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Results: 19

1.

The PPARα-FGF21 Hormone Axis Contributes to Metabolic Regulation by the Hepatic JNK Signaling Pathway.

Vernia S, Cavanagh-Kyros J, Garcia-Haro L, Sabio G, Barrett T, Jung DY, Kim JK, Xu J, Shulha HP, Garber M, Gao G, Davis RJ.

Cell Metab. 2014 Jul 15. pii: S1550-4131(14)00275-7. doi: 10.1016/j.cmet.2014.06.010. [Epub ahead of print]

PMID:
25043817
[PubMed - as supplied by publisher]
2.

Diet-induced obesity mediated by the JNK/DIO2 signal transduction pathway.

Vernia S, Cavanagh-Kyros J, Barrett T, Jung DY, Kim JK, Davis RJ.

Genes Dev. 2013 Nov 1;27(21):2345-55. doi: 10.1101/gad.223800.113.

PMID:
24186979
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Sumoylation of AMPKβ2 subunit enhances AMP-activated protein kinase activity.

Rubio T, Vernia S, Sanz P.

Mol Biol Cell. 2013 Jun;24(11):1801-11, S1-4. doi: 10.1091/mbc.E12-11-0806. Epub 2013 Apr 3.

PMID:
23552691
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Identification of a novel Pfkfb1 mRNA variant in rat fetal liver.

Cosin-Roger J, Vernia S, Alvarez MS, Cucarella C, Boscá L, Martin-Sanz P, Fernández-Alvarez AJ, Casado M.

Biochem Biophys Res Commun. 2013 Feb 1;431(1):36-40. doi: 10.1016/j.bbrc.2012.12.109. Epub 2013 Jan 3.

PMID:
23291237
[PubMed - indexed for MEDLINE]
5.

Malin knockout mice support a primary role of autophagy in the pathogenesis of Lafora disease.

Knecht E, Criado-García O, Aguado C, Gayarre J, Duran-Trio L, Garcia-Cabrero AM, Vernia S, San Millán B, Heredia M, Romá-Mateo C, Mouron S, Juana-López L, Domínguez M, Navarro C, Serratosa JM, Sanchez M, Sanz P, Bovolenta P, Rodríguez de Córdoba S.

Autophagy. 2012 Apr;8(4):701-3. doi: 10.4161/auto.19522. Epub 2012 Apr 1. Review. Erratum in: Autophagy. 2012 Jul 1;8(7):1163.

PMID:
22361617
[PubMed - indexed for MEDLINE]
6.

Lafora bodies and neurological defects in malin-deficient mice correlate with impaired autophagy.

Criado O, Aguado C, Gayarre J, Duran-Trio L, Garcia-Cabrero AM, Vernia S, San Millán B, Heredia M, Romá-Mateo C, Mouron S, Juana-López L, Domínguez M, Navarro C, Serratosa JM, Sanchez M, Sanz P, Bovolenta P, Knecht E, Rodriguez de Cordoba S.

Hum Mol Genet. 2012 Apr 1;21(7):1521-33. doi: 10.1093/hmg/ddr590. Epub 2011 Dec 20. Erratum in: Hum Mol Genet. 2012 Oct 1;21(19):4366.

PMID:
22186026
[PubMed - indexed for MEDLINE]
Free Article
7.

Lafora disease E3-ubiquitin ligase malin is related to TRIM32 at both the phylogenetic and functional level.

Romá-Mateo C, Moreno D, Vernia S, Rubio T, Bridges TM, Gentry MS, Sanz P.

BMC Evol Biol. 2011 Jul 28;11:225. doi: 10.1186/1471-2148-11-225.

PMID:
21798009
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A PTG variant contributes to a milder phenotype in Lafora disease.

Guerrero R, Vernia S, Sanz R, Abreu-Rodríguez I, Almaraz C, García-Hoyos M, Michelucci R, Tassinari CA, Riguzzi P, Nobile C, Sanz P, Serratosa JM, Gómez-Garre P.

PLoS One. 2011;6(6):e21294. doi: 10.1371/journal.pone.0021294. Epub 2011 Jun 30.

PMID:
21738631
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Lafora progressive myoclonus epilepsy: NHLRC1 mutations affect glycogen metabolism.

Couarch P, Vernia S, Gourfinkel-An I, Lesca G, Gataullina S, Fedirko E, Trouillard O, Depienne C, Dulac O, Steschenko D, Leguern E, Sanz P, Baulac S.

J Mol Med (Berl). 2011 Sep;89(9):915-25. doi: 10.1007/s00109-011-0758-y. Epub 2011 Apr 20.

PMID:
21505799
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Laforin, a dual specificity phosphatase involved in Lafora disease, regulates insulin response and whole-body energy balance in mice.

Vernia S, Heredia M, Criado O, Rodriguez de Cordoba S, Garcia-Roves PM, Cansell C, Denis R, Luquet S, Foufelle F, Ferre P, Sanz P.

Hum Mol Genet. 2011 Jul 1;20(13):2571-84. doi: 10.1093/hmg/ddr157. Epub 2011 Apr 14.

PMID:
21493628
[PubMed - indexed for MEDLINE]
Free Article
11.

Selective role of sterol regulatory element binding protein isoforms in aggregated LDL-induced vascular low density lipoprotein receptor-related protein-1 expression.

Costales P, Aledo R, Vérnia S, Das A, Shah VH, Casado M, Badimon L, Llorente-Cortés V.

Atherosclerosis. 2010 Dec;213(2):458-68. doi: 10.1016/j.atherosclerosis.2010.09.034. Epub 2010 Oct 8.

PMID:
20980003
[PubMed - indexed for MEDLINE]
12.

Impaired autophagy in Lafora disease.

Knecht E, Aguado C, Sarkar S, Korolchuk VI, Criado-García O, Vernia S, Boya P, Sanz P, Rodríguez de Córdoba S, Rubinsztein DC.

Autophagy. 2010 Oct;6(7):991-3. doi: 10.4161/auto6.7.13308. Epub 2010 Oct 11.

PMID:
20818165
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Laforin, the most common protein mutated in Lafora disease, regulates autophagy.

Aguado C, Sarkar S, Korolchuk VI, Criado O, Vernia S, Boya P, Sanz P, de Córdoba SR, Knecht E, Rubinsztein DC.

Hum Mol Genet. 2010 Jul 15;19(14):2867-76. doi: 10.1093/hmg/ddq190. Epub 2010 May 7.

PMID:
20453062
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Increased endoplasmic reticulum stress and decreased proteasomal function in lafora disease models lacking the phosphatase laforin.

Vernia S, Rubio T, Heredia M, Rodríguez de Córdoba S, Sanz P.

PLoS One. 2009 Jun 16;4(6):e5907. doi: 10.1371/journal.pone.0005907.

PMID:
19529779
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

AMP-activated protein kinase phosphorylates R5/PTG, the glycogen targeting subunit of the R5/PTG-protein phosphatase 1 holoenzyme, and accelerates its down-regulation by the laforin-malin complex.

Vernia S, Solaz-Fuster MC, Gimeno-Alcañiz JV, Rubio T, García-Haro L, Foretz M, de Córdoba SR, Sanz P.

J Biol Chem. 2009 Mar 27;284(13):8247-55. doi: 10.1074/jbc.M808492200. Epub 2009 Jan 26.

PMID:
19171932
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A new PCSK9 gene promoter variant affects gene expression and causes autosomal dominant hypercholesterolemia.

Blesa S, Vernia S, Garcia-Garcia AB, Martinez-Hervas S, Ivorra C, Gonzalez-Albert V, Ascaso JF, Martín-Escudero JC, Real JT, Carmena R, Casado M, Chaves FJ.

J Clin Endocrinol Metab. 2008 Sep;93(9):3577-83. doi: 10.1210/jc.2008-0269. Epub 2008 Jun 17. Erratum in: J Clin Endocrinol Metab. 2009 Jan;94(1):325.

PMID:
18559913
[PubMed - indexed for MEDLINE]
17.

A rare missense mutation in a type 2 diabetes patient decreases the transcriptional activity of human sterol regulatory element binding protein-1.

Vernia S, Eberlé D, Hernandez Mijares A, Foufelle F, Casado M.

Hum Mutat. 2006 Feb;27(2):212.

PMID:
16429400
[PubMed - indexed for MEDLINE]
18.

Involvement of peroxynitrite on the early loss of p450 in short-term hepatocyte cultures.

Vernia S, Sanz-González SM, López-García MP.

Adv Exp Med Biol. 2001;500:209-12.

PMID:
11764937
[PubMed - indexed for MEDLINE]
19.

Differential sensitivity of rat hepatocyte CYP isoforms to self-generated nitric oxide.

Vernia S, Beaune P, Coloma J, López-García MP.

FEBS Lett. 2001 Jan 12;488(1-2):59-63.

PMID:
11163796
[PubMed - indexed for MEDLINE]
Free Article

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