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Items: 20

1.

Upregulation of the Adhesin Gene EPA1 Mediated by PDR1 in Candida glabrata Leads to Enhanced Host Colonization.

Vale-Silva LA, Moeckli B, Torelli R, Posteraro B, Sanguinetti M, Sanglard D.

mSphere. 2016 Mar 2;1(2). pii: e00065-15. doi: 10.1128/mSphere.00065-15. eCollection 2016 Mar-Apr.

2.

Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction.

Nishikawa JL, Boeszoermenyi A, Vale-Silva LA, Torelli R, Posteraro B, Sohn YJ, Ji F, Gelev V, Sanglard D, Sanguinetti M, Sadreyev RI, Mukherjee G, Bhyravabhotla J, Buhrlage SJ, Gray NS, Wagner G, Näär AM, Arthanari H.

Nature. 2016 Feb 25;530(7591):485-9. doi: 10.1038/nature16963. Epub 2016 Feb 17.

PMID:
26886795
3.

Tipping the balance both ways: drug resistance and virulence in Candida glabrata.

Vale-Silva LA, Sanglard D.

FEMS Yeast Res. 2015 Jun;15(4):fov025. doi: 10.1093/femsyr/fov025. Epub 2015 May 15. Review.

4.

Evaluation of Etest performed in Mueller-Hinton agar supplemented with glucose for antifungal susceptibility testing of clinical isolates of filamentous fungi.

Pinto E, Lago M, Branco L, Vale-Silva LA, Pinheiro MD.

Mycopathologia. 2014 Apr;177(3-4):157-66. doi: 10.1007/s11046-014-9730-z. Epub 2014 Feb 26.

PMID:
24570038
5.

Molecular mechanisms of drug resistance in clinical Candida species isolated from Tunisian hospitals.

Eddouzi J, Parker JE, Vale-Silva LA, Coste A, Ischer F, Kelly S, Manai M, Sanglard D.

Antimicrob Agents Chemother. 2013 Jul;57(7):3182-93. doi: 10.1128/AAC.00555-13. Epub 2013 Apr 29.

6.

Aminodi(hetero)arylamines in the thieno[3,2-b]pyridine series: synthesis, effects in human tumor cells growth, cell cycle analysis, apoptosis and evaluation of toxicity using non-tumor cells.

Calhelha RC, Ferreira IC, Peixoto D, Abreu RM, Vale-Silva LA, Pinto E, Lima RT, Alvelos MI, Vasconcelos MH, Queiroz MJ.

Molecules. 2012 Mar 28;17(4):3834-43. doi: 10.3390/molecules17043834.

7.

Azole resistance by loss of function of the sterol Δ⁵,⁶-desaturase gene (ERG3) in Candida albicans does not necessarily decrease virulence.

Vale-Silva LA, Coste AT, Ischer F, Parker JE, Kelly SL, Pinto E, Sanglard D.

Antimicrob Agents Chemother. 2012 Apr;56(4):1960-8. doi: 10.1128/AAC.05720-11. Epub 2012 Jan 17.

8.

Comparison of the Etest and a rapid flow cytometry-based method with the reference CLSI broth microdilution protocol M27-A3 for the echinocandin susceptibility testing of Candida spp.

Vale-Silva LA, Pinto P, Lopes V, Ramos H, Pinto E.

Eur J Clin Microbiol Infect Dis. 2012 Jun;31(6):941-6. doi: 10.1007/s10096-011-1390-z. Epub 2011 Sep 10.

PMID:
21909651
9.

Nanoliposomes for encapsulation and delivery of the potential antitumoral methyl 6-methoxy-3-(4-methoxyphenyl)-1H-indole-2-carboxylate.

Abreu AS, Castanheira EM, Queiroz MJ, Ferreira PM, Vale-Silva LA, Pinto E.

Nanoscale Res Lett. 2011 Aug 3;6(1):482. doi: 10.1186/1556-276X-6-482.

10.

Synthesis and evaluation of tumor cell growth inhibition of methyl 3-amino-6-[(hetero)arylethynyl]thieno[3,2-b]pyridine-2-carboxylates. Structure-activity relationships, effects on the cell cycle and apoptosis.

Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, Almeida GM, Vasconcelos MH.

Eur J Med Chem. 2011 Jan;46(1):236-40. doi: 10.1016/j.ejmech.2010.11.009. Epub 2010 Dec 8.

PMID:
21138784
11.

Novel 6-[(hetero)arylamino]thieno[3,2-b]pyridines: synthesis and antitumoral activities.

Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, São-José Nascimento M.

Eur J Med Chem. 2010 Dec;45(12):5732-8. doi: 10.1016/j.ejmech.2010.09.030. Epub 2010 Sep 17.

PMID:
20934235
12.

Efficient synthesis of 6-(hetero)arylthieno[3,2-b]pyridines by Suzuki-Miyaura coupling. Evaluation of growth inhibition on human tumor cell lines, SARs and effects on the cell cycle.

Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, Lima RT, Vasconcelos MH.

Eur J Med Chem. 2010 Dec;45(12):5628-34. doi: 10.1016/j.ejmech.2010.09.014. Epub 2010 Sep 17.

PMID:
20926160
13.

Lycopersicon esculentum seeds: an industrial byproduct as an antimicrobial agent.

Taveira M, Silva LR, Vale-Silva LA, Pinto E, Valentão P, Ferreres F, Guedes de Pinho P, Andrade PB.

J Agric Food Chem. 2010 Sep 8;58(17):9529-36. doi: 10.1021/jf102215g.

PMID:
20707344
14.

Antifungal activity of the essential oil of Thymus x viciosoi against Candida, Cryptococcus, Aspergillus and dermatophyte species.

Vale-Silva LA, Gonçalves MJ, Cavaleiro C, Salgueiro L, Pinto E.

Planta Med. 2010 Jun;76(9):882-8. doi: 10.1055/s-0029-1240799. Epub 2010 Jan 26.

PMID:
20104443
15.

Synthesis of novel 3-(aryl)benzothieno[2,3-c]pyran-1-ones from Sonogashira products and intramolecular cyclization: Antitumoral activity evaluation.

Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, São-José Nascimento M.

Eur J Med Chem. 2009 May;44(5):1893-9. doi: 10.1016/j.ejmech.2008.11.002. Epub 2008 Nov 13.

PMID:
19070942
16.

Comparison of disk diffusion test and Etest for voriconazole and fluconazole susceptibility testing.

Buchta V, Vejsova M, Vale-Silva LA.

Folia Microbiol (Praha). 2008;53(2):153-60.

PMID:
18837162
17.

Antifungal activity of synthetic di(hetero)arylamines based on the benzo[b]thiophene moiety.

Pinto E, Queiroz MJ, Vale-Silva LA, Oliveira JF, Begouin A, Begouin JM, Kirsch G.

Bioorg Med Chem. 2008 Sep 1;16(17):8172-7. doi: 10.1016/j.bmc.2008.07.042. Epub 2008 Jul 20.

PMID:
18678498
18.
19.

Antifungal susceptibility testing by flow cytometry: is it the future?

Vale-Silva LA, Buchta V.

Mycoses. 2006 Jul;49(4):261-73. Review.

PMID:
16784439
20.

Investigation of the mechanism of action of 3-(4-bromophenyl)-5-acyloxymethyl-2,5-dihydrofuran-2-one against Candida albicans by flow cytometry.

Vale-Silva LA, Buchta V, Vokurková D, Pour M.

Bioorg Med Chem Lett. 2006 May 1;16(9):2492-5. Epub 2006 Feb 15.

PMID:
16480875
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