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Results: 1 to 20 of 69

1.

Advancing the 3Rs in regulatory toxicology - Carcinogenicity testing: Scope for harmonisation and advancing the 3Rs in regulated sectors of the European Union.

Annys E, Billington R, Clayton R, Bremm KD, Graziano M, McKelvie J, Ragan I, Schwarz M, van der Laan JW, Wood C, Öberg M, Wester P, Woodward KN.

Regul Toxicol Pharmacol. 2014 Jul;69(2):234-42. doi: 10.1016/j.yrtph.2014.04.009. Epub 2014 Apr 24.

PMID:
24768934
[PubMed - in process]
2.

Classifying the adverse mitogenic mode of action of insulin analogues using a novel mechanism-based genetically engineered human breast cancer cell panel.

ter Braak B, Siezen CL, Kannegieter N, Koedoot E, van de Water B, van der Laan JW.

Arch Toxicol. 2014 Apr;88(4):953-66. doi: 10.1007/s00204-014-1201-2. Epub 2014 Jan 25.

PMID:
24464500
[PubMed - in process]
3.

Approaches and considerations for the assessment of immunotoxicity for environmental chemicals: a workshop summary.

Boverhof DR, Ladics G, Luebke B, Botham J, Corsini E, Evans E, Germolec D, Holsapple M, Loveless SE, Lu H, van der Laan JW, White KL Jr, Yang Y.

Regul Toxicol Pharmacol. 2014 Feb;68(1):96-107. doi: 10.1016/j.yrtph.2013.11.012. Epub 2013 Nov 23.

PMID:
24280359
[PubMed - indexed for MEDLINE]
4.

The value of non-human primates in the development of monoclonal antibodies.

van Meer PJ, Kooijman M, van der Laan JW, Moors EH, Schellekens H.

Nat Biotechnol. 2013 Oct;31(10):882-3. doi: 10.1038/nbt.2709. No abstract available.

PMID:
24104750
[PubMed - indexed for MEDLINE]
5.

Challenges and approaches for the development of safer immunomodulatory biologics.

Sathish JG, Sethu S, Bielsky MC, de Haan L, French NS, Govindappa K, Green J, Griffiths CE, Holgate S, Jones D, Kimber I, Moggs J, Naisbitt DJ, Pirmohamed M, Reichmann G, Sims J, Subramanyam M, Todd MD, Van Der Laan JW, Weaver RJ, Park BK.

Nat Rev Drug Discov. 2013 Apr;12(4):306-24. doi: 10.1038/nrd3974. Review.

PMID:
23535934
[PubMed - indexed for MEDLINE]
6.

Response to 'Statins accelerate the onset of collagen type II-induced arthritis in mice'-authors' reply.

Vandebriel RJ, De Jong HJ, Gremmer ER, Klungel OH, Tervaert JW, Slob W, Van Der Laan JW, Van Loveren H.

Arthritis Res Ther. 2013 Mar 8;15(2):403. doi: 10.1186/ar4170. No abstract available.

PMID:
23472848
[PubMed - in process]
Free PMC Article
7.

Statins accelerate the onset of collagen type II-induced arthritis in mice.

Vandebriel RJ, De Jong HJ, Gremmer ER, Klungel OH, Tervaert JW, Slob W, Van Der Laan JW, Van Loveren H.

Arthritis Res Ther. 2012 Apr 26;14(2):R90. doi: 10.1186/ar3814.

PMID:
22537858
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Testing strategies for embryo-fetal toxicity of human pharmaceuticals. Animal models vs. in vitro approaches: a workshop report.

van der Laan JW, Chapin RE, Haenen B, Jacobs AC, Piersma A.

Regul Toxicol Pharmacol. 2012 Jun;63(1):115-23. doi: 10.1016/j.yrtph.2012.03.009. Epub 2012 Mar 16.

PMID:
22449444
[PubMed - indexed for MEDLINE]
9.

What it means to be global.

Roberts RA, Wallis R, Ren J, van der Laan JW, Sausen PJ, Slikker W Jr.

Toxicol Sci. 2012 May;127(1):313-4. doi: 10.1093/toxsci/kfs079. Epub 2012 Feb 14. No abstract available.

PMID:
22334561
[PubMed - indexed for MEDLINE]
Free Article
10.

Use of statins is associated with an increased risk of rheumatoid arthritis.

de Jong HJ, Klungel OH, van Dijk L, Vandebriel RJ, Leufkens HG, van der Laan JW, Cohen Tervaert JW, van Loveren H.

Ann Rheum Dis. 2012 May;71(5):648-54. doi: 10.1136/ard.2011.155622. Epub 2011 Oct 6.

PMID:
21979000
[PubMed - indexed for MEDLINE]
11.

New adjuvanted vaccines in pregnancy: what is known about their safety?

Herberts C, Melgert B, van der Laan JW, Faas M.

Expert Rev Vaccines. 2010 Dec;9(12):1411-22. doi: 10.1586/erv.10.133. Review.

PMID:
21105777
[PubMed - indexed for MEDLINE]
12.

Human and environmental health challenges for the next decade (2010–2020).

Bonnefoi MS, Belanger SE, Devlin DJ, Doerrer NG, Embry MR, Fukushima S, Harpur ES, Hines RN, Holsapple MP, Kim JH, MacDonald JS, O'Lone R, Pettit SD, Stevens JL, Takei AS, Tinkle SS, van der Laan JW.

Crit Rev Toxicol. 2010 Nov;40(10):893-911. doi: 10.3109/10408444.2010.506640. Review.

PMID:
20854192
[PubMed - indexed for MEDLINE]
13.

The RETHINK project--minipigs as models for the toxicity testing of new medicines and chemicals: an impact assessment.

Forster R, Bode G, Ellegaard L, van der Laan JW; Steering Group of the RETHINK Project.

J Pharmacol Toxicol Methods. 2010 Nov-Dec;62(3):158-9. doi: 10.1016/j.vascn.2010.05.003. Epub 2010 Jun 1.

PMID:
20685395
[PubMed - indexed for MEDLINE]
14.

The RETHINK project on minipigs in the toxicity testing of new medicines and chemicals: conclusions and recommendations.

Forster R, Bode G, Ellegaard L, van der Laan JW.

J Pharmacol Toxicol Methods. 2010 Nov-Dec;62(3):236-42. doi: 10.1016/j.vascn.2010.05.008. Epub 2010 May 31. Review.

PMID:
20685309
[PubMed - indexed for MEDLINE]
15.

Regulatory acceptability of the minipig in the development of pharmaceuticals, chemicals and other products.

van der Laan JW, Brightwell J, McAnulty P, Ratky J, Stark C; Steering Group of the RETHINK Project.

J Pharmacol Toxicol Methods. 2010 Nov-Dec;62(3):184-95. doi: 10.1016/j.vascn.2010.05.005. Epub 2010 Jun 16. Review.

PMID:
20601024
[PubMed - indexed for MEDLINE]
16.

In vitro cytokine release assays for predicting cytokine release syndrome: the current state-of-the-science. Report of a European Medicines Agency Workshop.

Vidal JM, Kawabata TT, Thorpe R, Silva-Lima B, Cederbrant K, Poole S, Mueller-Berghaus J, Pallardy M, Van der Laan JW.

Cytokine. 2010 Aug;51(2):213-5. doi: 10.1016/j.cyto.2010.04.008. Epub 2010 May 14. No abstract available.

PMID:
20471854
[PubMed - indexed for MEDLINE]
17.

An interspecies comparison of placental antibody transfer: new insights into developmental toxicity testing of monoclonal antibodies.

Pentsuk N, van der Laan JW.

Birth Defects Res B Dev Reprod Toxicol. 2009 Aug;86(4):328-44. doi: 10.1002/bdrb.20201. Review.

PMID:
19626656
[PubMed - indexed for MEDLINE]
18.

Development of the ICH guidelines for immunotoxicology evaluation of pharmaceuticals using a survey of industry practices.

Weaver JL, Tsutsui N, Hisada S, Vidal JM, Spanhaak S, Sawada J, Hastings KL, van der Laan JW, van Loveren H, Kawabata TT, Sims J, Durham SK, Fueki O, Matula TI, Kusunoki H, Ulrich P, Nakamura K.

J Immunotoxicol. 2005 Jul 1;2(3):171-80. doi: 10.1080/15476910500241339.

PMID:
18958670
[PubMed]
19.

Animal models in influenza vaccine testing.

van der Laan JW, Herberts C, Lambkin-Williams R, Boyers A, Mann AJ, Oxford J.

Expert Rev Vaccines. 2008 Aug;7(6):783-93. doi: 10.1586/14760584.7.6.783. Review.

PMID:
18665776
[PubMed - indexed for MEDLINE]
20.

[Use of SSRIs during pregnancy and possible consequences for the development of the child].

te Winkel AG, van Eijkeren MA, van der Laan JW.

Ned Tijdschr Geneeskd. 2008 Apr 19;152(16):970; author reply 970. Dutch. No abstract available.

PMID:
18561796
[PubMed - indexed for MEDLINE]

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