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Items: 1 to 20 of 76


Update of the human and mouse Fanconi anemia genes.

Dong H, Nebert DW, Bruford EA, Thompson DC, Joenje H, Vasiliou V.

Hum Genomics. 2015 Nov 24;9(1):32. doi: 10.1186/s40246-015-0054-y.


ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/β-Catenin, Notch and PI3K/Akt Signaling Pathways.

Singh S, Arcaroli J, Chen Y, Thompson DC, Messersmith W, Jimeno A, Vasiliou V.

PLoS One. 2015 May 7;10(5):e0121648. doi: 10.1371/journal.pone.0121648. eCollection 2015.


Transgenic mouse models for alcohol metabolism, toxicity, and cancer.

Heit C, Dong H, Chen Y, Shah YM, Thompson DC, Vasiliou V.

Adv Exp Med Biol. 2015;815:375-87. doi: 10.1007/978-3-319-09614-8_22.


Acetaldehyde and retinaldehyde-metabolizing enzymes in colon and pancreatic cancers.

Singh S, Arcaroli J, Thompson DC, Messersmith W, Vasiliou V.

Adv Exp Med Biol. 2015;815:281-94. doi: 10.1007/978-3-319-09614-8_16. Review.


Improved drug therapy: triangulating phenomics with genomics and metabolomics.

Monte AA, Brocker C, Nebert DW, Gonzalez FJ, Thompson DC, Vasiliou V.

Hum Genomics. 2014 Sep 1;8:16. doi: 10.1186/s40246-014-0016-9. Review.


The effect of CYP2D6 drug-drug interactions on hydrocodone effectiveness.

Monte AA, Heard KJ, Campbell J, Hamamura D, Weinshilboum RM, Vasiliou V.

Acad Emerg Med. 2014 Aug;21(8):879-85. doi: 10.1111/acem.12431. Epub 2014 Aug 24.


aldh7a1 regulates eye and limb development in zebrafish.

Babcock HE, Dutta S, Alur RP, Brocker C, Vasiliou V, Vitale S, Abu-Asab M, Brooks BP.

PLoS One. 2014 Jul 8;9(7):e101782. doi: 10.1371/journal.pone.0101782. eCollection 2014.


Aldehyde dehydrogenase 2 deficiency ameliorates alcoholic fatty liver but worsens liver inflammation and fibrosis in mice.

Kwon HJ, Won YS, Park O, Chang B, Duryee MJ, Thiele GE, Matsumoto A, Singh S, Abdelmegeed MA, Song BJ, Kawamoto T, Vasiliou V, Thiele GM, Gao B.

Hepatology. 2014 Jul;60(1):146-57. doi: 10.1002/hep.27036. Epub 2014 May 28.


Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity.

Jang JH, Bruse S, Liu Y, Duffy V, Zhang C, Oyamada N, Randell S, Matsumoto A, Thompson DC, Lin Y, Vasiliou V, Tesfaigzi Y, Nyunoya T.

Free Radic Biol Med. 2014 Mar;68:80-6. doi: 10.1016/j.freeradbiomed.2013.11.028. Epub 2013 Dec 4.


Update of the human and mouse SERPIN gene superfamily.

Heit C, Jackson BC, McAndrews M, Wright MW, Thompson DC, Silverman GA, Nebert DW, Vasiliou V.

Hum Genomics. 2013 Oct 30;7:22. doi: 10.1186/1479-7364-7-22. Review.


Glutathione defense mechanism in liver injury: insights from animal models.

Chen Y, Dong H, Thompson DC, Shertzer HG, Nebert DW, Vasiliou V.

Food Chem Toxicol. 2013 Oct;60:38-44. doi: 10.1016/j.fct.2013.07.008. Epub 2013 Jul 12. Review.


Mechanisms for PDGF, a serum cytokine, stimulating loss of corneal keratocyte crystallins.

LaGier AJ, Gordon GM, Katzman LR, Vasiliou V, Fini ME.

Cornea. 2013 Sep;32(9):1269-75. doi: 10.1097/ICO.0b013e318296e0b9.


Genetic tests obtainable through pharmacies: the good, the bad, and the ugly.

Patrinos GP, Baker DJ, Al-Mulla F, Vasiliou V, Cooper DN.

Hum Genomics. 2013 Jul 8;7:17. doi: 10.1186/1479-7364-7-17.


Mitochondrial targeting of mouse NQO1 and CYP1B1 proteins.

Dong H, Shertzer HG, Genter MB, Gonzalez FJ, Vasiliou V, Jefcoate C, Nebert DW.

Biochem Biophys Res Commun. 2013 Jun 14;435(4):727-32. doi: 10.1016/j.bbrc.2013.05.051. Epub 2013 May 18.


The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system.

Heit C, Dong H, Chen Y, Thompson DC, Deitrich RA, Vasiliou VK.

Subcell Biochem. 2013;67:235-47. doi: 10.1007/978-94-007-5881-0_8. Review.


ALDH16A1 is a novel non-catalytic enzyme that may be involved in the etiology of gout via protein-protein interactions with HPRT1.

Vasiliou V, Sandoval M, Backos DS, Jackson BC, Chen Y, Reigan P, Lanaspa MA, Johnson RJ, Koppaka V, Thompson DC.

Chem Biol Interact. 2013 Feb 25;202(1-3):22-31. doi: 10.1016/j.cbi.2012.12.018. Epub 2013 Jan 21.


Omics Screening for Pharmaceutical Efficacy and Safety in Clinical Practice.

Monte AA, Vasiliou V, Heard KJ.

J Pharmacogenomics Pharmacoproteomics. 2012 Mar 16;S5. pii: 001.


Comparative genomics, molecular evolution and computational modeling of ALDH1B1 and ALDH2.

Jackson BC, Holmes RS, Backos DS, Reigan P, Thompson DC, Vasiliou V.

Chem Biol Interact. 2013 Feb 25;202(1-3):11-21. doi: 10.1016/j.cbi.2012.11.022. Epub 2012 Dec 13.


A new home for Human Genomics.

Vasiliou V, Nebert DW.

Hum Genomics. 2012 Jul 5;6:1. doi: 10.1186/1479-7364-6-1. No abstract available.


A new era in the discovery of de novo mutations underlying human genetic disease.

Ku CS, Vasiliou V, Cooper DN.

Hum Genomics. 2012 Dec 12;6:27. doi: 10.1186/1479-7364-6-27. No abstract available.

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