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Results: 1 to 20 of 161

1.

Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1).

Yang SM, Yasgar A, Miller B, Lal-Nag M, Brimacombe K, Hu X, Sun H, Wang A, Xu X, Nguyen K, Oppermann U, Ferrer M, Vasiliou V, Simeonov A, Jadhav A, Maloney DJ.

J Med Chem. 2015 Jul 24. [Epub ahead of print]

PMID:
26207746
2.

ALDH1B1 links alcohol consumption and diabetes.

Singh S, Chen Y, Matsumoto A, Orlicky DJ, Dong H, Thompson DC, Vasiliou V.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):768-73. doi: 10.1016/j.bbrc.2015.06.011. Epub 2015 Jun 15.

PMID:
26086111
3.

ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/β-Catenin, Notch and PI3K/Akt Signaling Pathways.

Singh S, Arcaroli J, Chen Y, Thompson DC, Messersmith W, Jimeno A, Vasiliou V.

PLoS One. 2015 May 7;10(5):e0121648. doi: 10.1371/journal.pone.0121648. eCollection 2015.

4.

Accuracy of Electronic Medical Record Medication Reconciliation in Emergency Department Patients.

Monte AA, Anderson P, Hoppe JA, Weinshilboum RM, Vasiliou V, Heard KJ.

J Emerg Med. 2015 Jul;49(1):78-84. doi: 10.1016/j.jemermed.2014.12.052. Epub 2015 Mar 19.

PMID:
25797942
5.

Transgenic mouse models for alcohol metabolism, toxicity, and cancer.

Heit C, Dong H, Chen Y, Shah YM, Thompson DC, Vasiliou V.

Adv Exp Med Biol. 2015;815:375-87. doi: 10.1007/978-3-319-09614-8_22.

6.

The effects of alcohol and aldehyde dehydrogenases on disorders of hematopoiesis.

Smith C, Gasparetto M, Jordan C, Pollyea DA, Vasiliou V.

Adv Exp Med Biol. 2015;815:349-59. doi: 10.1007/978-3-319-09614-8_20. Review.

PMID:
25427917
7.

Acetaldehyde and retinaldehyde-metabolizing enzymes in colon and pancreatic cancers.

Singh S, Arcaroli J, Thompson DC, Messersmith W, Vasiliou V.

Adv Exp Med Biol. 2015;815:281-94. doi: 10.1007/978-3-319-09614-8_16. Review.

8.

Human ALDH1B1 polymorphisms may affect the metabolism of acetaldehyde and all-trans retinaldehyde--in vitro studies and computational modeling.

Jackson BC, Reigan P, Miller B, Thompson DC, Vasiliou V.

Pharm Res. 2015 May;32(5):1648-62. doi: 10.1007/s11095-014-1564-3. Epub 2014 Nov 21.

PMID:
25413692
9.

Improved drug therapy: triangulating phenomics with genomics and metabolomics.

Monte AA, Brocker C, Nebert DW, Gonzalez FJ, Thompson DC, Vasiliou V.

Hum Genomics. 2014 Sep 1;8:16. doi: 10.1186/s40246-014-0016-9.

10.

The effect of CYP2D6 drug-drug interactions on hydrocodone effectiveness.

Monte AA, Heard KJ, Campbell J, Hamamura D, Weinshilboum RM, Vasiliou V.

Acad Emerg Med. 2014 Aug;21(8):879-85. doi: 10.1111/acem.12431. Epub 2014 Aug 24.

PMID:
25156930
11.

The accuracy of self-reported drug ingestion histories in emergency department patients.

Monte AA, Heard KJ, Hoppe JA, Vasiliou V, Gonzalez FJ.

J Clin Pharmacol. 2015 Jan;55(1):33-8. doi: 10.1002/jcph.368. Epub 2014 Jul 28.

PMID:
25052325
12.

aldh7a1 regulates eye and limb development in zebrafish.

Babcock HE, Dutta S, Alur RP, Brocker C, Vasiliou V, Vitale S, Abu-Asab M, Brooks BP.

PLoS One. 2014 Jul 8;9(7):e101782. doi: 10.1371/journal.pone.0101782. eCollection 2014.

13.

Ethanol reduces lifespan, body weight, and serum alanine aminotransferase level of aldehyde dehydrogenase 2 knockout mouse.

Matsumoto A, Vasiliou V, Kawamoto T, Tanaka K, Ichiba M.

Alcohol Clin Exp Res. 2014 Jul;38(7):1883-93. doi: 10.1111/acer.12462. Epub 2014 Jun 13.

PMID:
24930774
14.

Aldehyde dehydrogenases in acute myeloid leukemia.

Smith C, Gasparetto M, Humphries K, Pollyea DA, Vasiliou V, Jordan CT.

Ann N Y Acad Sci. 2014 Mar;1310:58-68. doi: 10.1111/nyas.12414. Review.

PMID:
24641679
15.

Aldehyde dehydrogenase 2 deficiency ameliorates alcoholic fatty liver but worsens liver inflammation and fibrosis in mice.

Kwon HJ, Won YS, Park O, Chang B, Duryee MJ, Thiele GE, Matsumoto A, Singh S, Abdelmegeed MA, Song BJ, Kawamoto T, Vasiliou V, Thiele GM, Gao B.

Hepatology. 2014 Jul;60(1):146-57. doi: 10.1002/hep.27036. Epub 2014 May 28.

16.

Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity.

Jang JH, Bruse S, Liu Y, Duffy V, Zhang C, Oyamada N, Randell S, Matsumoto A, Thompson DC, Lin Y, Vasiliou V, Tesfaigzi Y, Nyunoya T.

Free Radic Biol Med. 2014 Mar;68:80-6. doi: 10.1016/j.freeradbiomed.2013.11.028. Epub 2013 Dec 4.

17.

Update of the human and mouse SERPIN gene superfamily.

Heit C, Jackson BC, McAndrews M, Wright MW, Thompson DC, Silverman GA, Nebert DW, Vasiliou V.

Hum Genomics. 2013 Oct 30;7:22. doi: 10.1186/1479-7364-7-22. Review.

18.

Glutathione defense mechanism in liver injury: insights from animal models.

Chen Y, Dong H, Thompson DC, Shertzer HG, Nebert DW, Vasiliou V.

Food Chem Toxicol. 2013 Oct;60:38-44. doi: 10.1016/j.fct.2013.07.008. Epub 2013 Jul 12. Review.

19.

Mechanisms for PDGF, a serum cytokine, stimulating loss of corneal keratocyte crystallins.

LaGier AJ, Gordon GM, Katzman LR, Vasiliou V, Fini ME.

Cornea. 2013 Sep;32(9):1269-75. doi: 10.1097/ICO.0b013e318296e0b9.

20.

Genetic tests obtainable through pharmacies: the good, the bad, and the ugly.

Patrinos GP, Baker DJ, Al-Mulla F, Vasiliou V, Cooper DN.

Hum Genomics. 2013 Jul 8;7:17. doi: 10.1186/1479-7364-7-17.

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