, Nislow C, Bulawa C, Myers CL, Costanzo M, Gingras AC, Zhang Z, Blomberg A, Bloom K, Andrews B, Boone C.

Nat Biotechnol. 2011 Apr;29(4):361-7. doi: 10.1038/nbt.1832. Epub 2011 Mar 27.

PMID:
21441928
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Genetic interactions reveal the evolutionary trajectories of duplicate genes.

VanderSluis B, Bellay J, Musso G, Costanzo M, Papp B, Vizeacoumar FJ, Baryshnikova A, Andrews B, Boone C, Myers CL.

Mol Syst Biol. 2010 Nov 16;6:429. doi: 10.1038/msb.2010.82.

PMID:
21081923
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Synthetic genetic array (SGA) analysis in Saccharomyces cerevisiae and Schizosaccharomyces pombe.

Baryshnikova A, Costanzo M, Dixon S, Vizeacoumar FJ, Myers CL, Andrews B, Boone C.

Methods Enzymol. 2010;470:145-79. doi: 10.1016/S0076-6879(10)70007-0. Epub 2010 Mar 1.

PMID:
20946810
[PubMed - indexed for MEDLINE]
10.

A novel mechanism for SUMO system control: regulated Ulp1 nucleolar sequestration.

Sydorskyy Y, Srikumar T, Jeram SM, Wheaton S, Vizeacoumar FJ, Makhnevych T, Chong YT, Gingras AC, Raught B.

Mol Cell Biol. 2010 Sep;30(18):4452-62. doi: 10.1128/MCB.00335-10. Epub 2010 Jul 20.

PMID:
20647537
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Exploiting the determinants of stochastic gene expression in Saccharomyces cerevisiae for genome-wide prediction of expression noise.

Li J, Min R, Vizeacoumar FJ, Jin K, Xin X, Zhang Z.

Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10472-7. doi: 10.1073/pnas.0914302107. Epub 2010 May 20.

PMID:
20489180
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The genetic landscape of a cell.

Costanzo M, Baryshnikova A, Bellay J, Kim Y, Spear ED, Sevier CS, Ding H, Koh JL, Toufighi K, Mostafavi S, Prinz J, St Onge RP, VanderSluis B, Makhnevych T, Vizeacoumar FJ, Alizadeh S, Bahr S, Brost RL, Chen Y, Cokol M, Deshpande R, Li Z, Lin ZY, Liang W, Marback M, Paw J, San Luis BJ, Shuteriqi E, Tong AH, van Dyk N, Wallace IM, Whitney JA, Weirauch MT, Zhong G, Zhu H, Houry WA, Brudno M, Ragibizadeh S, Papp B, Pál C, Roth FP, Giaever G, Nislow C, Troyanskaya OG, Bussey H, Bader GD, Gingras AC, Morris QD, Kim PM, Kaiser CA, Myers CL, Andrews BJ, Boone C.

Science. 2010 Jan 22;327(5964):425-31. doi: 10.1126/science.1180823.

PMID:
20093466
[PubMed - indexed for MEDLINE]
Free Article
13.

Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis.

Vizeacoumar FJ, van Dyk N, S Vizeacoumar F, Cheung V, Li J, Sydorskyy Y, Case N, Li Z, Datti A, Nislow C, Raught B, Zhang Z, Frey B, Bloom K, Boone C, Andrews BJ.

J Cell Biol. 2010 Jan 11;188(1):69-81. doi: 10.1083/jcb.200909013.

PMID:
20065090
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A picture is worth a thousand words: genomics to phenomics in the yeast Saccharomyces cerevisiae.

Vizeacoumar FJ, Chong Y, Boone C, Andrews BJ.

FEBS Lett. 2009 Jun 5;583(11):1656-61. doi: 10.1016/j.febslet.2009.03.068. Epub 2009 Apr 5. Review.

PMID:
19351535
[PubMed - indexed for MEDLINE]
Free Article
15.

Global map of SUMO function revealed by protein-protein interaction and genetic networks.

Makhnevych T, Sydorskyy Y, Xin X, Srikumar T, Vizeacoumar FJ, Jeram SM, Li Z, Bahr S, Andrews BJ, Boone C, Raught B.

Mol Cell. 2009 Jan 16;33(1):124-35. doi: 10.1016/j.molcel.2008.12.025.

PMID:
19150434
[PubMed - indexed for MEDLINE]
Free Article
16.

Pex19p binds Pex30p and Pex32p at regions required for their peroxisomal localization but separate from their peroxisomal targeting signals.

Vizeacoumar FJ, Vreden WN, Aitchison JD, Rachubinski RA.

J Biol Chem. 2006 May 26;281(21):14805-12. Epub 2006 Mar 21.

PMID:
16551610
[PubMed - indexed for MEDLINE]
Free Article
17.

The dynamin-like protein Vps1p of the yeast Saccharomyces cerevisiae associates with peroxisomes in a Pex19p-dependent manner.

Vizeacoumar FJ, Vreden WN, Fagarasanu M, Eitzen GA, Aitchison JD, Rachubinski RA.

J Biol Chem. 2006 May 5;281(18):12817-23. Epub 2006 Mar 6.

PMID:
16520372
[PubMed - indexed for MEDLINE]
Free Article
18.

Pex30p, Pex31p, and Pex32p form a family of peroxisomal integral membrane proteins regulating peroxisome size and number in Saccharomyces cerevisiae.

Vizeacoumar FJ, Torres-Guzman JC, Bouard D, Aitchison JD, Rachubinski RA.

Mol Biol Cell. 2004 Feb;15(2):665-77. Epub 2003 Nov 14.

PMID:
14617799
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Pex11-related proteins in peroxisome dynamics: a role for the novel peroxin Pex27p in controlling peroxisome size and number in Saccharomyces cerevisiae.

Tam YY, Torres-Guzman JC, Vizeacoumar FJ, Smith JJ, Marelli M, Aitchison JD, Rachubinski RA.

Mol Biol Cell. 2003 Oct;14(10):4089-102. Epub 2003 May 18.

PMID:
14517321
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

YHR150w and YDR479c encode peroxisomal integral membrane proteins involved in the regulation of peroxisome number, size, and distribution in Saccharomyces cerevisiae.

Vizeacoumar FJ, Torres-Guzman JC, Tam YY, Aitchison JD, Rachubinski RA.

J Cell Biol. 2003 Apr 28;161(2):321-32. Epub 2003 Apr 21.

PMID:
12707309
[PubMed - indexed for MEDLINE]
Free PMC Article

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