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Items: 1 to 20 of 143

1.

Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins.

Karvinen S, Silvennoinen M, Vainio P, Sistonen L, Koch LG, Britton SL, Kainulainen H.

Exp Gerontol. 2016 Mar 31;79:46-54. doi: 10.1016/j.exger.2016.03.015. [Epub ahead of print]

PMID:
27038700
2.

Citizen scientist lepidopterists exposed to potential carcinogens.

Vainio PJ, Vahlberg T, Liesivuori J.

Food Chem Toxicol. 2016 May;91:1-7. doi: 10.1016/j.fct.2016.03.001. Epub 2016 Mar 2.

PMID:
26945614
3.

Association between bone mineral density and lumbar disc degeneration.

Salo S, Leinonen V, Rikkonen T, Vainio P, Marttila J, Honkanen R, Tuppurainen M, Kröger H, Sirola J.

Maturitas. 2014 Dec;79(4):449-55. doi: 10.1016/j.maturitas.2014.09.003. Epub 2014 Sep 22.

PMID:
25266266
4.

Assessment of myocardial perfusion with MRI using a modified dual bolus method.

Husso M, Sipola P, Kuittinen T, Manninen H, Vainio P, Hartikainen J, Saarakkala S, Töyräs J, Kuikka J.

Physiol Meas. 2014 Apr;35(4):533-47. doi: 10.1088/0967-3334/35/4/533. Epub 2014 Feb 27.

PMID:
24577344
5.

Preclinical evaluation of a radioiodinated fully human antibody for in vivo imaging of vascular adhesion protein-1-positive vasculature in inflammation.

Autio A, Vainio PJ, Suilamo S, Mali A, Vainio J, Saanijoki T, Noponen T, Ahtinen H, Luoto P, Teräs M, Jalkanen S, Roivainen A.

J Nucl Med. 2013 Aug;54(8):1315-9. doi: 10.2967/jnumed.113.120295. Epub 2013 Jul 11.

6.

Transcriptional responses to hypoxia are enhanced by recurrent hypoxia (hypoxic preconditioning) in the epaulette shark.

Rytkönen KT, Renshaw GM, Vainio PP, Ashton KJ, Williams-Pritchard G, Leder EH, Nikinmaa M.

Physiol Genomics. 2012 Nov 15;44(22):1090-7. doi: 10.1152/physiolgenomics.00081.2012. Epub 2012 Sep 18.

7.

High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer.

Vainio P, Mpindi JP, Kohonen P, Fey V, Mirtti T, Alanen KA, Perälä M, Kallioniemi O, Iljin K.

PLoS One. 2012;7(6):e39801. doi: 10.1371/journal.pone.0039801. Epub 2012 Jun 28.

8.

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins.

Vainio P, Lehtinen L, Mirtti T, Hilvo M, Seppänen-Laakso T, Virtanen J, Sankila A, Nordling S, Lundin J, Rannikko A, Orešič M, Kallioniemi O, Iljin K.

Oncotarget. 2011 Dec;2(12):1176-90.

9.

15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.

Lehtinen L, Vainio P, Wikman H, Reemts J, Hilvo M, Issa R, Pollari S, Brandt B, Oresic M, Pantel K, Kallioniemi O, Iljin K.

J Pathol. 2012 Mar;226(4):674-86. doi: 10.1002/path.3956. Epub 2012 Jan 17.

PMID:
22072156
10.

Effect of nalmefene 20 and 80 mg on the corrected QT interval and T-wave morphology: a randomized, double-blind, parallel-group, placebo- and moxifloxacin-controlled, single-centre study.

Matz J, Graff C, Vainio PJ, Kallio A, Højer AM, Struijk JJ, Kanters JK, Andersen MP, Toft E.

Clin Drug Investig. 2011 Nov 1;31(11):799-811. doi: 10.2165/11592950-000000000-00000.

PMID:
21967071
11.

Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer.

Vainio P, Wolf M, Edgren H, He T, Kohonen P, Mpindi JP, Smit F, Verhaegh G, Schalken J, Perälä M, Iljin K, Kallioniemi O.

Prostate. 2012 May 15;72(7):789-802. doi: 10.1002/pros.21487. Epub 2011 Sep 14.

PMID:
21919029
12.

GTI: a novel algorithm for identifying outlier gene expression profiles from integrated microarray datasets.

Mpindi JP, Sara H, Haapa-Paananen S, Kilpinen S, Pisto T, Bucher E, Ojala K, Iljin K, Vainio P, Björkman M, Gupta S, Kohonen P, Nees M, Kallioniemi O.

PLoS One. 2011 Feb 18;6(2):e17259. doi: 10.1371/journal.pone.0017259. Erratum in: PLoS One. 2011;6(4). doi:10.1371/annotation/7d571883-faf0-4f66-86a2-806c36c4741c.

13.

Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer.

Vainio P, Gupta S, Ketola K, Mirtti T, Mpindi JP, Kohonen P, Fey V, Perälä M, Smit F, Verhaegh G, Schalken J, Alanen KA, Kallioniemi O, Iljin K.

Am J Pathol. 2011 Feb;178(2):525-36. doi: 10.1016/j.ajpath.2010.10.002.

14.

Monensin is a potent inducer of oxidative stress and inhibitor of androgen signaling leading to apoptosis in prostate cancer cells.

Ketola K, Vainio P, Fey V, Kallioniemi O, Iljin K.

Mol Cancer Ther. 2010 Dec;9(12):3175-85. doi: 10.1158/1535-7163.MCT-10-0368.

15.

FZD4 as a mediator of ERG oncogene-induced WNT signaling and epithelial-to-mesenchymal transition in human prostate cancer cells.

Gupta S, Iljin K, Sara H, Mpindi JP, Mirtti T, Vainio P, Rantala J, Alanen K, Nees M, Kallioniemi O.

Cancer Res. 2010 Sep 1;70(17):6735-45. doi: 10.1158/0008-5472.CAN-10-0244. Epub 2010 Aug 16.

16.

High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth.

Iljin K, Ketola K, Vainio P, Halonen P, Kohonen P, Fey V, Grafström RC, Perälä M, Kallioniemi O.

Clin Cancer Res. 2009 Oct 1;15(19):6070-8. doi: 10.1158/1078-0432.CCR-09-1035. Epub 2009 Sep 29.

17.

Assessment of splanchnic blood flow using magnetic resonance imaging.

Barthelmes D, Parviainen I, Vainio P, Vanninen R, Takala J, Ikonen A, Tueller D, Jakob SM.

Eur J Gastroenterol Hepatol. 2009 Jun;21(6):693-700. doi: 10.1097/MEG.0b013e32831a86e0.

PMID:
19293721
18.

Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues.

Kilpinen S, Autio R, Ojala K, Iljin K, Bucher E, Sara H, Pisto T, Saarela M, Skotheim RI, Björkman M, Mpindi JP, Haapa-Paananen S, Vainio P, Edgren H, Wolf M, Astola J, Nees M, Hautaniemi S, Kallioniemi O.

Genome Biol. 2008;9(9):R139. doi: 10.1186/gb-2008-9-9-r139. Epub 2008 Sep 19.

19.

Progression and determinants of quantitative magnetic resonance imaging measures of lumbar disc degeneration: a five-year follow-up of adult male monozygotic twins.

Videman T, Battié MC, Parent E, Gibbons LE, Vainio P, Kaprio J.

Spine (Phila Pa 1976). 2008 Jun 1;33(13):1484-90. doi: 10.1097/BRS.0b013e3181753bb1.

PMID:
18475246
20.

Targeting vascular adhesion protein-1 to treat autoimmune and inflammatory diseases.

Smith DJ, Vainio PJ.

Ann N Y Acad Sci. 2007 Sep;1110:382-8. Review.

PMID:
17911453
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