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Items: 1 to 20 of 214

1.

A tale of two cities: A tribute to Aziz Sancar's Nobel Prize in Chemistry for his molecular characterization of NER.

Van Houten B.

DNA Repair (Amst). 2016 Jan;37:A3-A13. doi: 10.1016/j.dnarep.2015.12.002. No abstract available.

PMID:
26861185
2.

Mitochondrial DNA damage induced autophagy, cell death, and disease.

Van Houten B, Hunter SE, Meyer JN.

Front Biosci (Landmark Ed). 2016 Jan 1;21:42-54.

3.

Directly interrogating single quantum dot labelled UvrA2 molecules on DNA tightropes using an optically trapped nanoprobe.

Simons M, Pollard MR, Hughes CD, Ward AD, Van Houten B, Towrie M, Botchway SW, Parker AW, Kad NM.

Sci Rep. 2015 Dec 22;5:18486. doi: 10.1038/srep18486.

4.

Pulmonary Arterial Hypertension Is Associated with Oxidative Stress-induced Genome Instability.

Van Houten B.

Am J Respir Crit Care Med. 2015 Jul 15;192(2):129-30. doi: 10.1164/rccm.201505-0904ED. No abstract available.

PMID:
26177169
5.

Mitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cells.

Ma J, Lim C, Sacher JR, Van Houten B, Qian W, Wipf P.

Bioorg Med Chem Lett. 2015 Nov 1;25(21):4828-33. doi: 10.1016/j.bmcl.2015.06.073. Epub 2015 Jun 26.

PMID:
26159482
6.

The combination of thioxodihydroquinazolinones and platinum drugs reverses platinum resistance in tumor cells by inducing mitochondrial apoptosis independent of Bax and Bak.

Qian W, Salamoun J, Wang J, Roginskaya V, Van Houten B, Wipf P.

Bioorg Med Chem Lett. 2015 Feb 15;25(4):856-63. doi: 10.1016/j.bmcl.2014.12.072. Epub 2014 Dec 30.

7.

Kinetic gating mechanism of DNA damage recognition by Rad4/XPC.

Chen X, Velmurugu Y, Zheng G, Park B, Shim Y, Kim Y, Liu L, Van Houten B, He C, Ansari A, Min JH.

Nat Commun. 2015 Jan 6;6:5849. doi: 10.1038/ncomms6849.

8.

A novel strategy for targeted killing of tumor cells: Induction of multipolar acentrosomal mitotic spindles with a quinazolinone derivative mdivi-1.

Wang J, Li J, Santana-Santos L, Shuda M, Sobol RW, Van Houten B, Qian W.

Mol Oncol. 2015 Feb;9(2):488-502. doi: 10.1016/j.molonc.2014.10.002. Epub 2014 Oct 17.

9.

Mitochondrial division inhibitor 1 (mdivi-1) enhances death receptor-mediated apoptosis in human ovarian cancer cells.

Wang J, Hansen K, Edwards R, Van Houten B, Qian W.

Biochem Biophys Res Commun. 2015 Jan 2;456(1):7-12. doi: 10.1016/j.bbrc.2014.11.010. Epub 2014 Nov 13.

10.

TAp73 promotes cell survival upon genotoxic stress by inhibiting p53 activity.

Chen D, Ming L, Zou F, Peng Y, Van Houten B, Yu J, Zhang L.

Oncotarget. 2014 Sep 30;5(18):8107-22.

11.

ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion.

Fouquerel E, Goellner EM, Yu Z, Gagné JP, Barbi de Moura M, Feinstein T, Wheeler D, Redpath P, Li J, Romero G, Migaud M, Van Houten B, Poirier GG, Sobol RW.

Cell Rep. 2014 Sep 25;8(6):1819-31. doi: 10.1016/j.celrep.2014.08.036. Epub 2014 Sep 15.

12.

Overexpression of mitochondrial sirtuins alters glycolysis and mitochondrial function in HEK293 cells.

de Moura MB, Uppala R, Zhang Y, Van Houten B, Goetzman ES.

PLoS One. 2014 Aug 28;9(8):e106028. doi: 10.1371/journal.pone.0106028. eCollection 2014.

13.

Mitochondria, energetics, epigenetics, and cellular responses to stress.

Shaughnessy DT, McAllister K, Worth L, Haugen AC, Meyer JN, Domann FE, Van Houten B, Mostoslavsky R, Bultman SJ, Baccarelli AA, Begley TJ, Sobol RW, Hirschey MD, Ideker T, Santos JH, Copeland WC, Tice RR, Balshaw DM, Tyson FL.

Environ Health Perspect. 2014 Dec;122(12):1271-8. doi: 10.1289/ehp.1408418. Epub 2014 Aug 15. Review.

14.

Quantifying metabolic heterogeneity in head and neck tumors in real time: 2-DG uptake is highest in hypoxic tumor regions.

Nakajima EC, Laymon C, Oborski M, Hou W, Wang L, Grandis JR, Ferris RL, Mountz JM, Van Houten B.

PLoS One. 2014 Aug 15;9(8):e102452. doi: 10.1371/journal.pone.0102452. eCollection 2014.

15.

Single molecule approaches: watching DNA repair one molecule at a time. Preface.

Kad NM, Van Houten B.

DNA Repair (Amst). 2014 Aug;20:1. doi: 10.1016/j.dnarep.2014.06.007. No abstract available.

PMID:
25059729
16.

Mitochondrial DNA damage: molecular marker of vulnerable nigral neurons in Parkinson's disease.

Sanders LH, McCoy J, Hu X, Mastroberardino PG, Dickinson BC, Chang CJ, Chu CT, Van Houten B, Greenamyre JT.

Neurobiol Dis. 2014 Oct;70:214-23. doi: 10.1016/j.nbd.2014.06.014. Epub 2014 Jun 27.

17.

Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells.

Qian W, Wang J, Roginskaya V, McDermott LA, Edwards RP, Stolz DB, Llambi F, Green DR, Van Houten B.

Oncotarget. 2014 Jun 30;5(12):4180-94.

18.

High mobility group box 1 (HMGB1) phenotypic role revealed with stress.

Tang D, Kang R, Van Houten B, Zeh HJ, Billiar TR, Lotze MT.

Mol Med. 2014 Aug 19;20:359-62. doi: 10.2119/molmed.2014.00063.

19.
20.

Single molecule techniques in DNA repair: a primer.

Hughes CD, Simons M, Mackenzie CE, Van Houten B, Kad NM.

DNA Repair (Amst). 2014 Aug;20:2-13. doi: 10.1016/j.dnarep.2014.02.003. Epub 2014 May 10. Review.

PMID:
24819596
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