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Results: 1 to 20 of 267

1.

Structural basis for the recruitment of glycogen synthase by glycogenin.

Zeqiraj E, Tang X, Hunter RW, García-Rocha M, Judd A, Deak M, von Wilamowitz-Moellendorff A, Kurinov I, Guinovart JJ, Tyers M, Sakamoto K, Sicheri F.

Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):E2831-40. doi: 10.1073/pnas.1402926111. Epub 2014 Jun 30.

PMID:
24982189
[PubMed - in process]
2.

A loss of function analysis of host factors influencing Vaccinia virus replication by RNA interference.

Beard PM, Griffiths SJ, Gonzalez O, Haga IR, Pechenick Jowers T, Reynolds DK, Wildenhain J, Tekotte H, Auer M, Tyers M, Ghazal P, Zimmer R, Haas J.

PLoS One. 2014 Jun 5;9(6):e98431. doi: 10.1371/journal.pone.0098431. eCollection 2014.

PMID:
24901222
[PubMed - in process]
Free PMC Article
3.

Regulation of the histone deacetylase Hst3 by cyclin-dependent kinases and the ubiquitin ligase SCFCdc4.

Delgoshaie N, Tang X, Kanshin ED, Williams EC, Rudner AD, Thibault P, Tyers M, Verreault A.

J Biol Chem. 2014 May 9;289(19):13186-96. doi: 10.1074/jbc.M113.523530. Epub 2014 Mar 19.

PMID:
24648511
[PubMed - indexed for MEDLINE]
4.

BoxPlotR: a web tool for generation of box plots.

Spitzer M, Wildenhain J, Rappsilber J, Tyers M.

Nat Methods. 2014 Feb;11(2):121-2. doi: 10.1038/nmeth.2811. No abstract available.

PMID:
24481215
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin.

Huang H, Ceccarelli DF, Orlicky S, St-Cyr DJ, Ziemba A, Garg P, Plamondon S, Auer M, Sidhu S, Marinier A, Kleiger G, Tyers M, Sicheri F.

Nat Chem Biol. 2014 Feb;10(2):156-63. doi: 10.1038/nchembio.1412. Epub 2013 Dec 15.

PMID:
24316736
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Structure of an SspH1-PKN1 complex reveals the basis for host substrate recognition and mechanism of activation for a bacterial E3 ubiquitin ligase.

Keszei AF, Tang X, McCormick C, Zeqiraj E, Rohde JR, Tyers M, Sicheri F.

Mol Cell Biol. 2014 Feb;34(3):362-73. doi: 10.1128/MCB.01360-13. Epub 2013 Nov 18.

PMID:
24248594
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The PhosphoGRID Saccharomyces cerevisiae protein phosphorylation site database: version 2.0 update.

Sadowski I, Breitkreutz BJ, Stark C, Su TC, Dahabieh M, Raithatha S, Bernhard W, Oughtred R, Dolinski K, Barreto K, Tyers M.

Database (Oxford). 2013 May 13;2013:bat026. doi: 10.1093/database/bat026. Print 2013.

PMID:
23674503
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Systematic curation of protein and genetic interaction data for computable biology.

Dolinski K, Chatr-Aryamontri A, Tyers M.

BMC Biol. 2013 Apr 15;11:43. doi: 10.1186/1741-7007-11-43. Review. No abstract available.

PMID:
23587305
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A yeast chemical genetic screen identifies inhibitors of human telomerase.

Wong LH, Unciti-Broceta A, Spitzer M, White R, Tyers M, Harrington L.

Chem Biol. 2013 Mar 21;20(3):333-40. doi: 10.1016/j.chembiol.2012.12.008.

PMID:
23521791
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A strategy for modulation of enzymes in the ubiquitin system.

Ernst A, Avvakumov G, Tong J, Fan Y, Zhao Y, Alberts P, Persaud A, Walker JR, Neculai AM, Neculai D, Vorobyov A, Garg P, Beatty L, Chan PK, Juang YC, Landry MC, Yeh C, Zeqiraj E, Karamboulas K, Allali-Hassani A, Vedadi M, Tyers M, Moffat J, Sicheri F, Pelletier L, Durocher D, Raught B, Rotin D, Yang J, Moran MF, Dhe-Paganon S, Sidhu SS.

Science. 2013 Feb 1;339(6119):590-5. doi: 10.1126/science.1230161. Epub 2013 Jan 3.

PMID:
23287719
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The BioGRID interaction database: 2013 update.

Chatr-Aryamontri A, Breitkreutz BJ, Heinicke S, Boucher L, Winter A, Stark C, Nixon J, Ramage L, Kolas N, O'Donnell L, Reguly T, Breitkreutz A, Sellam A, Chen D, Chang C, Rust J, Livstone M, Oughtred R, Dolinski K, Tyers M.

Nucleic Acids Res. 2013 Jan;41(Database issue):D816-23. doi: 10.1093/nar/gks1158. Epub 2012 Nov 30.

PMID:
23203989
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Using ProHits to store, annotate, and analyze affinity purification-mass spectrometry (AP-MS) data.

Liu G, Zhang J, Choi H, Lambert JP, Srikumar T, Larsen B, Nesvizhskii AI, Raught B, Tyers M, Gingras AC.

Curr Protoc Bioinformatics. 2012 Sep;Chapter 8:Unit8.16. doi: 10.1002/0471250953.bi0816s39.

PMID:
22948730
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Analyzing protein-protein interactions from affinity purification-mass spectrometry data with SAINT.

Choi H, Liu G, Mellacheruvu D, Tyers M, Gingras AC, Nesvizhskii AI.

Curr Protoc Bioinformatics. 2012 Sep;Chapter 8:Unit8.15. doi: 10.1002/0471250953.bi0815s39.

PMID:
22948729
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

ALDH2 mediates 5-nitrofuran activity in multiple species.

Zhou L, Ishizaki H, Spitzer M, Taylor KL, Temperley ND, Johnson SL, Brear P, Gautier P, Zeng Z, Mitchell A, Narayan V, McNeil EM, Melton DW, Smith TK, Tyers M, Westwood NJ, Patton EE.

Chem Biol. 2012 Jul 27;19(7):883-92. doi: 10.1016/j.chembiol.2012.05.017.

PMID:
22840776
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

MolClass: a web portal to interrogate diverse small molecule screen datasets with different computational models.

Wildenhain J, Fitzgerald N, Tyers M.

Bioinformatics. 2012 Aug 15;28(16):2200-1. doi: 10.1093/bioinformatics/bts349. Epub 2012 Jun 17.

PMID:
22711790
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Protein interaction data curation: the International Molecular Exchange (IMEx) consortium.

Orchard S, Kerrien S, Abbani S, Aranda B, Bhate J, Bidwell S, Bridge A, Briganti L, Brinkman FS, Cesareni G, Chatr-aryamontri A, Chautard E, Chen C, Dumousseau M, Goll J, Hancock RE, Hannick LI, Jurisica I, Khadake J, Lynn DJ, Mahadevan U, Perfetto L, Raghunath A, Ricard-Blum S, Roechert B, Salwinski L, Stümpflen V, Tyers M, Uetz P, Xenarios I, Hermjakob H.

Nat Methods. 2012 Apr;9(4):345-50. doi: 10.1038/nmeth.1931. Erratum in: Nat Methods. 2012 Jun;9(6):626. Brinkman, Fiona [corrected to Brinkman, Fiona S L]; Hancock, Robert [corrected to Hancock, Robert E W].

PMID:
22453911
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Characterizing the roles of Met31 and Met32 in coordinating Met4-activated transcription in the absence of Met30.

Carrillo E, Ben-Ari G, Wildenhain J, Tyers M, Grammentz D, Lee TA.

Mol Biol Cell. 2012 May;23(10):1928-42. doi: 10.1091/mbc.E11-06-0532. Epub 2012 Mar 21.

PMID:
22438580
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

How to link ontologies and protein-protein interactions to literature: text-mining approaches and the BioCreative experience.

Krallinger M, Leitner F, Vazquez M, Salgado D, Marcelle C, Tyers M, Valencia A, Chatr-aryamontri A.

Database (Oxford). 2012 Mar 21;2012:bas017. doi: 10.1093/database/bas017. Print 2012.

PMID:
22438567
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Genome-wide Fitness Profiles Reveal a Requirement for Autophagy During Yeast Fermentation.

Piggott N, Cook MA, Tyers M, Measday V.

G3 (Bethesda). 2011 Oct;1(5):353-67. doi: 10.1534/g3.111.000836. Epub 2011 Oct 1.

PMID:
22384346
[PubMed]
Free PMC Article
20.

Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase.

Tang X, Orlicky S, Mittag T, Csizmok V, Pawson T, Forman-Kay JD, Sicheri F, Tyers M.

Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3287-92. doi: 10.1073/pnas.1116455109. Epub 2012 Feb 10.

PMID:
22328159
[PubMed - indexed for MEDLINE]
Free PMC Article

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