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Hypoxia, mitochondrial dysfunction and synovial invasiveness in rheumatoid arthritis.

Fearon U, Canavan M, Biniecka M, Veale DJ.

Nat Rev Rheumatol. 2016 May 26. doi: 10.1038/nrrheum.2016.69. [Epub ahead of print] Review.


Ustekinumab for the treatment of refractory giant cell arteritis.

Conway R, O'Neill L, O'Flynn E, Gallagher P, McCarthy GM, Murphy CC, Veale DJ, Fearon U, Molloy ES.

Ann Rheum Dis. 2016 May 3. pii: annrheumdis-2016-209351. doi: 10.1136/annrheumdis-2016-209351. [Epub ahead of print] No abstract available.


Fatigue in psoriatic arthritis - a cross-sectional study of 246 patients from 13 countries.

Gudu T, Etcheto A, de Wit M, Heiberg T, Maccarone M, Balanescu A, Balint PV, Niedermayer DS, Cañete JD, Helliwell P, Kalyoncu U, Kiltz U, Otsa K, Veale DJ, de Vlam K, Scrivo R, Stamm T, Kvien TK, Gossec L.

Joint Bone Spine. 2016 Apr 4. pii: S1297-319X(16)00030-0. doi: 10.1016/j.jbspin.2015.07.017. [Epub ahead of print]


Dysregulated bioenergetics: a key regulator of joint inflammation.

Biniecka M, Canavan M, McGarry T, Gao W, McCormick J, Cregan S, Gallagher L, Smith T, Phelan JJ, Ryan J, O'Sullivan J, Ng CT, Veale DJ, Fearon U.

Ann Rheum Dis. 2016 Mar 24. pii: annrheumdis-2015-208476. doi: 10.1136/annrheumdis-2015-208476. [Epub ahead of print]


Patient global assessment in psoriatic arthritis - what does it mean? An analysis of 223 patients from the Psoriatic arthritis impact of disease (PsAID) study.

Tälli S, Etcheto A, Fautrel B, Balanescu A, Braun J, Cañete JD, de Vlam K, de Wit M, Heiberg T, Helliwell P, Kalyoncu U, Kiltz U, Maccarone M, Niedermayer D, Otsa K, Scrivo R, Smolen JS, Stamm T, Veale DJ, Kvien TK, Gossec L.

Joint Bone Spine. 2016 May;83(3):335-40. doi: 10.1016/j.jbspin.2015.06.018. Epub 2015 Dec 8.


European League Against Rheumatism (EULAR) recommendations for the management of psoriatic arthritis with pharmacological therapies: 2015 update.

Gossec L, Smolen JS, Ramiro S, de Wit M, Cutolo M, Dougados M, Emery P, Landewé R, Oliver S, Aletaha D, Betteridge N, Braun J, Burmester G, Cañete JD, Damjanov N, FitzGerald O, Haglund E, Helliwell P, Kvien TK, Lories R, Luger T, Maccarone M, Marzo-Ortega H, McGonagle D, McInnes IB, Olivieri I, Pavelka K, Schett G, Sieper J, van den Bosch F, Veale DJ, Wollenhaupt J, Zink A, van der Heijde D.

Ann Rheum Dis. 2016 Mar;75(3):499-510. doi: 10.1136/annrheumdis-2015-208337. Epub 2015 Dec 7.


What makes psoriatic and rheumatoid arthritis so different?

Veale DJ, Fearon U.

RMD Open. 2015 Apr 28;1(1):e000025. doi: 10.1136/rmdopen-2014-000025. eCollection 2015. Review.


Factors that influence fatigue status in patients with severe rheumatoid arthritis (RA) and good disease outcome following 6 months of TNF inhibitor therapy: a comparative analysis.

Minnock P, Veale DJ, Bresnihan B, FitzGerald O, McKee G.

Clin Rheumatol. 2015 Nov;34(11):1857-65. doi: 10.1007/s10067-015-3088-6. Epub 2015 Oct 9.


Tofacitinib regulates synovial inflammation in psoriatic arthritis, inhibiting STAT activation and induction of negative feedback inhibitors.

Gao W, McGarry T, Orr C, McCormick J, Veale DJ, Fearon U.

Ann Rheum Dis. 2016 Jan;75(1):311-5. doi: 10.1136/annrheumdis-2014-207201. Epub 2015 Sep 9.


Acute serum amyloid A is an endogenous TLR2 ligand that mediates inflammatory and angiogenic mechanisms.

Connolly M, Rooney PR, McGarry T, Maratha AX, McCormick J, Miggin SM, Veale DJ, Fearon U.

Ann Rheum Dis. 2015 Aug 19. pii: annrheumdis-2015-207655. doi: 10.1136/annrheumdis-2015-207655. [Epub ahead of print]


Key Challenges in Rheumatic and Musculoskeletal Disease Translational Research.

Fearon U, Veale DJ.

EBioMedicine. 2014 Nov 18;1(2-3):95-6. doi: 10.1016/j.ebiom.2014.11.011. eCollection 2014 Dec. No abstract available.


A clinically based protein discovery strategy to identify potential biomarkers of response to anti-TNF-α treatment of psoriatic arthritis.

Collins ES, Butt AQ, Gibson DS, Dunn MJ, Fearon U, van Kuijk AW, Gerlag DM, Pontifex E, Veale DJ, Tak PP, FitzGerald O, Pennington SR.

Proteomics Clin Appl. 2015 Jun 24. doi: 10.1002/prca.201500051. [Epub ahead of print]


Polyfunctional, Pathogenic CD161+ Th17 Lineage Cells Are Resistant to Regulatory T Cell-Mediated Suppression in the Context of Autoimmunity.

Basdeo SA, Moran B, Cluxton D, Canavan M, McCormick J, Connolly M, Orr C, Mills KH, Veale DJ, Fearon U, Fletcher JM.

J Immunol. 2015 Jul 15;195(2):528-40. doi: 10.4049/jimmunol.1402990. Epub 2015 Jun 10.


Toll-like receptor 2 (TLR2) induces migration and invasive mechanisms in rheumatoid arthritis.

McGarry T, Veale DJ, Gao W, Orr C, Fearon U, Connolly M.

Arthritis Res Ther. 2015 Jun 9;17:153. doi: 10.1186/s13075-015-0664-8.


Evaluation of Minimally Invasive, Ultrasound-guided Synovial Biopsy Techniques by the OMERACT Filter--Determining Validation Requirements.

Humby F, Kelly S, Bugatti S, Manzo A, Filer A, Mahto A, Fonseca JE, Lauwerys B, D'Agostino MA, Naredo E, Lories R, Montecucco C, Tak PP, Fitzgerald O, Smith MD, Veale DJ, Choy EH, Strand V, Pitzalis C.

J Rheumatol. 2016 Jan;43(1):208-13. doi: 10.3899/jrheum.141199. Epub 2015 Jun 1.


Regulation of Inflammation and Angiogenesis in Giant Cell Arteritis by Acute-Phase Serum Amyloid A.

O'Neill L, Rooney P, Molloy D, Connolly M, McCormick J, McCarthy G, Veale DJ, Murphy CC, Fearon U, Molloy E.

Arthritis Rheumatol. 2015 Sep;67(9):2447-56. doi: 10.1002/art.39217.


Biomarkers for rheumatoid and psoriatic arthritis.

Verheul MK, Fearon U, Trouw LA, Veale DJ.

Clin Immunol. 2015 Nov;161(1):2-10. doi: 10.1016/j.clim.2015.04.005. Epub 2015 Apr 28. Review.


Redox-mediated angiogenesis in the hypoxic joint of inflammatory arthritis.

Biniecka M, Connolly M, Gao W, Ng CT, Balogh E, Gogarty M, Santos L, Murphy E, Brayden D, Veale DJ, Fearon U.

Arthritis Rheumatol. 2014 Dec;66(12):3300-10. doi: 10.1002/art.38822.


How much is fatigue explained by standard clinical characteristics of disease activity in patients with inflammatory arthritis? A longitudinal study.

Minnock P, McKee G, Bresnihan B, FitzGerald O, Veale DJ.

Arthritis Care Res (Hoboken). 2014 Nov;66(11):1597-603. doi: 10.1002/acr.22387.


Is there a need for new agents with novel mechanisms of action in psoriatic arthritis?

Orr C, Veale DJ.

Ann Rheum Dis. 2014 Jun;73(6):951-3. doi: 10.1136/annrheumdis-2013-204934. No abstract available.

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