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Results: 1 to 20 of 70

1.

Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer.

Ben-Chetrit N, Chetrit D, Russell R, Körner C, Mancini M, Abdul-Hai A, Itkin T, Carvalho S, Cohen-Dvashi H, Koestler WJ, Shukla K, Lindzen M, Kedmi M, Lauriola M, Shulman Z, Barr H, Seger D, Ferraro DA, Pareja F, Gil-Henn H, Lapidot T, Alon R, Milanezi F, Symons M, Ben-Hamo R, Efroni S, Schmitt F, Wiemann S, Caldas C, Ehrlich M, Yarden Y.

Sci Signal. 2015 Jan 20;8(360):ra7. doi: 10.1126/scisignal.2005537.

PMID:
25605973
2.

Reactive oxygen species regulate hematopoietic stem cell self-renewal, migration and development, as well as their bone marrow microenvironment.

Ludin A, Gur-Cohen S, Golan K, Kaufmann KB, Itkin T, Medaglia C, Lu XJ, Ledergor G, Kollet O, Lapidot T.

Antioxid Redox Signal. 2014 Oct 10;21(11):1605-19. doi: 10.1089/ars.2014.5941. Epub 2014 Jun 26. Review.

PMID:
24762207
3.

Dynamic Cross Talk between S1P and CXCL12 Regulates Hematopoietic Stem Cells Migration, Development and Bone Remodeling.

Golan K, Kollet O, Lapidot T.

Pharmaceuticals (Basel). 2013 Sep 23;6(9):1145-69. doi: 10.3390/ph6091145.

4.

Egress and Mobilization of Hematopoietic Stem and Progenitor Cells: A Dynamic Multi-facet Process.

Lapid K, Glait-Santar C, Gur-Cohen S, Canaani J, Kollet O, Lapidot T.

StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008-.
2012 Dec 10.

5.

Fibroblast growth factor signaling promotes physiological bone remodeling and stem cell self-renewal.

Itkin T, Kaufmann KB, Gur-Cohen S, Ludin A, Lapidot T.

Curr Opin Hematol. 2013 May;20(3):237-44. doi: 10.1097/MOH.0b013e3283606162. Review.

PMID:
23567340
6.

GSK3β regulates physiological migration of stem/progenitor cells via cytoskeletal rearrangement.

Lapid K, Itkin T, D'Uva G, Ovadya Y, Ludin A, Caglio G, Kalinkovich A, Golan K, Porat Z, Zollo M, Lapidot T.

J Clin Invest. 2013 Apr;123(4):1705-17. doi: 10.1172/JCI64149. Epub 2013 Mar 8. Erratum in: J Clin Invest. 2013 Jul 1;123(7):3183.

7.

Cancer stem cell definitions and terminology: the devil is in the details.

Valent P, Bonnet D, De Maria R, Lapidot T, Copland M, Melo JV, Chomienne C, Ishikawa F, Schuringa JJ, Stassi G, Huntly B, Herrmann H, Soulier J, Roesch A, Schuurhuis GJ, Wöhrer S, Arock M, Zuber J, Cerny-Reiterer S, Johnsen HE, Andreeff M, Eaves C.

Nat Rev Cancer. 2012 Nov;12(11):767-75. doi: 10.1038/nrc3368. Epub 2012 Oct 11.

PMID:
23051844
8.

Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow.

Ludin A, Itkin T, Gur-Cohen S, Mildner A, Shezen E, Golan K, Kollet O, Kalinkovich A, Porat Z, D'Uva G, Schajnovitz A, Voronov E, Brenner DA, Apte RN, Jung S, Lapidot T.

Nat Immunol. 2012 Nov;13(11):1072-82. doi: 10.1038/ni.2408. Epub 2012 Sep 16.

PMID:
22983360
9.

Quantifying hematopoietic stem and progenitor cell mobilization.

Gur-Cohen S, Lapid K, Lapidot T.

Methods Mol Biol. 2012;904:15-35. doi: 10.1007/978-1-61779-943-3_2.

PMID:
22890919
10.

FGF signaling facilitates postinjury recovery of mouse hematopoietic system.

Zhao M, Ross JT, Itkin T, Perry JM, Venkatraman A, Haug JS, Hembree MJ, Deng CX, Lapidot T, He XC, Li L.

Blood. 2012 Aug 30;120(9):1831-42. doi: 10.1182/blood-2011-11-393991. Epub 2012 Jul 16.

11.

FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation.

Itkin T, Ludin A, Gradus B, Gur-Cohen S, Kalinkovich A, Schajnovitz A, Ovadya Y, Kollet O, Canaani J, Shezen E, Coffin DJ, Enikolopov GN, Berg T, Piacibello W, Hornstein E, Lapidot T.

Blood. 2012 Aug 30;120(9):1843-55. doi: 10.1182/blood-2011-11-394692. Epub 2012 May 29.

12.

The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells.

Maryanovich M, Oberkovitz G, Niv H, Vorobiyov L, Zaltsman Y, Brenner O, Lapidot T, Jung S, Gross A.

Nat Cell Biol. 2012 Mar 25;14(5):535-41. doi: 10.1038/ncb2468.

PMID:
22446738
13.

Regulatory cross talks of bone cells, hematopoietic stem cells and the nervous system maintain hematopoiesis.

Kollet O, Canaani J, Kalinkovich A, Lapidot T.

Inflamm Allergy Drug Targets. 2012 Jun;11(3):170-80. Review.

PMID:
22280241
14.

S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release.

Golan K, Vagima Y, Ludin A, Itkin T, Cohen-Gur S, Kalinkovich A, Kollet O, Kim C, Schajnovitz A, Ovadya Y, Lapid K, Shivtiel S, Morris AJ, Ratajczak MZ, Lapidot T.

Blood. 2012 Mar 15;119(11):2478-88. doi: 10.1182/blood-2011-06-358614. Epub 2012 Jan 25.

15.

CD45 regulates homing and engraftment of immature normal and leukemic human cells in transplanted immunodeficient mice.

Shivtiel S, Lapid K, Kalchenko V, Avigdor A, Goichberg P, Kalinkovich A, Nagler A, Kollet O, Lapidot T.

Exp Hematol. 2011 Dec;39(12):1161-1170.e1. doi: 10.1016/j.exphem.2011.08.012. Epub 2011 Sep 10.

PMID:
21911094
16.

Insights into the mechanism of enhanced mobilization of hematopoietic progenitor cells and release of CXCL12 by a combination of AMD3100 and aminoglycoside-polyarginine conjugates.

Berchanski A, Kalinkovich A, Ludin A, Lapidot T, Lapidot A.

FEBS J. 2011 Nov;278(21):4150-65. doi: 10.1111/j.1742-4658.2011.08348.x. Epub 2011 Oct 4.

PMID:
21910828
17.

MT1-MMP and RECK: opposite and essential roles in hematopoietic stem and progenitor cell retention and migration.

Golan K, Vagima Y, Goichberg P, Gur-Cohen S, Lapidot T.

J Mol Med (Berl). 2011 Dec;89(12):1167-74. doi: 10.1007/s00109-011-0792-9. Epub 2011 Aug 13. Review.

PMID:
21842347
18.

Chronic B cell deficiency from birth prevents age-related alterations in the B lineage.

Keren Z, Averbuch D, Shahaf G, Zisman-Rozen S, Golan K, Itkin T, Lapidot T, Mehr R, Melamed D.

J Immunol. 2011 Sep 1;187(5):2140-7. doi: 10.4049/jimmunol.1100999. Epub 2011 Aug 1.

19.

Neural regulation of bone, marrow, and the microenvironment.

Canaani J, Kollet O, Lapidot T.

Front Biosci (Schol Ed). 2011 Jun 1;3:1021-31. Review.

PMID:
21622251
20.

Pathways implicated in stem cell migration: the SDF-1/CXCR4 axis.

Vagima Y, Lapid K, Kollet O, Goichberg P, Alon R, Lapidot T.

Methods Mol Biol. 2011;750:277-89. doi: 10.1007/978-1-61779-145-1_19.

PMID:
21618098
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