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Results: 1 to 20 of 35

1.

A human monoclonal IgG that binds aβ assemblies and diverse amyloids exhibits anti-amyloid activities in vitro and in vivo.

Levites Y, O'Nuallain B, Puligedda RD, Ondrejcak T, Adekar SP, Chen C, Cruz PE, Rosario AM, Macy S, Mably AJ, Walsh DM, Vidal R, Solomon A, Brown D, Rowan MJ, Golde TE, Dessain SK.

J Neurosci. 2015 Apr 22;35(16):6265-76. doi: 10.1523/JNEUROSCI.5109-14.2015.

2.

Systemic and cerebral iron homeostasis in ferritin knock-out mice.

Li W, Garringer HJ, Goodwin CB, Richine B, Acton A, VanDuyn N, Muhoberac BB, Irimia-Dominguez J, Chan RJ, Peacock M, Nass R, Ghetti B, Vidal R.

PLoS One. 2015 Jan 28;10(1):e0117435. doi: 10.1371/journal.pone.0117435. eCollection 2015.

3.

Evidence for lymphatic Aβ clearance in Alzheimer's transgenic mice.

Pappolla M, Sambamurti K, Vidal R, Pacheco-Quinto J, Poeggeler B, Matsubara E.

Neurobiol Dis. 2014 Nov;71:215-9. doi: 10.1016/j.nbd.2014.07.012. Epub 2014 Aug 4.

PMID:
25102344
4.

A novel ferritin light chain mutation in neuroferritinopathy with an atypical presentation.

Nishida K, Garringer HJ, Futamura N, Funakawa I, Jinnai K, Vidal R, Takao M.

J Neurol Sci. 2014 Jul 15;342(1-2):173-7. doi: 10.1016/j.jns.2014.03.060. Epub 2014 Apr 12.

5.

Amyloid peptides ABri and ADan show differential neurotoxicity in transgenic Drosophila models of familial British and Danish dementia.

Marcora MS, Fernández-Gamba AC, Avendaño LA, Rotondaro C, Podhajcer OL, Vidal R, Morelli L, Ceriani MF, Castaño EM.

Mol Neurodegener. 2014 Jan 9;9:5. doi: 10.1186/1750-1326-9-5.

6.

Abnormal iron homeostasis and neurodegeneration.

Muhoberac BB, Vidal R.

Front Aging Neurosci. 2013 Jul 30;5:32. doi: 10.3389/fnagi.2013.00032. eCollection 2013.

7.

Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice.

Garringer HJ, Murrell J, Sammeta N, Gnezda A, Ghetti B, Vidal R.

PLoS One. 2013;8(2):e56426. doi: 10.1371/journal.pone.0056426. Epub 2013 Feb 13.

8.

Generation of a novel murine model of Aβ deposition based on the expression of human wild-type amyloid precursor protein gene.

Vidal R, Ghetti B.

Prion. 2012 Sep-Oct;6(4):346-9. doi: 10.4161/pri.21023. Epub 2012 Aug 9.

9.

The Psen1-L166P-knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice.

Vidal R, Sammeta N, Garringer HJ, Sambamurti K, Miravalle L, Lamb BT, Ghetti B.

FASEB J. 2012 Jul;26(7):2899-910. doi: 10.1096/fj.12-205542. Epub 2012 Mar 29.

10.

A mutant light-chain ferritin that causes neurodegeneration has enhanced propensity toward oxidative damage.

Baraibar MA, Barbeito AG, Muhoberac BB, Vidal R.

Free Radic Biol Med. 2012 May 1;52(9):1692-7. doi: 10.1016/j.freeradbiomed.2012.02.015. Epub 2012 Feb 17.

11.

Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice.

Farrow EG, Yu X, Summers LJ, Davis SI, Fleet JC, Allen MR, Robling AG, Stayrook KR, Jideonwo V, Magers MJ, Garringer HJ, Vidal R, Chan RJ, Goodwin CB, Hui SL, Peacock M, White KE.

Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1146-55. doi: 10.1073/pnas.1110905108. Epub 2011 Oct 17.

12.

Characterization of amyloid deposits in neurodegenerative diseases.

Vidal R, Ghetti B.

Methods Mol Biol. 2011;793:241-58. doi: 10.1007/978-1-61779-328-8_16.

PMID:
21913105
13.

Abnormal iron metabolism in fibroblasts from a patient with the neurodegenerative disease hereditary ferritinopathy.

Barbeito AG, Levade T, Delisle MB, Ghetti B, Vidal R.

Mol Neurodegener. 2010 Nov 10;5:50. doi: 10.1186/1750-1326-5-50.

14.

Memory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis.

Tamayev R, Giliberto L, Li W, d'Abramo C, Arancio O, Vidal R, D'Adamio L.

J Neurosci. 2010 Nov 3;30(44):14915-24. doi: 10.1523/JNEUROSCI.3917-10.2010.

15.

Iron loading-induced aggregation and reduction of iron incorporation in heteropolymeric ferritin containing a mutant light chain that causes neurodegeneration.

Muhoberac BB, Baraibar MA, Vidal R.

Biochim Biophys Acta. 2011 Apr;1812(4):544-8. doi: 10.1016/j.bbadis.2010.10.010. Epub 2010 Oct 26.

16.

Accumulation of oxidative DNA damage in brain mitochondria in mouse model of hereditary ferritinopathy.

Deng X, Vidal R, Englander EW.

Neurosci Lett. 2010 Jul 19;479(1):44-8. doi: 10.1016/j.neulet.2010.05.025. Epub 2010 May 15.

17.

Generation and initial characterization of FDD knock in mice.

Giliberto L, Matsuda S, Vidal R, D'Adamio L.

PLoS One. 2009 Nov 18;4(11):e7900. doi: 10.1371/journal.pone.0007900.

18.

Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration.

Baraibar MA, Muhoberac BB, Garringer HJ, Hurley TD, Vidal R.

J Biol Chem. 2010 Jan 15;285(3):1950-6. doi: 10.1074/jbc.M109.042986. Epub 2009 Nov 18.

19.

Modeling familial British and Danish dementia.

Garringer HJ, Murrell J, D'Adamio L, Ghetti B, Vidal R.

Brain Struct Funct. 2010 Mar;214(2-3):235-44. doi: 10.1007/s00429-009-0221-9. Epub 2009 Sep 25. Review.

PMID:
19779737
20.

Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene.

Barbeito AG, Garringer HJ, Baraibar MA, Gao X, Arredondo M, Núñez MT, Smith MA, Ghetti B, Vidal R.

J Neurochem. 2009 May;109(4):1067-78. doi: 10.1111/j.1471-4159.2009.06028.x. Epub 2009 Mar 30.

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