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Results: 1 to 20 of 140

1.

Assessment of myocardial perfusion with MRI using a modified dual bolus method.

Husso M, Sipola P, Kuittinen T, Manninen H, Vainio P, Hartikainen J, Saarakkala S, Töyräs J, Kuikka J.

Physiol Meas. 2014 Apr;35(4):533-47. doi: 10.1088/0967-3334/35/4/533. Epub 2014 Feb 27.

PMID:
24577344
[PubMed - in process]
2.

Preclinical evaluation of a radioiodinated fully human antibody for in vivo imaging of vascular adhesion protein-1-positive vasculature in inflammation.

Autio A, Vainio PJ, Suilamo S, Mali A, Vainio J, Saanijoki T, Noponen T, Ahtinen H, Luoto P, Teräs M, Jalkanen S, Roivainen A.

J Nucl Med. 2013 Aug;54(8):1315-9. doi: 10.2967/jnumed.113.120295. Epub 2013 Jul 11.

PMID:
23847292
[PubMed - indexed for MEDLINE]
3.

Transcriptional responses to hypoxia are enhanced by recurrent hypoxia (hypoxic preconditioning) in the epaulette shark.

Rytkönen KT, Renshaw GM, Vainio PP, Ashton KJ, Williams-Pritchard G, Leder EH, Nikinmaa M.

Physiol Genomics. 2012 Nov 15;44(22):1090-7. doi: 10.1152/physiolgenomics.00081.2012. Epub 2012 Sep 18.

PMID:
22991209
[PubMed - indexed for MEDLINE]
Free Article
4.

High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer.

Vainio P, Mpindi JP, Kohonen P, Fey V, Mirtti T, Alanen KA, Perälä M, Kallioniemi O, Iljin K.

PLoS One. 2012;7(6):e39801. doi: 10.1371/journal.pone.0039801. Epub 2012 Jun 28.

PMID:
22761906
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins.

Vainio P, Lehtinen L, Mirtti T, Hilvo M, Seppänen-Laakso T, Virtanen J, Sankila A, Nordling S, Lundin J, Rannikko A, Orešič M, Kallioniemi O, Iljin K.

Oncotarget. 2011 Dec;2(12):1176-90.

PMID:
22202492
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.

Lehtinen L, Vainio P, Wikman H, Reemts J, Hilvo M, Issa R, Pollari S, Brandt B, Oresic M, Pantel K, Kallioniemi O, Iljin K.

J Pathol. 2012 Mar;226(4):674-86. doi: 10.1002/path.3956. Epub 2012 Jan 17.

PMID:
22072156
[PubMed - indexed for MEDLINE]
7.

Effect of nalmefene 20 and 80 mg on the corrected QT interval and T-wave morphology: a randomized, double-blind, parallel-group, placebo- and moxifloxacin-controlled, single-centre study.

Matz J, Graff C, Vainio PJ, Kallio A, Højer AM, Struijk JJ, Kanters JK, Andersen MP, Toft E.

Clin Drug Investig. 2011 Nov 1;31(11):799-811. doi: 10.2165/11592950-000000000-00000.

PMID:
21967071
[PubMed - indexed for MEDLINE]
8.

Integrative genomic, transcriptomic, and RNAi analysis indicates a potential oncogenic role for FAM110B in castration-resistant prostate cancer.

Vainio P, Wolf M, Edgren H, He T, Kohonen P, Mpindi JP, Smit F, Verhaegh G, Schalken J, Perälä M, Iljin K, Kallioniemi O.

Prostate. 2012 May 15;72(7):789-802. doi: 10.1002/pros.21487. Epub 2011 Sep 14.

PMID:
21919029
[PubMed - indexed for MEDLINE]
9.

GTI: a novel algorithm for identifying outlier gene expression profiles from integrated microarray datasets.

Mpindi JP, Sara H, Haapa-Paananen S, Kilpinen S, Pisto T, Bucher E, Ojala K, Iljin K, Vainio P, Björkman M, Gupta S, Kohonen P, Nees M, Kallioniemi O.

PLoS One. 2011 Feb 18;6(2):e17259. doi: 10.1371/journal.pone.0017259. Erratum in: PLoS One. 2011;6(4). doi:10.1371/annotation/7d571883-faf0-4f66-86a2-806c36c4741c.

PMID:
21365010
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer.

Vainio P, Gupta S, Ketola K, Mirtti T, Mpindi JP, Kohonen P, Fey V, Perälä M, Smit F, Verhaegh G, Schalken J, Alanen KA, Kallioniemi O, Iljin K.

Am J Pathol. 2011 Feb;178(2):525-36. doi: 10.1016/j.ajpath.2010.10.002.

PMID:
21281786
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Monensin is a potent inducer of oxidative stress and inhibitor of androgen signaling leading to apoptosis in prostate cancer cells.

Ketola K, Vainio P, Fey V, Kallioniemi O, Iljin K.

Mol Cancer Ther. 2010 Dec;9(12):3175-85. doi: 10.1158/1535-7163.MCT-10-0368.

PMID:
21159605
[PubMed - indexed for MEDLINE]
Free Article
12.

FZD4 as a mediator of ERG oncogene-induced WNT signaling and epithelial-to-mesenchymal transition in human prostate cancer cells.

Gupta S, Iljin K, Sara H, Mpindi JP, Mirtti T, Vainio P, Rantala J, Alanen K, Nees M, Kallioniemi O.

Cancer Res. 2010 Sep 1;70(17):6735-45. doi: 10.1158/0008-5472.CAN-10-0244. Epub 2010 Aug 16.

PMID:
20713528
[PubMed - indexed for MEDLINE]
Free Article
13.

High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth.

Iljin K, Ketola K, Vainio P, Halonen P, Kohonen P, Fey V, Grafström RC, Perälä M, Kallioniemi O.

Clin Cancer Res. 2009 Oct 1;15(19):6070-8. doi: 10.1158/1078-0432.CCR-09-1035. Epub 2009 Sep 29.

PMID:
19789329
[PubMed - indexed for MEDLINE]
Free Article
14.

Assessment of splanchnic blood flow using magnetic resonance imaging.

Barthelmes D, Parviainen I, Vainio P, Vanninen R, Takala J, Ikonen A, Tueller D, Jakob SM.

Eur J Gastroenterol Hepatol. 2009 Jun;21(6):693-700. doi: 10.1097/MEG.0b013e32831a86e0.

PMID:
19293721
[PubMed - indexed for MEDLINE]
15.

Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues.

Kilpinen S, Autio R, Ojala K, Iljin K, Bucher E, Sara H, Pisto T, Saarela M, Skotheim RI, Björkman M, Mpindi JP, Haapa-Paananen S, Vainio P, Edgren H, Wolf M, Astola J, Nees M, Hautaniemi S, Kallioniemi O.

Genome Biol. 2008;9(9):R139. doi: 10.1186/gb-2008-9-9-r139. Epub 2008 Sep 19.

PMID:
18803840
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Progression and determinants of quantitative magnetic resonance imaging measures of lumbar disc degeneration: a five-year follow-up of adult male monozygotic twins.

Videman T, Battié MC, Parent E, Gibbons LE, Vainio P, Kaprio J.

Spine (Phila Pa 1976). 2008 Jun 1;33(13):1484-90. doi: 10.1097/BRS.0b013e3181753bb1.

PMID:
18475246
[PubMed - indexed for MEDLINE]
17.

Targeting vascular adhesion protein-1 to treat autoimmune and inflammatory diseases.

Smith DJ, Vainio PJ.

Ann N Y Acad Sci. 2007 Sep;1110:382-8. Review.

PMID:
17911453
[PubMed - indexed for MEDLINE]
18.

Chemically modified tetracycline (CMT)-3 inhibits histamine release and cytokine production in mast cells: possible involvement of protein kinase C.

Sandler C, Ekokoski E, Lindstedt KA, Vainio PJ, Finel M, Sorsa T, Kovanen PT, Golub LM, Eklund KK.

Inflamm Res. 2005 Jul;54(7):304-12.

PMID:
16134060
[PubMed - indexed for MEDLINE]
19.

Safety of blocking vascular adhesion protein-1 in patients with contact dermatitis.

Vainio PJ, Kortekangas-Savolainen O, Mikkola JH, Jaakkola K, Kalimo K, Jalkanen S, Veromaa T.

Basic Clin Pharmacol Toxicol. 2005 Jun;96(6):429-35.

PMID:
15910406
[PubMed - indexed for MEDLINE]
20.

Novel sulfhydryl-reactive compounds orazipone and OR-1958 inhibit cytokine production and histamine release in rat and human mast cells.

Vendelin J, Laitinen C, Vainio PJ, Nissinen E, Mäki T, Eklund KK.

Int Immunopharmacol. 2005 Jan;5(1):177-84.

PMID:
15589479
[PubMed - indexed for MEDLINE]

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