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Results: 1 to 20 of 48

1.

Fine-Mapping Additive and Dominant SNP Effects Using Group-LASSO and Fractional Resample Model Averaging.

Sabourin J, Nobel AB, Valdar W.

Genet Epidemiol. 2014 Nov 21. doi: 10.1002/gepi.21869. [Epub ahead of print]

PMID:
25417853
[PubMed - as supplied by publisher]
2.

Quantitative trait locus mapping methods for diversity outbred mice.

Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman KW, Churchill GA.

G3 (Bethesda). 2014 Sep 18;4(9):1623-33. doi: 10.1534/g3.114.013748.

PMID:
25237114
[PubMed - in process]
Free PMC Article
3.

Bayesian modeling of haplotype effects in multiparent populations.

Zhang Z, Wang W, Valdar W.

Genetics. 2014 Sep;198(1):139-56. doi: 10.1534/genetics.114.166249.

PMID:
25236455
[PubMed - in process]
Free PMC Article
4.

Midregional pro-adrenomedullin plasma concentrations are blunted in severe preeclampsia.

Matson BC, Corty RW, Karpinich NO, Murtha AP, Valdar W, Grotegut CA, Caron KM.

Placenta. 2014 Sep;35(9):780-3. doi: 10.1016/j.placenta.2014.07.003. Epub 2014 Jul 10.

PMID:
25043691
[PubMed - in process]
5.

Quantitative trait loci for energy balance traits in an advanced intercross line derived from mice divergently selected for heat loss.

Leamy LJ, Elo K, Nielsen MK, Thorn SR, Valdar W, Pomp D.

PeerJ. 2014 May 27;2:e392. doi: 10.7717/peerj.392. eCollection 2014.

PMID:
24918027
[PubMed]
Free PMC Article
6.

Genetics of adverse reactions to haloperidol in a mouse diallel: a drug-placebo experiment and Bayesian causal analysis.

Crowley JJ, Kim Y, Lenarcic AB, Quackenbush CR, Barrick CJ, Adkins DE, Shaw GS, Miller DR, de Villena FP, Sullivan PF, Valdar W.

Genetics. 2014 Jan;196(1):321-47. doi: 10.1534/genetics.113.156901. Epub 2013 Nov 15.

PMID:
24240528
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Using the emerging Collaborative Cross to probe the immune system.

Phillippi J, Xie Y, Miller DR, Bell TA, Zhang Z, Lenarcic AB, Aylor DL, Krovi SH, Threadgill DW, de Villena FP, Wang W, Valdar W, Frelinger JA.

Genes Immun. 2014 Jan;15(1):38-46. doi: 10.1038/gene.2013.59. Epub 2013 Nov 7.

PMID:
24195963
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Genetic architecture of skewed X inactivation in the laboratory mouse.

Calaway JD, Lenarcic AB, Didion JP, Wang JR, Searle JB, McMillan L, Valdar W, Pardo-Manuel de Villena F.

PLoS Genet. 2013;9(10):e1003853. doi: 10.1371/journal.pgen.1003853. Epub 2013 Oct 3.

PMID:
24098153
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Modeling host genetic regulation of influenza pathogenesis in the collaborative cross.

Ferris MT, Aylor DL, Bottomly D, Whitmore AC, Aicher LD, Bell TA, Bradel-Tretheway B, Bryan JT, Buus RJ, Gralinski LE, Haagmans BL, McMillan L, Miller DR, Rosenzweig E, Valdar W, Wang J, Churchill GA, Threadgill DW, McWeeney SK, Katze MG, Pardo-Manuel de Villena F, Baric RS, Heise MT.

PLoS Pathog. 2013 Feb;9(2):e1003196. doi: 10.1371/journal.ppat.1003196. Epub 2013 Feb 28.

PMID:
23468633
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Fine-mapping diabetes-related traits, including insulin resistance, in heterogeneous stock rats.

Solberg Woods LC, Holl KL, Oreper D, Xie Y, Tsaih SW, Valdar W.

Physiol Genomics. 2012 Nov 1;44(21):1013-26. doi: 10.1152/physiolgenomics.00040.2012. Epub 2012 Sep 4.

PMID:
22947656
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Recent developments in statistical methods for detecting genetic loci affecting phenotypic variability.

Rönnegård L, Valdar W.

BMC Genet. 2012 Jul 24;13:63. doi: 10.1186/1471-2156-13-63.

PMID:
22827487
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Reprioritizing genetic associations in hit regions using LASSO-based resample model averaging.

Valdar W, Sabourin J, Nobel A, Holmes CC.

Genet Epidemiol. 2012 Jul;36(5):451-62. doi: 10.1002/gepi.21639. Epub 2012 Apr 30.

PMID:
22549815
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Genome-wide association mapping of quantitative traits in outbred mice.

Zhang W, Korstanje R, Thaisz J, Staedtler F, Harttman N, Xu L, Feng M, Yanas L, Yang H, Valdar W, Churchill GA, Dipetrillo K.

G3 (Bethesda). 2012 Feb;2(2):167-74. doi: 10.1534/g3.111.001792. Epub 2012 Feb 1.

PMID:
22384395
[PubMed]
Free PMC Article
14.

High-resolution genetic mapping using the Mouse Diversity outbred population.

Svenson KL, Gatti DM, Valdar W, Welsh CE, Cheng R, Chesler EJ, Palmer AA, McMillan L, Churchill GA.

Genetics. 2012 Feb;190(2):437-47. doi: 10.1534/genetics.111.132597.

PMID:
22345611
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A general Bayesian approach to analyzing diallel crosses of inbred strains.

Lenarcic AB, Svenson KL, Churchill GA, Valdar W.

Genetics. 2012 Feb;190(2):413-35. doi: 10.1534/genetics.111.132563.

PMID:
22345610
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

High-resolution mapping of a complex disease, a model for rheumatoid arthritis, using heterogeneous stock mice.

Ahlqvist E, Ekman D, Lindvall T, Popovic M, Förster M, Hultqvist M, Klaczkowska D, Teneva I, Johannesson M, Flint J, Valdar W, Nandakumar KS, Holmdahl R.

Hum Mol Genet. 2011 Aug 1;20(15):3031-41. doi: 10.1093/hmg/ddr206. Epub 2011 May 12.

PMID:
21565963
[PubMed - indexed for MEDLINE]
Free Article
17.

Genome-wide and species-wide dissection of the genetics of arthritis severity in heterogeneous stock mice.

Johnsen AK, Valdar W, Golden L, Ortiz-Lopez A, Hitzemann R, Flint J, Mathis D, Benoist C.

Arthritis Rheum. 2011 Sep;63(9):2630-40. doi: 10.1002/art.30425.

PMID:
21560115
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Detecting major genetic loci controlling phenotypic variability in experimental crosses.

Rönnegård L, Valdar W.

Genetics. 2011 Jun;188(2):435-47. doi: 10.1534/genetics.111.127068. Epub 2011 Apr 5.

PMID:
21467569
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Genetic analysis of complex traits in the emerging Collaborative Cross.

Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, Powell CL, Steigerwalt J, Xie Y, Kelada SN, Collins FS, Yang IV, Schwartz DA, Branstetter LA, Chesler EJ, Miller DR, Spence J, Liu EY, McMillan L, Sarkar A, Wang J, Wang W, Zhang Q, Broman KW, Korstanje R, Durrant C, Mott R, Iraqi FA, Pomp D, Threadgill D, de Villena FP, Churchill GA.

Genome Res. 2011 Aug;21(8):1213-22. doi: 10.1101/gr.111310.110. Epub 2011 Mar 15.

PMID:
21406540
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Fine-mapping a locus for glucose tolerance using heterogeneous stock rats.

Solberg Woods LC, Holl K, Tschannen M, Valdar W.

Physiol Genomics. 2010 Mar 3;41(1):102-8. doi: 10.1152/physiolgenomics.00178.2009. Epub 2010 Jan 12.

PMID:
20068026
[PubMed - indexed for MEDLINE]
Free PMC Article

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