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Results: 1 to 20 of 55

1.

Structural analysis and mutant growth properties reveal distinctive enzymatic and cellular roles for the three major L-alanine transaminases of Escherichia coli.

Peña-Soler E, Fernandez FJ, López-Estepa M, Garces F, Richardson AJ, Quintana JF, Rudd KE, Coll M, Vega MC.

PLoS One. 2014 Jul 11;9(7):e102139. doi: 10.1371/journal.pone.0102139. eCollection 2014.

PMID:
25014014
[PubMed - in process]
Free PMC Article
2.

Sex differences in LXR expression in normal offspring and in rats born to diabetic dams.

Kruse MS, Vega MC, Rey M, Coirini H.

J Endocrinol. 2014 Jul;222(1):53-60. doi: 10.1530/JOE-14-0054. Epub 2014 May 13.

PMID:
24824431
[PubMed - indexed for MEDLINE]
3.

Antiprotozoan lead discovery by aligning dry and wet screening: prediction, synthesis, and biological assay of novel quinoxalinones.

Martins Alho MA, Marrero-Ponce Y, Barigye SJ, Meneses-Marcel A, Machado Tugores Y, Montero-Torres A, Gómez-Barrio A, Nogal JJ, García-Sánchez RN, Vega MC, Rolón M, Martínez-Fernández AR, Escario JA, Pérez-Giménez F, Garcia-Domenech R, Rivera N, Mondragón R, Mondragón M, Ibarra-Velarde F, Lopez-Arencibia A, Martín-Navarro C, Lorenzo-Morales J, Cabrera-Serra MG, Piñero J, Tytgat J, Chicharro R, Arán VJ.

Bioorg Med Chem. 2014 Mar 1;22(5):1568-85. doi: 10.1016/j.bmc.2014.01.036. Epub 2014 Jan 31.

PMID:
24513185
[PubMed - indexed for MEDLINE]
4.

A case of Creutzfeldt-Jakob disease following cataract surgery: sporadic versus iatrogenic cause.

Gnanajothy R, Umashanker D, Vega MC, Wu BJ.

Conn Med. 2013 Jun-Jul;77(6):335-7.

PMID:
23923250
[PubMed - indexed for MEDLINE]
5.

Crystal structure, SAXS and kinetic mechanism of hyperthermophilic ADP-dependent glucokinase from Thermococcus litoralis reveal a conserved mechanism for catalysis.

Rivas-Pardo JA, Herrera-Morande A, Castro-Fernandez V, Fernandez FJ, Vega MC, Guixé V.

PLoS One. 2013 Jun 20;8(6):e66687. doi: 10.1371/journal.pone.0066687. Print 2013.

PMID:
23818958
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Technologies to keep an eye on: alternative hosts for protein production in structural biology.

Fernández FJ, Vega MC.

Curr Opin Struct Biol. 2013 Jun;23(3):365-73. doi: 10.1016/j.sbi.2013.02.002. Epub 2013 Mar 5. Review.

PMID:
23481468
[PubMed - indexed for MEDLINE]
7.

Catalysis uncoupling in a glutamine amidotransferase bienzyme by unblocking the glutaminase active site.

List F, Vega MC, Razeto A, Häger MC, Sterner R, Wilmanns M.

Chem Biol. 2012 Dec 21;19(12):1589-99. doi: 10.1016/j.chembiol.2012.10.012.

PMID:
23261602
[PubMed - indexed for MEDLINE]
Free Article
8.

Characterization of Arabidopsis FPS isozymes and FPS gene expression analysis provide insight into the biosynthesis of isoprenoid precursors in seeds.

Keim V, Manzano D, Fernández FJ, Closa M, Andrade P, Caudepón D, Bortolotti C, Vega MC, Arró M, Ferrer A.

PLoS One. 2012;7(11):e49109. doi: 10.1371/journal.pone.0049109. Epub 2012 Nov 7.

PMID:
23145086
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1,2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug.

Vega MC, Rolón M, Montero-Torres A, Fonseca-Berzal C, Escario JA, Gómez-Barrio A, Gálvez J, Marrero-Ponce Y, Arán VJ.

Eur J Med Chem. 2012 Dec;58:214-27. doi: 10.1016/j.ejmech.2012.10.009. Epub 2012 Oct 16.

PMID:
23124218
[PubMed - indexed for MEDLINE]
10.

Alterations of LXRα and LXRβ expression in the hypothalamus of glucose-intolerant rats.

Kruse MS, Rey M, Vega MC, Coirini H.

J Endocrinol. 2012 Oct;215(1):51-8. doi: 10.1530/JOE-12-0088. Epub 2012 Jul 25.

PMID:
22836489
[PubMed - indexed for MEDLINE]
Free Article
11.

Secretion of the housekeeping protein glyceraldehyde-3-phosphate dehydrogenase by the LEE-encoded type III secretion system in enteropathogenic Escherichia coli.

Aguilera L, Ferreira E, Giménez R, Fernández FJ, Taulés M, Aguilar J, Vega MC, Badia J, Baldomà L.

Int J Biochem Cell Biol. 2012 Jun;44(6):955-62. doi: 10.1016/j.biocel.2012.03.002. Epub 2012 Mar 12.

PMID:
22433988
[PubMed - indexed for MEDLINE]
12.

Down regulation of the proliferation and apoptotic pathways in the embryonic brain of diabetic rats.

Kruse MS, Barutta J, Vega MC, Coirini H.

Cell Mol Neurobiol. 2012 Aug;32(6):1031-7. doi: 10.1007/s10571-012-9820-8. Epub 2012 Mar 13.

PMID:
22410672
[PubMed - indexed for MEDLINE]
13.

Identification in silico and in vitro of novel trypanosomicidal drug-like compounds.

Castillo-Garit JA, Del Toro-Cortés O, Kouznetsov VV, Puentes CO, Romero Bohórquez AR, Vega MC, Rolón M, Escario JA, Gómez-Barrio A, Marrero-Ponce Y, Torrens F, Abad C.

Chem Biol Drug Des. 2012 Jul;80(1):38-45. doi: 10.1111/j.1747-0285.2012.01378.x. Epub 2012 Apr 27.

PMID:
22405194
[PubMed - indexed for MEDLINE]
14.

Structure and mechanism of a cysteine sulfinate desulfinase engineered on the aspartate aminotransferase scaffold.

Fernandez FJ, de Vries D, Peña-Soler E, Coll M, Christen P, Gehring H, Vega MC.

Biochim Biophys Acta. 2012 Feb;1824(2):339-49. doi: 10.1016/j.bbapap.2011.10.016. Epub 2011 Nov 23.

PMID:
22138634
[PubMed - indexed for MEDLINE]
15.

The UlaG protein family defines novel structural and functional motifs grafted on an ancient RNase fold.

Fernandez FJ, Garces F, López-Estepa M, Aguilar J, Baldomà L, Coll M, Badia J, Vega MC.

BMC Evol Biol. 2011 Sep 26;11:273. doi: 10.1186/1471-2148-11-273.

PMID:
21943130
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Structural features of peroxisomal catalase from the yeast Hansenula polymorpha.

Peña-Soler E, Vega MC, Wilmanns M, Williams C.

Acta Crystallogr D Biol Crystallogr. 2011 Aug;67(Pt 8):690-8. doi: 10.1107/S0907444911022463. Epub 2011 Jul 12.

PMID:
21795810
[PubMed - indexed for MEDLINE]
17.

Unique structure of iC3b resolved at a resolution of 24 Å by 3D-electron microscopy.

Alcorlo M, Martínez-Barricarte R, Fernández FJ, Rodríguez-Gallego C, Round A, Vega MC, Harris CL, de Cordoba SR, Llorca O.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13236-40. doi: 10.1073/pnas.1106746108. Epub 2011 Jul 25. Erratum in: Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16481.

PMID:
21788512
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Community participation in Chagas disease vector surveillance: systematic review.

Abad-Franch F, Vega MC, Rolón MS, Santos WS, Rojas de Arias A.

PLoS Negl Trop Dis. 2011 Jun;5(6):e1207. doi: 10.1371/journal.pntd.0001207. Epub 2011 Jun 21. Review.

PMID:
21713022
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Ligand-based discovery of novel trypanosomicidal drug-like compounds: in silico identification and experimental support.

Castillo-Garit JA, Vega MC, Rolón M, Marrero-Ponce Y, Gómez-Barrio A, Escario JA, Bello AA, Montero A, Torrens F, Pérez-Giménez F, Arán VJ, Abad C.

Eur J Med Chem. 2011 Aug;46(8):3324-30. doi: 10.1016/j.ejmech.2011.04.057. Epub 2011 May 5.

PMID:
21605926
[PubMed - indexed for MEDLINE]
20.

First report of colonies of sylvatic Triatoma infestans (Hemiptera: Reduviidae) in the Paraguayan Chaco, using a trained dog.

Rolón M, Vega MC, Román F, Gómez A, Rojas de Arias A.

PLoS Negl Trop Dis. 2011 May 3;5(5):e1026. doi: 10.1371/journal.pntd.0001026.

PMID:
21572522
[PubMed - indexed for MEDLINE]
Free PMC Article
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