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Items: 7

1.

Structural link between γ-aminobutyric acid type A (GABAA) receptor agonist binding site and inner β-sheet governs channel activation and allosteric drug modulation.

Venkatachalan SP, Czajkowski C.

J Biol Chem. 2012 Feb 24;287(9):6714-24. doi: 10.1074/jbc.M111.316836. Epub 2012 Jan 4.

2.

Identification of a fluorescent general anesthetic, 1-aminoanthracene.

Butts CA, Xi J, Brannigan G, Saad AA, Venkatachalan SP, Pearce RA, Klein ML, Eckenhoff RG, Dmochowski IJ.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6501-6. doi: 10.1073/pnas.0810590106. Epub 2009 Apr 3.

3.

A conserved salt bridge critical for GABA(A) receptor function and loop C dynamics.

Venkatachalan SP, Czajkowski C.

Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13604-9. doi: 10.1073/pnas.0801854105. Epub 2008 Aug 29. Erratum in: Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6423.

4.

Optimized expression vector for ion channel studies in Xenopus oocytes and mammalian cells using alfalfa mosaic virus.

Venkatachalan SP, Bushman JD, Mercado JL, Sancar F, Christopherson KR, Boileau AJ.

Pflugers Arch. 2007 Apr;454(1):155-63. Epub 2006 Dec 5.

5.

Micromechanical measurement of membrane receptor binding for label-free drug discovery.

Zhang Y, Venkatachalan SP, Xu H, Xu X, Joshi P, Ji HF, Schulte M.

Biosens Bioelectron. 2004 Jun 15;19(11):1473-8.

PMID:
15093219
6.

Identification of critical residues in loop E in the 5-HT3ASR binding site.

Venkataraman P, Venkatachalan SP, Joshi PR, Muthalagi M, Schulte MK.

BMC Biochem. 2002 Jun 13;3:15. Epub 2002 Jun 13.

7.

Functional group interactions of a 5-HT3R antagonist.

Venkataraman P, Joshi P, Venkatachalan SP, Muthalagi M, Parihar HS, Kirschbaum KS, Schulte MK.

BMC Biochem. 2002 Jun 13;3:16. Epub 2002 Jun 13.

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