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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1912 1
1918 1
1919 2
1927 1
1933 1
1948 1
1967 1
1968 2
1971 1
1972 2
1973 2
1974 2
1975 9
1976 7
1977 11
1978 8
1979 9
1980 9
1981 16
1982 21
1983 22
1984 31
1985 30
1986 22
1987 32
1988 53
1989 60
1990 67
1991 64
1992 85
1993 79
1994 84
1995 84
1996 105
1997 101
1998 97
1999 128
2000 132
2001 150
2002 153
2003 155
2004 188
2005 184
2006 191
2007 196
2008 223
2009 245
2010 249
2011 286
2012 301
2013 300
2014 350
2015 408
2016 414
2017 504
2018 526
2019 599
2020 693
2021 782
2022 745
2023 836
2024 432

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9,469 results

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The following term was not found in PubMed: 20070185025
Page 1
Efficacy of Pembrolizumab in Patients With Noncolorectal High Microsatellite Instability/Mismatch Repair-Deficient Cancer: Results From the Phase II KEYNOTE-158 Study.
Marabelle A, Le DT, Ascierto PA, Di Giacomo AM, De Jesus-Acosta A, Delord JP, Geva R, Gottfried M, Penel N, Hansen AR, Piha-Paul SA, Doi T, Gao B, Chung HC, Lopez-Martin J, Bang YJ, Frommer RS, Shah M, Ghori R, Joe AK, Pruitt SK, Diaz LA Jr. Marabelle A, et al. J Clin Oncol. 2020 Jan 1;38(1):1-10. doi: 10.1200/JCO.19.02105. Epub 2019 Nov 4. J Clin Oncol. 2020. PMID: 31682550 Free PMC article. Clinical Trial.
A1/A2 astrocytes in central nervous system injuries and diseases: Angels or devils?
Fan YY, Huo J. Fan YY, et al. Neurochem Int. 2021 Sep;148:105080. doi: 10.1016/j.neuint.2021.105080. Epub 2021 May 25. Neurochem Int. 2021. PMID: 34048845 Review.
This article reviews the recent evidences regarding A1/A2 astrocytes, including (a) the specific markers and morphological characteristics, (b) the effects of A1/A2 astrocytes on the neurovascular unit, and (c) the molecular mechanisms involved in the phenotypic swi …
This article reviews the recent evidences regarding A1/A2 astrocytes, including (a) the specific markers and morphological characteri …
Novel Nitrile Peptidomimetics for Treating COVID-19.
Chia CSB. Chia CSB. ACS Med Chem Lett. 2022 Feb 3;13(3):330-331. doi: 10.1021/acsmedchemlett.2c00030. eCollection 2022 Mar 10. ACS Med Chem Lett. 2022. PMID: 35291756 Free PMC article.
This patent review reveals the structure-activity relationship of key inhibitors described in the patent WO 2021/250648 A1....
This patent review reveals the structure-activity relationship of key inhibitors described in the patent WO 2021/250648 A1....
Novel Halomethylketone Azadipeptides for Treating COVID-19.
Chia CSB, See YY. Chia CSB, et al. ACS Med Chem Lett. 2022 May 27;13(6):875-876. doi: 10.1021/acsmedchemlett.2c00136. eCollection 2022 Jun 9. ACS Med Chem Lett. 2022. PMID: 35707142 Free PMC article.
Less than a month after its patent application, Hoffmann La-Roche scientists filed a patent application describing azadipeptide peptidomimetic inhibitors (WO 2022/043374 A1). This patent highlight reveals the structure-activity relationship of key azadipeptide inhibitors d …
Less than a month after its patent application, Hoffmann La-Roche scientists filed a patent application describing azadipeptide peptidomimet …
8-Cyclopentyl-3-(3-[18F]fluoropropyl)-1-propylxanthine.
Leung K. Leung K. 2006 Feb 13 [updated 2006 Jul 8]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2006 Feb 13 [updated 2006 Jul 8]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641797 Free Books & Documents. Review.
A(1) receptors have been studied in vivo by positron emission tomography (PET) using [1-methyl-(11)C]8-dicyclopropylmethyl-1-methyl-3-propylxanthine ([18F]CPFPX ), a methyl xanthine analog of KF15372 with selective A(1) antagonistic activity (6). 8-Cyclopentyl-1,3-dipropylxanthin …
A(1) receptors have been studied in vivo by positron emission tomography (PET) using [1-methyl-(11)C]8-dicyclopropylmethyl-1-methyl-3-propyl …
Adenosine Augmentation Therapy.
Boison D. Boison D. In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012. In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012. PMID: 22787649 Free Books & Documents. Review.
Evaluation of WO 2012/177618 A1 and US-2014/0179750 A1: novel small molecule antagonists of prostaglandin-E2 receptor EP2.
Ganesh T. Ganesh T. Expert Opin Ther Pat. 2015 Jul;25(7):837-44. doi: 10.1517/13543776.2015.1025752. Epub 2015 Mar 15. Expert Opin Ther Pat. 2015. PMID: 25772215 Free PMC article.
The purpose of this article is to evaluate recently published patents WO 2012/177618 A1 and US-2014/0179750 A1 from Emory, which describe a number of cinnamic amide- and amide-derivatives as a potent antagonists of EP2 receptor, and their neuroprotective effe …
The purpose of this article is to evaluate recently published patents WO 2012/177618 A1 and US-2014/0179750 A1 from Emo …
On the adaptive nature of annexin-A1.
D'Acquisto F. D'Acquisto F. Curr Opin Pharmacol. 2009 Aug;9(4):521-8. doi: 10.1016/j.coph.2009.04.007. Epub 2009 May 27. Curr Opin Pharmacol. 2009. PMID: 19481503 Review.
Studies over the last decade have provided us with a wealth of evidence showing that Annexin-1 is a homeostatic endogenous anti-inflammatory mediator of the innate immune system. ...
Studies over the last decade have provided us with a wealth of evidence showing that Annexin-1 is a homeostatic endogenous anti-infla …
Therapeutic Implications of Germline Testing in Patients With Advanced Cancers.
Stadler ZK, Maio A, Chakravarty D, Kemel Y, Sheehan M, Salo-Mullen E, Tkachuk K, Fong CJ, Nguyen B, Erakky A, Cadoo K, Liu Y, Carlo MI, Latham A, Zhang H, Kundra R, Smith S, Galle J, Aghajanian C, Abu-Rustum N, Varghese A, O'Reilly EM, Morris M, Abida W, Walsh M, Drilon A, Jayakumaran G, Zehir A, Ladanyi M, Ceyhan-Birsoy O, Solit DB, Schultz N, Berger MF, Mandelker D, Diaz LA Jr, Offit K, Robson ME. Stadler ZK, et al. J Clin Oncol. 2021 Aug 20;39(24):2698-2709. doi: 10.1200/JCO.20.03661. Epub 2021 Jun 16. J Clin Oncol. 2021. PMID: 34133209 Free PMC article.
9,469 results