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Results: 1 to 20 of 169

1.

Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau.

Santa-Maria I, Alaniz ME, Renwick N, Cela C, Fulga TA, Van Vactor D, Tuschl T, Clark LN, Shelanski ML, McCabe BD, Crary JF.

J Clin Invest. 2015 Jan 9. pii: 78421. doi: 10.1172/JCI78421. [Epub ahead of print]

PMID:
25574843
[PubMed - as supplied by publisher]
2.

In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA.

La Rocca G, Olejniczak SH, González AJ, Briskin D, Vidigal JA, Spraggon L, DeMatteo RG, Radler MR, Lindsten T, Ventura A, Tuschl T, Leslie CS, Thompson CB.

Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):767-72. doi: 10.1073/pnas.1424217112. Epub 2015 Jan 7.

PMID:
25568082
[PubMed - in process]
3.

ELAVL1 Modulates Transcriptome-wide miRNA Binding in Murine Macrophages.

Lu YC, Chang SH, Hafner M, Li X, Tuschl T, Elemento O, Hla T.

Cell Rep. 2014 Dec 24;9(6):2330-43. doi: 10.1016/j.celrep.2014.11.030. Epub 2014 Dec 18.

PMID:
25533351
[PubMed - in process]
Free Article
4.

PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity.

Yoon JH, De S, Srikantan S, Abdelmohsen K, Grammatikakis I, Kim J, Kim KM, Noh JH, White EJ, Martindale JL, Yang X, Kang MJ, Wood WH 3rd, Noren Hooten N, Evans MK, Becker KG, Tripathi V, Prasanth KV, Wilson GM, Tuschl T, Ingolia NT, Hafner M, Gorospe M.

Nat Commun. 2014 Nov 4;5:5248. doi: 10.1038/ncomms6248.

PMID:
25366541
[PubMed - in process]
Free PMC Article
5.

A census of human RNA-binding proteins.

Gerstberger S, Hafner M, Tuschl T.

Nat Rev Genet. 2014 Dec;15(12):829-45. doi: 10.1038/nrg3813. Epub 2014 Nov 4.

PMID:
25365966
[PubMed - indexed for MEDLINE]
6.

Multiplexed miRNA fluorescence in situ hybridization for formalin-fixed paraffin-embedded tissues.

Renwick N, Cekan P, Bognanni C, Tuschl T.

Methods Mol Biol. 2014;1211:171-87. doi: 10.1007/978-1-4939-1459-3_14.

PMID:
25218385
[PubMed - in process]
7.

Evolutionary conservation and expression of human RNA-binding proteins and their role in human genetic disease.

Gerstberger S, Hafner M, Ascano M, Tuschl T.

Adv Exp Med Biol. 2014;825:1-55. doi: 10.1007/978-1-4939-1221-6_1. Review.

PMID:
25201102
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA.

Gao P, Zillinger T, Wang W, Ascano M, Dai P, Hartmann G, Tuschl T, Deng L, Barchet W, Patel DJ.

Cell Rep. 2014 Sep 25;8(6):1668-76. doi: 10.1016/j.celrep.2014.08.010. Epub 2014 Sep 4.

PMID:
25199835
[PubMed - in process]
Free Article
9.

MicroRNA-21 in Glomerular Injury.

Lai JY, Luo J, O'Connor C, Jing X, Nair V, Ju W, Randolph A, Ben-Dov IZ, Matar RN, Briskin D, Zavadil J, Nelson RG, Tuschl T, Brosius FC 3rd, Kretzler M, Bitzer M.

J Am Soc Nephrol. 2014 Aug 21. pii: ASN.2013121274. [Epub ahead of print]

PMID:
25145934
[PubMed - as supplied by publisher]
10.

A selective microRNA-based strategy inhibits restenosis while preserving endothelial function.

Santulli G, Wronska A, Uryu K, Diacovo TG, Gao M, Marx SO, Kitajewski J, Chilton JM, Akat KM, Tuschl T, Marks AR, Totary-Jain H.

J Clin Invest. 2014 Sep 2;124(9):4102-14. doi: 10.1172/JCI76069. Epub 2014 Aug 18.

PMID:
25133430
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Comparative RNA-sequencing analysis of myocardial and circulating small RNAs in human heart failure and their utility as biomarkers.

Akat KM, Moore-McGriff D, Morozov P, Brown M, Gogakos T, Correa Da Rosa J, Mihailovic A, Sauer M, Ji R, Ramarathnam A, Totary-Jain H, Williams Z, Tuschl T, Schulze PC.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11151-6. doi: 10.1073/pnas.1401724111. Epub 2014 Jul 10.

PMID:
25012294
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Deep MicroRNA sequencing reveals downregulation of miR-29a in neuroblastoma central nervous system metastasis.

Cheung IY, Farazi TA, Ostrovnaya I, Xu H, Tran H, Mihailovic A, Tuschl T, Cheung NK.

Genes Chromosomes Cancer. 2014 Oct;53(10):803-14. doi: 10.1002/gcc.22189. Epub 2014 Jun 5.

PMID:
24898736
[PubMed - in process]
13.

Identification of the RNA recognition element of the RBPMS family of RNA-binding proteins and their transcriptome-wide mRNA targets.

Farazi TA, Leonhardt CS, Mukherjee N, Mihailovic A, Li S, Max KE, Meyer C, Yamaji M, Cekan P, Jacobs NC, Gerstberger S, Bognanni C, Larsson E, Ohler U, Tuschl T.

RNA. 2014 Jul;20(7):1090-102. doi: 10.1261/rna.045005.114. Epub 2014 May 23.

PMID:
24860013
[PubMed - indexed for MEDLINE]
14.

Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function.

Karaca E, Weitzer S, Pehlivan D, Shiraishi H, Gogakos T, Hanada T, Jhangiani SN, Wiszniewski W, Withers M, Campbell IM, Erdin S, Isikay S, Franco LM, Gonzaga-Jauregui C, Gambin T, Gelowani V, Hunter JV, Yesil G, Koparir E, Yilmaz S, Brown M, Briskin D, Hafner M, Morozov P, Farazi TA, Bernreuther C, Glatzel M, Trattnig S, Friske J, Kronnerwetter C, Bainbridge MN, Gezdirici A, Seven M, Muzny DM, Boerwinkle E, Ozen M; Baylor Hopkins Center for Mendelian Genomics, Clausen T, Tuschl T, Yuksel A, Hess A, Gibbs RA, Martinez J, Penninger JM, Lupski JR.

Cell. 2014 Apr 24;157(3):636-50. doi: 10.1016/j.cell.2014.02.058.

PMID:
24766809
[PubMed - indexed for MEDLINE]
15.

Efficient solid-phase synthesis of pppRNA by using product-specific labeling.

Goldeck M, Tuschl T, Hartmann G, Ludwig J.

Angew Chem Int Ed Engl. 2014 Apr 25;53(18):4694-8. doi: 10.1002/anie.201400672. Epub 2014 Mar 25.

PMID:
24668741
[PubMed - in process]
16.

microRNAs are biomarkers of oncogenic human papillomavirus infections.

Wang X, Wang HK, Li Y, Hafner M, Banerjee NS, Tang S, Briskin D, Meyers C, Chow LT, Xie X, Tuschl T, Zheng ZM.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4262-7. doi: 10.1073/pnas.1401430111. Epub 2014 Mar 3.

PMID:
24591631
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

PAR-CLIP (Photoactivatable Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation): a step-by-step protocol to the transcriptome-wide identification of binding sites of RNA-binding proteins.

Spitzer J, Hafner M, Landthaler M, Ascano M, Farazi T, Wardle G, Nusbaum J, Khorshid M, Burger L, Zavolan M, Tuschl T.

Methods Enzymol. 2014;539:113-61. doi: 10.1016/B978-0-12-420120-0.00008-6.

PMID:
24581442
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Urine microRNA as potential biomarkers of autosomal dominant polycystic kidney disease progression: description of miRNA profiles at baseline.

Ben-Dov IZ, Tan YC, Morozov P, Wilson PD, Rennert H, Blumenfeld JD, Tuschl T.

PLoS One. 2014 Jan 29;9(1):e86856. doi: 10.1371/journal.pone.0086856. eCollection 2014.

PMID:
24489795
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Kruppel-like factor 15 is a critical regulator of cardiac lipid metabolism.

Prosdocimo DA, Anand P, Liao X, Zhu H, Shelkay S, Artero-Calderon P, Zhang L, Kirsh J, Moore D, Rosca MG, Vazquez E, Kerner J, Akat KM, Williams Z, Zhao J, Fujioka H, Tuschl T, Bai X, Schulze PC, Hoppel CL, Jain MK, Haldar SM.

J Biol Chem. 2014 Feb 28;289(9):5914-24. doi: 10.1074/jbc.M113.531384. Epub 2014 Jan 8.

PMID:
24407292
[PubMed - indexed for MEDLINE]
20.

Global target mRNA specification and regulation by the RNA-binding protein ZFP36.

Mukherjee N, Jacobs NC, Hafner M, Kennington EA, Nusbaum JD, Tuschl T, Blackshear PJ, Ohler U.

Genome Biol. 2014 Jan 8;15(1):R12. doi: 10.1186/gb-2014-15-1-r12.

PMID:
24401661
[PubMed - in process]
Free PMC Article

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