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ISL1 Is Necessary for Maximal Thyrotrope Response to Hypothyroidism.

Castinetti F, Brinkmeier ML, Mortensen AH, Vella KR, Gergics P, Brue T, Hollenberg AN, Gan L, Camper SA.

Mol Endocrinol. 2015 Oct;29(10):1510-21. doi: 10.1210/me.2015-1192. Epub 2015 Aug 21.


Age-Related Hearing Loss and Degeneration of Cochlear Hair Cells in Mice Lacking Thyroid Hormone Receptor β1.

Ng L, Cordas E, Wu X, Vella KR, Hollenberg AN, Forrest D.

Endocrinology. 2015 Oct;156(10):3853-65. doi: 10.1210/en.2015-1468. Epub 2015 Aug 4.


Impaired sinoatrial node function and increased susceptibility to atrial fibrillation in mice lacking natriuretic peptide receptor C.

Egom EE, Vella K, Hua R, Jansen HJ, Moghtadaei M, Polina I, Bogachev O, Hurnik R, Mackasey M, Rafferty S, Ray G, Rose RA.

J Physiol. 2015 Mar 1;593(5):1127-46. doi: 10.1113/jphysiol.2014.283135. Epub 2015 Jan 12.


The selective loss of the type 2 iodothyronine deiodinase in mouse thyrotrophs increases basal TSH but blunts the thyrotropin response to hypothyroidism.

Luongo C, Martin C, Vella K, Marsili A, Ambrosio R, Dentice M, Harney JW, Salvatore D, Zavacki AM, Larsen PR.

Endocrinology. 2015 Feb;156(2):745-54. doi: 10.1210/en.2014-1698. Epub 2014 Dec 2.


Mice with hepatocyte-specific deficiency of type 3 deiodinase have intact liver regeneration and accelerated recovery from nonthyroidal illness after toxin-induced hepatonecrosis.

Castroneves LA, Jugo RH, Maynard MA, Lee JS, Wassner AJ, Dorfman D, Bronson RT, Ukomadu C, Agoston AT, Ding L, Luongo C, Guo C, Song H, Demchev V, Lee NY, Feldman HA, Vella KR, Peake RW, Hartigan C, Kellogg MD, Desai A, Salvatore D, Dentice M, Huang SA.

Endocrinology. 2014 Oct;155(10):4061-8. doi: 10.1210/en.2013-2028. Epub 2014 Jul 8.


Comparison of assessments of fitness to drive for people with dementia.

Vella K, Lincoln NB.

Neuropsychol Rehabil. 2014;24(5):770-83. doi: 10.1080/09602011.2014.903197. Epub 2014 May 6.


Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors.

Vella KR, Ramadoss P, Costa-E-Sousa RH, Astapova I, Ye FD, Holtz KA, Harris JC, Hollenberg AN.

Mol Cell Biol. 2014 May;34(9):1564-75. doi: 10.1128/MCB.00129-14. Epub 2014 Feb 18.


Family members CREB and CREM control thyrotropin-releasing hormone (TRH) expression in the hypothalamus.

Chiappini F, Ramadoss P, Vella KR, Cunha LL, Ye FD, Stuart RC, Nillni EA, Hollenberg AN.

Mol Cell Endocrinol. 2013 Jan 5;365(1):84-94. doi: 10.1016/j.mce.2012.09.006. Epub 2012 Sep 20.


Natriuretic peptides regulate heart rate and sinoatrial node function by activating multiple natriuretic peptide receptors.

Azer J, Hua R, Vella K, Rose RA.

J Mol Cell Cardiol. 2012 Nov;53(5):715-24. doi: 10.1016/j.yjmcc.2012.08.020. Epub 2012 Aug 30.


NPY and MC4R signaling regulate thyroid hormone levels during fasting through both central and peripheral pathways.

Vella KR, Ramadoss P, Lam FS, Harris JC, Ye FD, Same PD, O'Neill NF, Maratos-Flier E, Hollenberg AN.

Cell Metab. 2011 Dec 7;14(6):780-90. doi: 10.1016/j.cmet.2011.10.009. Epub 2011 Nov 17.


PITX2 AND PITX1 regulate thyrotroph function and response to hypothyroidism.

Castinetti F, Brinkmeier ML, Gordon DF, Vella KR, Kerr JM, Mortensen AH, Hollenberg A, Brue T, Ridgway EC, Camper SA.

Mol Endocrinol. 2011 Nov;25(11):1950-60. doi: 10.1210/me.2010-0388. Epub 2011 Sep 29.


The nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-thyroid axis.

Astapova I, Vella KR, Ramadoss P, Holtz KA, Rodwin BA, Liao XH, Weiss RE, Rosenberg MA, Rosenzweig A, Hollenberg AN.

Mol Endocrinol. 2011 Feb;25(2):212-24. doi: 10.1210/me.2010-0462. Epub 2011 Jan 14.


Regulation of thyrotropin-releasing hormone-expressing neurons in paraventricular nucleus of the hypothalamus by signals of adiposity.

Ghamari-Langroudi M, Vella KR, Srisai D, Sugrue ML, Hollenberg AN, Cone RD.

Mol Endocrinol. 2010 Dec;24(12):2366-81. doi: 10.1210/me.2010-0203. Epub 2010 Oct 13.


Deletion of Nhlh2 results in a defective torpor response and reduced Beta adrenergic receptor expression in adipose tissue.

Wankhade UD, Vella KR, Fox DL, Good DJ.

PLoS One. 2010 Aug 23;5(8):e12324. doi: 10.1371/journal.pone.0012324.


The thyrotropin-releasing hormone gene is regulated by thyroid hormone at the level of transcription in vivo.

Sugrue ML, Vella KR, Morales C, Lopez ME, Hollenberg AN.

Endocrinology. 2010 Feb;151(2):793-801. doi: 10.1210/en.2009-0976. Epub 2009 Dec 23.


A prospective study of cognitive tests to predict performance on a standardised road test in people with dementia.

Lincoln NB, Taylor JL, Vella K, Bouman WP, Radford KA.

Int J Geriatr Psychiatry. 2010 May;25(5):489-96. doi: 10.1002/gps.2367.


The ups and downs of thyrotropin-releasing hormone.

Vella KR, Hollenberg AN.

Endocrinology. 2009 May;150(5):2021-3. doi: 10.1210/en.2009-0261. No abstract available.


Expression of the hypothalamic transcription factor Nhlh2 is dependent on energy availability.

Vella KR, Burnside AS, Brennan KM, Good DJ.

J Neuroendocrinol. 2007 Jul;19(7):499-510.


Energy balance pathways converging on the Nhlh2 transcription factor.

Fox DL, Vella KR, Good DJ.

Front Biosci. 2007 May 1;12:3983-93. Review.


Genetic analysis of NHLH2 and its putative role in bovine body weight control.

Brennan KM, Vella KR, Good DJ.

Anim Genet. 2006 Aug;37 Suppl 1:24-7.

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